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VAX1
ventral anterior homeobox 1| Gene | | Official Symbol | VAX1 | | Official Full Name | ventral anterior homeobox 1 | | CGNC ID | 49384 | | also known as | cVAX, ventral anterior homeobox 1|Vax, Ventral anterior homeobox 1 | | gene type | protein-coding |
| | Genomic Map | | | Sequence Information | | | Gene Expression | | | Orthology | | | Gene Ontology | | Molecular Function | chromatin DNA binding, sequence-specific DNA binding transcription factor activity, more...transcription regulatory region sequence-specific DNA binding | | Biological Process | axon guidance, brain development, camera-type eye development, more...negative regulation of neuroblast proliferation, negative regulation of transcription from RNA polymerase II promoter, neuron migration, palate development, skeletal muscle cell differentiation, transcription, DNA-templated | | Cellular Component | nucleus |
| | Links to other databases | |
Entry 1| GEISHA Id | Vax.Canto-Soler.2006 | Data Source | Publication | | Complete cDNA Template Probe | show GTTGTTGCTTTTTTTGTTTTCTTTTTATTGCACTACATGTTTGGGAAACAAGACAAAATGGACGTTAGATGCAGCACAG
AGACTGAAGCCAATCGGGTCTCGAAGAACGGACACAAGGAGGGCAAGGACAGCAAAGGGGCTGAAGGAAATATCTCTAC
TTCTTTTCTGAAGGAGCAACAAGGGACTTTTTCTGCCTCCGCAGCTACCGAAGACTGTAACAAAAGTAAATCTGGTTCG
GCGGACCCGGACTACTGCAGGAGGATCCTGGTCAGAGATGCCAAAGGTTCCATCCGAGAGATCATCCTGCCCAAAGGCC
TCGATTTGGACCGTCCCAAGCGGACCCGCACCTCCTTCACGGCCGAGCAGCTCTACCGCCTGGAGATGGAGTTCCAGCG
GTGCCAGTACGTGGTGGGGCGGGAGCGCACCGAGCTGGCGCGGCAGCTCAACCTCTCCGAGACTCAGGTAAAGGTGTGG
TTCCAGAACCGACGCACCAAGCAGAAAAAGGACCAGGGCAAAGACTCGGAGCTGCGTTCGGTGGTATCCGAGACCGCCG
CCACCTGCAGCGTCCTGCGGCTGCTGGAGCAGGGCCGCCTGCTCTCCCCGCCTGGGCTGCCCGGCCTCCTTGCCGCCCT
GTGCCAGCGGAACGCTGGGCTCGGCGCTGCGGGGCCCCGGCCTCTGGCTGCGGGCAGCGGCACGGCGGCGGCGGCGGCG
GCGGCGGCGGCTCCGGCCGGGGGATCCCCGCACCCCCCGAGCGCCGGCACCGCGGCGGGGCCGCCCCCTCCGGCAGCGC
TGCACGGAACGGCCGCCGCCGCCGCCGGGCACGGGCTCTTCGGGCTGCCGGTGCCCACGCTGCTGGGCTCGGTGGCGGG
GCGGCTCTCCTCCGCGCCGCTGGCCGTGGCGGGCTCGCTGGCGGGCAACTTGCAGGAACTGTCGGCCCGCTACCTGAGC
TCGTCCGCCTTCGAGCCCTACTCCCGGACCAACAATAAAGAAAGCGCTGAGAAAAAAGCACTGGACTGAGAAAAAAGCA
CTGGACTGA | | Citation | Canto-Soler MV, Adler R. Optic cup and lens development requires Pax6 expression in the early optic vesicle during a narrow time window. Dev Biol. 2006 Jun 1;294(1):119-32. Epub 2006 Mar 27. | | Copyright | Reprinted from Developmental Biology, 294, Issue 1, M. Valeria Canto-Soler and Ruben Adler, Optic cup and lens development requires Pax6 expression in the early optic vesicle during a narrow time window, 119-132, 2006, with permission from Elsevier.
