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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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SPI1
Spi-1 proto-oncogene

Gene

Official Symbol	SPI1
Official Full Name	Spi-1 proto-oncogene
CGNC ID	6161
also known as	transcription factor PU.1\|Spi-1/PU.1 transcription factor\|spleen focus forming virus (SFFV) proviral integration oncogene spi1, spleen focus forming virus (SFFV) , proviral integration oncogene spi1 , PU.1
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_205023
Polypeptide	NP_990354
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.1313

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	6688	ENSG00000066336		MIM:165170
Mouse	20375		All phenotypic alleles (18):Targeted, knock-out(8) Targeted, other(10)	MGI:98282
Xenopus	100125218			1018246
Zebrafish	30117, 751704	ENSDARG00000000767	ZDB-GENE-980526-164, ZDB-GENE-060825-351	ZFIN:ZDB-GENE-980526-164, ZFIN:ZDB-GENE-060825-351

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Links to other databases

Entrez Gene	395879
Ensembl Gene	ENSGALG00000008127
KEGG	gga:395879

Entry 1

GEISHA Id	ChEST673e10	Data Source	GEISHA ISH Analysis
Forward cDNA Template Probe	show GCTTGTTAGGGTTATTCTCCTATCCTGAGATCCACTACTGCAAAGGGACTTCACGGAGTCCAAGGATCTCACTTTTGTT CTTTTTTTTTTTTCTTTTTTCTCTTCATTGTTTTTGTTTGTTTCATGTGATTTTTCAAGTCAGTTATTCTGGATGTTTG AAAACTGAATTAAGAAAAATTCACTCTGAAATTGGCTGAATGTTGCAAGCTTGCAAAATGGAAGGATTTCCCCTCATTC CCCCTCCCTCTGAAGATATGGTGTCTTATGAGTCAGACCTCTACCGACAGCCCCATGACTATTACCAATATCTCAACAG TGATGGAGACAGTCATGGTGATCATTACTGGGAATATCATCCACACCACGTGCACAGTGAGTTTGAGACCTTTGGTGAT AACCACTTTACAGAACTGCAGAGCGTACAGCCTCCCCAGCTGCAGCAGCTCTACAGGCACATGGAGATCGAACAAATGC ACGTCTTGGATTCTGCAATCCCAACCACACATATTGGACTCAACCATCAGGTTTCCTATTTGCCTCGGATGTGCCTACA GTACTCCTCTCCACCACAGCCCAGTTCTGATGAGGAGGACATTGAGAGGCAGAGCCCACCACTGGAGGTATCAGATGGG GAGACTGATGGTGTGGACCCTGGGCCTGGAATCATGCATGGTGAAACAGGCAGCAAGAAAAAGATACGTCTGTATCAGT TCCTTCTGGACCTTCTTCGCAGTGGAGACATGAAGGACAGCATCTGGTGGGTAGATAAAGAAAAAGGTACTTTCCAGTT CTCCTCCAAACACAAAGAAGCATTGGCACATCGCTGGGGCATACAAAAAGGCAATCGCAAGAAAATGACCTACCAGAAG ATGGCACGGGCTTTGAGAAACTACCGCCAGAAAGGGGGAATCAAGAAGGTCAAGAAGAAGCTGAACTACCAGTTTAATG GAAAAGTGAAGGGAAAGGGGGTCCCTAATAGAAGCATTATCCTCACTGAGGCCACGGAACCTAAACAAAAAAATATTAA AACCTCCTGGTTGAAACCAGCAAAGAAAAGGACACCTCTTTTTCTTTGCTCCTGGGCCCCCTTCTCTGCCTTAAAGGGC CTTTACATAAAAAGTTTCGGGAAAAATTCCCTTTTCTCCTCTTAAAAACCAAACTGAACAATTTTTTCTTCCTCCTAAA TGGGACAAATTGGAAATTAACCAATTACAAATATTATTGCCCACAAATTTTTTTATGTTTG
Comments	Labeled cells unknown type.

