Geisha

home

|

contact

A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

Quick Search

Data Class

Enter Text:

Gene Family QuickSearch

	Transcription Factors
	Growth Factors
	Receptors
	MicroRNAs

Human Disease Gene Search

	Downloads
	Protocols
	About GEISHA
	Contact Us

	Transgenic Birds
	Model Organism Databases
	Gene Expression Databases
	Genomic Resources
	Anatomical Atlases
	Chicken Stage Series

LEFTY2
left-right determination factor 2

Gene

Official Symbol	LEFTY2
Official Full Name	left-right determination factor 2
CGNC ID	49363
also known as	LEFTY1, left-right determination factor 1\|lefty
gene type	protein-coding

Genomic Map

	Ensembl ID not known
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_204764
Polypeptide	NP_990095
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.4956

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human
Mouse
Xenopus
Zebrafish	30146, 30145	ENSDARG00000044059, ENSDARG00000019920	ZDB-GENE-990630-11, ZDB-GENE-990630-10	ZFIN:ZDB-GENE-990630-11, ZFIN:ZDB-GENE-990630-10

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Links to other databases

Entrez Gene	395529
Ensembl Gene
KEGG	gga:395529

Entry 1

GEISHA Id	LEFTY2.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	TGGAGGGGAGGATACCAAAAAAC
Reverse cDNA Template Primer	ATTAACCCTCACTAAAGGTGGGGTGGGGACTGAAATAACC	cDNA Template Length	866
Forward cDNA Template Probe	show TAATACTCATGGACCCCTCAAATGCAGGAGGTGCACCTCCTCTGCGACCAGCAGCACCGGTTACTCCCCTAACTCAGTC CCTTTAAAAAGTGCTGCGCCATCTGCCATGCAGCTGCACTTCTCAATGATCATGTTGGGAAACTCAGTTGCTTCGGTCT CAATGTGGTTGCCCCTCCGGACCAAGTACGTGATGGGGAGTGGGGAGCTCTCGGCCACAGCGCACGCACGCTCCCTGCC CCCGCACATCTGTATTGGGCCAGGAAGCTGCAGGCCGGCCCCCCGTGATCTGTAAGTTGGGTATGCTGCCCGCTTCATC ACCCAGTACTGTGTACACGAAACCTCAGGGAAGTTGAAGTAGTGGCTCTGCCGGCATGACGTGGACTTCCCTGGCTGCC CTGCATCCTTGCAGGCCCCAGGGCCCCCATAGTCCTCCAACTGCAGGGTGTATAACACCAACTTGAGTCTTCCTAAGGC TCTGTCTACACCATACTGGGACGTGAAGCCCACCGGCTTGGCAACCCTAACTTGCCAGGGGCGCTGCCTTTCCCCTTCT ATCCACAATATACTGACCATTGGCAACGGACTTGTCTTTCCCATCATTAATAGCCACCCCTTTCTCACCTTATAATTGG TCCAGGACGGACTATCATATGGGAAACCTACCGCGAATTGAGTTTCCCCAAGGTCCTGTTTGTTACGTGCCAGCTGGAC TATTAACCCACGTCAAAACTTTATCTTAGGGAATTGGAATATAAGGGCAAATTCGGGTACCACTGGAGACCAGGAAACA CCTCCAAACTACCGTGCTTTTTGGAGAAACCTTTCCTTCTGGCTCATTTACCACTCCCCCGGCATATTAATTAATAGAC GCGCTTTAAAAAAAAATACCTTATGTTCCCACCCCAACGATCGACGCCCTGCTCGATGCAGTATCTGATTACATAAACA CTAAAAGATCACCCTTACTCTTAAGATCCTACTAATTCTGCCCCCAACACCATCACCATCATTACCCCAAAGCCTATCT CCTCCTCGAATTACAATCCTAAATAATATAAAACACTCATTTATCTCCACTCTTTCACACAACCTTCCTCTGTTTACTG CTATAACTCTATCCATATATCTTACAAATCCTAACATCATGACTTGTATATTACATATAATAGCATACTTTTTACATAA TAGATTTATACACACCTCATCATTAATCTATTTTTATATTAAGGTGTACTCTATACATGCAATTTGCATTACCTACACA CTCACTACTTCTCTATAGTCGAGTCTATAAGCATCCTTTATTCCAACAACTTCAATTACTCTACGCAGATGCCTCAGCG TTTATATATGCATTTTACACACAGCCTCGTACTCCTGTCGCAGTACTAAATAGACACCTATTACACACTTATAGTACCA CCAACATGCAATAGTCACTCATCTTGCCTAGATCAGACACAGCTTAGTACTTGCTATGCCTCGTCTCCTCTCACCAATC TGATATTACTATACCCATCCATACATCCCACTCTTGTCTGTATACGTAACTTTTATAATGATCTACGGCATACTCTCTT ACGCTGACGCTACTGCATTCTCATACGAATGACCATCCTACAGCACTAACCCTCCTACCATGCTCAA

