GEISHA - A Chicken Embryo Gene Expression Database
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SOX14
SRY-box 14

Gene
Official SymbolSOX14
Official Full NameSRY-box 14
CGNC ID13049
also known asCH60, transcription factor SOX-14|HMG box transcription factor SOX14|SRY (sex determining region Y)-box 14|SRY-related protein CH60
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
UCSC
Sequence Information
Genomic
RNANM_204761
PolypeptideNP_990092
Gene Expression
In Situ HybridizationGEISHA
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human8403ENSG00000168875MIM:604747
Mouse20669ENSMUSG00000053747All phenotypic alleles (1):Targeted, other(1) MGI:98362
Xenopus100101715, 100337614485369
Zebrafish557661ENSDARG00000070929ZDB-GENE-051113-268ZFIN:ZDB-GENE-051113-268
Gene Ontology
Molecular Functionsequence-specific DNA binding
Biological Processnegative regulation of transcription from RNA polymerase II promoter, more...negative regulation of transcription, DNA-templated, transcription, DNA-templated
Cellular Componentnucleus
Links to other databases
Entrez Gene395526
Ensembl Gene
KEGGgga:395526
GEISHA IdSox14.Hargrave.2000Data SourcePublication
Complete cDNA Template Probeshow
CTCCTTACTTGACCCCAGCCAGTTCAGCTCCAGCGCCATTCAGAAGATGACCGAGGTTCCTCACACCTTGGCCACCGGC
ACCCTGCCCTACGCCTCCACCTTGGGATACCAGAACGGGGCGTTCGGCAGCCTGAGCTGCCCCAGCCAACACACCCACA
CCCACCCCTCGCCGACCAACCCGGGCTACGTGGTGCCGTGTAACTGTACCGCTTGGTCG
CitationHargrave M, Karunaratne A, Cox L, Wood S, Koopman P, Yamada T. The HMG box transcription factor gene Sox14 marks a novel subset of ventral interneurons and is regulated by sonic hedgehog. Dev Biol. 2000 Mar 1;219(1):142-53.
CopyrightReprinted with permission from Elsevier. Copyright © 2000 Elsevier B.V. All rights reserved.
CommentsAccording to the authors, "The primers used in this study were cSox14 (forward, TACTCCTTACTTGACCCAGCCAG; reverse, ACCAAGCGGTACAGTTACACGG; amplifying 217 nt at positions 511–727 nt)." The sequence below was obtained from NCBI (AF193760) using this information.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
13-18
stage 18
Spinal Cord
Lateral Intermediate Zone
19-24
stage 24
Spinal Cord
Lateral Intermediate Zone
25-28
stage 25
stage 25
stage 28
stage 28
Diencephalon
Hindbrain
Midbrain
Spinal Cord
Double labeled
Figure 3 compares the expression patterns of Sox14, Islet1 and Lim3 in a population of ventral interneurons in chick spinal cord at HH18, HH24 and HH28.
Lateral Intermediate Zone
Motor Neurons
Pretectum
Zona Limitans Intrathalamica

Mouse

EmageMGI:98362
MGI GXDMGI:98362

Frog

Xenbase485369

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-051113-268
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