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PAX1 Gene Summary Expression Other Species Expression JBrowse Gene Official Symbol PAX1 Official Full Name paired box 1 CGNC ID 63989 also known as GPX-1, Pax-1, paired box protein Pax-1|Paired box protein Pax-1 gene type protein-coding
Genomic Map Sequence Information Gene Expression In Situ Hybridization GEISHA EST Profile
Orthology Entrez Gene Ensembl Gene Genetic Phenotypes MOD Fruit Fly Human Mouse Xenopus Zebrafish
Gene Ontology Molecular Function Biological Process Cellular Component
Links to other databases
Entry 1 GEISHA Id PAX1.Bothe.2007 Data Source Publication Complete cDNA Template Probe show CTTTCACAATTTTCCCTCCCCATCGCCTCCCTCGCGGGGCACTGACACTCTCCCCGCCCGGCCCATCGCGGCCCGGCAG
Citation Bothe I, Ahmed MU, Winterbottom FL, von Scheven G, Dietrich S. Extrinsic versus intrinsic cues in avian paraxial mesoderm patterning and differentiation. Dev Dyn. 2007 Sep;236(9):2397-409. Copyright Copyright © 2007 Wiley-Liss, Inc. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc # U22046). Note: this is quail sequence.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-15
stage 15
stage 15
stage 15
Sclerotome
Entry 2 GEISHA Id PAX1.Lin.2007 Data Source Publication Complete cDNA Template Probe show AGATCCTGGCCCGCTACAACGAGACCGGCTCCATCCTGCCCGGAGCCATCGGAGGCAGCAAGCCGCGGGTCACCACCCC
Citation Lin J, Redies C, Luo J. Regionalized expression of ADAM13 during chicken embryonic development. Dev Dyn. 2007 Mar;236(3):862-70. Copyright Copyright © 2007 Wiley-Liss, Inc. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (U22046). The primers used were 5'-AGATCCTGGCCCGCTACAACGAGA-3' as the forward primer, and 5'-TGGGCGGAAGGGAAGGCAGTC-3' as the reverse primer.
Entry 3 GEISHA Id PAX1.Huang.2003 Data Source Publication Complete cDNA Template Probe show CTTTCACAATTTTCCCTCCCCATCGCCTCCCTCGCGGGGCACTGACACTCTCCCCGCCCGGCCCATCGCGGCCCGGCAG
Citation Huang R, Stolte D, Kurz H, Ehehalt F, Cann GM, Stockdale FE, Patel K, Christ B. Ventral axial organs regulate expression of myotomal Fgf-8 that influences rib development. Dev Biol. 2003 Mar 1;255(1):30-47. Copyright Copyright © 2003 Elsevier Science (USA) All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (U22046).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19 stage 19
Leg Somites
Entry 4 GEISHA Id PAX1.Grevellec.2011 Data Source Publication Complete cDNA Template Probe show CGGGCGGAGGGTGCCGAGTCCTCTCCAGGTCCCCCCGGCGGCCGCGGGGAGCGGCCGCCGCGGCCATTTAGGAGCGGAG
Citation Grevellec A, Graham A, Tucker AS. Shh signalling restricts the expression of Gcm2 and controls the position of the developing parathyroids. Dev Biol. 2011 May 15;353(2):194-205. Epub 2011 Feb 22. Copyright Copyright © 2011 Elsevier Inc. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # XM_003640897.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-24 stage 24
stage 24
Pharyngeal Arches and Clefts
Entry 5 GEISHA Id PAX1.Moeller.2003 Data Source Publication Complete cDNA Template Probe show ATGGGCAGTTGGGAAAGGCGAGTTTTGCTCCAAGAAGGCCTTAAAAAAAAGAAAAACACAGGGAAAGACATTGACATTG
Citation Moeller C, Swindell EC, Kispert A, Eichele G
Carboxypeptidase Z (CPZ) modulates Wnt signaling and regulates the development of skeletal elements in the chicken. Development. 2003 Nov;130(21):5103-11. Epub 2003 Aug 27
Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (Acc. # XM_003640897.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 31-36 stage 36
stage 36
Wing Mesenchyme
Entry 6 GEISHA Id PAX1.Senthinathan.2012 Data Source Publication Complete cDNA Template Probe show CTTTCACAATTTTCCCTCCCCATCGCCTCCCTCGCGGGGCACTGACACTCTCCCCGCCCGGCCCATCGCGGCCCGGCAG
Citation Senthinathan B, Sousa C, Tannahill D, Keynes R. The generation of vertebral segmental patterning in the chick embryo. J Anat. 2012 Jun;220(6):591-602. Copyright © 2012 The Authors. Journal of Anatomy © 2012 Anatomical Society. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc #U22046.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-18 stage 13
stage 13
Sclerotome 19-24 stage 24
Sclerotome 25-30 stage 25
stage 25
stage 29
stage 29
stage 29
stage 29
stage 29
stage 30
Somites Spinal Ganglia and Nerves
Entry 7 GEISHA Id PAX1.Malashichev.2005 Data Source Publication Complete cDNA Template Probe show ATGCGGCGTTCGGGCGGGCGCGATGCTGCGATCTCCGCTGACATCTTGTGGCCGGGCCCCGCATCTCTCCATCTCCGCT
