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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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SMAD1
SMAD family member 1

Gene

Official Symbol	SMAD1
Official Full Name	SMAD family member 1
CGNC ID	7584
also known as	mothers against decapentaplegic homolog 1\|BMP pathway effector\|BMP signal transducer Smad1\|SMAD, mothers against DPP homolog 1, Smad1
gene type	protein-coding

Genomic Map

	Ensembl ID not known
	NCBI
	UCSC

Sequence Information

Genomic
RNA	NM_001201455
Polypeptide	NP_001188384

Gene Expression

In Situ Hybridization

GEISHA

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	33529			FBgn0011648
Human	4086			MIM:601595
Mouse	17125	ENSMUSG00000031681	All phenotypic alleles (11):Targeted, knock-out(5) Targeted, other(6)	MGI:109452
Xenopus	493211, 379664, 399457			1018192
Zebrafish	30628	ENSDARG00000027199	ZDB-GENE-991119-8	ZFIN:ZDB-GENE-991119-8

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Links to other databases

Entrez Gene	395680
Ensembl Gene
KEGG	gga:395680

Entry 1

GEISHA Id	Smad1.Zuzarte.2004	Data Source	Publication
Complete cDNA Template Probe	show GAAGAAGAAAAATGGGCAGAGAAGGCTGTTGATGCACTAGTGAAAAAACTAAAGAAGAAAAAAGGTGCTATGGAGGAGC TGGAGAAAGCGTTAAGCTGTCCTGGTCAGCCCAGCAACTGTGTCACAATTCCTCGGTCCTTGGATGGCCGGCTTCAGGT TTCACACCGGAAAGGGCTGCCGCATGTAATTTACTGCAGAGTGTGGCGCTGGCCAGACCTGCAAAGCCATCATGAACTG AAACCACTGGAATGCTGCGAGTTTCCTTTTGGTTCAAAACAGAAGGAGGTCTGCATCAATCCTTACCACTACAAGCGGG TAGAAAGTCCTGTTCTACCTCCGGTGCTGGTTCCAAGGCACAGCGAATACAACCCTCAGCACAGCCTCTTGGCTCAGTT CCGCAACTTGGGACAAAATGAGCCCCACATGCCACACAACGCTACTTTCCCGGACTCTTTTCAGCAACCCAACAGTCAC CCGTTCCCCCATTCGCCAAACAGCAGCTATCCAAACTCGCCTGGAAGCAGCAGTAGCACCTACCCACATTCTCCAGCCA GCTCAGACCCAGGAAGCCCTTTTCAGATGCCAGCTGATACTCCTCCTCCTGCTTACCTGCCTCCGGAAGATCAGATGAC ACACGATACCTCCCAGCCAATGGATACCAACATGATGGCACCCGGAATCCACCCTGACATACACAGAGGAGATGTTCAG GCTGTTGCTTATGAAGAGCCGAAGCATTGGTGC
Citation	Zuzarte-Luís V, Montero JA, Rodriguez-León J, Merino R, Rodríguez-Rey JC, Hurlé JM. A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways. Dev Biol. 2004 Aug 1;272(1):39-52.
Copyright	Reprinted from Developmental Biology, Volume 272, Issue 1, V Zuzarte-Luıs, J.A. Montero, J Rodriguez-León, R Merino, J.C Rodrıguez-Rey, and J.M Hurlé, A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways, Pages 39-52, Copyright 2004, with permission from Elsevier. Copyright © 2004 Elsevier B.V. All rights reserved.
Comments	Fragments of chicken Smad1 (744 bp)... ... genes were obtained by RT-PCR. cSmad1, 5′-GARGARGARAARTGGGC-3′ (sense) and 5′-RCACCARTGYTTNGGYTC-3′ (antisense).

