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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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HDAC2
histone deacetylase 2

Gene

Official Symbol	HDAC2
Official Full Name	histone deacetylase 2
CGNC ID	11140
also known as	histone deacetylase 2\|HD2
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_204831
Polypeptide	NP_990162
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.2951

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	3066	ENSG00000196591		MIM:605164
Mouse	15182	ENSMUSG00000019777	All phenotypic alleles (10):Targeted, knock-out(3) Targeted, other(6) Gene trapped(1)	MGI:1097691
Xenopus	447995, 399252			485806
Zebrafish

Gene Ontology

Molecular Function	histone deacetylase activity, NAD-dependent histone deacetylase activity (H3-K14 specific), more...
Biological Process	chromatin modification, regulation of transcription, DNA-templated, transcription, DNA-templated
Cellular Component	cytoplasm, ESC/E(Z) complex, histone deacetylase complex, nucleus

Links to other databases

Entrez Gene	395635
Ensembl Gene	ENSGALG00000014991
KEGG	gga:395635

Entry 1

GEISHA Id	HDAC2.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	TCATTGTCTGGTGATAGGTTGGG
Reverse cDNA Template Primer	ATTAACCCTCACTAAAGGTTTTGCTCCTTTGGTGTCCG	cDNA Template Length	648
Forward cDNA Template Probe	show CACTGTTGTCCTTGGGATTTATCCTCCTCCTTAACATCTGCTTTTTTGTCCTCTGGTCTCTTTCTTGTCTTCCTCTATC CTAGCTTTCTTTGCTCCTTTCTTGTGATCTGCAACATTTCGCCGTCCACCTTCCCCTTCATCTTCAGAGTCTGAAAACT CCTCATCACAGGCAATGCGCTTATCAGATGCTCGAATAGAAATGCGTTTGTCTGGATCTTCTCCATCCTCATCTCCACT ATCTTCATGAACAGCATCTTCAGGAATGGCCTGCATCTGTACACCAGGTGCATGAGGTAACATGCGCAAGTTTTCAAAT AAGCGTTGCTTGATCTTTTCCATATATTCTGGTGTATTCTGATTAGTCATATTTGATGGACTAATATGAAGTTTGAAGT CTGGTCCAAAATACTCAAAGTAATCATTGTATGGTAATTCATTAGGAATTTCACAATCTAAGGCAACAGCAGTTTCATA TGTCCAGCATCGAGCAACATTGCGAATAGTATATCCACCTCCTCCTAACATCAGCAATGGCAAGTTGAAGGTCTTTACA ACTTCCACACATTTTGCATGACCTTTAACAGTAAGATTAAAGCATCCCAACCTATCACA

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

4-6

stage 4

Area Pellucida
Primitive Streak

7-12

stage 8

stage 11

Endoderm
Extraembryonic
Forebrain
Hindbrain
Intermediate Mesoderm
Lateral Plate Mesoderm
Midbrain
Neural Plate/Tube
Notochord
Paraxial Mesoderm
Primitive Streak
Somites
Spinal Cord

13-18

stage 13

stage 14

stage 15

Anterior Intestinal Portal
Eye
Forebrain
Foregut
Head Mesenchyme
Hindbrain
Lateral Plate Mesoderm
Midbrain
Neural Plate/Tube
Notochord
Pharyngeal Arches and Clefts
Spinal Cord
Trunk Mesenchyme

19-23

stage 21

stage 23

Eye
Face Mesenchyme
Forebrain
Foregut
Gut
Heart
Hindbrain
Leg Mesenchyme
Midbrain
Pharyngeal Arches and Clefts
Sclerotome
Somites
Spinal Cord
Spinal Ganglia and Nerves
Trunk Mesenchyme
Wing Mesenchyme

