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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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PDGFC
platelet derived growth factor C

Gene

Official Symbol	PDGFC
Official Full Name	platelet derived growth factor C
CGNC ID	7129
also known as	SCDGF, platelet-derived growth factor C\|PDGF-C\|spinal cord-derived growth factor
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_204721
Polypeptide	NP_990052
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.1907

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	56034			MIM:608452
Mouse	54635	ENSMUSG00000028019	All phenotypic alleles (8):Targeted, knock-out(3) Targeted, other(4) Gene trapped(1)	MGI:1859631
Xenopus	100494492			985687
Zebrafish	560564	ENSDARG00000077588	ZDB-GENE-071217-2	ZFIN:ZDB-GENE-071217-2

Gene Ontology

Molecular Function	growth factor activity, platelet-derived growth factor receptor binding, more...protein homodimerization activity
Biological Process	activation of transmembrane receptor protein tyrosine kinase activity, more...
Cellular Component	cell surface, extracellular space, membrane

Links to other databases

Entrez Gene	395469
Ensembl Gene	ENSGALG00000009378
KEGG	gga:395469

Entry 1

GEISHA Id	PDGFC.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	TTATAAAAGCTTGCGGCCGCAGAATATGGTTCCAGTAGTGTGCCAAGTAGAC
Reverse cDNA Template Primer	GCTCTAGAAATTAACCCTCACTAAAGGCTCATTGATGCCTTTCTCCCG	cDNA Template Length	893
Forward cDNA Template Probe	show NNTTTAAGNNTTGTTTTCNNNNNTTTCCAAATCTGCAAGGACACCAGATCAGAATAAGATTTGTGTCTGATGAATATTT TCCTTCTTAACCGGGCATTCTGCATCCATTATACAACTTCTTGTGCCACACCACACAGAAGCACCATAGCCCATCGTCG CTACCCCCATCAGCTTTGCCACTAGATGTATTGAACGATGCTGTTGCTGGATTTAGTACTGTGGAAGAACTTATCCGGT ACCTTGAACCACATCGGTGGCAGCTGGATTTGGAAGACTTGGACAGGCCGAACGTGGCAACTTCTTGGAAAGGCATATA TTCATGGGAGAAAATCGAGAGTGGTTGATCTCAACTTGGTAAAGGAGGAAGTGCGGCTGTATAGTTGTACTCCTCGCAA CTTCTCATTGTCACTGAGAGAGGAGCTGAAGCGAACTGACACCATTTTCTGGCCACTGTGTCTTCTGGTTAAGCGTTGT GGTGGAAACTGTGCCTGTTGTCATCAGAACTGCAATGAGTGCCAATGTATACCAACAAAAGTCACCAAAAAGTACCACG AGGTTCTTCAGCTGATGCCAAGGAGTGGTGTCCGAGGACTGCATATATCACTGACTGATGTACTCTTGGAACACCACCA TGAGTGTGACTGTGTATGCAAAGGGAATAGTGAAGGATAAACATGATTTACTTGTGCTGTTTTCTTTGAAGCACGTTCA ATCCTTGCTGATTCTATTATGGGGCTTGTGCATTATCTCCTTCTGTAATCTCAGTTGTTTGCTTTGGGGAACTTCCGTC TTCAAGATTTACAGTGAGCTCTAAAAAGAGAAACAAAACTGGGAATATGTGATGTATGACGACTCTGTTTGGATGCCCA ATTAACGACTGGAGAAAGCATCAATGATCCTTTAGTGGGGGTTATTTTTTAAAAACAAA
Comments	No specific expression detected at or below stage 12.

Stage

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Location (click to highlight)

Comments (click to highlight)

13-18

stage 18

Lung

19-24

stage 21

Leg Mesenchyme
Lung
Retina
Spinal Ganglia and Nerves
Wing Mesenchyme

stage 25

Head Mesenchyme
Leg Mesenchyme
Retina
Somatic Mesoderm
Spinal Ganglia and Nerves
Wing Mesenchyme

