GEISHA - A Chicken Embryo Gene Expression Database
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TTR
transthyretin

The human orthologue of this gene is associated
with the following human diseases:
Gene
Official SymbolTTR
Official Full Nametransthyretin
CGNC ID
also known astransthyretin|TBPA|prealbumin, Transthyretin, Prealbumin, Ttr, TBPA
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_205335
PolypeptideNP_990666
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.2620
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human7276ENSG00000118271MIM:176300MIM:176300
Mouse22139ENSMUSG00000061808All phenotypic alleles (7):Targeted, knock-out(2) Targeted, other(5) MGI:98865
Xenopus100125183, 397787479394
Zebrafish449556ENSDARG00000037191ZDB-GENE-040927-14ZFIN:ZDB-GENE-040927-14
Gene Ontology
Molecular Functionbinding, hormone activity, identical protein binding, protein binding, protein domain specific binding
Biological Processoocyte growth, protein complex assembly, response to virus, transport
Cellular Componentclathrin-coated vesicle, extracellular space, macromolecular complex, yolk
Links to other databases
Entrez Gene396277
Ensembl GeneENSGALG00000015143
KEGGgga:396277

Entry 1

GEISHA IdTransthyretin.Yanai.2005Data SourcePublication
Complete cDNA Template Probeshow
CCACAACTCACTAACAGCAAACAGAATGGCCTTTCACTCTACTCTTCTTGTTTTCTTAGCTGGACTGGTATTTCTCTCC
GAAGCTGCACCACTGGTCTCCCATGGCTCTGTTGATTCCAAATGCCCTCTCATGGTGAAAGTGCTGGATGCAGTCAGAG
GAAGTCCTGCAGCTAACGTAGCTGTTAAAGTCTTTAAAAAGGCTGCAGATGGAACCTGGCAGGACTTTGCTACTGGGAA
AACCACAGAGTTCGGTGAAATCCATGAGCTCACAACAGAAGAACAGTTTGTAGAAGGAGTATACAGAGTTGAGTTTGAC
ACCAGTTCTTACTGGAAGGGACTTGGCCTTTCCCCATTCCATGAATATGCTGATGTGGTGTTCACTGCTAATGATTCTG
GCCACCGCCATTATACCATCGCTGCTCTCCTCAGTCCTTTCTCTTACTCAACAACTGCTGTTGTCAGTGATCCCCAGGA
ATGAAAACATACTGTCAATAGATATATATACCCTCCTCTGCTAGGACTATTATAGGTTTTTAGGAGGAAGGTTTTTCCG
ATTGCTAATGCATATCCTTTTGCTACATTAGTTGTTATTTGTTTTTCATTTTGTAACCTGGCAAAAATTCAGACAAGTC
AATAAAATGTAACTTCTTTAAAACAAAAAAAAAAAAAA
CitationYanai M, Tatsumi N, Endo F, Yokouchi Y. Analysis of gene expression patterns in the developing chick liver. Dev Dyn. 2005 Jul;233(3):1116-22.
CopyrightWiley-Liss, Inc. 2005
CommentsAuthors indicate probe information can be found in (Duan et al., 1991), which is unavailable online. The sequence below was obtained from NCBI (acc # NM_205335).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-12
stage 12
Anterior Intestinal Portal
Endoderm, early
Yolk Sack or Stalk
 
13-18
stage 17
Liver
Pancreas
Yolk Sack or Stalk
 
19-24
stage 22
Liver
Pancreas
Yolk Sack or Stalk
 
25-30
stage 25
stage 30
Anterior Intestinal Portal
Liver
Pancreas
 
31-42
stage 42
Liver
 

Entry 2

GEISHA IdTtr.vonFrowein.2006Data SourceGEISHA ISH Analysis
Complete cDNA Template Probeshow
CCACAACTCACTAACAGCAAACAGAATGGCCTTTCACTCTACTCTTCTTGTTTTCTTAGCTGGACTGGTATTTCTCTCC
GAAGCTGCACCACTGGTCTCCCATGGCTCTGTTGATTCCAAATGCCCTCTCATGGTGAAAGTGCTGGATGCAGTCAGAG
GAAGTCCTGCAGCTAACGTAGCTGTTAAAGTCTTTAAAAAGGCTGCAGATGGAACCTGGCAGGACTTTGCTACTGGGAA
AACCACAGAGTTCGGTGAAATCCATGAGCTCACAACAGAAGAACAGTTTGTAGAAGGAGTATACAGAGTTGAGTTTGAC
ACCAGTTCTTACTGGAAGGGACTTGGCCTTTCCCCATTCCATGAATATGCTGATGTGGTGTTCACTGCTAATGATTCTG
GCCACCGCCATTATACCATCGCTGCTCTCCTCAGTCCTTTCTCTTACTCAACAACTGCTGTTGTCAGTGATCCCCAGGA
ATGAAAACATACTGTCAATAGATATATATACCCTCCTCTGCTAGGACTATTATAGGTTTTTAGGAGGAAGGTTTTTCCG
ATTGCTAATGCATATCCTTTTGCTACATTAGTTGTTATTTGTTTTTCATTTTGTAACCTGGCAAAAATTCAGACAAGTC
AATAAAATGTAACTTCTTTAAAACAAAAAAAAAAAAAA
CommentsAuthors said: Plasmid templates were used to generate digoxygenin antisense riboprobes: Ttr (M. Wassef) (Duan et al., 1991). As information provided was insufficient to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_205335).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
25-28
stage 28
 choroid plexus

