GEISHA - A Chicken Embryo Gene Expression Database
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TNNT2
troponin T2, cardiac type

The human orthologue of this gene is associated
with the following human diseases:
Gene
Official SymbolTNNT2
Official Full Nametroponin T2, cardiac type
CGNC ID176
also known astroponin T, cardiac muscle isoforms|cardiac troponin T form I|tnTC|troponin T type 2 (cardiac), Troponin T, cardiac muscle isoforms , cardiac Troponin T, cTNT, TnTC
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_205449
PolypeptideNP_990780
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.4984
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human7139ENSG00000118194MIM:115195MIM:191045
Mouse21956ENSMUSG00000026414All phenotypic alleles (3):Targeted, knock-out(2) Targeted, other(1) MGI:104597
Xenopus100493699, 398518482613
Zebrafish58071ENSDARG00000020610ZDB-GENE-000626-1, ZDB-GENE-091106-2ZFIN:ZDB-GENE-000626-1, ZFIN:ZDB-GENE-091106-2
Gene Ontology
Molecular Function
Biological Processregulation of muscle contraction
Cellular Componenttroponin complex
Links to other databases
Entrez Gene396433
Ensembl Gene
KEGGgga:396433

Entry 1

GEISHA IdcTNTData SourceGEISHA ISH Analysis
Complete cDNA Template Probeshow
TTCCCAGATAGCCGCCGGCACCCACCGCTCCGTGGGACCTCGGCACAGGTAGCCAAGCATGTCGGACTCTGAAGAGGTC
GTTGAGGAATACGAGCAGGAGCAGGAAGAGGAGTATGTGGAAGAAGAAGAGGAAGAATGGCTTGAGGAAGACGACGGTC
AGGAGGATCAGGTAGACGAGGAGGAAGAGGAGACAGAGGAAACCACGGCAGAAGAACAAGAAGATGAAACAAAAGCACC
AGGAGAAGGTGGTGAGGGGGACCGGGAGCAGGAGCCTGGGGAAGGTGAATCAAAGCCCAAACCCAAGCCCTTCATGCCC
AACCTGGTGCCTCCCAAAATCCCTGATGGCGAGCGCCTGGATTTCGATGACATCCACCGCAAGCGCATGGAGAAGGACC
TGAATGAGCTGCAGGCCCTCATCGAAGCCCATTTTGAGAGCAGGAAGAAGGAGGAAGAGGAGCTCATCTCTCTCAAGGA
CAGGATTGAGCAGCGGAGGGCAGAGAGGGCAGAGCAGCAGCGCATCCGCAGCGAGAGGGAGAAGGAGCGCCAGGCCCGC
ATGGCTGAGGAGAGAGCTCGCAAAGAGGAAGAGGAGGCACGGAAGAAGGCTGAGAAAGAAGCTCGGAAAAAGAAAGCTT
TCTCCAACATGCTGCACTTTGGAGGCTACATGCAGAAGTCGGAGAAGAAGGGTGGCAAGAAGCAAACGGAGCGGGAGAA
GAAGAAAAAGATCCTCAGCGAGCGGCGGAAGCCTCTGAACATCGACCACCTCAGCGAAGACAAACTGAGGGACAAAGCC
AAGGAGCTGTGGCAAACCATCCGTGACCTGGAGGCTGAGAAATTTGACTTGCAGGAGAAGTTCAAGCGGCAGAAGTACG
AGATCAACGTCCTTCGAAATCGTGTCAGTGACCACCAGAAGGTCAAAGGGTCAAAGGCTGCCCGTGGGAAGACCATGGT
GGGCGGCCGGTGGAAGTAGATGGCTCTGAAGGCAAAGGTGAGGCTCAGCCATCAGATGCAGTGCTGTGCGCTCAACCTA
TGCCAGGGCTCTGCTGCCTCCCCACCATGCAGTGCTTGTACAGTGCTTGCTGCTGGCTCCACGCTGCCGGGGTGGGCAG
GTGCTCAGCGAGGCGCTGATTCTCATCTCCACACCCCCACATGATGTTGTGTCTGTAAATAAAGAGAGGAGTGAGGGGG
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 4
stage 4
stage 5
stage 5
stage 5
stage 6
Cardiovascular
Early Mesoderm
Splanchnic Mesoderm
heart field
rudiment
7-12
stage 7
stage 7
stage 8
stage 9
stage 10
stage 11
stage 12
stage 12
stage 12
Cardiovascular
Extraembryonic
Heart
Heart Tube
Splanchnic Mesoderm
precardiac region
13-18
stage 13
stage 13
stage 13
stage 14
stage 16
Atria
Heart Tube
Myocardium
Myotome
Outflow Tract
Sinus Venosus
Splanchnic Mesoderm
Ventricles
 