Stage

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25-28

stage 28

Leg Mesenchyme
Wing Mesenchyme

Entry 2

GEISHA Id	SMAD1.LeDréau.2012	Data Source	Publication
Complete cDNA Template Probe	show ATGAACGTGACAAGTTTATTTTCCTTCACCAGCCCAGCAGTGAAGAGGCTGTTGGGGTGGAAGCAGGGAGATGAAGAAG AAAAATGGGCAGAGAAGGCTGTTGATGCACTAGTGAAAAAACTAAAGAAGAAAAAAGGTGCTATGGAGGAGCTGGAGAA AGCGTTAAGCTGTCCTGGTCAGCCCAGCAACTGTGTCACAATTCCTCGGTCCTTGGATGGCCGGCTTCAGGTTTCACAC CGGAAAGGGCTGCCGCATGTAATTTACTGCAGAGTGTGGCGCTGGCCAGACCTGCAAAGCCATCATGAACTGAAACCAC TGGAATGCTGCGAGTTTCCTTTTGGTTCAAAACAGAAGGAGGTCTGCATCAATCCTTACCACTACAAGCGGGTAGAAAG TCCTGTTCTACCTCCGGTGCTGGTTCCAAGGCACAGCGAATACAACCCTCAGCACAGCCTCTTGGCTCAGTTCCGCAAC TTGGGACAAAATGAGCCCCACATGCCACACAACGCTACTTTCCCGGACTCTTTTCAGCAACCCAACAGTCACCCGTTCC CCCATTCGCCAAACAGCAGCTATCCAAACTCGCCTGGAAGCAGCAGTAGCACCTACCCACATTCTCCAGCCAGCTCAGA CCCAGGAAGCCCTTTTCAGATGCCAGCTGATACTCCTCCTCCTGCTTACCTGCCTCCGGAAGATCAGATGACACACGAT ACCTCCCAGCCAATGGATACCAACATGATGGCACCCGGAATCCACCCTGACATACACAGAGGAGATGTTCAGGCTGTTG CTTATGAAGAGCCGAAGCATTGGTGCTCCATTGTTTATTACGAGCTGAATAATCGTGTTGGGGAGGCCTTCCATGCCTC TTCCACCAGCATCCTGGTGGATGGCTTCACTGATCCTTCAAACAACAAAAACAGATTTTGCCTGGGGCTGCTCTCCAAT GTTAACCGGAATTCCACCATTGAGAATACAAGGAGGCACATTGGAAAAGGTGTTCATCTCTATTATGTTGGTGGAGAAG TGTACGCTGAATGCCTCAGCGACAGCAGTATTTTTGTGCAAAGTCGAAACTGCAACTACCACCATGGTTTCCATCCAAC CACAGTGTGCAAAATTCCCAGTGGCTGCAGTTTGAAGATTTTCAATAATCAGGAGTTCGCTCAGCTCTTAGCACAGTCG GTGAACCATGGCTTTGAGACGGTGTATGAGCTTACCAAGATGTGCACTCTCCGCATGAGTTTTGTAAAGGGTTGGGGAG CTGAATATCATCGACAAGATGTAACGAGCACTCCATGCTGGATAGAGATACACCTTCACGGTCCCCTTCAGTGGCTGGA TAAAGTACTTACTCAGATGGGCTCTCCTCATAATCCTATTTCTTCAGTGTCTTAAGGTCCCAAGCTCCTGCATTTTGGA AACAATTGAGCCTTGCATGTACTTGAAGGACGTATGAGTCAGACACAGTTTTTTTCATTTTCCCCCCCACCCCGAACTG GCAACAGCTGAATAAGAGCCATGAAAATAATTTACTTCTGTGACCAACTGTTGGATTTGGGGAAAAAAACAACACAACA AAACAAAAAA
Citation	Le Dréau G, Garcia-Campmany L, Rabadán MA, Ferronha T, Tozer S, Briscoe J, Martí E. Canonical BMP7 activity is required for the generation of discrete neuronal populations in the dorsal spinal cord. Development. 2012 Jan;139(2):259-68.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_001201455.1).

