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SIX3 Gene Summary Expression Transcript Levels Other Species Expression JBrowse Gene Official Symbol SIX3 Official Full Name SIX homeobox 3 CGNC ID 49119 also known as CSIX3, homeobox protein SIX3|sine oculis homeobox homolog 3 gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Entrez Gene Ensembl Gene Genetic Phenotypes MOD Fruit Fly Human Mouse Xenopus Zebrafish
Gene Ontology Links to other databases
Entry 1 GEISHA Id SIX3.UApcr Data Source GEISHA ISH Analysis Forward cDNA Template Primer CCCATTTCTTCCTGCCCAAC Reverse cDNA Template Primer AATTAACCCTCACTAAAGTGCTGGAGCCTGTTTTTAGCC cDNA Template Length 727 Forward cDNA Template Probe show TCCTGTAAAGGTCCTGCCGGTTCCGCACCCGCTGGACGCTGCAAGTCCTCTCCTTGAAGCAATGCGTCTTCTGCTCACC
Entry 2 GEISHA Id Six3.Chapman.2002 Data Source Publication Complete cDNA Template Probe show GGCGGCGCGGGGCCGGGCGCGTGTGACGCGTGAGTGTGTGCGTGAGTGTGTGCGCGTGTGTGTGCGTGCGTGTGCCCCG
Citation Chapman SC, Schubert FR, Schoenwolf GC, Lumsden A. Analysis of spatial and temporal gene expression patterns in blastula and gastrula stage chick embryos. Dev Biol. 2002 May 1;245(1):187-99. Copyright 2002 Elsevier Science (USA). All rights reserved. Comments No mapping for this gene on the present genome build
Entry 3 GEISHA Id Six3.Ohuchi.2007 Data Source Publication Complete cDNA Template Probe show GGCGGCGCGGGGCCGGGCGCGTGTGACGCGTGAGTGTGTGCGTGAGTGTGTGCGCGTGTGTGTGCGTGCGTGTGCCCCG
Citation Ohuchi H, Hayashibara Y, Matsuda H, Onoi M, Mitsumori M, Tanaka M, Aoki J, Arai H, Noji S. Diversified expression patterns of autotaxin, a gene for phospholipid-generating enzyme during mouse and chicken development. Dev Dyn. 2007 Apr;236(4):1134-43. Copyright Copyright © 2007 Wiley-Liss, Inc. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204364).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-15 stage 15
Eye Telencephalon
Entry 4 GEISHA Id Six3.Abe.2006 Data Source Publication Complete cDNA Template Probe show GGCGGCGCGGGGCCGGGCGCGTGTGACGCGTGAGTGTGTGCGTGAGTGTGTGCGCGTGTGTGTGCGTGCGTGTGCCCCG
Citation Abe Y, Chen W, Huang W, Nishino M, Li YP.
CNBP regulates forebrain formation at organogenesis stage in chick embryos. Dev Biol. 2006 Jul 1;295(1):116-27. Epub 2006 Apr 19. Copyright Reprinted from Developmental Biology, 295, Yoko Abea, Wei Chena, Wei Huangc, Mizuho Nishinod and Yi-Ping Li, CNBP regulates forebrain formation at organogenesis stage in chick embryos, 116-127, Copyright 2006, with permission from Elsevier.
Copyright © 2006 Elsevier B.V. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc #NM_204364).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19 stage 19
Forebrain
Entry 5 GEISHA Id Six3.Chapman.2008 Data Source Direct Submission Complete cDNA Template Probe show GGCGGCGCGGGGCCGGGCGCGTGTGACGCGTGAGTGTGTGCGTGAGTGTGTGCGCGTGTGTGTGCGTGCGTGTGCCCCG
Comments Images Provided by Susan Chapman.
Entry 6 GEISHA Id SIX3.Halilagic.2007 Data Source Publication Complete cDNA Template Probe show GGCGGCGCGGGGCCGGGCGCGTGTGACGCGTGAGTGTGTGCGTGAGTGTGTGCGCGTGTGTGTGCGTGCGTGTGCCCCG
Citation Halilagic A, Ribes V, Ghyselinck NB, Zile MH, Dollé P, Studer M. Retinoids control anterior and dorsal properties in the developing forebrain. Dev Bio 2007 Mar 1;303(1):244-58 Copyright Reprinted with permission from Elsevier.
Copyright © 2007 Elsevier B.V. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_204364.1). Images are quail, but sequence and map shown are chick.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19 stage 19
stage 19
Eye Nasal Placode/Nerve
Entry 7 GEISHA Id SIX3.Merchan.2011 Data Source Publication Complete cDNA Template Probe show GGCGGCGCGGGGCCGGGCGCGTGTGACGCGTGAGTGTGTGCGTGAGTGTGTGCGCGTGTGTGTGCGTGCGTGTGCCCCG
Citation Merchán,P, Bardet, SM, Puelles, L, Ferran, JL, Comparison of Pretectal Genoarchitectonic Pattern between Quail and Chicken Embryos. Front Neuroanat. 2011; 5: 23. Prepublished online 2010 December 29. Published online 2011 April 5 Copyright Copyright © 2011 Merchán, Bardet, Puelles and Ferran. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc #NM_204364.1)
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-28 stage 26
stage 26
stage 26
stage 26
stage 26
stage 26
stage 28
stage 28
stage 28
stage 28
stage 28
Diencephalon Midbrain
Entry 8 GEISHA Id SIX3.Sanchez-Arrones.2012 Data Source Publication Complete cDNA Template Probe show GGCGGCGCGGGGCCGGGCGCGTGTGACGCGTGAGTGTGTGCGTGAGTGTGTGCGCGTGTGTGTGCGTGCGTGTGCCCCG
Citation Sanchez-Arrones L, Stern CD, Bovolenta P, Puelles L.
