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ID2 inhibitor of DNA binding 2, HLH protein Gene Summary Expression Transcript Levels Other Species Expression JBrowse Gene Official Symbol ID2 Official Full Name inhibitor of DNA binding 2, HLH protein CGNC ID 12279 also known as DNA-binding protein inhibitor ID-2|inhibitor of DNA binding 2, dominant negative helix-loop-helix protein|transcriptional regulator Id2 gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Gene Ontology Molecular Function Biological Process Cellular Component
Links to other databases
Entry 1 GEISHA Id D36 Data Source GEISHA ISH Analysis Complete cDNA Template Probe show GGGGAACGGCAGGCAGCGCGCTCCGCAGGCTCCGTGCGCTCTCCCCGCGCCCGCCTTTCAGCATGAAAGCTTTCAGCCC CGTGCGGTCCGTGCGGAAGAACGGCCTTTCGGAGCACAACCTGGGCATCTCCCGCAGCAAGACCCCGGTGGACGACCCC ATGAGCCTGCTGTACAACATGAACGACTGCTACTCCAAGCTGAAGGAGCTGGTGCCCAGCATCCCGCAGAACAAGAAGG TCAGCAAGATGGAAATCCTGCAGCACGTCATCGACTACATCCTGGACCTGCAGATCGCGCTGGACTCGCACCCGTCCAT CGTCAGCCTCCACCACCAGCGGCCGGGGCAGAACGCCGCCTCCCGGACCCCGCTGACCACGCTCAACACAGACATCAGC ATCCTCTCCCTACAGGCAGCCGAGTTCCCCTCAGAACTAATGGCGAGTGACAGCAAAGCGCTCTGTGGCTGAATCGCAC GGTGTTCCGCTGAGGAGGTTTTTCTTTTCCTTTTCTTGTTTTCTTCCTTTTTTTTTTTCTTTTTTTTTTTTTTTTTTGC ACAAGAATTACGTCCACAGGATTTGGGTTTTTGTCTTGAGGTGCTGAATTTCTCACCTGTACCTGGAGGGGAGGAATCC ACGCTAACTAAACTGAAAGGACCTTTAGAAACCAATAAAGAAGAGGAAAGAGGGGAAAAAAAAAAAATCATCGAGATTG CTCTTTATCCCCCCACCCCGTTCTTCAAGTTGGACTGAACCTAGTTATTTATGAAGAGACTCTTTAAATACCCTTTCCC TAGTCGGAAGGCTTCCTTTATATACTATTCCCAACATGGGGAGCGAAACAAAATCACACGCGGAGTTGCCCATTTTAAA GCAGACTTTGCCTTTTCTTCCAAAGGTGGAGCGTGAGTACCAGAAGGACCCGGCGTTCAGTTCTTTAGGGGAGTCCGGG GTCAGAAATTGCCTTTCTGACCCAAGCCTAGGACTGAATGCTGTGTATATATTTATATATAAATATATATATATGAGTG AACCCTTGTGAACTCTTTAATTAGAGTTTTCTTGTATAGTGGCAGAAATGGACGTTTCTGCAAAAAGTGTAATGATGTA CTTAATCATGCTAAACTTTTTATAAAAGTTTAGTTGTAAACTTAACCCCTTTTTATACAAAAATAAATCGAGTGTGTTT ATGAAAAAAAAAAAAAAAAAA
Entry 2 GEISHA Id Id2.Martinsen.2004 Data Source Publication Complete cDNA Template Probe show AATTCCGCCGAGAGGGGAACGGCAGGCAGCGCGCTCCGCAGGCTCCGTGCGCTCTCCCCGCGCCCGCCTTTCAGCATGA AAGCTTTCAGCCCCGTGCGGTCCGTGCGGAAGAACGGCCTTTCGGAGCACAACCTGGGCATCTCCCGCAGCAAGACCCC GGTGGACGACCCCATGAGCCTGCTGTACAACATGAACGACTGCTACTCCAAGCTGAAGGAGCTGGTGCCCAGCATCCCG CAGAACAAGAAGGTCAGCAAGATGGAAATCCTGCAGCACGTCATCGACTACATCCTGGACCTGCAGATCGCGCTGGACT CGCACCCGTCCATCGTCAGCCTCCACCACCAGCGGCCGGGGCAGAACGCCGCCTCCCGGACCCCGCTGACCACGCTCAA CACAGACATCAGCATCCTCTCCCTACAGGCAGCCGAGTTCCCCTCAGAACTAATGGCGAGTGACAGCAAAGCGCTCTGT GGCTGAATCGCACGGTGTTCCGCTGAGGAGGTTTTTCTTTTCCTTTTCTTGTTTTCTTCTTTTTTTTTCTTTTCTTTTT TTTTTTTTTTTGCACAAGAATTACGTCGACAGGATTTGGGTTTTTGTCTTGAGGTGCTGAATTTCTCAGCTGTACCTGG AGGGGAGGAATCCACGCTAACTAAACTGAAAGGACCTTTAGAAACGAATAGAGAAGAGGAAAGAGGGGAAAAAAAAATC