Entry 2

GEISHA Id	PDGFC.McCabe.2008	Data Source	Publication
Complete cDNA Template Probe	show ANTCAGNGCTGCCTACTCCCCTGGCGGCGCTGAGAGACGCCCGGGCCTCGGTGCCGCTCCGCCAGCGCCTGCTCCGCCG CAGCCCCTCGCCCCGCCGGCCCAATGCTCCTCCTCGGGCTGCTCCTGCTGACATCCGCCCTGGCCGGCCGGAGGCATGG GGCCGCCGCGGAGTCCGACCTCAGCAGCAAGTTCTCCTTCCCCGGCGCTAAGGAGCAGAACGGTGTGCAGGATCCTCAG CATGAGAAAATAATAACTGTGACTTCTAATGGAAGTATTCACAGCCCCAAGTTTCCACACACATACCCACGCAATACTG TACTGGTGTGGAGATTAGTAGCAGTAGATGAAAATGTATGGATACAACTTACTTTTGATGAAAGATTTGGGCTTGAGGA CCCAGAAGATGATATTTGCAAGTATGACTTTGTAGAAGTTGAAGAACCTAGTGATGGCACTGTTTTAGGGCGCTGGTGT GGTTCCAGTAGTGTGCCAAGTAGACAAATCTCCAAAGGAAACCAGATCAGAATAAGATTTGTGTCTGATGAATATTTTC CTTCTCAACCTGGATTCTGCATCCATTATACACTTCTTGTGCCACACCACACAGAAGCACCTAGCCCATCATCGCTACC CCCATCAGCTTTGCCACTAGATGTATTAAACAATGCTGTTGCTGGATTTAGTACTGTGGAAGAACTTATCCGGTACCTT GAACCAGATCGGTGGCAGCTGGATTTGGAAGACTTGTACAGGCCAACGTGGCAACTTCTTGGAAAGGCATATATTCATG GGAGAAAATCAAGAGTGGTTGATCTCAACTTGCTAAAGGAGGAAGTGCGGCTGTATAGTTGTACTCCTCGCAACTTCTC AGTGTCACTGAGAGAGGAGCTGAAGCGAACTGACACCATTTTCTGGCCACTGTGTCTTCTGGTTAAGCGTTGTGGTGGA AACTGTGCCTGTTGTCATCAGAACTGCAATGAGTGCCAATGTATACCAACAAAAGTCACCAAAAAGTACCACGAGGTTC TTCAGCTGAAGCCAAGGAGTGGTGTCCGAGGACTGCATAAATCACTGACAGATGTACCCTTGGAACACCACGAGGAGTG TGACTGTGTATGCAAAGGGAATAGTGAAGGATAAACATGATTTAATTGTGCTGTTTTCTTTGAAGCACGTTCAATCCTT GCTGATTCTATTATGGGGCTTGTGCATTATCTCCTTCTGTAATCTCAGTTGTTTGCTTTGGGGAACTTCCATCTTCAAG ATTTACAGTGAGCTCTAAAAAGAGAACCAAAACTGGGATTATGTGATGTATGACAGCTCTGTTTGGAGGCCCAGTTAAA GGACGGGAGAAAGGCATCAATGAGGGATTTAAAATACATGTTGTTGTTGGTTTTGTTTTTTTTTTCTTTTTGTCCCCTC CAGTTTTCTTGACAATACATGGATTTATAATTTAGGAGTAAAAATAAAGTTAGGAGGCTTGCATCATGGAGACTTGATC CTGCTGGCTGTTTCATTTCTACACCTCCAGAACATCTGGCCCCTAGCTGAAAACATCTGAAATCTTTCTGTGTTCAACT ACTCCTATGTACTCNAAACATTCTCTGCTTTATAATTTGGTTTATAACANACTGTCTTGTTCTGAATTAAACTTAATTT GTCTAAAAAAAAAAAA
Citation	McCabe KL, Bronner-Fraser M. Essential role for PDGF signaling in ophthalmic trigeminal placode induction. Development. 2008 May;135(10):1863-74. Epub 2008 Apr 16.
Copyright	Published by The Company of Biologists 2007. This material is protected by a copyright retained by the authors. Permission granted by Dr. Bronner-Fraser.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204721).

Stage

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Location (click to highlight)

Comments (click to highlight)

7-10

stage 8

stage 10

Ectoderm
Intermediate Mesoderm
Lateral Plate Mesoderm
Midbrain
Primitive Streak
Somites
Surface Ectoderm

Entry 3

GEISHA Id	PDGFC.Yang.2008	Data Source	Publication
Complete cDNA Template Probe	show TACGCGGGCTAGCACAGATTTGGGCTTGAGGACCCAGAAGATGACATTTGCAAGTATGACTTTGTAGAAGTTGAAGAAC CTAGTGATGGCACTGTTTTAGGGCGCTGGTGTGGTTCCAGTAGTGTGCCAAGTAGACAAATCTCCAAAGGAAACCAGAT CAGAATAAGATTGTGTCTGATGAATATTTTCCTTCTCAACCTGGATTCTGCATCCATTATACACTTCTTGTGCCACACC ACACAGAAGCACCTAGCCCATCATCGCTACCCCCATCAGCTTTGCCACTAGATGTATTAAACAATGCTGTTGCTGGATT TAGTACTGTGGAAGAACTTATCCGGTACCTTGAACCAGATCGGTGGCAGCTGGATTTGGAAGACTTGTACAGGCCAACG TGGCAACTTCTTGGAAAGGCATATATTCATGGGAGAAAATCAAGAGTGGTTGATCTCAACTTGCTAAAGGAGGAAGTGC GGCTGTATAGTTGTACTCCTCGCAACTTCTCAGTGTCACTGAGAGAGGAGCTGAAGCGAACTGACACCATTTTCTGGCC ACTGTGTCTTCTGGTTAAGCGTTGTGGTGGAAACTGTGCCTGTTGTCATCAGAACTGCAATGAGTGCCAATGTATACCA ACAAAAGTCACCAAAAAGTACCACGAGGTTCTTCAGCTGAAGCCAAGGAGTGGTGTCCGAGGACTTGCATAAATCACTG ACAGATGTACCCTTGGAACACCACGAGGAGTGTGACTGTGTATGCCAAAGGGAAATAGTGAAAGGATTACACCATGATT TTAAATTGTGCTGGTTTTTCTTTGAAAGACACGTTCAATCCCTTGCCTGATTTCTAATTATGGGGGCTTGTGCATTTAT CTCCTTCTGGTCAATCTCAAGTTGTTGGCTTTGGGGGAACTTCCCTTCTTCAAGAATTTACCCGTGAGCCTTAAAAAGA GAAAGCAAAACTGGGGATTCTGCTGAGGTTTGAC
Citation	Yang X, Chrisman H, Weijer CJ. PDGF signalling controls the migration of mesoderm cells during chick gastrulation by regulating N-cadherin expression. Development. 2008 Nov;135(21):3521-30. Epub 2008 Oct 2.
Copyright	© 2008
Comments	The cDNA template used to generate the probe was obtained from EST - ChEST270m4 as described in Yang et al.