Entry 3

GEISHA IdTTR.Barron.1998Data SourcePublication
Complete cDNA Template Probeshow
TTCTCTCCGAAGCTGCACCACTGGTCTCCCATGGCTCTGTTGATTCCAAATGCCCTCTCATGGTGAAAGTGCTGGATGC
AGTCAGAGGAAGTCCTGCAGCTAACGTAGCTGTTAAAGTCTTTAAAAAGGCTGCAGATGGAACCTGGCAGGACTTTGCT
ACTGGGAAAACCACAGAGTTTGGTGAAATCCATGAGCTCACAACAGAAGAACAGTTTGTAGAAGGAGTATACAGAGTTG
AGTTTGACACCAGTTCTTACTGGAAGGGACTTGGCCTTTCCCCATTCCATGAATATGCTGATGTGGTGTTCACTGCTAA
TGATTCTGGCCACCGCCATTATACCATCGCTGCTCTCCTCAGTCCT
CitationBarron M, McAllister D, Smith SM, Lough J. Expression of retinol binding protein and transthyretin during early embryogenesis. Dev Dyn. 1998 Jul;212(3):413-22.
CopyrightCopyright © 1998 Wiley‐Liss, Inc.
CommentsThe complete cDNA template sequence was obtained from the information from the publication as described in Barron al. 1998.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 6
Endoderm
 
7-12
stage 7
stage 8
stage 9
stage 10
Endoderm
 
13-18
stage 14
stage 14
stage 14
Endoderm
Endothelial Cells
Foregut
Myocardium
 
31-44
stage 44
stage 44
stage 44
  

Entry 4

GEISHA IdTTR.Anderson.2019Data SourcePublication
Complete cDNA Template Probeshow
CCACAACTCACTAACAGCAAACAGAATGGCCTTTCACTCTACTCTTCTTGTTTTCTTAGCTGGACTGGTATTTCTCTCC
GAAGCTGCACCACTGGTCTCCCATGGCTCTGTTGATTCCAAATGCCCTCTCATGGTGAAAGTGCTGGATGCAGTCAGAG
GAAGTCCTGCAGCTAACGTAGCTGTTAAAGTCTTTAAAAAGGCTGCAGATGGAACCTGGCAGGACTTTGCTACTGGGAA
AACCACAGAGTTTGGTGAAATCCATGAGCTCACAACAGAAGAACAGTTTGTAGAAGGAGTATACAGAGTTGAGTTTGAC
ACCAGTTCTTACTGGAAGGGACTTGGCCTTTCCCCATTCCATGAATATGCTGATGTGGTGTTCACTGCTAATGATTCTG
GCCACCGCCATTATACCATCGCTGCTCTCCTCAGTCCTTTCTCTTACTCAACAACTGCTGTTGTCAGTGATCCCCAGGA
ATGAAAACATACTGTCAATAGATATATATACCCTCCTCTGCTAGGACTATTATAGGTTTTTAGGAGGAAGGTTTTTCCG
ATTGCTAATGCATATCCTTTTGCTACATTAGTTGTTATTTGTTTTTCATTTTGTAACCTGGCAAAAATTCAGATAAGTC
AATAAAATGTAACTTCTTTAAAACATAAAAA
CitationAnderson C, Hill B, Lu HC, Moverley A, Yang Y, Oliveira NMM, Baldock RA, Stern CD. A 3D molecular atlas of the chick embryonic heart. Dev Biol. 2019 Dec 1;456(1):40-46. doi: 10.1016/j.ydbio.2019.07.003. Epub 2019 Jul 5.
CopyrightCopyright © 2019 Elsevier Inc. All rights reserved.
CommentsThe complete cDNA template sequence was obtained from the information from the publication as described in Anderson et al. 2019.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-12
stage 12
Heart
 
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.2620

Mouse

EmageMGI:98865
EurexpressMGI:98865
MGI GXDMGI:98865

Frog

Xenbase479394

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-040927-14
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