Citation Malashichev Y, Borkhvardt V, Christ B, Scaal M. Differential regulation of avian pelvic girdle development by the limb field ectoderm. Anat Embryol (Berl). 2005 Oct;210(3):187-97. Epub 2005 Oct 18. Copyright © Springer, Part of Springer Science+Business Media Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence was obtained from NCBI (Acc. # XM_003640897.2).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-29 stage 26
stage 27
stage 28
stage 29
Limb Buds Paraxial Mesoderm
Entry 8 GEISHA Id Pax-1.Hsu.1997 Data Source Publication Complete cDNA Template Probe show CGGGCGGAGGGTGCCGAGTCCTCTCCAGGTCCCCCCGGCGGCCGCGGGGAGCGGCCGCCGCGGCCATTTAGGAGCGGAG
Citation Hsu CW, Tuan RS. Whole-mount in situ hybridization for developing chick embryos using digoxygenin-labeled RNA probes. Methods Mol Biol. 1997;63:263-70. Copyright copyright © Humana Press Inc., Totowa, NJ 1997 Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (XM_015283428.2 ).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-24 stage 23
stage 23
Somites 31-44 stage 44
Entry 9 GEISHA Id Pax-1.Cauthen.2001 Data Source Publication Complete cDNA Template Probe show CGGGCGGAGGGTGCCGAGTCCTCTCCAGGTCCCCCCGGCGGCCGCGGGGAGCGGCCGCCGCGGCCATTTAGGAGCGGAG
Citation Cauthen CA, Berdougo E, Sandler J, Burrus LW. Comparative analysis of the expression patterns of Wnts and Frizzleds during early myogenesis in chick embryos. Mech Dev. 2001 Jun;104(1-2):133-8. Copyright Copyright © 2001 Elsevier Science Ireland Ltd. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (XM_015283428.2).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-10 stage 10
Neural Plate/Tube Somites all
Entry 10 GEISHA Id Pax1.Rallis.2001 Data Source Publication Complete cDNA Template Probe show CGGGCGGAGGGTGCCGAGTCCTCTCCAGGTCCCCCCGGCGGCCGCGGGGAGCGGCCGCCGCGGCCATTTAGGAGCGGAG
Citation Rallis C, Stamataki D, Pontikakis S, Mankoo BS, Karagogeos D. Isolation of the avian homologue of the homeobox gene Mox2 and analysis of its expression pattern in developing somites and limbs. Mech Dev. 2001 Jun;104(1-2):121-4. Copyright Copyright © 2001 Elsevier Science Ireland Ltd. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (XM_015283428.2).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-18 stage 16
stage 16
stage 16
stage 16
Sclerotome Somites 25-26 stage 26
Limb Buds all
Entry 11 GEISHA Id Pax-1.Barnes.1996 Data Source Publication Complete cDNA Template Probe show CTTTCACAATTTTCCCTCCCCATCGCCTCCCTCGCGGGGCACTGACACTCTCCCCGCCCGGCCCATCGCGGCCCGGCAG
Citation Barnes GL, Hsu CW, Mariani BD, Tuan RS. Chicken Pax-1 gene: structure and expression during embryonic somite development. Differentiation. 1996 Oct;61(1):13-23. Copyright Copyright © 1996 International Society of Differentiation. Published by Elsevier Inc. Comments The complete cDNA template sequence was obtained from the information in the publication as described in Barnes et al. 1996.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-12 stage 12
stage 12
stage 12
Sclerotome Somites 13-18 stage 15
stage 18
stage 18
Sclerotome Somites all
Entry 12 Entry 13 GEISHA Id Pax1.Draga.2019 Data Source Publication Complete cDNA Template Probe show CGGGCGGAGGGTGCCGAGTCCTCTCCAGGTCCCCCCGGCGGCCGCGGGGAGCGGCCGCCGCGGCCATTTAGGAGCGGAG
Citation Margarethe Draga, Kathrin Heim, Renate Batke, Martin Wegele, Felicitas Pröls, Martin Scaal. Somite development in the avian tail. J Anat. 2019 Oct;235(4):716-724. Epub 2019 Jun 21. DOI: 10.1111/joa.13032. Copyright Copyright © 2019 Anatomical Society. Comments Authors indicated the probe was kindly provided by Bodo Christ. As insufficient information is provided in publication to verify exact sequence used to synthesize probe, above sequence was obtained from NCBI (XM_015283428.2).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-24 stage 20
stage 20
stage 20
stage 20
stage 20
stage 21
stage 21
stage 21
stage 21
stage 21
stage 22
stage 22
stage 22
stage 22
stage 22
stage 23
stage 23
stage 23
stage 23
stage 23
stage 24
stage 24
stage 24
stage 24
stage 24
Sclerotome Unlabeled 25-27 stage 25
stage 25
stage 25
stage 25
stage 25
stage 26
stage 26
stage 26
stage 26
stage 26
stage 27
stage 27
stage 27
stage 27
stage 27
Sclerotome all
Mouse Frog Fruit Fly Zebra Finch Zebrafish
