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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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HOXA11
homeobox A11

The human orthologue of this gene is associated
with the following human disease:

Radioulnar synostosis with amegakaryocytic thrombocytopenia

Gene

Official Symbol	HOXA11
Official Full Name	homeobox A11
CGNC ID	49268
also known as	GHOX1I, chox-1.9, ghox-1I, homeobox protein Hox-A11\|Hox A11 variant 1\|Hox A11 variant 2\|homeo box A11\|homeobox protein Hox-1.9\|homeodomain-containing protein, Homeobox protein Hox-A11 , Ghox-1I, Chox-1.9
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_204619
Polypeptide	NP_989950
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.957

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	3207	ENSG00000005073	MIM:605432	MIM:142958
Mouse	15396	ENSMUSG00000038210	All phenotypic alleles (6):Targeted, knock-out(4) Targeted, other(2)	MGI:96172
Xenopus	100485262, 398250			483241
Zebrafish	30382, 58061	ENSDARG00000009045	ZDB-GENE-990415-4, ZDB-GENE-000823-8	ZFIN:ZDB-GENE-990415-4, ZFIN:ZDB-GENE-000823-8

Gene Ontology

Molecular Function	sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity
Biological Process	anterior/posterior pattern specification, branching involved in ureteric bud morphogenesis, more...
Cellular Component	cytoplasm, nucleolus, protein-DNA complex, transcription factor complex

Links to other databases

Entrez Gene	395327
Ensembl Gene	ENSGALG00000023130
KEGG	gga:395327

Entry 1

GEISHA Id	HOXA-11.Reid.2002	Data Source	Publication
Complete cDNA Template Probe	show CTTCTTCAGTGTCTACATAAACAAAGAGAAACGCCTCCAGCTCTCCCGAATGCTCAATCTGACCGACCGCCAAGTAAAA ATATGGTTTCAAAACAGAAGAATGAAAGAAAAAAAAATTAACAGGGACCGATTACAATATTACTCAGCTAATCCACTAC TTTAAAACTCGTAGCGTTTTTCAAGACGAGATTAAATTCAGATTTCGCCCTTGACAAGGTCAAGCCACGAGGTTACGTG GAGGAAGGAGGTGTGTATCTGACGGGACTCGAAGAACCCGAGGTTTTCCGTACATGTAAATCTGCTCTGGACCTTCCGT GACGGTTTATTGTTTTGTCTATATATTTACGTACCAACTGGAATCGGTTTGATTTTCGCACACGTGGCGTCCATCCATT TCCACCGCGCGCGTCACCTCCGAGCGCCCGGCCCAACGCCTCTCACCTTCCCGGGCACCGCGGCTCCGGGAGGGGACGG GGGTGTCCCCGTGTCCCGCTGCCCCC
Citation	Reid AI, Gaunt SJ. Colinearity and non-colinearity in the expression of Hox genes in developing chick skin. Int J Dev Biol. 2002 Mar
Copyright	Copyright © 2007 UBC Press
Comments	Hoxa-11, a ca. 500 base probe extending 3' of nucleotide 55 in the homeobox. This probe was estimated (nt 764-1264) from NM_204619 after mapping the homeobox to nt 709-924 of NM_204619.

Stage

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Location (click to highlight)

Comments (click to highlight)

25-30

stage 30

Dermis
Leg
Spinal Cord
Surface Ectoderm

31-44

stage 44

Entry 2

GEISHA Id	HOXA11.Mercader.2000	Data Source	Publication
Complete cDNA Template Probe	show GAGAGGCGGAGGCGGCCGGAGAGCGGCAGCAGCCCCGAGTCATCTTCCGGCAACAATGAGGAGAAATCCGGCAGCTCCA GTGGACAACGGACCCGTAAAAAGAGATGCCCCTACACCAAATATCAGATTAGAGAGCTAGAAAGGGAATTCTTCTTCAG TGTCTACATAAACAAAGAGAAACGCCTCCAGCTCTCCCGAATGCTCAATCTGACCGACCGCCAAGTAAAAATATGGTTT CAAAACAGAAGAATGAAAGAAAAAAAAATTAACAGGGACCGATTACAATATTACTCAGCTAATCCACTACTTTAAAACT CGTAGCGTTTTTCAAGACGAGATTAAATTCAGATTTCGCCCTTGACAAGGTCAAGCCACGAGGTTACGTGGAGGAAGGA GGTGTGTATCTGACGGGACTCGAAGAACCCGAGGTTTTCCGTACATGTAAATCTGCTCTGGACCTTCCGTGACGGTTTA TTGTTTTGTCTATATATTTACGTACCAACTGGAATCGGTTTGATTTTCGCACACGTGGCGTCCATCCATTT
Citation	Mercader N, Leonardo E, Piedra ME, Martínez-A C, Ros MA, Torres M. Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes. Development. 2000 Sep;127(18):3961-70.
Copyright	© The Company of Biologists Limited 2000
Comments	The sequence below was obtained from NCBI (acc #:NM_204619.1- Showing 545 bp region from base 616 to 1160) using the information provided in the publication.