ATCGAGATTGCTCTTTATCCCCCCACCCCGTTCTTCAAGTTGGACTGAACCTAGTTATTTATGAAGAGACTCTTTAAAT ACCCTTTCCCTAGTCGGAAGGCTTCCTTTATATACTATTCCCAACATGGGGAGCGAAACAAAATCACACGCGGAGTTGC CCATTTTAAAGCAGACTTTGCCTTTTCTTCCAAAGGTGGAGCGTGAGTACCAGAAGGACCCGGCGTTCAGTTCTTTAGG GGAGTCCGGGGTCAGAAATTGCCTTTCTGACCCAAGCCTAGGACTGAATGCTGTGTATATATTTATATATAAATATATA TATATGAGTGAACCCTTGTGAACTCTTTAATTAGAGTTTTCTTGTATAGTGGCAGAAATGGACGTTTCTGCAAAAAGTG TAATGATGTACTTAATCATGCTAAACTTTTTATAAAAGTTTAGTTGTAAACTTAACCCCTTTTTATACAAAAATAAATC GAGTGTGTTTATTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Citation Martinsen BJ, Frasier AJ, Baker CV, Lohr JL. Cardiac neural crest ablation alters Id2 gene expression in the developing heart. Dev Biol. 2004 Aug 1;272(1):176-90. Copyright Reprinted from Developmental Biology, Volume 272, Issue 1, Brad J Martinsen, Allison J Frasier, Clare V.H Baker, and Jamie L Lohr, Cardiac neural crest ablation alters Id2 gene expression in the developing heart, Pages 176-190, Copyright 2004, with permission from Elsevier.
Copyright © 2004 Elsevier B.V. All rights reserved. Comments Authors said: A linearized plasmid of chick Id2 (either full length or from nucleotide 554 to 848) was used as a template to generate a digoxigenin-labeled antisense probe (Martinsen and Bronner-Fraser, 1998). Probe sequence used was from Acc# NM_205002.1)
Entry 3 Entry 4 GEISHA Id ID2.Olivera-Martinez.2014 Data Source Publication Complete cDNA Template Probe show AATTCCGCCGAGAGGGGAACGGCAGGCAGCGCGCTCCGCAGGCTCCGTGCGCTCTCCCCGCGCCCGCCTTTCAGCATGA AAGCTTTCAGCCCCGTGCGGTCCGTGCGGAAGAACGGCCTTTCGGAGCACAACCTGGGCATCTCCCGCAGCAAGACCCC GGTGGACGACCCCATGAGCCTGCTGTACAACATGAACGACTGCTACTCCAAGCTGAAGGAGCTGGTGCCCAGCATCCCG CAGAACAAGAAGGTCAGCAAGATGGAAATCCTGCAGCACGTCATCGACTACATCCTGGACCTGCAGATCGCGCTGGACT CGCACCCGTCCATCGTCAGCCTCCACCACCAGCGGCCGGGGCAGAACGCCGCCTCCCGGACCCCGCTGACCACGCTCAA CACAGACATCAGCATCCTCTCCCTACAGGCAGCCGAGTTCCCCTCAGAACTAATGGCGAGTGACAGCAAAGCGCTCTGT GGCTGAATCGCACGGTGTTCCGCTGAGGAGGTTTTTCTTTTCCTTTTCTTGTTTTCTTCTTTTTTTTTCTTTTCTTTTT TTTTTTTTTTTGCACAAGAATTACGTCGACAGGATTTGGGTTTTTGTCTTGAGGTGCTGAATTTCTCAGCTGTACCTGG AGGGGAGGAATCCACGCTAACTAAACTGAAAGGACCTTTAGAAACGAATAGAGAAGAGGAAAGAGGGGAAAAAAAAATC ATCGAGATTGCTCTTTATCCCCCCACCCCGTTCTTCAAGTTGGACTGAACCTAGTTATTTATGAAGAGACTCTTTAAAT ACCCTTTCCCTAGTCGGAAGGCTTCCTTTATATACTATTCCCAACATGGGGAGCGAAACAAAATCACACGCGGAGTTGC CCATTTTAAAGCAGACTTTGCCTTTTCTTCCAAAGGTGGAGCGTGAGTACCAGAAGGACCCGGCGTTCAGTTCTTTAGG GGAGTCCGGGGTCAGAAATTGCCTTTCTGACCCAAGCCTAGGACTGAATGCTGTGTATATATTTATATATAAATATATA TATATGAGTGAACCCTTGTGAACTCTTTAATTAGAGTTTTCTTGTATAGTGGCAGAAATGGACGTTTCTGCAAAAAGTG TAATGATGTACTTAATCATGCTAAACTTTTTATAAAAGTTTAGTTGTAAACTTAACCCCTTTTTATACAAAAATAAATC GAGTGTGTTTATTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Citation