Entry 2

GEISHA Id	HDAC2.Murko.2010	Data Source	Publication
Complete cDNA Template Probe	show GGCTCGATCTCGCCTCGGCCTCCCGTTCCCTCCTCCCCCTGCCCCGACTCGTCCCCGGCGCGGCGGCCCTATGGCGTAC AGTCAGGGCGGCGGCAAGAAGAAAGTCTGCTACTACTACGATGGTGATATTGGAAACTATTACTATGGACAAGGGCATC CAATGAAACCTCATAGGATCCGAATGACTCACAACTTGCTCCTAAATTATGGCTTGTACAGGAAAATGGAAATTTACCG ACCCCACAAAGCTACTGCTGAGGAAATGACCAAGTACCATAGTGATGAATACATCAAATTTCTCAGATCAATAAGGCCT GACAATATGTCTGAGTACAGCAAGCAGATGCAAAGATTTAATGTTGGAGAAGATTGTCCTGTATTTGATGGCCTGTTTG AGTTTTGTCAGCTGTCAACTGGAGGCTCTGTTGCTGGGGCGGTAAAATTGAACAGACAGCAGACAGACATGGCTGTTAA TTGGGCTGGAGGACTTCACCATGCCAAGAAGTCAGAGGCATCTGGTTTTTGTTATGTCAATGATATTGTGCTTGCCATC CTTGAGTTACTGAAGTATCACCAAAGAGTGTTGTATATTGATATTGATATCCATCATGGTGATGGTGTTGAAGAAGCAT TTTATACCACAGATCGTGTCATGACTGTGTCAGAGGTAAGTATGGTGAATAATTTTCCAGGCACAGGGGACCTTAGGGA CATTGGTGCTGGAAAAGGCAAATACTATGCTGTCAACTTTCCAATGAGGGATGGTATAGATGATGAGTCGTATGGACAG ATATTCAAACCAATTATATCAAAAGTAATGGAGATGTACCAGCCCAGTGCTGTAGTATTACAGTGTGGAGCAGATTCAT TGTCTGGTGATAGGTTGGGATGCTTTAATCTTACTGTTAAAGGTCATGCAAAATGTGTGGAAGTTGTAAAGACCTTCAA CTTGCCATTGCTGATGTTAGGAGGAGGTGGATATACTATTCGCAATGTTGCTCGATGCTGGACATATGAAACTGCTGTT GCCTTAGATTGTGAAATTCCTAATGAATTACCATACAATGATTACTTTGAGTATTTTGGACCAGACTTCAAACTTCATA TTAGTCCATCAAATATGACTAATCAGAATACACCAGAATATATGGAAAAGATCAAGCAACGCTTATTTGAAAACTTGCG CATGTTACCTCATGCACCTGGTGTACAGATGCAGGCCATTCCTGAAGATGCTGTTCATGAAGATAGTGGAGATGAGGAT GGAGAAGATCCAGACAAACGCATTTCTATTCGAGCATCTGATAAGCGCATTGCCTGTGATGAGGAGTTTTCAGACTCTG AAGATGAAGGGGAAGGTGGACGGCGAAATGTTGCAGATCACAAGAAAGGAGCAAAGAAAGCTAGGATAGAGGAAGACAA GAAAGAGACAGAGGACAAAAAAGCAGATGTTAAGGAGGAGGATAAATCCAAGGACAACAGTGGTGAAAAGACGGACACC AAAGGAGCAAAATCAGAACAGCTCAGCAATCCTTGAACAAAAGATAGCCTCACATCAATTGCAGAACATAATGCTAGAA TTGGAGAATACCTAAAGGAAGAAGTTTTCATATTGAGAAAGACTGCTGATTTCATTTTTGTACTATTTGGCATGGACCG TATCATTTTCAAACGGCTTTGTTCTGGTTTTGGCAAGTTGTATTGTGAGTTTCTAATCATGAGGCAGAAATTCCCTTCT TCACCATGCTTTATGTAATAGTATTTAAAATGGATGTGAGTTATGTTAAATGTCCAAACCGATCCATTAAAGTAAATTG CCTTTCCTGAGCTGATTTACCTTTTTGTAATTTTATCTTTATTAAAAAAAAAAAAAAAAAA
Citation	Murko C, Lagger S, Steiner M, Seiser C, Schoefer C, Pusch O. Expression of class I histone deacetylases during chick and mouse development. Int J Dev Biol. 2010;54(10):1527-37.
Copyright	Reprinted from Int. J. Dev. Biol., 55(1), Copyright (2010), with permission from the authors and IJDB

Stage

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Location (click to highlight)

Comments (click to highlight)

1-3

stage 1

7-12

stage 12

Ear/Otic Placode
Eye
Forebrain
Head Mesenchyme
Nephric Ducts

13-18

stage 14

Ear/Otic Placode
Head Mesenchyme
Nephric Ducts
Neural Plate/Tube
Notochord
Pharyngeal Arches and Clefts
Somites
Tail

19-24

stage 19

stage 24

Ear/Otic Placode
Eye
Forebrain
Head Mesenchyme
Leg
Limb Buds
Lung
Mesencephalon
Nasal Placode/Nerve
Neural Crest
Neural Plate/Tube
Notochord
Pharyngeal Arches and Clefts
Somites
Tail
Telencephalon
Wing

Entry 3

GEISHA Id	Hdac2.Zwane.2015	Data Source	GEISHA ISH Analysis
Complete cDNA Template Probe	show `ACAAGAAAGGAGCAAAGAAAGCTAGGATAGAGGAAGACAAGAAAGAGACAGAGGACAAAAAAGCAGATGTTAAGGAGGA GGATAAATCCAAGGACAACAGTGGTGAAAAGACGGACACCAAAGGAGCAAAATCAGAACAGCTCAGCAATCCTTGAACA AAAGATAGCCTCACATCAATTGCAGAACATAATGCTAGAATTGGAGAATACCTAAAGGAAGAAGTTTTCATATTGAGAA AGACTGCTGATTTCATTTTTGTACTATTTGGCATGGACCGTATCATTTTCAAACGGCTTTGTTCTGGTTTTGGCAAGTT GTATTGTGAGTTTCTAATCATGAGGCAGAAATTCCCTTCTTCACCATGCTTTATGTAATAGTATTTAAAATGGATGTGA GTTATGTTAAATGTCCAAACCGATCCATTAAAGTAAATTGCCTTTCCTGAGCTG`
Citation	Zwane TB, Nikitina NV. Spatiotemporal expression analysis of Prdm1 and Prdm1 binding partners in early chick embryo. Gene Expr Patterns. 2015 Jan;17(1):56-68. Epub 2015 Feb 17. DOI: 10.1016/j.gep.2014.12.003.
Copyright	Copyright © 2014 Elsevier B.V.
Comments	Authors indicated the probe was amplified by PCR using the following primers: 5'-ACAAGAAAGGAGCAAAGAAAGC-3' and 5'-CAGCTCAGGAAAGGCAAATTT-3'. Above sequence was extracted from NCBI accession number NM_204831.