Stage

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13-18

stage 18

Neural Plate/Tube
Spinal Ganglia and Nerves

19-24

stage 24

Neural Plate/Tube
Spinal Ganglia and Nerves

Entry 3

GEISHA Id	Smad1.Gont.2000	Data Source	Publication
Complete cDNA Template Probe	show GAATTCAAGCGCTACTTTCCCGGACTCTTTTCAGCAACCCAACAGTCACCCGTTCCCCCATTCGCCAAACAGCAGCTAT CCAAACTCGCCTGGAAGCAGCAGTAGCACCTACCCACATTCTCCAGCCAGCTCAGACCCAGGAAGCCCTTTTCAGATGC CAGCTGATACTCCTCCTCCTGCTTACCTGCCTCCGGAAGATCAGATGACACACGATACCTCCCAGCCAATGGATACCAA CATGATGGCACCCGGAATCCACCCTGACATACACAGAGGAGATGTTCAGGCTGTTGCTTATGAAGAGCCGAAGCATTGG TGCTCCATTGTTTATTACGAGCTGAATAATCGTGTTGGGGAGGCCTTCCATGCCTCTTCCACCAGCATCCTGGTGGATG GCTTCACTGATCCTTCAAACAACAAAAACAGATTTTGCCTGGGGCTGCTCTCCAATGTTAACCGGAATTCCACCATTGA GAATACAAGGAGGCACATTGGAAAAGGTGTTCATCTCTATTATGTTGGTGGAGAAGTGTACGCTGAATGCCTCAGCGAC AGCAGTATTTTTGTGCAAAGTCGAAACTGCAACTACCACCATGGTTTCCATCCAACCACAGTGTGCAAAATTCCCAGTG GCTGCAGTTTGAAGATTTTCAATAATCAGGAGTTCGCTCAGCTCTTAGCACAGTCGGTGAACCATGGCTTTGAGACGGT GTATGAGCTTACCAAGATGTGCACTCTCCGCATGAGTTTTGTAAAGGGTTGGGGAGCTGAATATCATCGACAAGATGTA ACGAGCACTCCATGCTGGATAGAGATACACCTTCACGGTCCCCTTCAGTGGCTGGATAAAGTACTTACTCAGATGGGCT CTCCTCATAATCCTATTTCTTCAGTGTCTTAAGGTCCCAAGCTCCTGCATTTTGGAAACAATTGAGCCTTGCATGTACT TGAAGGACGTATGAGTCAGACACAGTTTTTTTCATTTTCCCCCCCACCCCGAACTGTCAACAGCTGAATAAGAGCCATG AAAATAATTTACTTCTGTGACCAACTGTTGGATTTGGGGAAAAAAACAACACAACAAAACAAAAAACCAAAAACAAAAA ACAACCCCTTTGACATAATACTGTTGGTATCAAGTATCTTAGTTTACATAGTAACATTCTATTGCAAAGTTGATTTACA GGCCTTGTCATAAAGGAGGCTACTGAGCCAAAACAACAATCTCTTGGACTGAGTTCACGAAGGAGTTTCCTATAGTTGG CACTCTGAGATTCTCTTCCTTCTTGACATCCAGCACTCACTGCTTTTTTTCCCCCACGTTATCCTCTTGGGCTAAGAGC TGATGTTGGTGAAGCCTGCTTTTAGCAGGCTTTCTGCAGTATGTTTTAAAACCATTTGTTTAAGCTGATAGTTATTCTT CTCTTTATAAGACAAAAACCAACCAAACAAACAAAAAAACCAAACACCTAACATATAGTTTTAATATCAATATCTTGTA ATAATCTTGGAAATTGTGTCCTGACCATACTGCTGTAAGAATGTTAGGTATCTTTTTTGGTAAATGTATTTATGGTGTA TTTGGAAGCTTAGAAATCCTTTAGACGTAGACCCATAAAGGAATTAGGAGTATCTGAATGGGGGGAAGAGGGAGTGGGA AGAGATGATGACAACCGAAATGTAGAATATATTGTAAACATAGGTTGTTAGTTTAAACTGAGGTCTGAGTTTTGCTGTG CATTTCATTTTTATCGTGGCTTCACCTTGTTAATTCTGACTTTTTTTTGCCTCTTCCTTTTTCTCCCAGAGCAATTGCG CAGTTGGGTAATTCTTTTACCTGTGAAGAGGACGAAATGATTAATTCCTGCAGTTTGAAGGCTGCAGCTCTATGTATTT CAAGACAAAGTTGTACAGTGTGCTCTTTAACTATTGAGCAGTTTTATACAGTGTATGTAACAGAAATAGGCTTTTAATT TTGTAAGAGAGTCTTGTTTTGCCAAATCTAGAAACTGTTAATTGTTTGGAGGGCTTCAAAATCCCCATGTGGGTCTGTT TCAAACTTTTAAAAATATATATATTTTTAATTTTTTTTTACTGCTTGGTTTATTTTCTTCTCTTTGATCTTTTATATTC ATGTAAGCTGTAGTACTTTAAGTACCTTTATTCCAAACTTAGTGGGTCCTCTTTACTGGAAGTTTCGAATAAAACCTGT TGTTACTGCTTACATTTGATTAAAAAGCTT
Citation	Gont L, Lough J. Differential expression of cSmad1 and cSmad5 in the primitive streak during chick embryo gastrulation. Anat Rec. 2000 Sep 1;260(1):102-5.
Copyright	Copyright © 2000 Wiley‐Liss, Inc.
Comments	Authors indicated that 1781 nt antisense riboprobe was yielded through linearization with EcoRI of AF143239. As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence above was the whole sequence of NCBI acc# AF143239.