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

19-24

stage 20

stage 23

25-26

stage 26

Entry 2

GEISHA Id	LEFTY2.Hardy.2011	Data Source	GEISHA ISH Analysis
Complete cDNA Template Probe	show CACCACAGCCCTGCTGACATCCCTGTTCCTCCCTGCGAGCCACCAACAGGCAGGATGGAGGTGAGCTTCACCCGGATGC TCTACGTGCTCTGTCTGGTTGCCATGGCCTGTGCGTTCACCCAGGAAGGGTTCAAAGAAGTGATGCTGAAGCAGCTGGG GCTCTCTGAAGTCCCTAAGCTTCATAAGAGAGATCTGGTGGACCTGGTCATCCCCGAGCATGTGAAGAACAAGTACATC TCCATGCTGAAGCGGCACAGGGGGAAGCGTCGTGCCTCTCCCAGCTTGGCCAGCATCCTGCAGGGGATCCCCGGCAATG CAGAAGTCTTCTACTCTGACCCCATGCGCCAGAACTTCATCTTTGACATGGAGGGGAGGATACCAAAAAACAGTGAAGT GACAATGGCTGAACTGAAGCTTTTCAAGAAGCCCCTGGACAGGGTGAACCTGCCAGCCAGGCAGCCCCATCGGCCCGTC TCCAATGCCAGGGTCAGCATCTACTGGGTGCAGAGACAGCACGACGGCACAAACAGGACCTCGCTGATCGACTCCCGGC TGGTTCCCATAAGAGAGTCAGGCTGGAAGAACTTTGACGTGACACAGGCTGTGCACTACTGGCTGCGGAACAAGAGGCA GGAGCCAATGGTCCTGCAGGTCTGGATCGAAGGGGAAAGGGTGGCGAGCTATGCTGCAGAGGTTGCCAAGTCCGTGCGC TTCACCTCACAGGATGCTGGAGACAGAGCCGTGGGAAGACCCGAGCTGGTGCTCTACACCCTTGACTTGGAGGACTACG GGGGCCCTGGGGACTGCAAGGATGGAGTGCAGGCAGGGAAGTCCACCTGCTGCCGGCAGAAGCACTACATCAACTTCCG TGAGCTCTCCTGGACACAGTACTGGGTCATCGAGCCGGCAGGATACCAGGCTTACAGCTGCCGGGGGGGCTGCCTGCAG CTTCCTGGCCCACTACAGCTCTGGGGGGGCAGGGAGCGTGCCTGTGCTGTGGCCGAGAGCTCCCCGCTCCCCATCATGT ACCTGGTCCGGAGGGGCAACCACACTGAGATTGAAGCAACTGAGTTTCCCAACATGATCATTGAGAAGTGCAGCTGCAT GGCAGATGGCGCAGACTTCTGTGAGGGGCTGACTTAGGGGAGTAACGGTGCTGCTGGGCCTGGAGGAGGTGCACCTCCC TGCATTTGGTGTGGCTGCCTCTGGGTTATTTCAGTCCCCACCCCAGGGCACTGCAAGCAGCTGCAGGTGAAAGGCAAGG ACAGTGATTACGGCCAGGTGCAAAAGTCGAGCTTGGGTTTGGATTTTAGTTCCTTGGTTCCCTGTGCTTTGTACGTTTT GGTCCTTGGCCCCAAGCTGTGTTTGCTGTGGACAGCAGAGCAAAAGCACTTACATGTATATGTTGTACATGCACACATA TGCACATGTATCACAAATGCATGTACATATATATGTATTGTATACGTGCATATTGTATATATACGCATTTTCTACATAC ATACATATATGTACATAGAATATTGCCTAGAGCTTAAATGAATGTATATATGTAAGTATGCATTGTATGCATATATCTG TAGATATACATGTACATACAACATTGTCCAGAACTCAAAGGACAGTATTGTTGACCCCTGCACCAAGAATTTGGCACAG TTTTAAGCAGAATTTGGAGTCCTGAAGCCAGTGGACATATTGGGATTTTGGTTTGCTTGCACAAATGATTGTTTATAGA ATCAGGTCCTCATTTTTCTGATTGCATATTACAGTTTTTTCAGTTAGAGCTATTTTTTGTAGTCTTAATAGCTTTCAAA ATTAAGTAGCATAAATATGATTATTAAAATAGCCAAAGAAAAAGAAAAAAAAAAAAAAAAANGTACTAGTCGAACGGGT GGNCAAGCG
Comments	Images provided by Katharine M. Hardy and Mary J.C. Hendrix, and funded by NIH award R01CA121205. Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc # NM_204764.1)