19-20
stage 20
stage 20
Myocardium
Myotome
 

Entry 2

GEISHA IdTroponinT.Salle.2004Data SourcePublication
Complete cDNA Template Probeshow
TTCCCAGATAGCCGCCGGCACCCACCGCTCCGTGGGACCTCGGCACAGGTAGCCAAGCATGTCGGACTCTGAAGAGGTC
GTTGAGGAATACGAGCAGGAGCAGGAAGAGGAGTATGTGGAAGAAGAAGAGGAAGAATGGCTTGAGGAAGACGACGGTC
AGGAGGATCAGGTAGACGAGGAGGAAGAGGAGACAGAGGAAACCACGGCAGAAGAACAAGAAGATGAAACAAAAGCACC
AGGAGAAGGTGGTGAGGGGGACCGGGAGCAGGAGCCTGGGGAAGGTGAATCAAAGCCCAAACCCAAGCCCTTCATGCCC
AACCTGGTGCCTCCCAAAATCCCTGATGGCGAGCGCCTGGATTTCGATGACATCCACCGCAAGCGCATGGAGAAGGACC
TGAATGAGCTGCAGGCCCTCATCGAAGCCCATTTTGAGAGCAGGAAGAAGGAGGAAGAGGAGCTCATCTCTCTCAAGGA
CAGGATTGAGCAGCGGAGGGCAGAGAGGGCAGAGCAGCAGCGCATCCGCAGCGAGAGGGAGAAGGAGCGCCAGGCCCGC
ATGGCTGAGGAGAGAGCTCGCAAAGAGGAAGAGGAGGCACGGAAGAAGGCTGAGAAAGAAGCTCGGAAAAAGAAAGCTT
TCTCCAACATGCTGCACTTTGGAGGCTACATGCAGAAGTCGGAGAAGAAGGGTGGCAAGAAGCAAACGGAGCGGGAGAA
GAAGAAAAAGATCCTCAGCGAGCGGCGGAAGCCTCTGAACATCGACCACCTCAGCGAAGACAAACTGAGGGACAAAGCC
AAGGAGCTGTGGCAAACCATCCGTGACCTGGAGGCTGAGAAATTTGACTTGCAGGAGAAGTTCAAGCGGCAGAAGTACG
AGATCAACGTCCTTCGAAATCGTGTCAGTGACCACCAGAAGGTCAAAGGGTCAAAGGCTGCCCGTGGGAAGACCATGGT
GGGCGGCCGGTGGAAGTAGATGGCTCTGAAGGCAAAGGTGAGGCTCAGCCATCAGATGCAGTGCTGTGCGCTCAACCTA
TGCCAGGGCTCTGCTGCCTCCCCACCATGCAGTGCTTGTACAGTGCTTGCTGCTGGCTCCACGCTGCCGGGGTGGGCAG
GTGCTCAGCGAGGCGCTGATTCTCATCTCCACACCCCCACATGATGTTGTGTCTGTAAATAAAGAGAGGAGTGAGGGGG
CitationSallee D, Qiu Y, Liu J, Watanabe M, Fisher SA. Fas ligand gene transfer to the embryonic heart induces programmed cell death and outflow tract defects. Dev Biol. 2004 Mar 15;267(2):309-19.
CopyrightCopyright © 2004 Elsevier Inc. All rights reserved.
CommentsInsufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205449).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
25-30
stage 30
Heart
Myocardium
 