Stage

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Location (click to highlight)

Comments (click to highlight)

19-23

stage 22

stage 23

Limb Buds

Stage 22 embryo + 18 hours
Stage 22 embryo + 5 hours
Stage 23 embryo + 24 hours
control embryo = left side

Entry 3

GEISHA Id	Hoxa-11.Nelson.1996	Data Source	Publication
Complete cDNA Template Probe	show CTCAGCTAATGCGGAGAAGCCGAGGTAGCCCTAATGATGGATTTTGATGAGCGTGTTCCTTGTTCCTCTAACATGTATT TGCCAAGTTGTACGTACTACGTCTCGGGTCCTGATTTCTCCAGCCTCCCTTCTTTTCTGCCCCAGACCCCGTCTTCTCG CCCTATGACATACTCCTACTCCTCCAACCTGCCCCAGGTCCAACCCGTGAGAGAAGTGACCTTCAGGGAATATGCCATT GATCCCTCCAGTAAATGGCACCCCCGGAACAACCTGCCCCACTGCTACTCCGCAGAGGAGATCATGCACAGAGACTGCT TGCCTTCCACCACCACCGCCAGCATGGGCGAGGTGTTCGGCAAAAGCACCGCGAACGTCTACCACCACCCCAGCGCCAA CGTCTCCTCCAATTTCTATAGCACGGTGGGCAGGAACGGGGTCCTGCCGCAGGCTTTCGACCAGTTTTTCGAGACGGCG TACGGCACGGCGGAGAACCCGTCCTCCGCGGACTATCCGCCGGACAAGAGCGGCGAGAAGGCGCCCGCGGCCGCCGGGG CGACGGCGGCAACTTCAAGTTCGGAGGGCGGCTGCGGCGGGGCGGCGGCGGCGGCGGGGAAGGAGAGGCGGAGGCGGCC GGAGAGCGGCAGCAGCCCCGAGTCATCTTCCGGCAACAATGAGGAGAAATCCGGCAGCTCCAGTGGACAACGGACCCGT AAAAAGAGATGCCCCTACACCAAATATCAGATTAGAGAGCTAGAAAGGGAATTCTTCTTCAGTGTCTACATAAACAAAG AGAAACGCCTCCAGCTCTCCCGAATGCTCAATCTGACCGACCGCCAAGTAAAAATATGGTTTCAAAACAGAAGAATGAA AGAAAAAAAAATTAACAGGGACCGATTACAATATTACTCAGCTAATCCACTACTTTAAAACTCGTAGCGTTTTTCAAGA CGAGATTAAATTCAGATTTCGCCCTTGACAAGGTCAAGCCACGAGGTTACGTGGAGGAAGGAGGTGTGTATCTGACGGG ACTCGAAGAACCCGAGGTTTTCCGTACATGTAAATCTGCTCTGGACCTTCCGTGACGGTTTATTGTTTTGTCTATATAT TTACGTACCAACTGGAATCGGTTTGATTTTCGCACACGTGGCGTCCATCCATTTCCACCGCGCGCGTCACCTCCGAGCG CCCGGCCCAACGCCTCTCACCTTCCCGGGCACCGCGGCTCCGGGAGGGGACGGGGGTGTCCCCGTGTCCCGCTGCCCCC TCGGAGCGTGGCGTGGGCACCGGCACCGCGAGCGGCCGCAGCCGGGACGCAAACTTTGGGAAACGATCTCTCTTCCTTC CCGGAGGAAAAACGTCTGTGGTTGAGGCAGTGCGCCATTGCCCATGGGTTTGAAAGGGGAATTAAGGGAGGGGGGAGAG AAGTAAAGGGGAGGGGGGGGGGGGGCGACGTGCCTACACCTTCACGAGGCCGACCACGAGCAGTTGTAACGTGGATGTA GCGATGGGTACGATAGTGTTTCCTTTGGGGTGGGAGGAAGCGGGGAAGGGGGTGGGAAGAGAAAGAACCGAAAGACTGA AATATTTACTTTAAAAAGAAAAAAAAATCAGGTATAAATTTTGCCATACATCGCAAGGAAACAATCACTGAAAAGGCAA AGAAAAGAAAAACAAAGCGAAGATTTCTCCAGTTGTAACTAGCTCTCGTTTTATTTATGACAACGGCCTGCGCGTTGCC ATCTTTTCGGAGACAAATCATATTTAAATGCTAAAAATAAAGCGTCAAAGGGGGGGAAAAAAAAGAAGTGTGAATTTCA GCGTTTTTAAAGAAAAAAAAATAAGGAGAGGAAACGAACCTCCCGGCTTCTGGCTCGCAAACTTTCTTCAGGAAATACC TGTGGAGAACGACAGTTTAGCAAATACCACACAACACTTAATTGAAACTTGGAGTTGTGCAATGCGCTAACGTTGGGTC ATTAAAATAACTCAATCGCATGCTCTTGTAAAGGTGACCAGTGAGGAGTCGAATCAGAAGCCAAACAGTGTAAATACGG TCGTTTTGTTGTCGTCTACTTTAAATGTCACGAGCTCTACTTTGTCGCCCAGCCGACGTATGCAAAGAACGGAGAGTTG TTCGGAGTTATTTTAAGTATCTATAAATATATATATTTCCCTGCAGGAACCAAAGCGTGAAAAAATAAAAAAAAAAAAA
Citation	Nelson CE, Morgan BA, Burke AC, Laufer E, DiMambro E, Murtaugh LC, Gonzales E, Tessarollo L, Parada LF, Tabin C. Analysis of Hox gene expression in the chick limb bud. Development. 1996 May;122(5):1449-66.
Copyright	Copyright © 1996 by Company of Biologists
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204619 ).