Stage

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Location (click to highlight)

Comments (click to highlight)

13-18

stage 18

Blood Islands
Extraembryonic

Isolated cells

19-21

stage 21

Blood

Entry 2

GEISHA Id	PU1.Bollerot.2005	Data Source	Publication
Complete cDNA Template Probe	show AATTCCAACCTATTAGGGCAAACTATGAAAACTTGTTAGGGTTATTCTCCTATCCTGAGATCCACTACTGCAAAGGGAC TTCACGGAGTCCAAGGATCTCACTTTTGGTCTTTTTTTTTTTTCTTTTTTCTCTTCATTGTTTTGGGTTGTTTCATGTG ATTTTTCAAGTCAGTTATTCTGGATGTTTGAAAACTGAATTAAGAAAAATTCACTCTGAAATTGGCTGAATGTTGCAAG CTTGCAAAATGGAAGGATTTCCCCTCATTCCCCCTCCCTCTGAAGATATGGTGTCTTATGAGTCAGACCTCTACCGACA GCCCCATGACTATTACCAATATCTCAACAGTGATGGAGACAGTCATGGTGATCATTACTGGGAATATCATCCACACCAC GTGCACAGTGAGTTTGAGACCTTTGGTGATAACCACTTTACAGAACTGCAGAGCGTACAGCCTCCCCAGCTGCAGCAGC TCTACAGGCACATGGAGATCGAACAAATGCACGTCTTGGATTCTGCAATCCCAACCACACATATTGGTCTCACCCATCA GTACTCCTCTCCACCACAGCCCAGTTCTGATGAGGAGGACATTGAGAGGCAGAGCCCACCACTGGAGGTATCAGATGGG GAGACTGATGGTGTGGACCCTGGGCCTGGAATCATGCATGGTGAAACAGGCAGCAAGAAAAAGATACGTCTGTATCAGT TCCTTCTGGACCTTCTTCGCAGTGGAGACATGAAGGACAGCATCTGGTGGGTAGATAAAGAAAAAGGTACTTTCCAGTT CTCCTCCAAACACAAAGAAGCATTGGCACATCGCTGGGGCATACAGAAAGGCAATCGCAAGAAAATGACCTACCAGAAG ATGGCACGGGCTTTGAGAAACTACGGCAAGACAGGGGAAGTCAAGAAGGTCAAGAAGAAGCTGACCTACCAGTTTAGTG GTGAGGTGATGGGAAGGGGGGTCGCTGATAGGAAGCATTACCCTCACTGAGCCCACGGGACCCTAAGCAAAAAAATATT AAGACCTCCTGGTTGAAAACCAGCAGAGGAGATGGACGCGTCTTTCTCTTTGCTTCCTGTGCCCCCTTCTGCCTCTAAA GGGCCTTTACCATCAGATGTTTCTGGTACGAATTCTTTGCTTCCATCCTACAAATTGGACAGAGTTGGGAAATATAAGC GATGTACAAATATATTATTGTCGTCAAAGATTTTTTTGATTGTATTGTAACTAAAGAATACAGCTGATGAAGTTTTGCC TTCAAGGGTGGTGCTGTGTCACTCACAGTGACACTGCATTAGCTTACAGCTTTCAAACTAGCATTAATACAGGCTCTGC CGCAGCTCTCAAAGCTAGAGAGAAGTTTGCAGATCTGAGAATGATACTGGTTCTTTTAAATAGTAATAACATGTACATA TTTAATAAAATTTGATATAATTAAAAAAAAAAAAA
Citation	Bollerot K, Romero S, Dunon D, Jaffredo T. Core binding factor in the early avian embryo: cloning of Cbfbeta and combinatorial expression patterns with Runx1. Gene Expr Patterns. 2005 Dec;6(1):29-39. Epub 2005 Jul 19.
Copyright	Copyright © 2005 Elsevier B.V. All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205023).

