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Human Disease Gene Search
SPRY2 Gene Summary Expression Transcript Levels Other Species Expression JBrowse Gene Official Symbol SPRY2 Official Full Name sprouty RTK signaling antagonist 2 CGNC ID 49386 also known as protein sprouty homolog 2|sprouty 2|sprouty homolog 2|spry-2 gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Gene Ontology Links to other databases
Entry 1 GEISHA Id SPRY2.UApcr Data Source GEISHA ISH Analysis Forward cDNA Template Primer TTATAAAAGCTTGCGGCCGCAGAATATCTGCTCCAACGATGATGAGGAC Reverse cDNA Template Primer GCTCTAGAAATTAACCCTCACTAAAGGAGGGGTGACACTTGTAAGATGCC cDNA Template Length 1013 Complete cDNA Template Probe show TTTTTTTAAAAAAAGGCGGGCCGCAGAATTTTGGCCCCAACGAAGAGGGGAAACTGCGCTGACAACCCCTGCTCTTGCA
Entry 2 GEISHA Id Sprouty2.Chambers.2000 Data Source Publication Complete cDNA Template Probe show TTTTTTTTTTTTTTTTTTTTTGCTTTAGGGCTGGATTTATTTGCAAACCGCAGGAAGAAGAAAATACAACAGAGAGAGG
Citation Chambers, D., Mason, I., 2000. Expression of sprouty2 during early development of the chick embryo is coincident with known sites of FGF signalling. Mech. Dev. 91, 361-364. Copyright Mechanisms of Development 2000 Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_204800).
Entry 3 GEISHA Id Spry2.Goodnough.2007 Data Source Publication Complete cDNA Template Probe show TTTTTTTTTTTTTTTTTTTTTGCTTTAGGGCTGGATTTATTTGCAAACCGCAGGAAGAAGAAAATACAACAGAGAGAGG
Citation Goodnough LH, Brugmann SA, Hu D, Helms JA. Stage-dependent craniofacial defects resulting from Sprouty2 overexpression. Dev Dyn. 2007 Jul;236(7):1918-28. Copyright Copyright © 2007 Wiley-Liss, Inc. Comments Authors said: Templates for the relevant mRNAs for in situ hybridization were amplified from embryonic mouse cDNA by polymerase chain reaction. Thus, insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI for chick (NM_204800) although a mouse probe was used.
Entry 4 GEISHA Id Spy2.Brent.2004 Data Source Publication Complete cDNA Template Probe show TTTTTTTTTTTTTTTTTTTTTGCTTTAGGGCTGGATTTATTTGCAAACCGCAGGAAGAAGAAAATACAACAGAGAGAGG
Citation Brent AE, Tabin CJ. FGF acts directly on the somitic tendon progenitors through the Ets transcription factors Pea3 and Erm to regulate scleraxis expression. Development. 2004 Aug;131(16):3885-96. Epub 2004 Jul 14. Copyright This material is protected by copyright. The Company of Biologists' (publishers of Development) hold an Exclusive License obtained from the authors, who retain copyright. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc # NM_204800.1)
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-20 stage 20
stage 20
Dermomyotome
Entry 5 GEISHA Id SPROUTY.Blentic.2008 Data Source Publication Complete cDNA Template Probe show TTTTTTTTTTTTTTTTTTTTTGCTTTAGGGCTGGATTTATTTGCAAACCGCAGGAAGAAGAAAATACAACAGAGAGAGG
Citation Blentic A, Tandon P, Payton S, Walshe J, Carney T, Kelsh RN, Mason I, Graham A. The emergence of ectomesenchyme. Dev Dyn. 2008 Mar;237(3):592-601. Copyright Copyright © 2008 John Wiley & Sons, Inc. All Rights Reserved. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204800).