Copyright © 2006 Elsevier B.V. All rights | | Comments | Probes were generated from cDNAs generously provided by the following investigators: cVax (Constance Cepko, Harvard Medical School, Boston, MA). ." As information provided was insufficient to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204799) |
| Stage | Image (click image to view full size) | Location (click to highlight) | Comments (click to highlight) | | 7-12 |
 | | stage 11 |
| Retina
| | 13-18 |  | | stage 18 |
| Retina
|
Entry 2| GEISHA Id | VAX.Peters.2002 | Data Source | Publication | | Complete cDNA Template Probe | show GTTGTTGCTTTTTTTGTTTTCTTTTTATTGCACTACATGTTTGGGAAACAAGACAAAATGGACGTTAGATGCAGCACAG
AGACTGAAGCCAATCGGGTCTCGAAGAACGGACACAAGGAGGGCAAGGACAGCAAAGGGGCTGAAGGAAATATCTCTAC
TTCTTTTCTGAAGGAGCAACAAGGGACTTTTTCTGCCTCCGCAGCTACCGAAGACTGTAACAAAAGTAAATCTGGTTCG
GCGGACCCGGACTACTGCAGGAGGATCCTGGTCAGAGATGCCAAAGGTTCCATCCGAGAGATCATCCTGCCCAAAGGCC
TCGATTTGGACCGTCCCAAGCGGACCCGCACCTCCTTCACGGCCGAGCAGCTCTACCGCCTGGAGATGGAGTTCCAGCG
GTGCCAGTACGTGGTGGGGCGGGAGCGCACCGAGCTGGCGCGGCAGCTCAACCTCTCCGAGACTCAGGTAAAGGTGTGG
TTCCAGAACCGACGCACCAAGCAGAAAAAGGACCAGGGCAAAGACTCGGAGCTGCGTTCGGTGGTATCCGAGACCGCCG
CCACCTGCAGCGTCCTGCGGCTGCTGGAGCAGGGCCGCCTGCTCTCCCCGCCTGGGCTGCCCGGCCTCCTTGCCGCCCT
GTGCCAGCGGAACGCTGGGCTCGGCGCTGCGGGGCCCCGGCCTCTGGCTGCGGGCAGCGGCACGGCGGCGGCGGCGGCG
GCGGCGGCGGCTCCGGCCGGGGGATCCCCGCACCCCCCGAGCGCCGGCACCGCGGCGGGGCCGCCCCCTCCGGCAGCGC
TGCACGGAACGGCCGCCGCCGCCGCCGGGCACGGGCTCTTCGGGCTGCCGGTGCCCACGCTGCTGGGCTCGGTGGCGGG
GCGGCTCTCCTCCGCGCCGCTGGCCGTGGCGGGCTCGCTGGCGGGCAACTTGCAGGAACTGTCGGCCCGCTACCTGAGC
TCGTCCGCCTTCGAGCCCTACTCCCGGACCAACAATAAAGAAAGCGCTGAGAAAAAAGCACTGGACTGAGAAAAAAGCA
CTGGACTGA | | Citation | Peters MA, Cepko CL (2002). The dorsal-ventral axis of the neural retina is divided into multiple domains of restricted gene expression which exhibit features of lineage compartments. Dev Biol. 2002 Nov 1;251(1):59-73. | | Copyright | "Reprinted from Developmental Biology, 251(1), Peters MA, Cepko CL, The dorsal-ventral axis of the neural retina is divided into multiple domains of restricted gene expression which exhibit features of lineage compartments, 59-73, Copyright (2002), with permission from Elsevier". Copyright © ( 2002) Elsevier B.V. All rights reserved. |
| Stage | Image (click image to view full size) | Location (click to highlight) | Comments (click to highlight) | | 13-18 |  | | stage 17 |