Isabel Olivera-Martinez, Nick Schurch, Roman A Li, Junfang Song, Pamela A Halley, Raman M Das, Dave W Burt, Geoffrey J Barton, Kate G Storey. Major transcriptome re-organisation and abrupt changes in signalling, cell cycle and chromatin regulation at neural differentiation in vivo. Development 2014 Aug;141(16):3266-76. Epub 2014 Jul 25. DOI: 10.1242/dev.112623. Copyright Copyright © 2014. Published by The Company of Biologists Ltd. Comments Authors indicated the probe was made from gene construct provided by M. Bronner. As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence above was obtained from NCBI (accession number NM_205002.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-10 stage 10
Neural Plate/Tube Somites all
Entry 5 GEISHA Id ID2.Anderson.2021 Data Source Direct Submission Complete cDNA Template Probe show AGTGCGAGCTCCGGCGGCGCCGAGAGGGGAACGGCAGGCAGCGCGCTCCGCAGGCTCCGTGCGCTCTCCCCGCGCCCGC CTTTCAGCATGAAAGCTTTCAGCCCCGTGCGGTCCGTGCGGAAGAACGGCCTTTCGGAGCACAACCTGGGCATCTCCCG CAGCAAGACCCCGGTGGACGACCCCATGAGCCTGCTGTACAACATGAACGACTGCTACTCCAAGCTGAAGGAGCTGGTG CCCAGCATCCCGCAGAACAAGAAGGTCAGCAAGATGGAAATCCTGCAGCACGTCATCGACTACATCCTGGACCTGCAGA TCGCGCTGGACTCGCACCCGTCCATCGTCAGCCTCCACCACCAGCGGCCGGGGCAGAACGCCGCCTCCCGGACCCCGCT GACCACGCTCAACACAGACATCAGCATCCTCTCCCTACAGGCAGCCGAGTTCCCCTCAGAACTAATGGCGAGTGACAGC AAAGCGCTCTGTGGCTGAATCGCACGGTGTTCCGCTGAGGAGGTTTTTCTTTTCCTTTTCTTGTTTTCTTCTTTTTTTT TTTTCTTTTTTTTTTTTTTTTTTGCACAAGAATTACGTCGACAGGATTTGGGTTTTTGTCTTGAGGTGCTGAATTTCTC AGCTGTACCTGGAGGGGAGGAATCCACGCTAACTAAACTGAAAGGACCTTTAGAAACGAATAGAGAAGAGGAAAGAGGG GAAAAAAAAAAATCATCGAGATTGCTCTTTATCCCCCCACCCCGTTCTTCAAGTTGGACTGAACCTAGTTATTTATGAA GAGACTCTTTAAATACCCTTTCCCTAGTCGGAAGGCTTCCTTTATATACTATTCCCAACATGGGGAGCGAAACAAAATC ACACGCGGAGTTGCCCATTTTAAAGCAGACTTTGCCTTTTCTTCCAAAGGTGGAGCGTGAGTACCAGAAGGACCCGGCG TTCAGTTCTTTAGGGGAGTCCGGGGTCAGAAATTGCCTTTCTGACCCAAGCCTAGGACTGAATGCTGTGTATATATTTA TATATAAATATATATATATGAGTGAACCCTTGTGAACTCTTTAATTAGAGTTTTCTTGTATAGTGGCAGAAATGGACGT TTCTGCAAAAAGTGTAATGATGTACTTAATCATGCTAAACTTTTTATAAAAGTTTAGTTGTAAACTTAACCCCTTTTTA TACAAAAATAAATCGAGTGTGTTTATTGAACCGATTGCTGGCTTTCTTCTTTGGGGGACCAACTGTTTGCTGGCTCTGA TTTGTGCTGTTTGTGGTTTTTATTTTGTCTTTTAAATACTTTAAGCCTTCTGTTACGATTTACTGAGCAAGTTTAAACG TGTAGAGAATATAAAGAATAAAATGACCTGAAGTGAATCATAA
Comments Images provided by Claire Anderson. As insufficient information was provided to verify sequence used to synthesize probe, the sequence above was obtained from NCBI (accession number NM_205002.2). Reference paper: Anderson C, Khan MAF, Wong F, Solovieva T, Oliveira NMM, Baldock RA, Tickle C, Burt DW, Stern CD. A strategy to discover new organizers identifies a putative heart organizer. Nat Commun. 2016 7:12656. doi: 10.1038/ncomms12656.