Entry 3

GEISHA IdCTNT.Darnell.2010Data SourcePublication
Complete cDNA Template Probeshow
TTCCCAGATAGCCGCCGGCACCCACCGCTCCGTGGGACCTCGGCACAGGTAGCCAAGCATGTCGGACTCTGAAGAGGTC
GTTGAGGAATACGAGCAGGAGCAGGAAGAGGAGTATGTGGAAGAAGAAGAGGAAGAATGGCTTGAGGAAGACGACGGTC
AGGAGGATCAGGTAGACGAGGAGGAAGAGGAGACAGAGGAAACCACGGCAGAAGAACAAGAAGATGAAACAAAAGCACC
AGGAGAAGGTGGTGAGGGGGACCGGGAGCAGGAGCCTGGGGAAGGTGAATCAAAGCCCAAACCCAAGCCCTTCATGCCC
AACCTGGTGCCTCCCAAAATCCCTGATGGCGAGCGCCTGGATTTCGATGACATCCACCGCAAGCGCATGGAGAAGGACC
TGAATGAGCTGCAGGCCCTCATCGAAGCCCATTTTGAGAGCAGGAAGAAGGAGGAAGAGGAGCTCATCTCTCTCAAGGA
CAGGATTGAGCAGCGGAGGGCAGAGAGGGCAGAGCAGCAGCGCATCCGCAGCGAGAGGGAGAAGGAGCGCCAGGCCCGC
ATGGCTGAGGAGAGAGCTCGCAAAGAGGAAGAGGAGGCACGGAAGAAGGCTGAGAAAGAAGCTCGGAAAAAGAAAGCTT
TCTCCAACATGCTGCACTTTGGAGGCTACATGCAGAAGTCGGAGAAGAAGGGTGGCAAGAAGCAAACGGAGCGGGAGAA
GAAGAAAAAGATCCTCAGCGAGCGGCGGAAGCCTCTGAACATCGACCACCTCAGCGAAGACAAACTGAGGGACAAAGCC
AAGGAGCTGTGGCAAACCATCCGTGACCTGGAGGCTGAGAAATTTGACTTGCAGGAGAAGTTCAAGCGGCAGAAGTACG
AGATCAACGTCCTTCGAAATCGTGTCAGTGACCACCAGAAGGTCAAAGGGTCAAAGGCTGCCCGTGGGAAGACCATGGT
GGGCGGCCGGTGGAAGTAGATGGCTCTGAAGGCAAAGGTGAGGCTCAGCCATCAGATGCAGTGCTGTGCGCTCAACCTA
TGCCAGGGCTCTGCTGCCTCCCCACCATGCAGTGCTTGTACAGTGCTTGCTGCTGGCTCCACGCTGCCGGGGTGGGCAG
GTGCTCAGCGAGGCGCTGATTCTCATCTCCACACCCCCACATGATGTTGTGTCTGTAAATAAAGAGAGGAGTGAGGGGG
CitationDarnell DK, Stanislaw S, Kaur S, Antin PB. Whole mount in situ hybridization detection of mRNAs using short LNA containing DNA oligonucleotide probes. RNA. 2010 March; 16(3): 632–637.
CopyrightCopyright © 2010 RNA Society
CommentsProbes were multiple LNAs whose sequences can be found at http://rnajournal.cshlp.org/content/suppl/2010/01/08/rna.1775610.DC1/Supp_figs_S1_S3.pdf. NCBI (acc #NM_205449.1) is given for reference only.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
19-24
stage 24
stage 24
Heart Tube
Somites
 

Entry 4

GEISHA IdcTNT.Antin.2002Data SourcePublication
Complete cDNA Template Probeshow
CAAACTGAGGGACAAAGCCAAGGAGCTGTGGCAAACCATCCGTGACCTGGAGGCTGAGAAATTTGACTTGCAGGAGAAG
TTCAAGCGGCAGAAGTACGAGATCAACGTCCTTCGAAATCGTGTCAGTGACCACCAGAAGGTCAAAGGGTCAAAGGCTG
CCCGTGGGAAGACCATGGTGGGCGGCCGGTGGAAGTAGATGGCTCTGAAGGCAAAGGTGAGGCTCAGCCATCAGATGCA
GTGCTGTGCGCTCAACCTATGCCAGGGCTCTGCTGCCTCCCCACCATGCAGTGCTTGTACAGTGCTTGCTGCTGGCTCC
ACGCTGCCGGGGTGGGCAGGTGCTCAGCGAGGCGCTGATTCTCATCTCCACACCCCCA
CitationAntin PB, Bales MA, Zhang W, Garriock RJ, Yatskievych TA, Bates MA. Precocious expression of cardiac troponin T in early chick embryos is independent of bone morphogenetic protein signaling. Dev Dyn. 2002 Oct;225(2):135-41.
CopyrightCopyright © 2002 Wiley‐Liss, Inc.
CommentsThe complete cDNA template sequence was obtained from information referenced in the publication as described in Antin et al. 2002. cTNT gene name is also known as TNNT2 in NCBI.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 4
stage 4
stage 5
stage 6
Early Mesoderm
Extraembryonic Mesoderm
 
7-12
stage 7
stage 7
stage 9
stage 11
Early Mesoderm
Extraembryonic Mesoderm
Heart
Lateral Plate Mesoderm
Somatic Mesoderm
Splanchnic Mesoderm
 
13-18
stage 14
Heart
 
31-44
stage 44
  
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.4984

Mouse

EmageMGI:104597
EurexpressMGI:104597
MGI GXDMGI:104597

Frog

Xenbase482613

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-000626-1, ZDB-GENE-091106-2
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