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TRH
thyrotropin releasing hormone

The human orthologue of this gene is associated
with the following human disease:

Gene

Official Symbol	TRH
Official Full Name	thyrotropin releasing hormone
CGNC ID	6439
also known as	Pro-TRH, thyrotropin releasing hormone\|prepro-thyrotropin-releasing hormone\|pro-thyrotropin-releasing hormone\|prothyroliberin
gene type	protein-coding

Genomic Map

Sequence Information

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.19489

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	7200	ENSG00000170893	MIM:275120	MIM:613879
Mouse	22044	ENSMUSG00000005892	All phenotypic alleles (3):Targeted, knock-out(3)	MGI:98823
Xenopus	100127646, 397780, 373666			5805963
Zebrafish	266721	ENSDARG00000006868	ZDB-GENE-020930-1	ZFIN:ZDB-GENE-020930-1

Gene Ontology

Molecular Function	neuropeptide hormone activity
Biological Process	hormone-mediated signaling pathway
Cellular Component	extracellular region

Links to other databases

GEISHA Id	PREPROTRH.Vandenborne.2005	Data Source	Publication
Complete cDNA Template Probe	show ATTAAACATGCCTCTGCCACAATGGCTTTCCAAAAGACAACATCCTGGAAAAAGATACATAAGTGACCCGGAGAAGAGA CAGCATCCTGGAAAAAGAGATGTTGAGGAAAAAGCATCTTTTGGAGACATTCAGAAGAGACAGCATTTAGGGAAAACAG AAGTAGAAGGCTACCTTGTCAACTACCTGGAGCTGAAAAAGCGACAGCATCCTGGCAGAAGGTCACTGTGGGACCAGTC CACTGACATCTCTAGTTCACAGCTAACTTACTTAAATGAGTTATCCAAAAGACAGCATCCAGGCAGAAGATATCTGATG TATAAACACCAGCATCCTAGCAAGAGGGGCTGGAATGATGAGCTAGACCTAAGTGATCAAAACTGGGAGAAACATCAGC AGTTTGGAAACAGGGACAGGGATTCTGACAGCCCAGATTATACAGGTCCCTGTGACCTTCAGCAGTCTGCCATCTGTAA CAAAGACAGCTTGTTGCTTGACTTAGCAGAAAAGTTTAGCAAAGAGGGGGTAGAAGAAAAACATCAGCACCCAGGAAGG AGGTCAGCATGGGAGAATGAAACAGAGGAATGAGAAAGTAATTGTTT
Citation	Vandenborne K, Roelens SA, Darras VM, Kühn ER, Van der Geyten S. Cloning and hypothalamic distribution of the chicken thyrotropin-releasing hormone precursor cDNA. J Endocrinol. 2005 Aug;186(2):387-96.
Copyright	Copyright © 2012 by the Society for Endocrinology
Comments	The probe was amplified by PCR using the following primers: 5_-ATTAAACATGCCTCTGCC ACA-3_ and 5_-AAACAATT ACTTTCTCATTCCTCTG-3_ and was extracted from NCBI Acc# AB205116.1.