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

4-6

stage 5

stage 6

7-12

stage 7

stage 8

stage 9

stage 10

stage 11

stage 12

Lateral Plate Mesoderm
Notochord

13-18

stage 18

19

stage 19

Entry 3

GEISHA Id	LEFTY1.WangS.2004	Data Source	Publication
Complete cDNA Template Probe	show CACCACAGCCCTGCTGACATCCCTGTTCCTCCCTGCGAGCCACCAACAGGCAGGATGGAGGTGAGCTTCACCCGGATGC TCTACGTGCTCTGTCTGGTTGCCATGGCCTGTGCGTTCACCCAGGAAGGGTTCAAAGAAGTGATGCTGAAGCAGCTGGG GCTCTCTGAAGTCCCTAAGCTTCATAAGAGAGATCTGGTGGACCTGGTCATCCCCGAGCATGTGAAGAACAAGTACATC TCCATGCTGAAGCGGCACAGGGGGAAGCGTCGTGCCTCTCCCAGCTTGGCCAGCATCCTGCAGGGGATCCCCGGCAATG CAGAAGTCTTCTACTCTGACCCCATGCGCCAGAACTTCATCTTTGACATGGAGGGGAGGATACCAAAAAACAGTGAAGT GACAATGGCTGAACTGAAGCTTTTCAAGAAGCCCCTGGACAGGGTGAACCTGCCAGCCAGGCAGCCCCATCGGCCCGTC TCCAATGCCAGGGTCAGCATCTACTGGGTGCAGAGACAGCACGACGGCACAAACAGGACCTCGCTGATCGACTCCCGGC TGGTTCCCATAAGAGAGTCAGGCTGGAAGAACTTTGACGTGACACAGGCTGTGCACTACTGGCTGCGGAACAAGAGGCA GGAGCCAATGGTCCTGCAGGTCTGGATCGAAGGGGAAAGGGTGGCGAGCTATGCTGCAGAGGTTGCCAAGTCCGTGCGC TTCACCTCACAGGATGCTGGAGACAGAGCCGTGGGAAGACCCGAGCTGGTGCTCTACACCCTTGACTTGGAGGACTACG GGGGCCCTGGGGACTGCAAGGATGGAGTGCAGGCAGGGAAGTCCACCTGCTGCCGGCAGAAGCACTACATCAACTTCCG TGAGCTCTCCTGGACACAGTACTGGGTCATCGAGCCGGCAGGATACCAGGCTTACAGCTGCCGGGGGGGCTGCCTGCAG CTTCCTGGCCCACTACAGCTCTGGGGGGGCAGGGAGCGTGCCTGTGCTGTGGCCGAGAGCTCCCCGCTCCCCATCATGT ACCTGGTCCGGAGGGGCAACCACACTGAGATTGAAGCAACTGAGTTTCCCAACATGATCATTGAGAAGTGCAGCTGCAT GGCAGATGGCGCAGACTTCTGTGAGGGGCTGACTTAGGGGAGTAACGGTGCTGCTGGGCCTGGAGGAGGTGCACCTCCC TGCATTTGGTGTGGCTGCCTCTGGGTTATTTCAGTCCCCACCCCAGGGCACTGCAAGCAGCTGCAGGTGAAAGGCAAGG ACAGTGATTACGGCCAGGTGCAAAAGTCGAGCTTGGGTTTGGATTTTAGTTCCTTGGTTCCCTGTGCTTTGTACGTTTT GGTCCTTGGCCCCAAGCTGTGTTTGCTGTGGACAGCAGAGCAAAAGCACTTACATGTATATGTTGTACATGCACACATA TGCACATGTATCACAAATGCATGTACATATATATGTATTGTATACGTGCATATTGTATATATACGCATTTTCTACATAC ATACATATATGTACATAGAATATTGCCTAGAGCTTAAATGAATGTATATATGTAAGTATGCATTGTATGCATATATCTG TAGATATACATGTACATACAACATTGTCCAGAACTCAAAGGACAGTATTGTTGACCCCTGCACCAAGAATTTGGCACAG TTTTAAGCAGAATTTGGAGTCCTGAAGCCAGTGGACATATTGGGATTTTGGTTTGCTTGCACAAATGATTGTTTATAGA ATCAGGTCCTCATTTTTCTGATTGCATATTACAGTTTTTTCAGTTAGAGCTATTTTTTGTAGTCTTAATAGCTTTCAAA ATTAAGTAGCATAAATATGATTATTAAAATAGCCAAAGAAAAAGAAAAAAAAAAAAAAAAANGTACTAGTCGAACGGGT GGNCAAGCG
Citation	Wang S, Yu X, Zhang T, Zhang X, Zhang Z, Chen Y. Chick Pcl2 regulates the left-right asymmetry by repressing Shh expression in Hensen's node. Development. 2004 Sep;131(17):4381-91. Epub 2004 Aug 4.
Copyright	copyright 2004 to the authors. Published by the Company of Biologists Ltd.