Entry 6 GEISHA Id ID2.Trevers.2023 Data Source GEISHA ISH Analysis Complete cDNA Template Probe show AGTGCGAGCTCCGGCGGCGCCGAGAGGGGAACGGCAGGCAGCGCGCTCCGCAGGCTCCGTGCGCTCTCCCCGCGCCCGC CTTTCAGCATGAAAGCTTTCAGCCCCGTGCGGTCCGTGCGGAAGAACGGCCTTTCGGAGCACAACCTGGGCATCTCCCG CAGCAAGACCCCGGTGGACGACCCCATGAGCCTGCTGTACAACATGAACGACTGCTACTCCAAGCTGAAGGAGCTGGTG CCCAGCATCCCGCAGAACAAGAAGGTCAGCAAGATGGAAATCCTGCAGCACGTCATCGACTACATCCTGGACCTGCAGA TCGCGCTGGACTCGCACCCGTCCATCGTCAGCCTCCACCACCAGCGGCCGGGGCAGAACGCCGCCTCCCGGACCCCGCT GACCACGCTCAACACAGACATCAGCATCCTCTCCCTACAGGCAGCCGAGTTCCCCTCAGAACTAATGGCGAGTGACAGC AAAGCGCTCTGTGGCTGAATCGCACGGTGTTCCGCTGAGGAGGTTTTTCTTTTCCTTTTCTTGTTTTCTTCTTTTTTTT TTTTCTTTTTTTTTTTTTTTTTTGCACAAGAATTACGTCGACAGGATTTGGGTTTTTGTCTTGAGGTGCTGAATTTCTC AGCTGTACCTGGAGGGGAGGAATCCACGCTAACTAAACTGAAAGGACCTTTAGAAACGAATAGAGAAGAGGAAAGAGGG GAAAAAAAAAAATCATCGAGATTGCTCTTTATCCCCCCACCCCGTTCTTCAAGTTGGACTGAACCTAGTTATTTATGAA GAGACTCTTTAAATACCCTTTCCCTAGTCGGAAGGCTTCCTTTATATACTATTCCCAACATGGGGAGCGAAACAAAATC ACACGCGGAGTTGCCCATTTTAAAGCAGACTTTGCCTTTTCTTCCAAAGGTGGAGCGTGAGTACCAGAAGGACCCGGCG TTCAGTTCTTTAGGGGAGTCCGGGGTCAGAAATTGCCTTTCTGACCCAAGCCTAGGACTGAATGCTGTGTATATATTTA TATATAAATATATATATATGAGTGAACCCTTGTGAACTCTTTAATTAGAGTTTTCTTGTATAGTGGCAGAAATGGACGT TTCTGCAAAAAGTGTAATGATGTACTTAATCATGCTAAACTTTTTATAAAAGTTTAGTTGTAAACTTAACCCCTTTTTA TACAAAAATAAATCGAGTGTGTTTATTGAACCGATTGCTGGCTTTCTTCTTTGGGGGACCAACTGTTTGCTGGCTCTGA TTTGTGCTGTTTGTGGTTTTTATTTTGTCTTTTAAATACTTTAAGCCTTCTGTTACGATTTACTGAGCAAGTTTAAACG TGTAGAGAATATAAAGAATAAAATGACCTGAAGTGAATCATAA
Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205002).
Data from NCBI Unigene EST Profile Unigene ID: Gga.3125
Mouse Frog Fruit Fly Zebra Finch Zebrafish