GEISHA - A Chicken Embryo Gene Expression Database
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TGFBR2
transforming growth factor beta receptor 2

The human orthologue of this gene is associated
with the following human diseases:
Gene
Official SymbolTGFBR2
Official Full Nametransforming growth factor beta receptor 2
CGNC ID8694
also known asTGF-beta receptor type-2|TGF-beta receptor type II|TGF-beta type II receptor|TGFR-2|tbetaR-II|transforming growth factor, beta receptor II (70/80kDa)|transforming growth factor-beta receptor type II|transforming growth factor-beta type II receptor
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_205428
PolypeptideNP_990759
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.2645
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human7048ENSG00000163513MIM:190182MIM:190182
Mouse21813ENSMUSG00000032440All phenotypic alleles (10):Targeted, knock-out(4) Targeted, other(6) MGI:98729
Xenopus100487430, 373815876697
Zebrafish30739ENSDARG00000034541ZDB-GENE-980526-375ZFIN:ZDB-GENE-980526-375
Gene Ontology
Molecular FunctionATP binding, metal ion binding, protein binding, more...receptor signaling protein serine/threonine kinase activity, SMAD binding, transforming growth factor beta binding, transforming growth factor beta receptor activity, type II, type I transforming growth factor beta receptor binding
Biological Processactivation of protein kinase activity, brain development, bronchus morphogenesis, more...cardiac epithelial to mesenchymal transition, cartilage development, cell activation, cell migration, embryo development, embryonic cranial skeleton morphogenesis, embryonic hemopoiesis, eye development, gastrulation, heart development, in utero embryonic development, lens development in camera-type eye, lens fiber cell apoptotic process, lung development, lung lobe morphogenesis, mammary gland morphogenesis, mesenchymal cell differentiation, myeloid dendritic cell differentiation, negative regulation of cell adhesion, negative regulation of cell-cell adhesion, palate development, patterning of blood vessels, positive regulation of B cell tolerance induction, positive regulation of cell migration, positive regulation of epithelial cell migration, positive regulation of epithelial to mesenchymal transition, positive regulation of mesenchymal cell proliferation, positive regulation of NK T cell differentiation, positive regulation of T cell tolerance induction, positive regulation of tolerance induction to self antigen, regulation of gene expression, regulation of growth, response to cholesterol, smoothened signaling pathway, trachea formation, transforming growth factor beta receptor signaling pathway, vasculogenesis
Cellular Componentcell, external side of plasma membrane, integral component of membrane, receptor complex
Links to other databases
Entrez Gene396399
Ensembl GeneENSGALG00000011442
KEGGgga:396399
GEISHA IdTGFBR2.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template PrimerGGAAAAGAAGGAT GATGGGGG
Reverse cDNA Template PrimerAATTAA CCCTCACTAAAGGTCTCCA ACACCGTTACAGCGAGcDNA Template Length1026
Complete cDNA Template Probeshow
TTTTTAAAAAATGGCCCCGAATATGGAAAAGAAGGATGAGGGAATGTTTGTGTTCCTGGTACAGGGTGAAGAGTGCAAC
GATGTTCTTATTTTTTCTGCAGTTCCCCATAAGCCAGAGGAGAAAGATGAAATTTCCAAAGTCACAATCATAAGTCTTG
TCCCTTTATTGGTGATTTCTGTTGCTGTGATTGTTATCTTTTATGCCTACCGCACTCACAAGAAGAGGAAGCTCAACAA
GGCCTGGGAGAAGAATGTCAAGCCCAAGAAACATAAAGACTGCAGCGATGTTTGTGCTATTATGTTGGATGATGACCAC
TCAGACATCAGCTCTACCTGTGCCAACAACATCAACCACAACACAGAATTGCTGCCCATTGAACTGGACATTGTTGTTG
GCAAAGGAAGGTTTGCTGAAGTGTATAAAGCCAAATTGAAGCAAAACACATCTGAGCAGTATGAAACTGTGGCAGTAAA
GATCTTCCCCTATGAAGAATATGCCTCCTGGAAGACCGAGAAAGACATTTTTTCAGATGTAAATCTTAAGCATGAGAAC
ATCCTCCAATTCTTGACCGCAGAGGAGCGTAAGACAGATCTTGGTAAACAGTATTGGTTGATCACTGCCTTCCATGCTA
GAGGAAACTTGCAGGAATACCTCACACGGCATATTATCAGCTGGGAAGACCTCTGGAAACTGGGAGGATCCTTGGCCCG
AGGGATTGCCCATCTGCACAGTGATCATACACCTTGTGGTCGCCCTAAAACCCCTATTGTGCACAGAGACCTAAAGAGT
TCCAACATCCTGGTGAAAAATGATTTAACTTGCTGTCTCTGTGACTTTGGGTTATCCCTGAGACTGGACCCTTCTCTCT
CTGTGGATGACTTGGCCAACAGTGGTCAGGTTGGCACAGCAAGGTACATGGGCCCCTGAGGTTCTGGAGTCCAGGATGA
ACCTTGAGAACCATGGAGTCCTTTAAACAAACAGATGTGTACTCCATGGCTTTGGTCCCTCTGGGAAATGACTTCGCTG
TACGTGTTGGAAACCTTAGTGGGTATTTTAAA
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-12
stage 7
stage 9
stage 10
stage 11
stage 11
stage 12
Area Opaca
Area Pellucida
Blood Islands
Blood Vessels
Endocardium
Foregut
Head Mesenchyme
Lateral Plate Mesoderm
 
13-18
stage 14
stage 15
stage 16
stage 17
stage 17
stage 18
stage 18
Blood Islands
Blood Vessels
Endocardium
Extraembryonic Blood Vessels
Head Mesenchyme
Heart
Lateral Plate Mesoderm
Myotome
Paraxial Mesoderm
Pharyngeal Arches and Clefts
Section Completed
19-24
stage 20
stage 20
stage 20
stage 21
stage 21
stage 21
stage 22
Allantois
Blood Vessels
Endocardium
Eye
Heart
Leg
Paraxial Mesoderm
Pharyngeal Arches and Clefts
Wing
Wing Mesenchyme
Section Completed
25
stage 25
stage 25
stage 25
Allantois
Blood Vessels
Endocardium
Eye
Heart
Leg
Paraxial Mesoderm
Pharyngeal Arches and Clefts
Wing
Front.
Right side.
Section Completed
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.2645

Mouse

EmageMGI:98729
EurexpressMGI:98729
MGI GXDMGI:98729

Frog

Xenbase876697

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-980526-375
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