 | | stage 18 |
 | | stage 18 |
 | | stage 18 |
| Retina
| | 19-24 |  | | stage 19 |
 | | stage 22 |
| Retina
| | 31-44 |  | | stage 44 |
 | | stage 44 |
| |
Entry 3| GEISHA Id | Vax.Zhang.2001 | Data Source | Publication | | Complete cDNA Template Probe | show GTTGTTGCTTTTTTTGTTTTCTTTTTATTGCACTACATGTTTGGGAAACAAGACAAAATGGACGTTAGATGCAGCACAG
AGACTGAAGCCAATCGGGTCTCGAAGAACGGACACAAGGAGGGCAAGGACAGCAAAGGGGCTGAAGGAAATATCTCTAC
TTCTTTTCTGAAGGAGCAACAAGGGACTTTTTCTGCCTCCGCAGCTACCGAAGACTGTAACAAAAGTAAATCTGGTTCG
GCGGACCCGGACTACTGCAGGAGGATCCTGGTCAGAGATGCCAAAGGTTCCATCCGAGAGATCATCCTGCCCAAAGGCC
TCGATTTGGACCGTCCCAAGCGGACCCGCACCTCCTTCACGGCCGAGCAGCTCTACCGCCTGGAGATGGAGTTCCAGCG
GTGCCAGTACGTGGTGGGGCGGGAGCGCACCGAGCTGGCGCGGCAGCTCAACCTCTCCGAGACTCAGGTAAAGGTGTGG
TTCCAGAACCGACGCACCAAGCAGAAAAAGGACCAGGGCAAAGACTCGGAGCTGCGTTCGGTGGTATCCGAGACCGCCG
CCACCTGCAGCGTCCTGCGGCTGCTGGAGCAGGGCCGCCTGCTCTCCCCGCCTGGGCTGCCCGGCCTCCTTGCCGCCCT
GTGCCAGCGGAACGCTGGGCTCGGCGCTGCGGGGCCCCGGCCTCTGGCTGCGGGCAGCGGCACGGCGGCGGCGGCGGCG
GCGGCGGCGGCTCCGGCCGGGGGATCCCCGCACCCCCCGAGCGCCGGCACCGCGGCGGGGCCGCCCCCTCCGGCAGCGC
TGCACGGAACGGCCGCCGCCGCCGCCGGGCACGGGCTCTTCGGGCTGCCGGTGCCCACGCTGCTGGGCTCGGTGGCGGG
GCGGCTCTCCTCCGCGCCGCTGGCCGTGGCGGGCTCGCTGGCGGGCAACTTGCAGGAACTGTCGGCCCGCTACCTGAGC
TCGTCCGCCTTCGAGCCCTACTCCCGGACCAACAATAAAGAAAGCGCTGAGAAAAAAGCACTGGACTGAGAAAAAAGCA
CTGGACTGA | | Citation | Zhang XM, Yang XJ (2001). Temporal and spatial effects of Sonic hedgehog signaling in chick eye morphogenesis. Dev Biol. 2001 May 15;233(2):271-90. | | Copyright | Copyright © 2001 Academic Press. All rights reserved. | | Comments | Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204799). |
| Stage | Image (click image to view full size) | Location (click to highlight) | Comments (click to highlight) | | 19-24 |  | | stage 22 |
 | | stage 22 |
 | | stage 24 |
 | | stage 24 |
| Eye
Retina
|
Entry 4| GEISHA Id | VAX.Halilagic.2007 | Data Source | Publication | | Complete cDNA Template Probe | show GTTGTTGCTTTTTTTGTTTTCTTTTTATTGCACTACATGTTTGGGAAACAAGACAAAATGGACGTTAGATGCAGCACAG
AGACTGAAGCCAATCGGGTCTCGAAGAACGGACACAAGGAGGGCAAGGACAGCAAAGGGGCTGAAGGAAATATCTCTAC
TTCTTTTCTGAAGGAGCAACAAGGGACTTTTTCTGCCTCCGCAGCTACCGAAGACTGTAACAAAAGTAAATCTGGTTCG
GCGGACCCGGACTACTGCAGGAGGATCCTGGTCAGAGATGCCAAAGGTTCCATCCGAGAGATCATCCTGCCCAAAGGCC
TCGATTTGGACCGTCCCAAGCGGACCCGCACCTCCTTCACGGCCGAGCAGCTCTACCGCCTGGAGATGGAGTTCCAGCG