Stage

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Location (click to highlight)

Comments (click to highlight)

13-14

stage 14

Blood Islands

Figure 6 compares PU.1 expression to Cbfβ, Runx1, and c-Myb.

Entry 3

GEISHA Id	Pu-1.Jaffredo.2005	Data Source	Publication
Complete cDNA Template Probe	show AATTCCAACCTATTAGGGCAAACTATGAAAACTTGTTAGGGTTATTCTCCTATCCTGAGATCCACTACTGCAAAGGGAC TTCACGGAGTCCAAGGATCTCACTTTTGGTCTTTTTTTTTTTTCTTTTTTCTCTTCATTGTTTTGGGTTGTTTCATGTG ATTTTTCAAGTCAGTTATTCTGGATGTTTGAAAACTGAATTAAGAAAAATTCACTCTGAAATTGGCTGAATGTTGCAAG CTTGCAAAATGGAAGGATTTCCCCTCATTCCCCCTCCCTCTGAAGATATGGTGTCTTATGAGTCAGACCTCTACCGACA GCCCCATGACTATTACCAATATCTCAACAGTGATGGAGACAGTCATGGTGATCATTACTGGGAATATCATCCACACCAC GTGCACAGTGAGTTTGAGACCTTTGGTGATAACCACTTTACAGAACTGCAGAGCGTACAGCCTCCCCAGCTGCAGCAGC TCTACAGGCACATGGAGATCGAACAAATGCACGTCTTGGATTCTGCAATCCCAACCACACATATTGGTCTCACCCATCA GTACTCCTCTCCACCACAGCCCAGTTCTGATGAGGAGGACATTGAGAGGCAGAGCCCACCACTGGAGGTATCAGATGGG GAGACTGATGGTGTGGACCCTGGGCCTGGAATCATGCATGGTGAAACAGGCAGCAAGAAAAAGATACGTCTGTATCAGT TCCTTCTGGACCTTCTTCGCAGTGGAGACATGAAGGACAGCATCTGGTGGGTAGATAAAGAAAAAGGTACTTTCCAGTT CTCCTCCAAACACAAAGAAGCATTGGCACATCGCTGGGGCATACAGAAAGGCAATCGCAAGAAAATGACCTACCAGAAG ATGGCACGGGCTTTGAGAAACTACGGCAAGACAGGGGAAGTCAAGAAGGTCAAGAAGAAGCTGACCTACCAGTTTAGTG GTGAGGTGATGGGAAGGGGGGTCGCTGATAGGAAGCATTACCCTCACTGAGCCCACGGGACCCTAAGCAAAAAAATATT AAGACCTCCTGGTTGAAAACCAGCAGAGGAGATGGACGCGTCTTTCTCTTTGCTTCCTGTGCCCCCTTCTGCCTCTAAA GGGCCTTTACCATCAGATGTTTCTGGTACGAATTCTTTGCTTCCATCCTACAAATTGGACAGAGTTGGGAAATATAAGC GATGTACAAATATATTATTGTCGTCAAAGATTTTTTTGATTGTATTGTAACTAAAGAATACAGCTGATGAAGTTTTGCC TTCAAGGGTGGTGCTGTGTCACTCACAGTGACACTGCATTAGCTTACAGCTTTCAAACTAGCATTAATACAGGCTCTGC CGCAGCTCTCAAAGCTAGAGAGAAGTTTGCAGATCTGAGAATGATACTGGTTCTTTTAAATAGTAATAACATGTACATA TTTAATAAAATTTGATATAATTAAAAAAAAAAAAA
Citation	Jaffredo T, Bollerot K, Sugiyama D, Gautier R, Drevon C (2005). Tracing the hemangioblast during embryogenesis: developmental relationships between endothelial and hematopoietic cells. Int J Dev Biol. 2005;49(2-3):269-77.
Copyright	"Reprinted from Int. J. Dev. Biol., 49,Jaffredo T, Bollerot K, Sugiyama D, Gautier R, Drevon C , Tracing the hemangioblast during embryogenesis: developmental relationships between endothelial and hematopoietic cells, 269-77, Copyright (2005), with permission from Copyright © 2005 UBC Press". All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_205023).

