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SOX6
SRY-box 6

Gene

Official Symbol	SOX6
Official Full Name	SRY-box 6
CGNC ID	4555
also known as	SOX-6, transcription factor SOX-6\|SRY (sex determining region Y)-box 6, SOX-6
gene type	protein-coding

Genomic Map

Sequence Information

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.12785

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	43844			FBgn0039938
Human	55553	ENSG00000110693		MIM:607257
Mouse	20679	ENSMUSG00000051910	All phenotypic alleles (7):Targeted, knock-out(1) Targeted, other(6)	MGI:98368
Xenopus	100144640			483933
Zebrafish	567154	ENSDARG00000015536	ZDB-GENE-081120-6	ZFIN:ZDB-GENE-081120-6

Gene Ontology

Links to other databases

GEISHA Id	ChEST911o3	Data Source	GEISHA ISH Analysis
Forward cDNA Template Probe	show GGGGAGCTGGGGCTGATTTTCTTGTGTATTTAAGAATGTCTTCCAAGCAGGCTACCTCTCCATTTGCATGTGCAGCTGA TGGAGAGGAAACAATGACCCAGGACTTAGCATCACGAGACAAGGAAGAGGGCAACAGTGATCAGCACGCGACCTCTCAT CTGCCTCTACATAATGTAATGCACAACAAACCTCACTCTGAGGAGCTACCAACTCTAGTCACGACCATCCAACAAGATG CTGAGTGGGATGGAGTCATCTCAGCCCAACACAGAATGGAATCGGAGAGTAATAAGTTATGTTCCCTATATTCCTTCCG AAATACCTCTACCTCACCACACAAGCCTGACGAAGGAAGTCGTGACCGGAGTGAGCTAATGACCAGTGTTAATTTTGGA ACGCCAGAATTAACACTGGTCATTAGCTCCGGGTACACCAGAAAGCCTGGCAGAAAAAGAGCGACAGCTCTCTACCATG ATCACCCAGCTGATCAGCTTACGGGAGCAGCTCCTGGCTGCCCATGATGAACAGAAAAAGCTGGCAGCCTCACAAATTG AAAAACAACGACAGCAAATGGATCTTGCTCGCCAACAGCAAGAACAGATTGCAAGACAACAGCAGCAACTTCTGCAACA GCAGCACAAAATCAATCTACTGCAGCAGCAAATTCAGGTTCAGGGTCACATGCCTCCGCTCATGATCCCAATTTTTCCA CACGACCAGCGGACACTGGCAGCGGCTGCTGCAGCCCAGCAGGGATTCCTCTTCCCCCCAGGAATAACTTACAAGCCAG GTGATAACTACCCTGTGCAGTTCATTCCATCAACAAGGGCGCTGCTGCTGCTTCTGGAATCAGCCCCTTTACACTCCAG CAACTGTATGCAGCTCAACTGGGCAGCATGCAAATTTCTCCGGGAGCCAAAATGCATCAACTCCACAGCCACCAAATTA CGCAGGGGGCATCTTCACCCCTGGGATGAAAATGAGAAAAAAGGGACCCCCCGGTAACTCAGTTTAGGATAAAACCGCC CAGCCCATGATTTTTC
Comments	no specific expression detected stages 3-10.

Stage

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Comments (click to highlight)

7-12

stage 12

13-18

stage 15

stage 16

stage 18

19-24

stage 21

stage 23

stage 24

GEISHA Id	Sox6.Chimal-Monroy.2003	Data Source	Publication
Complete cDNA Template Probe	show `GTTCATTCCATCAACAATGGCAGCTGCTGCTGCTTCTGGACTCAGCCCTTTACAGCTCCAGCAACTGTATGCAGCTCAG CTGGCAAGCATGCAAGTTTCTCCTGGAGCCAAAATGCCATCTACTCCACAGCCACCAAATACAGCAGGGGCACTCTCAC CCACTGGGATGAAAAATGAGAAGAGAGGGACCAGCCCGGTAACTCAAGTTAAGGATGAAGCAGCCCAGCCACTGAATCT TTCAGCCCGACCCAAGACAGCTGAACCAGTCAAATCCCCAACATCTCCAACACAGAACCTCTTCCCACCTAGCAAAAGC AGTCCAGTGACAGTGACAAACAAGAGCGGTATCCCCAGCCCCCTTGGTGGATCTCTGGGAAGAGGATCCTCTTTAGATA TTCTTTCCAGTCTTAATTCACCTGCCCTGTTTGGGGACCAGGACACAGTAATGAAAGCCATTCAGGAGGCTCGGAAAAT GAGAGAGCAGATCC`
Citation	Chimal-Monroy J, Rodriguez-Leon J, Montero JA, Gañan Y, Macias D, Merino R, Hurle JM. Analysis of the molecular cascade responsible for mesodermal limb chondrogenesis: Sox genes and BMP signaling. Dev Biol. 2003 May 15;257(2):292-301.
Copyright	Reprinted with permission from Elsevier. Copyright © 2003 Elsevier B.V. All rights reserved.
Comments	The paper describes that a 460bp fragment was amplified using the following primers. Sox6: 5primer, 5-GTTCATTCCGTCAACAATGG-3, and 3primer 5-GGATCTGTTCTCGCATCTTCC-3. Upon comparison a sequence nearly identical to the 5' and RC3' primers were located. The proposed 488bp sequence is posted here.