GTGCCAGTACGTGGTGGGGCGGGAGCGCACCGAGCTGGCGCGGCAGCTCAACCTCTCCGAGACTCAGGTAAAGGTGTGG
TTCCAGAACCGACGCACCAAGCAGAAAAAGGACCAGGGCAAAGACTCGGAGCTGCGTTCGGTGGTATCCGAGACCGCCG
CCACCTGCAGCGTCCTGCGGCTGCTGGAGCAGGGCCGCCTGCTCTCCCCGCCTGGGCTGCCCGGCCTCCTTGCCGCCCT
GTGCCAGCGGAACGCTGGGCTCGGCGCTGCGGGGCCCCGGCCTCTGGCTGCGGGCAGCGGCACGGCGGCGGCGGCGGCG
GCGGCGGCGGCTCCGGCCGGGGGATCCCCGCACCCCCCGAGCGCCGGCACCGCGGCGGGGCCGCCCCCTCCGGCAGCGC
TGCACGGAACGGCCGCCGCCGCCGCCGGGCACGGGCTCTTCGGGCTGCCGGTGCCCACGCTGCTGGGCTCGGTGGCGGG
GCGGCTCTCCTCCGCGCCGCTGGCCGTGGCGGGCTCGCTGGCGGGCAACTTGCAGGAACTGTCGGCCCGCTACCTGAGC
TCGTCCGCCTTCGAGCCCTACTCCCGGACCAACAATAAAGAAAGCGCTGAGAAAAAAGCACTGGACTGAGAAAAAAGCA
CTGGACTGA | | Citation | Halilagic A, Ribes V, Ghyselinck NB, Zile MH, Dollé P, Studer M. Retinoids control anterior and dorsal properties in the developing forebrain. Dev Bio 2007 Mar 1;303(1):244-58 | | Copyright | Reprinted with permission from Elsevier.
Copyright © 2007 Elsevier B.V. All rights reserved. | | Comments | As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204799.1). |
| Stage | Image (click image to view full size) | Location (click to highlight) | Comments (click to highlight) | | 19 |  | | stage 19 |
 | | stage 19 |
| Eye
Head Mesenchyme
|
Entry 5| GEISHA Id | cVAX.Schulte.2005 | Data Source | Publication | | Complete cDNA Template Probe | show GTTGTTGCTTTTTTTGTTTTCTTTTTATTGCACTACATGTTTGGGAAACAAGACAAAATGGACGTTAGATGCAGCACAG
AGACTGAAGCCAATCGGGTCTCGAAGAACGGACACAAGGAGGGCAAGGACAGCAAAGGGGCTGAAGGAAATATCTCTAC
TTCTTTTCTGAAGGAGCAACAAGGGACTTTTTCTGCCTCCGCAGCTACCGAAGACTGTAACAAAAGTAAATCTGGTTCG
GCGGACCCGGACTACTGCAGGAGGATCCTGGTCAGAGATGCCAAAGGTTCCATCCGAGAGATCATCCTGCCCAAAGGCC
TCGATTTGGACCGTCCCAAGCGGACCCGCACCTCCTTCACGGCCGAGCAGCTCTACCGCCTGGAGATGGAGTTCCAGCG
GTGCCAGTACGTGGTGGGGCGGGAGCGCACCGAGCTGGCGCGGCAGCTCAACCTCTCCGAGACTCAGGTAAAGGTGTGG
TTCCAGAACCGACGCACCAAGCAGAAAAAGGACCAGGGCAAAGACTCGGAGCTGCGTTCGGTGGTATCCGAGACCGCCG
CCACCTGCAGCGTCCTGCGGCTGCTGGAGCAGGGCCGCCTGCTCTCCCCGCCTGGGCTGCCCGGCCTCCTTGCCGCCCT
GTGCCAGCGGAACGCTGGGCTCGGCGCTGCGGGGCCCCGGCCTCTGGCTGCGGGCAGCGGCACGGCGGCGGCGGCGGCG
GCGGCGGCGGCTCCGGCCGGGGGATCCCCGCACCCCCCGAGCGCCGGCACCGCGGCGGGGCCGCCCCCTCCGGCAGCGC
TGCACGGAACGGCCGCCGCCGCCGCCGGGCACGGGCTCTTCGGGCTGCCGGTGCCCACGCTGCTGGGCTCGGTGGCGGG
GCGGCTCTCCTCCGCGCCGCTGGCCGTGGCGGGCTCGCTGGCGGGCAACTTGCAGGAACTGTCGGCCCGCTACCTGAGC
TCGTCCGCCTTCGAGCCCTACTCCCGGACCAACAATAAAGAAAGCGCTGAGAAAAAAGCACTGGACTGAGAAAAAAGCA