Stage

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Location (click to highlight)

Comments (click to highlight)

13-18

stage 18

Aorta

31-44

stage 44

Aorta
Blood

Comparison with other genes

Entry 4

GEISHA Id	SPI1.Kherrouche.1998	Data Source	Publication
Complete cDNA Template Probe	show AATTCCAACCTATTAGGGCAAACTATGAAAACTTGTTAGGGTTATTCTCCTATCCTGAGATCCACTACTGCAAAGGGAC TTCACGGAGTCCAAGGATCTCACTTTTGGTCTTTTTTTTTTTTCTTTTTTCTCTTCATTGTTTTGGGTTGTTTCATGTG ATTTTTCAAGTCAGTTATTCTGGATGTTTGAAAACTGAATTAAGAAAAATTCACTCTGAAATTGGCTGAATGTTGCAAG CTTGCAAAATGGAAGGATTTCCCCTCATTCCCCCTCCCTCTGAAGATATGGTGTCTTATGAGTCAGACCTCTACCGACA GCCCCATGACTATTACCAATATCTCAACAGTGATGGAGACAGTCATGGTGATCATTACTGGGAATATCATCCACACCAC GTGCACAGTGAGTTTGAGACCTTTGGTGATAACCACTTTACAGAACTGCAGAGCGTACAGCCTCCCCAGCTGCAGCAGC TCTACAGGCACATGGAGATCGAACAAATGCACGTCTTGGATTCTGCAATCCCAACCACACATATTGGTCTCACCCATCA GTACTCCTCTCCACCACAGCCCAGTTCTGATGAGGAGGACATTGAGAGGCAGAGCCCACCACTGGAGGTATCAGATGGG GAGACTGATGGTGTGGACCCTGGGCCTGGAATCATGCATGGTGAAACAGGCAGCAAGAAAAAGATACGTCTGTATCAGT TCCTTCTGGACCTTCTTCGCAGTGGAGACATGAAGGACAGCATCTGGTGGGTAGATAAAGAAAAAGGTACTTTCCAGTT CTCCTCCAAACACAAAGAAGCATTGGCACATCGCTGGGGCATACAGAAAGGCAATCGCAAGAAAATGACCTACCAGAAG ATGGCACGGGCTTTGAGAAACTACGGCAAGACAGGGGAAGTCAAGAAGGTCAAGAAGAAGCTGACCTACCAGTTTAGTG GTGAGGTGATGGGAAGGGGGGTCGCTGATAGGAAGCATTACCCTCACTGAGCCCACGGGACCCTAAGCAAAAAAATATT AAGACCTCCTGGTTGAAAACCAGCAGAGGAGATGGACGCGTCTTTCTCTTTGCTTCCTGTGCCCCCTTCTGCCTCTAAA GGGCCTTTACCATCAGATGTTTCTGGTACGAATTCTTTGCTTCCATCCTACAAATTGGACAGAGTTGGGAAATATAAGC GATGTACAAATATATTATTGTCGTCAAAGATTTTTTTGATTGTATTGTAACTAAAGAATACAGCTGATGAAGTTTTGCC TTCAAGGGTGGTGCTGTGTCACTCACAGTGACACTGCATTAGCTTACAGCTTTCAAACTAGCATTAATACAGGCTCTGC CGCAGCTCTCAAAGCTAGAGAGAAGTTTGCAGATCTGAGAATGATACTGGTTCTTTTAAATAGTAATAACATGTACATA TTTAATAAAATTTGATATAATTAAAAAAAAAAAAA
Citation	Kherrouche Z, Beuscart A, Huguet C, Flourens A, Moreau-Gachelin F, Stehelin D, Coll J. Isolation and characterization of a chicken homologue of the Spi-1/PU.1 transcription factor. Oncogene. 1998 Mar 12
Copyright	Copyright © 2007 UBC Press