Entry 6 GEISHA Id SPRY2.Blentic.2008 Data Source Publication Complete cDNA Template Probe show TTTTTTTTTTTTTTTTTTTTTGCTTTAGGGCTGGATTTATTTGCAAACCGCAGGAAGAAGAAAATACAACAGAGAGAGG
Citation Blentic A, Tandon P, Payton S, Walshe J, Carney T, Kelsh RN, Mason I, Graham A. The emergence of ectomesenchyme. Dev Dyn. 2008 Mar;237(3):592-601. Copyright Copyright © 2008 John Wiley & Sons, Inc. All Rights Reserved.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-11 stage 11
stage 11
Isthmus/MHB Telencephalon
Entry 7 GEISHA Id SPRY2.Moura.2011 Data Source Publication Complete cDNA Template Probe show TTTTTTTTTTTTTTTTTTTTTGCTTTAGGGCTGGATTTATTTGCAAACCGCAGGAAGAAGAAAATACAACAGAGAGAGG
Citation Moura RS, Coutinho-Borges JP, Pacheco AP, Damota PO, Correia-Pinto J. FGF signaling pathway in the developing chick lung: expression and inhibition studies. PLoS One. 2011 Mar 11;6(3):e17660. Copyright PLoS One is an open access journal Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_204800).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-24 stage 24
stage 24
Lung 25-29 stage 27
stage 27
stage 27
stage 29
Lung
Entry 8 GEISHA Id SPROUTY2.Chambers.2006 Data Source Publication Complete cDNA Template Probe show TTTTTTTTTTTTTTTTTTTTTGCTTTAGGGCTGGATTTATTTGCAAACCGCAGGAAGAAGAAAATACAACAGAGAGAGG
Citation Chambers, D, Mason, I, A high throughput messenger RNA differential display screen identifies discrete domains of gene expression and novel patterning processes along the developing neural tube. BMC Dev Biol. 2006; 6: 9. Published online 2006 February 24. Copyright Copyright © 2006 Chambers and Mason; licensee BioMed Central Ltd.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Comments Authors indicated probe was 700nt. As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204800).
Entry 9 GEISHA Id SPRY2.Kuracha.2011 Data Source GEISHA ISH Analysis Complete cDNA Template Probe show TTTTTTTTTTTTTTTTTTTTTGCTTTAGGGCTGGATTTATTTGCAAACCGCAGGAAGAAGAAAATACAACAGAGAGAGG
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 31-38 stage 35
stage 36
stage 37
stage 38
stage 38
Lens
Entry 10 GEISHA Id SPROUTY2.Sabado.2012 Data Source Publication Complete cDNA Template Probe show TTTTTTTTTTTTTTTTTTTTTGCTTTAGGGCTGGATTTATTTGCAAACCGCAGGAAGAAGAAAATACAACAGAGAGAGG
Citation Sabado V, Barraud P, Baker CV, Streit A. Specification of GnRH-1 neurons by antagonistic FGF and retinoic acid signaling. Dev Biol. 2012 Feb 15;362(2):254-62.
Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (Acc. # NM_204800.1).
no images
Entry 11 GEISHA Id SPRY2.Anderson.2019 Data Source Publication Complete cDNA Template Probe show CCGCCTGAAGCCGCGGGGCTCCGCGTCCCACCTGCTGCGCTCCCGCTGCGCGCCCGGATGCAGCCGCGCCGGGGGACGT
Citation Anderson C, Hill B, Lu HC, Moverley A, Yang Y, Oliveira NMM, Baldock RA, Stern CD. A 3D molecular atlas of the chick embryonic heart. Dev Biol. 2019 Dec 1;456(1):40-46. doi: 10.1016/j.ydbio.2019.07.003. Epub 2019 Jul 5. Copyright Copyright © 2019 Elsevier Inc. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_001397684 ).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-12 stage 12
stage 12
Heart Outflow Tract
Data from NCBI Unigene EST ProfileGga.3374
Mouse Frog Fruit Fly Zebra Finch Zebrafish
