GEISHA - A Chicken Embryo Gene Expression Database
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PTN
pleiotrophin

Gene
Official SymbolPTN
Official Full Namepleiotrophin
CGNC ID50678
also known asHB-GAM, HBBM, HBGF-8, HBNF, OSF-1, pleiotrophin|heparin-binding brain mitogen|heparin-binding growth factor 8|heparin-binding growth-associated molecule|heparin-binding neutrophic factor|neurite growth-promoting factor 1|osteoblast-specific factor 1|pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_001276362
PolypeptideNP_001263291
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.39450
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human5764ENSG00000105894MIM:162095
Mouse19242ENSMUSG00000029838All phenotypic alleles (2):Targeted, knock-out(2) MGI:97804
Xenopus100101785, 444715481633
Zebrafish368211ENSDARG00000045798ZDB-GENE-030624-1ZFIN:ZDB-GENE-030624-1
Gene Ontology
Molecular Functiongrowth factor activity, heparin binding
Biological Processpositive regulation of cell division
Cellular Componentextracellular region
Links to other databases
Entrez Gene418125
Ensembl Gene
KEGGgga:418125

Entry 1

GEISHA IdHBGAM.Chambers.2006Data SourcePublication
Complete cDNA Template Probeshow
GGCGCGGGAGGAGTGGGGCGTGAGTCGGAGGTCCGTGGAGAAGCGGAGCCGCGGCGCCGTCAGCACCCGCAGCACCCGC
CGCGCACCGGGGACGCCCGCGGCTCGCCCCTTACAGCTGCGGGAGAAGCGCTTCTCGCCGCCCGAAAATGCCACAGCAA
CAACAGCAACGTCGAATGTTCACGGCTGCTCTCCTGGCACTTGTCTTCATTCTGGCAGCAGTGAGTACCACTGAGGCTG
GAAAGAAAGAGAAACCAGAGAAAAAGGCCAAGAAGTCTGACTGTGGGGAATGGCAGTGGAGTGTCTGTGTGCCCACCAA
TGGAGACTGTGGCCTGGGGACACGCGAGGGCACTCGCACTGGAGCAGAGTGCAAACAAACCACCAAGACTCAGAAGTGT
AAGATTCCCTGCAACTGGAAGAAGCAATTTGGAGCAGAGTGTAAATACCAATTCCAGGCCNNNNGAGAATGTGACTTGA
ATACTGCCTTGAAAACTCGAACNNNNNACCTAAAGAGAGCTCTTCATAATGCTGACTGCCAGAAGACTGTCACAATCTC
AAAGCCCTGTGGGAAGCTTACCAAACCCAAACCTCAA
CitationChambers, D, Mason, I, A high throughput messenger RNA differential display screen identifies discrete domains of gene expression and novel patterning processes along the developing neural tube. BMC Dev Biol. 2006; 6: 9. Published online 2006 February 24.
CopyrightCopyright © 2006 Chambers and Mason; licensee BioMed Central Ltd.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
CommentsAs insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #BI394859.1).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-11
stage 10
stage 10
stage 10
stage 11
stage 11
Neural Plate/Tube
Paraxial Mesoderm
 

