GEISHA - A Chicken Embryo Gene Expression Database
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SOX6
SRY-box 6

Gene
Official SymbolSOX6
Official Full NameSRY-box 6
CGNC ID4555
also known asSOX-6, transcription factor SOX-6|SRY (sex determining region Y)-box 6, SOX-6
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNAXM_421000
PolypeptideXP_421000
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.12785
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly43844FBgn0039938
Human55553ENSG00000110693MIM:607257
Mouse20679ENSMUSG00000051910All phenotypic alleles (7):Targeted, knock-out(1) Targeted, other(6) MGI:98368
Xenopus100144640483933
Zebrafish567154ENSDARG00000015536ZDB-GENE-081120-6ZFIN:ZDB-GENE-081120-6
Gene Ontology
Molecular Function
Biological Process
Cellular Component
Links to other databases
Entrez Gene423068
Ensembl GeneENSGALG00000006074
KEGGgga:423068

Entry 1

GEISHA IdChEST911o3Data SourceGEISHA ISH Analysis
Forward cDNA Template Probeshow
GGGGAGCTGGGGCTGATTTTCTTGTGTATTTAAGAATGTCTTCCAAGCAGGCTACCTCTCCATTTGCATGTGCAGCTGA
TGGAGAGGAAACAATGACCCAGGACTTAGCATCACGAGACAAGGAAGAGGGCAACAGTGATCAGCACGCGACCTCTCAT
CTGCCTCTACATAATGTAATGCACAACAAACCTCACTCTGAGGAGCTACCAACTCTAGTCACGACCATCCAACAAGATG
CTGAGTGGGATGGAGTCATCTCAGCCCAACACAGAATGGAATCGGAGAGTAATAAGTTATGTTCCCTATATTCCTTCCG
AAATACCTCTACCTCACCACACAAGCCTGACGAAGGAAGTCGTGACCGGAGTGAGCTAATGACCAGTGTTAATTTTGGA
ACGCCAGAATTAACACTGGTCATTAGCTCCGGGTACACCAGAAAGCCTGGCAGAAAAAGAGCGACAGCTCTCTACCATG
ATCACCCAGCTGATCAGCTTACGGGAGCAGCTCCTGGCTGCCCATGATGAACAGAAAAAGCTGGCAGCCTCACAAATTG
AAAAACAACGACAGCAAATGGATCTTGCTCGCCAACAGCAAGAACAGATTGCAAGACAACAGCAGCAACTTCTGCAACA
GCAGCACAAAATCAATCTACTGCAGCAGCAAATTCAGGTTCAGGGTCACATGCCTCCGCTCATGATCCCAATTTTTCCA
CACGACCAGCGGACACTGGCAGCGGCTGCTGCAGCCCAGCAGGGATTCCTCTTCCCCCCAGGAATAACTTACAAGCCAG
GTGATAACTACCCTGTGCAGTTCATTCCATCAACAAGGGCGCTGCTGCTGCTTCTGGAATCAGCCCCTTTACACTCCAG
CAACTGTATGCAGCTCAACTGGGCAGCATGCAAATTTCTCCGGGAGCCAAAATGCATCAACTCCACAGCCACCAAATTA
CGCAGGGGGCATCTTCACCCCTGGGATGAAAATGAGAAAAAAGGGACCCCCCGGTAACTCAGTTTAGGATAAAACCGCC
CAGCCCATGATTTTTC
Commentsno specific expression detected stages 3-10.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-12
stage 12
Neural Plate/Tube
Notochord
 
13-18
stage 15
stage 16
stage 18
Ear/Otic Placcode
Lateral Plate Mesoderm
Notochord
Pharyngeal Arches and Clefts
Somatopleure
Surface Ectoderm
 
19-24
stage 21
stage 23
stage 23
stage 23
stage 24
stage 24
Dermatome
Limb Buds
Outflow Tract
Pharyngeal Arches and Clefts
Sclerotome
Somatopleure
Spinal Cord
Surface Ectoderm
Wing Mesenchyme
floor plate

Entry 2

GEISHA IdSox6.Chimal-Monroy.2003Data SourcePublication
Complete cDNA Template Probeshow
GTTCATTCCATCAACAATGGCAGCTGCTGCTGCTTCTGGACTCAGCCCTTTACAGCTCCAGCAACTGTATGCAGCTCAG
CTGGCAAGCATGCAAGTTTCTCCTGGAGCCAAAATGCCATCTACTCCACAGCCACCAAATACAGCAGGGGCACTCTCAC
CCACTGGGATGAAAAATGAGAAGAGAGGGACCAGCCCGGTAACTCAAGTTAAGGATGAAGCAGCCCAGCCACTGAATCT
TTCAGCCCGACCCAAGACAGCTGAACCAGTCAAATCCCCAACATCTCCAACACAGAACCTCTTCCCACCTAGCAAAAGC
AGTCCAGTGACAGTGACAAACAAGAGCGGTATCCCCAGCCCCCTTGGTGGATCTCTGGGAAGAGGATCCTCTTTAGATA
TTCTTTCCAGTCTTAATTCACCTGCCCTGTTTGGGGACCAGGACACAGTAATGAAAGCCATTCAGGAGGCTCGGAAAAT
GAGAGAGCAGATCC
CitationChimal-Monroy J, Rodriguez-Leon J, Montero JA, Gañan Y, Macias D, Merino R, Hurle JM. Analysis of the molecular cascade responsible for mesodermal limb chondrogenesis: Sox genes and BMP signaling. Dev Biol. 2003 May 15;257(2):292-301.
CopyrightReprinted with permission from Elsevier. Copyright © 2003 Elsevier B.V. All rights reserved.
CommentsThe paper describes that a 460bp fragment was amplified using the following primers. Sox6: 5primer, 5-GTTCATTCCGTCAACAATGG-3, and 3primer 5-GGATCTGTTCTCGCATCTTCC-3. Upon comparison a sequence nearly identical to the 5' and RC3' primers were located. The proposed 488bp sequence is posted here.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
19-24
stage 23
stage 24
Leg Mesenchyme
 
25-30
stage 25
Leg Mesenchyme
 
31-32
stage 32
Leg Bones
 
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.12785

Mouse

EmageMGI:98368
EurexpressMGI:98368
MGI GXDMGI:98368

Frog

Xenbase483933

Fruit Fly

BDGPFBgn0039938

Zebra Finch

ZEBrASOX6

Zebrafish

ZFINZDB-GENE-081120-6
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