CTGGACTGA | | Citation | Schulte D, Peters MA, Sen J, Cepko CL. The rod photoreceptor pattern is set at the optic vesicle stage and requires spatially restricted cVax expression. J Neurosci. 2005 Mar 16;25(11):2823-31. | | Copyright |
Copyright © 2012 by the Society for Neuroscience
| | Comments | As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_204799.1 |
| Stage | Image (click image to view full size) | Location (click to highlight) | Comments (click to highlight) | | 13-16 |  | | stage 16 |
 | | stage 16 |
 | | stage 16 |
| Eye
Face Mesenchyme
|
Entry 6| GEISHA Id | cVAX.Smith.2018 | Data Source | Publication | | Complete cDNA Template Probe | show ATGTTTGGGAAACAAGACAAAATGGACGTTAGATGCAGCACAGAGACTGAAGCCAATCGGGTCTCGAAGAACGGACACA
AGGAGGGCAAGGACAGCAAAGGGGCTGAAGGAAATATCTCTACTTCTTTTCTGAAGGAGCAACAAGGGACTTTTTCTGC
CTCCGCAGCTACCGAAGACTGTAACAAAAGTAAATCTGGTTCGGCGGACCCGGACTACTGCAGGAGGATCCTGGTCAGA
GATGCCAAAGGTTCCATCCGAGAGATCATCCTGCCCAAAGGCCTCGATTTGGACCGTCCCAAGCGGACCCGCACCTCCT
TCACGGCCGAGCAGCTCTACCGCCTGGAGATGGAGTTCCAGCGGTGCCAGTACGTGGTGGGGCGGGAGCGCACCGAGCT
GGCGCGGCAGCTCAACCTCTCCGAGACTCAGGTAAAGGTGTGGTTCCAGAACCGACGCACCAAGCAGAAAAAGGACCAG
GGCAAAGACTCGGAGCTGCGTTCGGTGGTATCCGAGACCGCCGCCACCTGCAGCGTCCTGCGGCTGCTGGAGCAGGGCC
GCCTGCTCTCCCCGCCTGGGCTGCCCGGCCTCCTGCCGCCCTGTGCCAGCGGAGCGCTGGGCTCGGCGCTGCGGGGCCC
CGGCCTGGCTGCGGGCAGCGGCACGGCGGCGGCGGCGGCGGCGGCGGCGGCTCCGGCCGGGGGATCCCCGCACCCCCCG
AGCGCCGGCACCGCGGCGGGGCCGCCCCCTCCGGCAGCGCTGCACGGAGCGGCCGCCGCCGCCGCCGGGCACGGGCTCT
TCGGGCTGCCGGTGCCCACGCTGCTGGGCTCGGTGGCGGGGCGGCTCTCCTCCGCGCCGCTGGCCGTGGCGGGCTCGCT
GGCGGGCAACTTGCAGGAACTGTCGGCCCGCTACCTGAGCTCGTCCGCCTTCGAGCCCTACTCCCGGACCAACAATAAA
GAAAGCGCTGAGAAAAAAGCACTGGACTGA | | Citation | Jonathan N Smith, Heather M Walker, Hannah Thompson, J Martin Collinson, Neil Vargesson, Lynda Erskine. Lens-regulated retinoic acid signalling controls expansion of the developing eye. Development. 2018 Oct 10;145(19):dev167171. DOI: 10.1242/dev.167171. | | Copyright | Copyright © 2018. Published by The Company of Biologists Ltd. | | Comments | Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204799.3). cVAX is Also known as VAX1. |
| Stage | Image (click image to view full size) | Location (click to highlight) | Comments (click to highlight) | | 19-23 |  | | stage 23 |
| Retina
| | all | | |
| | Data from NCBI Unigene EST Profile
Unigene ID: Gga.321 |
MouseFrogFruit FlyZebra FinchZebrafish |
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