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SLIT1 Gene Summary Expression Transcript Levels Other Species Expression JBrowse Gene Official Symbol SLIT1 Official Full Name slit guidance ligand 1 CGNC ID 49247 also known as slit homolog 1 protein gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Gene Ontology Molecular Function Biological Process Cellular Component
Links to other databases
Entry 1 GEISHA Id Slit1.Jia.2005 Data Source Publication Complete cDNA Template Probe show GGTGGACTGCCACGGCACGGGTTTGCAGGCCATCCCCAAGAACATCCCACGGAACACCGAGCGCCTGGAACTCAACGGC
Citation Jia L, Cheng L, Raper J. Slit/Robo signaling is necessary to confine early neural crest cells to the ventral migratory pathway in the trunk. Dev Biol. 2005 Jun 15;282(2):411-21. Copyright Copyright © 2005 Elsevier Inc. All rights reserved. Comments According to the authors, "Chick cDNAs of Slit1 (a 1061-bp RT-PCR fragment
from a chick cDNA library corresponding to nt 6051665 of mSlit1, GenBank accession no. AF144627)...was used to generate digoxigenin or S35-labeled
riboprobes..." The sequence below was obtained from NCBI (AF144627) using the information provided.
Entry 2 GEISHA Id Slit1.Shiau.2008 Data Source Publication Complete cDNA Template Probe show ATGGCGGTGCCGCCCGGCGCGGCCTCGACCTCCGGAGGGGCAGCGGGGGTCCCGGCGGCTCTGCGGGCCGCCGCCTGGC
Citation Shiau CE, Lwigale PY, Das RM, Wilson SA, Bronner-Fraser M. Robo2-Slit1 dependent cell-cell interactions mediate assembly of the trigeminal ganglion. Nat Neurosci. 2008 Mar;11(3):269-76. Epub 2008 Feb 17.
Copyright Copyright © 2008, Nature Publishing Group Comments Insufficient information provided in publication to verify exact sequence to synthesize probe. Sequence below was obtained from NCBI (XM_421715).
Entry 3 GEISHA Id SLIT1.HalperinBarlev.2011 Data Source Publication Complete cDNA Template Probe show GGGGCGGCAGTGAGGAGTGCGGGCGCGCTTCGACGGGGCTGTGCCGTGCCAAACCGAGCCGCGCTCCCGGTGATGCGCA
Citation Halperin-Barlev O, Kalcheim C., Sclerotome-derived Slit1 drives directional migration and differentiation of Robo2-expressing pioneer myoblasts. Development. 2011 Jul;138(14):2935-45. Epub 2011 Jun 8. Copyright Permission from the authors and the Company of Biologists Ltd. Copyright held by the authors. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #XM_421715.3 ).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 13-17 stage 17
stage 17
stage 17
stage 17
stage 17
Sclerotome
Entry 4 GEISHA Id SLIT1.Battista.2008 Data Source Publication Complete cDNA Template Probe show GGGGCGGCAGTGAGGAGTGCGGGCGCGCTTCGACGGGGCTGTGCCGTGCCAAACCGAGCCGCGCTCCCGGTGATGCGCA
Citation Battisti AC, Fekete DM. Slits and Robos in the developing chicken inner ear. Dev Dyn. 2008 Feb;237(2):476-84. Copyright Copyright © 2008 Wiley-Liss, Inc. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # XM_421715.3).
Entry 5 Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-30 stage 27
stage 27
stage 27
Eye Lens 31-36 stage 36
stage 36
Eye Lens
Entry 6 GEISHA Id SLIT1.Giovannone.2012 Data Source Publication Complete cDNA Template Probe show GGGGCGGCAGTGAGGAGTGCGGGCGCGCTTCGACGGGGCTGTGCCGTGCCAAACCGAGCCGCGCTCCCGGTGATGCGCA
Citation Giovannone D, Reyes M, Reyes R, Correa L, Martinez D, Ra H, Gomez G, Kaiser J, Ma L, Stein MP, de Bellard ME. Slits affect the timely migration of neural crest cells via Robo receptor. Dev Dyn. 2012 Aug;241(8):1274-88. Copyright Copyright © 2012 Wiley Periodicals, Inc. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #XM_421715.3).
Entry 7 GEISHA Id SLIT1.Ratie.2013 Data Source Publication Complete cDNA Template Probe show GGGGCGGCAGTGAGGAGTGCGGGCGCGCTTCGACGGGGCTGTGCCGTGCCAAACCGAGCCGCGCTCCCGGTGATGCGCA
Citation Leslie Ratié, Michelle Ware, Frédérique Barloy-Hubler, Hélène Romé, Isabelle Gicquel, Christèle Dubourg, Véronique David and Valérie Dupé. Novel genes upregulated when NOTCH signalling is disrupted during hypothalamic development. Neural Dev. 2013 Dec 23;8:25. doi: 10.1186/1749-8104-8-25. Copyright © 2013 Ratié et al.; licensee BioMed Central Ltd. Comments The sequence below was obtained from NCBI (acc # NM_001277336.1) using the information provided in the publication as described in Ratie et al.
Entry 8 GEISHA Id Slit1.Vargesson.2001 Data Source GEISHA ISH Analysis Complete cDNA Template Probe show CGTCAGTGAACTGCACCTCACCGTCAACCAGCTGGAGTCAGTGCGGAGCGGCATGTTCCGGGGGCTGGACGGCTGAGGA
Comments The complete cDNA template sequence was obtained from the information from the publication as described in Vargesson et al. 2001.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-24 stage 20
stage 24
Leg Mesenchyme Limb Buds Somites 25-30 stage 26
stage 26
stage 28
Limb Buds 31-44 stage 32
stage 44
stage 44
stage 44
stage 44
Limb Buds
Data from NCBI Unigene EST ProfileGga.50644
Mouse Frog Fruit Fly Zebra Finch Zebrafish
