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NTRK1 The human orthologue of this gene is associated
Gene Summary Expression Transcript Levels Other Species Expression JBrowse Gene Official Symbol NTRK1 Official Full Name neurotrophic receptor tyrosine kinase 1 CGNC ID 49757 also known as CTRKA, trkA, high affinity nerve growth factor receptor|neurotrophic tyrosine kinase, receptor, type 1|trk-A|tropomyosin receptor kinase gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Gene Ontology Molecular Function ATP binding , nerve growth factor binding , nerve growth factor receptor activity , more... protein homodimerization activity , transmembrane receptor protein tyrosine kinase activity Biological Process axonogenesis involved in innervation , negative regulation of cell proliferation , more... negative regulation of neuron apoptotic process , nerve growth factor signaling pathway , neurotrophin TRK receptor signaling pathway , peptidyl-tyrosine phosphorylation , positive regulation of ERK1 and ERK2 cascade , positive regulation of neuron projection development , positive regulation of NF-kappaB transcription factor activity , positive regulation of Ras GTPase activity , positive regulation of Ras protein signal transduction , protein autophosphorylation , protein phosphorylation , sympathetic nervous system development Cellular Component early endosome membrane , integral component of plasma membrane , late endosome membrane
Links to other databases
Entry 1 GEISHA Id TRKA.Yang.2010 Data Source Publication Complete cDNA Template Probe show GATGCTTTCCAGGACAACCACAGGCTGAGCCATGTGAATCTCTCCTTCAATGCGTTGACCAGCCTGTCCTGGAAAACCT
Citation Yang M, Cagle MC, Honig MG. Identification of cerebellin2 in chick and its preferential expression by subsets of developing sensory neurons and their targets in the dorsal horn. J Comp Neurol. 2010 Jul 15;518(14):2818-40.
Copyright Copyright © 2010 Wiley-Liss, Inc. Comments The cDNA template used to generate the probe was obtained by PCR as described in Yang et al.
Entry 2 GEISHA Id TRKA.Apostolova.2007 Data Source Publication Complete cDNA Template Probe show TGCGATGCTGCCCGCCTGGCTCCGGCTGTGCCTGGCTGCGCTGCTGCTGCCCCCGGGAGCCGCCGTTCCTCCCGCCTGC
Citation Apostolova G, Dorn R, Ka S, Hallböök F, Lundeberg J, Liser K, Hakim V, Brodski C, Michaelidis TM, Dechant G. Neurotransmitter phenotype-specific expression changes in developing sympathetic neurons. Mol Cell Neurosci. 2007 Jul;35(3):397-408. Epub 2007 Apr 1. Copyright Copyright © 2007 Elsevier Inc. All rights reserved. Comments
As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_205378.1
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 31-44 stage 44
stage 44
Spinal Ganglia and Nerves
Entry 3 GEISHA Id TRKA.Karlsson.1998 Data Source GEISHA ISH Analysis Complete cDNA Template Probe show TGCGATGCTGCCCGCCTGGCTCCGGCTGTGCCTGGCTGCGCTGCTGCTGCCCCCGGGAGCCGCCGTTCCTCCCGCCTGC
Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence was obtained from NCBI (NM_205378.1). Also known as: trkA; CTRKA
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 31-44 stage 35
stage 35
stage 41
stage 44
Retina
Data from NCBI Unigene EST ProfileGga.579
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