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

4

stage 4

stage 4

Neural Plate/Tube

Entry 4

GEISHA Id	LEFTY1.Katsu.2012	Data Source	Publication
Complete cDNA Template Probe	show CATAAGAGAGATCTGGTGGACCTGGTCATCCCCGAGCATGTGAAGAACAAGTACATCTCCATGCTGAAGCGGCACAGGG GGAAGCGTCGTGCCTCTCCCAGCTTGGCCAGCATCCTGCAGGGGATCCCCGGCAATGCAGAAGTCTTCTACTCTGACCC CATGCGCCAGAACTTCATCTTTGACATGGAGGGGAGGATACCAAAAAACAGTGAAGTGACAATGGCTGAACTGAAGCTT TTCAAGAAGCCCCTGGACAGGGTGAACCTGCCAGCCAGGCAGCCCCATCGGCCCGTCTCCAATGCCAGGGTCAGCATCT ACTGGGTGCAGAGACAGCACGACGGCACAAACAGGACCTCGCTGATCGACTCCCGGCTGGTTCCCATAAGAGAGTCAGG CTGGAAGAACTTTGACGTGACACAGGCTGTGCACTACTGGCTGCGGAACAAGAGGCAGGAGCCAATGGTCCTGCAGGTC TGGATCGAAGGGGAAAGGGTGGCGAGCTATGCTGCAGAGGTTGCCAAGTCCGTGCGCTTCACCTCACAGGATGCTGGAG ACAGAGCCGTGGGAAGACCCGAGCTGGTGCTCTACACCCTTGACTTGGAGGACTACGGGGGCCCTGGGGACTGCAAGGA TGGAGTGCAGGCAGGGAAGTCCACCTGCTGCCGGCAGAAGCACTACATCAACTTCCGTGAGCTCTCCTGGACACAGTAC TGGGTCATCGAGCCGGCAGGATACCAGGCTTACAGCTGCCGGGGGGGCTGCCTGCAGCTTCCTGGCCCACTACAGCTCT GGGGGGGCAGGGAGCGTGCCTGTGCTGTGGCCGAGAGCTCCCCGCTCCCCATCATGTACCTGGTCCGGAGGGGCAACCA CACTGAGATTGAAGCAACTGAGTTTCCCAACATGATCATTGAGAAGTGCAGCTGCATGGCAGATGGCGCAGACTTCTGT GAGGGGCTGACTTAGGGGAGTAACGGTGCTGCTGGGCCTGGAGGAGGTGCACCTCCCTGCATTTGGTGTGGCTGCCTCT GGGTTATTTCAGTCCCCACCCCAGGGCACTGCAAGCAGCTGCAGGTGAAAGGCAAGGACAGTGATTACGGCCAGGTGCA AAAGTCGAGCTTGGGTTTGGATTTTAGTTCCTTGGTTCCCTGTGCTTTGTACGTTTTGGTCCTTGGCCCCAAGCTGTGT TTGCTGTGGACAGCAGAGCAAAAGCACTTACATGTATATGTTGTACATGCACACATATGCACATGTATCACAAATGCAT GTACATATATATGTATTGTATACGTGCATATTGTATATATACGCATTTTCTACATACATACATATATGTACATAGAATA TTGCCTAGAGCTTAAATGAATGTATATATGTAAGTATGCATTGTATGCATATATCTGTAGATATACATGTACATACAAC ATTGTCCAGAACTCAAAGGACAGTATTGTTGACCCCTGCACCAAGAATTTGGCACAGTTTTAAGCAG
Citation	Katsu K, Tokumori D, Tatsumi N, Suzuki A, Yokouchi Y. BMP inhibition by DAN in Hensen's node is a critical step for the establishment of left-right asymmetry in the chick embryo. Dev Biol. 2012 Mar 1;363(1):15-26.
Copyright	Copyright © 2012. Published by Elsevier Inc.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (Acc. # AF179483.1).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

7

stage 7

stage 7

Data from NCBI Unigene EST Profile
Unigene ID: Gga.4956

Mouse

Emage
Eurexpress
MGI GXD

Frog

Xenbase

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFIN	ZDB-GENE-990630-11, ZDB-GENE-990630-10

Home

|

Contact

University of Arizona

NICHD

National Institute of Health

Hy-Line

© 2008 Arizona Board of Regents
This website is hosted by the Biotechnology Computing Facility at the University of Arizona