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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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RUNX2
runt related transcription factor 2

The human orthologue of this gene is associated
with the following human disease:

Cleidocranial dysplasia

Gene

Official Symbol	RUNX2
Official Full Name	runt related transcription factor 2
CGNC ID	12522
also known as	runt-related transcription factor 2\|Transcription factor RUNX2/CBFA1
gene type	protein-coding

Genomic Map

	Ensembl ID not known
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_204128
Polypeptide	NP_989459
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.157

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	860	ENSG00000124813	MIM:119600	MIM:600211
Mouse	12393	ENSMUSG00000039153	All phenotypic alleles (7):Transposon induced(1) Targeted, knock-out(3) Targeted, other(3)	MGI:99829
Xenopus	100189546, 100037059			482020
Zebrafish	405784, 405788	ENSDARG00000040261	ZDB-GENE-040629-3, ZDB-GENE-040629-4	ZFIN:ZDB-GENE-040629-3, ZFIN:ZDB-GENE-040629-4

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Links to other databases

Entrez Gene	373919
Ensembl Gene
KEGG	gga:373919

Entry 1

GEISHA Id	RUNX2.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	GCTGCGAAATGCTTCTGCTG
Reverse cDNA Template Primer	ATTAACCCTCACTAAAGGTAGGTGTGGTAGTGAGTGGTTGCG	cDNA Template Length	696
Forward cDNA Template Probe	show ATGCCTGAAGGTGACGGGCGGGTGTTATAGGTTAAAGGTGGCTGGAATAGTGCATTCGTGGGTTGGANAACCGGCTCTC AGTGAGGGATGAAATGCTTGTGAACTGCCTGGGATCTGAAAATGGGCCCAGCTCGGAAGCACCTGANAGGCGTCGGGGC ACGTCGGTGATGGCTGGAAGTCCTGTGCCTCGGGTGGAGGACAGGGGAGTCGTGGAGTGAATGGACGGCNAANTCATCT GGCTCAAGTAGGACGGGTACNACTGATCATAGGACCACGGCGGGGANGACTGCGCCTGCCTGGGGTNTNTNNTCTCNCT CTGNCCTTNTGCATTAAAATNACTTGNTNCATAGTTCATAGAGNCNNGTGGGCTNTNTGTCNGGACCCNTANTCTCATA CTGNNATNANNCAATGCTCCCTANCATCACTGAGGCNTTCAGGGTAACAAACTACNGTTTANAGTCATCNNTCTTCTGT CTGTACCTTCTTGGCTCCATCGGCCCATCCACCGTCACCTTTATGGCTCTGTGGTATGTANCGACTTGGGGGGGATTTG TCAGGACANTTATTGTCAAANTAAANCTCTTCCCTCTGCCACTCCTGCCCACNAATCNCANGTCATTGAATCTGGCCAC CTGNTTCTTCATCACANCANAANCATTTC

Stage

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Location (click to highlight)

Comments (click to highlight)

4-6

stage 5

Unlabeled

7-12

stage 8

stage 10

stage 11

Anterior Intestinal Portal
Head Mesenchyme
Notochord
Pharynx
Unlabeled

13-18

stage 14

Foregut

19-24

stage 22

stage 24

Leg Mesenchyme
Pharyngeal Arches and Clefts
Sclerotome
Somatic Mesoderm
Splanchnic Mesoderm
Wing Mesenchyme

dorsal mesentery

25-26

stage 26

Aorta
Facial Muscles
Leg Mesenchyme
Pharyngeal Arches and Clefts
Sclerotome
Somatic Mesoderm
Wing Mesenchyme

Entry 2

GEISHA Id	Runx2.Holleville.2007	Data Source	Publication
Complete cDNA Template Probe	show ATGGCATCAAACAGCCTCTTCAGCTCCGTGACACCATGTCAGCAAAACTTCTTTTGGGATCCCAGCACCAGCCGGAGGT TCAGCCCCCCCTCCAGCAGCCTGCAGCCCGGCAAGATGAGCGAGGTCAGCCCGGTCGTAGTGGCCCAACAGCAGCAGCA GCAGCAACAGCAACAGCAGCAAGAAGCCGCCGTGCCCCGGCTGCGGCCGCACGATAACCGCACCATGGTGGAGATCATC GCCGACCACCCGGCCGAGTTGGTCCGCACCGACAGCCCCAACTTCCTGTGCTCCGTGCTGCCCTCGCACTGGCGCTGCA ATAAGACCCTCCCGGTGGCCTTCAAGGTGGTGGCCTTAGGAGAAGTGCCCGATGGGACCGTGGTCACCGTGATGGCTGG GAACGACGAGAACTACTCCGCGGAGCTGCGAAATGCTTCTGCTGTGATGAAGAACCAGGTGGCCAGATTCAATGACCTG CGATTCGTGGGCAGGAGTGGCAGAGGGAAGAGCTTTACTTTGACAATAACTGTCCTGACAAATCCCCCCCAAGTCGCTA CATACCACAGAGCCATAAAGGTGACGGTGGATGGGCCGAGGGAGCCAAGAAGGCACAGACAGAAGCTTGATGACTCTAA ACCTAGTTTGTTCCCTGAACGCCTCAGTGATTTAGGGCGCATTCCTCATCCCAGTATGAGAGTAGGGGTCCCGACCCAG AGCCCACGGCCCTCTCTGAACTCTGCACCAAGTCCTTTTAATCCACAAGGACAGAGTCAGATTACAGACCCCAGGCAGG CGCAGTCGTCCCCGCCGTGGTCCTATGATCAGTCGTACCCGTCCTACTTGAGCCAGATGACTTCGCCGTCCATTCACTC CACGACTCCCCTGTCCTCCACCCGAGGCACAGGACTTCCAGCCATCACCGACGTGCCCCGACGCCTCTCAGGTGCTTCC GAGCTGGGCCCATTTTCAGATCCCAGGCAGTTCACAAGCATTTCATCCCTCACTGAGAGCCGCTTCTCCAACCCACGAA TGCACTATCCAGCCACCTTTACCTATACACCGCCCGTCACCTCAGGCATGTCACTGGGTATGTCCGCAACCACTCACTA CCACACCTACCTGCCACCACCCTACCCCGGCTCCTCCCAAAACCAAAGTGGACCTTTCCAGACCAGCAGCACTCCATAT CTCTACTATGGCACTTCGTCGGGATCGTACCAGTTCCCCATGGTGCCGGGAGGGGACCGCTCCCCTTCCAGGATGCTTC CTCCGTGCACCACCACGTCCAACGGCAGCACGCTGCTAAACCCAAACTTGCCCAACCAGAGTGACGGTGTGGAGGCGGA TGGCAGCCACAGCAGCTCCCCAACTGTTTTGAATTCTAGTGGCAGGATGGATGAGTCCGTTTGGAGGCCGTACTGAG
Citation	Holleville N, Matéos S, Bontoux M, Bollerot K, Monsoro-Burq AH. Dlx5 drives Runx2 expression and osteogenic differentiation in developing cranial suture mesenchyme. Dev Biol. 2007 Apr 15;304(2):860-74.
Copyright	Reprinted with permission from Elsevier. Copyright © 2007 Elsevier B.V. All rights reserved.
Comments	Authors said: "Chick Runx2 gene was cloned from E22.5 chick embryo RNA ...using specific primers: 5′-ATGCGTATCCCCGTAGATRCCAGC-3′ and 5′-TCAGTAKGGCCKCCANACVGC-3′." The probe sequence could not be identified within NM_204128.1. The sequence shown is from NM_204128.1

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