Entry 2

GEISHA IdPTN.Lee.2012Data SourcePublication
Complete cDNA Template Probeshow
CCCAAACCTCAAGAATCCAAGAAGAAGAAAAAGGAAGGCAAGAAACAAGAGAAGATGCTGGATTAATGGAGCCAACTTG
GGCAATGTGAGAAAGGGACATCAGCAAACATGATCGGTTAACAGTTTCATTTATACCTAGGCATTTTACCCTAAAATTA
TTTATAGCTTAATGGTACAATAGAAGGAAACAAGCAAACACAGACAAAAAATATCCTTTTTTATTTACTTTAGTATTTT
TAATGTATAACCCTAACAACAATTTTAGAGGCCTGTCGTAAAGGATTCCAAACTCATTTAGAAAATTCTGTCTATTGCA
TATTGAACAGTGTAGAGGTTTTTAAAATATTTTTTTCTCAAGTCTTGCTGTAGGTCTCAGTCTTTTAACTACTCCATGC
AAGCAGAATTTGAACCTGTGTAGAGCCCTGCTGAACCCAGTGATAACCCTGTGTGGATGCAGGAGTCTGGTTGGGTGCA
GTTATATTTAAAATTAGGACCATATGAGTGAAACAACAAACAAATACTGTTTCTTAAGTTGTTGTTACATCTGGATAAC
TGTATGAAGTTATTTGTTTAAGGAGAGGATGGGGGCATTTTGTTGAGCATTTGCAGGCTAGGAATTTTTTTCTGTGTGT
GGTGAATGTTCATTCCAAACTGTAATAGTCTGGGTAAAAACAGTAGTGTTCATATCTTGGTTCCTGGCAGTAAAAATAG
TAAAATCTTTCAGTGGTTTGATATAGCAGGTTCCTAAACTTTTAGGTTTTTGTAGAAAAGGTATTTTCTACAAAAATAT
CTAGGTGGAAAGATAGCAAGACTCTTCTTCTTTACCGTATTGACACTGGTGAATGACAATGTCATCTGTTTTACCTGCA
AAAGCACAAACATGCTTTATTTCTTTCTTCCTTTTTAATTTATTTTTTATTTTTTTCCCCAGAATGGAGAATATCTTTT
TCATAAAAATCTAATTGAAATTGTTGCTATTCTACCTGACCCAACTCTCTTTTGTATTAGTGAGAATCTTCCTGCAGAT
TTTAACTATAACTGGTTGAAAGTAGAAATTATGTATAGTGGGAAGAAACAGAACAAATCAGTTTGGAAACTATCTAAGA
TGGCTCGTATTTCTGACCAGAAAAGGGGCACTTTATGAGACTTGAAACAAATAAGAATGAAATTAATTTTTAGTTTCAT
TTGTCTATTAGTAAAGCAGAAGGGAAATGTCAAGATGGTACCTTTTGCTTCCTTCCATTTTTAAATAAGTAAAAACACC
TTGGAAAATCTTAGCCATAAAGATATATTTTTTTCTTTTAATTTCATTTTTAACTCAAAAAGGAAAAAAATATAAAACC
TGTTGTTTTTCTGTTTTTTTTTACATATTTCAAATGATAATGAGTCCTGAGAAAAGTCAGAGTAGAAAAAAGATCTTGC
AATGAGTTGGTGTATCCTCAGGTGAAAGATTGTTTTACAAGCCAAACAACGTTCAGACCAGATATATTAGAAGAAACCT
ATGGGATTTCAAGTGCTCAAATTCTTTTAAAAACCACCCTTTAAAAATTATAAGTCTTAAATTTCGTAAGCAAGAAGTA
ACCTTCACTGTTGGTGTAGGCTCCAGGCTTTGCCTGCTGGTCAACAGGAAGTCTCCCAAAGTCTCCCTTTTGCTCCTGC
AGATACTCATTGACTTCAGTGAAACTTCATCAGGGTGCAATCATCTGGGTAAATCACAATGCTCTTTTGGAATTAGCTT
ATAGAAATGCAGAGTCTTTTACTGGTCTATCTTCTCACTTCCCTTTTCTAAGCAGAAAATAAAAATTAAAAAAAGCA
CitationLee JY, Jeong W, Lim W, Kim J, Bazer FW, Han JY, Song G.. Chicken Pleiotrophin: Regulation of Tissue Specific Expression by Estrogen in the Oviduct and Distinct Expression Pattern in the Ovarian Carcinomas. PLoS One. 2012; 7(4): e34215.
CopyrightCopyright Lee et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
CommentsAuthors indicated sense primer (5';-TGC TCT CCT GGC ACT TGT CT-3';), antisense primer (5';-CTT GGA TTC TTG AGG TTT GGG-3'). As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #XM_003640397.1 ).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
1
stage 1
stage 1
stage 1
stage 1
Intermediate Mesoderm
Isthmus
Magnum
Shell Gland

Entry 3

GEISHA IdPTN.Cui.2019Data SourcePublication
Complete cDNA Template Probeshow
ATGCCACAGCAACAACAGCAACGTCGAATGTTCACGGCTGCTCTCCTGGCACTTGTCTTCATTCTGGCAGCAGTGAGTA
CCACTGAGGCTGGAAAGAAAGAGAAACCAGAGAAAAAGGCCAAGAAGTCTGACTGTGGGGAATGGCAGTGGAGTGTCTG
TGTGCCCACCAATGGAGACTGTGGTCTGGGGACACGTGAGGGCACTCGCACTGGAGCAGAGTGCAAACAAACCACCAAG
ACTCAGAAGTGTAAGATTCCCTGCAACTGGAAGAAGCAATTTGGAGCAGAGTGTAAATACCAATTCCAGGCCTGGGGAG
AATGTGACTTGAATACTGCCTTGAAAACTCGAACTGGGAACCTAAAGAGAGCTCTTCATAATGCTGACTGCCAGAAGAC
TGTCACAATCTCAAAGCCCTGTGGGAAGCTTACCAAACCCAAACCTCAAGAATCCAAGAAGAAGAAAAAGGAAGGCAAG
AAACAAGAGAAGATGCTGGATTAA
CitationCui R, Lwigale P. Expression of the heparin-binding growth factors Midkine and pleiotrophin during ocular development. Gene Expr Patterns. 2019 Jun;32:28-37. Epub 2019 Feb 27. DOI: 10.1016/j.gep.2019.02.001.
CopyrightCopyright © 2019 Elsevier B.V. 
CommentsThe complete cDNA template sequence was obtained from the information provided in the publication as described in Cui et al. 2019. PTN is also known in NCBI as: HBBM; HBNF; OSF-1; HB-GAM; HBGF-8.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
19-24
stage 20
Unlabeled
 
25-30
stage 27
stage 27
Eye
Lens
on, optic nerve; nr, neural retina
pm, periocular; en, corneal endothelium
31-44
stage 31
stage 31
stage 36
stage 38
stage 38
stage 41
stage 44
Cranial Ganglia
Eye
Retina
gcl, ganglion cell layer
inl, inner nuclear layer; gcl, ganglion cell layer
onl, out nuclear layer; inl, inner nuclear layer
trigeminal ganglion
all
 
 
 
  
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.39450

Mouse

EmageMGI:97804
EurexpressMGI:97804
MGI GXDMGI:97804

Frog

Xenbase481633

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-030624-1
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