Sharpening of the anterior neural border in the chick by rostral endoderm signaling. Development. 2012 Mar;139(5):1034-44.
Copyright Published by The Company of Biologists © 2012. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (Acc. # NM_204364.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 4-6 stage 4
stage 4
stage 5
stage 6
stage 6
Epiblast Neural Plate/Tube
Entry 9 GEISHA Id SIX3.Reza.2007 Data Source Publication Complete cDNA Template Probe show GGCGGCGCGGGGCCGGGCGCGTGTGACGCGTGAGTGTGTGCGTGAGTGTGTGCGCGTGTGTGTGCGTGCGTGTGCCCCG
Citation Reza HM, Urano A, Shimada N, Yasuda K. Sequential and combinatorial roles of maf family genes define proper lens development. Mol Vis. 2007 Jan 16;13:18-30. Copyright This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_204364.1
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-16 stage 16
stage 16
Eye
Entry 10 GEISHA Id Six3.Reza.2002 Data Source Publication Complete cDNA Template Probe show GGCGGCGCGGGGCCGGGCGCGTGTGACGCGTGAGTGTGTGCGTGAGTGTGTGCGCGTGTGTGTGCGTGCGTGTGCCCCG
Citation Reza HM, Ogino H, Yasuda K. L-Maf, a downstream target of Pax6, is essential for chick lens development. Mech Dev. 2002 Aug;116(1-2):61-73. Copyright Copyright © 2002 Elsevier Science Ireland Ltd. All rights reserved. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_204364.1
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-17 stage 17
stage 17
Eye
Entry 11 GEISHA Id SIX3.Ferran.2007 Data Source Publication Complete cDNA Template Probe show GGCGGCGCGGGGCCGGGCGCGTGTGACGCGTGAGTGTGTGCGTGAGTGTGTGCGCGTGTGTGTGCGTGCGTGTGCCCCG
Citation Ferran JL, Sánchez-Arrones L, Sandoval JE, Puelles L. A model of early molecular regionalization in the chicken embryonic pretectum. J Comp Neurol. 2007 Dec 1;505(4):379-403. Copyright Copyright © 19992012 John Wiley & Sons, Inc. All Rights Reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (Acc. # NM_204364.1).
Entry 12 GEISHA Id SIX3.Hirashima.2008 Data Source Publication Complete cDNA Template Probe show GGCGGCGCGGGGCCGGGCGCGTGTGACGCGTGAGTGTGTGCGTGAGTGTGTGCGCGTGTGTGTGCGTGCGTGTGCCCCG
Citation Hirashima M, Kobayashi T, Uchikawa M, Kondoh H, Araki M. Anteroventrally localized activity in the optic vesicle plays a crucial role in the optic development. Dev Biol. 2008 May 15;317(2):620-31. doi: 10.1016/j.ydbio.2008.03.010. Epub 2008 Mar 20. Copyright Copyright © 2008 Elsevier Inc. All rights reserved. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_204364.1
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-11 stage 11
stage 11
Eye
Entry 13 GEISHA Id SIX3.Yuan.1999B Data Source Publication Complete cDNA Template Probe show GGCGGCGCGGGGCCGGGCGCGTGTGAGCGCGTGAGTGTGTGCGTGAGTGTGTGCGCGTGTGTGTGCGTGCGTGTGCCCC
Citation Yuan S, Schoenwolf GC. Reconstitution of the organizer is both sufficient and required to re-establish a fully patterned body plan in avian embryos. Development. 1999 Jun;126(11):2461-73 Copyright Great Britain © The Company of Biologists Limited 1999 Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (Acc. # NM_204364.2).
no images
Entry 14 GEISHA Id Six3.Hsieh.2002 Data Source Publication Complete cDNA Template Probe show GCAAGCTGCAGGCCATGTGGCTCGAAGCGCACTACCAGGAGGCCGAGAAGCTGCGGGGCCGCCCGCTGGGGCCGGTTGA
Citation Hsieh YW, Zhang XM, Lin E, Oliver G, Yang XJ. The homeobox gene Six3 is a potential regulator of anterior segment formation in the chick eye. Dev Biol. 2002 Aug 15;248(2):265-80. Copyright copyright © 2002 Elsevier Science (USA) Comments The complete cDNA template sequence was obtained from the information in the publication as described in Hsieh et al. 2002.
Entry 15 GEISHA Id cSix3.Bovolenta.1998 Data Source Publication Complete cDNA Template Probe show GGCGGCGCGGGGCCGGGCGCGTGTGACGCGTGAGTGTGTGCGTGAGTGTGTGCGCGTGTGTGTGCGTGCGTGTGCCCCG
Citation Bovolenta P, Mallamaci A, Puelles L, Boncinelli E. Expression pattern of cSix3, a member of the Six/sine oculis family of transcription factors. Mech Dev. 1998 Jan;70(1-2):201-3 Copyright Copyright © 1998 Elsevier Science Ireland Ltd. Comments The complete cDNA template sequence was obtained from the information as described in the publication in Bovolenta et al. 1998.
Entry 16 GEISHA Id SIX3.Trevers.2023 Data Source GEISHA ISH Analysis Complete cDNA Template Probe show GGCGGCGCGGGGCCGGGCGCGTGTGAGCGCGTGAGTGTGTGCGTGAGTGTGTGCGCGTGTGTGTGCGTGCGTGTGCCCC
Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204364 ).
Data from NCBI Unigene EST ProfileGga.291
Mouse Frog Fruit Fly Zebra Finch Zebrafish
