GEISHA - A Chicken Embryo Gene Expression Database
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CLOCK
clock circadian regulator

Gene
Official SymbolCLOCK
Official Full Nameclock circadian regulator
CGNC ID10328
also known ascircadian locomoter output cycles protein kaput|clock homolog|transcription regulation factor
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
UCSC
Sequence Information
Genomic
RNANM_204174
PolypeptideNP_989505
Gene Expression
In Situ HybridizationGEISHA
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly38872FBgn0023076
Human9575ENSG00000134852MIM:601851
Mouse12753ENSMUSG00000029238All phenotypic alleles (4):Chemically induced(1) Targeted, knock-out(2) Targeted, other(1) MGI:99698
Xenopus100038163, 399157495447
Zebrafish352927, 30140ENSDARG00000003631, ENSDARG00000011703ZDB-GENE-030408-2, ZDB-GENE-990630-14ZFIN:ZDB-GENE-030408-2, ZFIN:ZDB-GENE-990630-14
Gene Ontology
Molecular FunctionDNA binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity, more...signal transducer activity
Biological Processcellular response to DNA damage stimulus, rhythmic process, transcription, DNA-templated
Cellular Componentchromosome, cytoplasm, nucleus, transcription factor complex
Links to other databases
Entrez Gene373991
Ensembl Gene
KEGGgga:373991

Entry 1

GEISHA IdCLOCK.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template PrimerTTATAAAAGCTTGCGGCCGCAGAATATTCTTCTCATCTGCTGGAAAGCG
Reverse cDNA Template PrimerGCTCTAGAAATTAACCCTCACTAAAGGCCACTGTCATTTTAGTTGGTGTCGcDNA Template Length920
Complete cDNA Template Probeshow
TTTTTTAAAAAGCTGGGGCCGCAGAATATTCTTCTCATCTGCTGGAAAGCGATTCATTGGACACCGCGAATACTTAAAA
TCAAAAAATCAGCTAGAATTCTGTTGCCATATGCTGCGAGGAACAATAGACCCCAAAAGAGCAACCTACGTATGAATAT
GTAAAATTTATAGGCAATTTCAAGTGTTTGAATAATGTTCCCAATTCGGCACACAACGGTTTTGAAGGAACTATTCAGC
GGTCGCACCGGCCTTCATATGAAGACAAAGTTTGCTTTATAGCCACAGTTAGATTAGCTACACCTCAATTTATCAAGGA
AATGTGCACTGTTGAAGAACCCAATGAAGAGTTCACATCTAGGCATAGCTTAGAATGGAAGTTCCTATTCTTGGATCAC
AGGGCACCTCCAATAATAGGCTATCTTCCATTTGAAGTTTTGGGAACATCAGGCTATGATTATTATCATGTGGATGATC
TAGATAATCTGGCAAAATGTCATGAGCATTTAATGCAATATGGGAAAGGGAAGTCATGTTATTACAGATTCCTTACAAA
GGGACAGCAATGGATTTGGCTGCAAACACATTACTATATCACGTACCACCAGTGGAATTCCAGGCCAGAGTTTATTGTC
TGTACGCACACAGTTGTAAGTTATGCAGAAGTCAGAGCAGAAAGGCGGCGAGAACTTGGTATTGAGGAGTCTCTGCCAG
AGATAAAAGCAGATAAAAGTCAAGACTCTGGGTCGATAATCACATCAACACGGTGAGCCTCAAAGAAGCTCTGGAAAGG
TTTGATACCAGCCCCACACCCTTCTGCTTCCTCCAGGAGTTCAAGAAAATCTTCACCATAGCTGCCAGTATCCAGATCC
ATTCATCGACACCAACTAAAATGACAGTGGCCTTTAGTGAGGGTTATTTTC
CommentsNo expression detected for stages 3-25.
no images

Entry 2

GEISHA IdCLOCK.Goncalves.2012Data SourcePublication
Complete cDNA Template Probeshow
CACAGAACTGACAAGATGACGGATCCTTCCAAAGCTCAGCCACAGTAGCTGGGGGCTCTGCCTCTCTGGGAAGTCAGCT
ACCGGGAGGGGGCTGCTCCATAACCACTTGCACTGAAGTTGCAGAGGTAGCAGTACAAAGCCTTTCTAACGCCACGGTA
TTGAGACCTACAGCTAACTTCTGGAATCTGTTAAGGAAAACCACCAGGTGATGGCAGGGACGTGGCCAACTTTGACGTG
TCCCGGTTTCTGTGCTCTAAAGGGTTTGCTGCCATGTGTTAATTTGCCAGGTGAAATCAAAAAATGTGACTGAAATGAG
AGGGATGCTGAAAATATTGGTATTTTTTATCAGTTCTGTACATTTTTAAAGTACTAAAATGGACACAGAGCAATTGTTT
GATTTAGCAGAAAAAAAATGCCAGGAATATAGCCCGACAAACATCTAATTTTTTCAGATGATTATGGGACAGTAAATAT
TTTGAAAATGTTGTGGGAAATCCAGTTCTCTGTTGTAC
CitationGonçalves L, Vinhas M, Pereira R, Pais De Azevedo T, Bajanca F, Palmeirim I. Circadian clock genes Bmal1 and Clock during early chick development. Dev Dyn. 2012 Aug;241(8):1365-73. doi: 10.1002/dvdy.23821.
CopyrightCopyright © 2012 Wiley Periodicals, Inc.
CommentsThe complete cDNA template sequence used to generate the probe was obtained by PCR as described Goncalves et al. 2012.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 4
stage 4
stage 4
stage 4
stage 5
stage 5
Epiblast
Hensen's Node
Hypoblast
Primitive Streak
BMAL1(blue)
CLOCK(red)
double-labeled in situ:
sections of Fig. 4B whole-mount
7-12
stage 7
stage 7
stage 7
stage 9
stage 10
stage 10
stage 10
stage 10
stage 11
stage 11
stage 11
stage 12
stage 12
stage 12
stage 12
Ectoderm
Eye
Forebrain
Foregut
Head Mesenchyme
Head Process
Headfold
Heart
Hensen's Node
Hindbrain
Hypoblast
Lateral Plate Mesoderm
Midbrain
Neural Plate/Tube
Notochord
Primitive Streak
Somites
BMAL1(blue)
CLOCK(red)
Double-labeled in situ:
Stage 11 + Embryo
Stage 11+ Embryo
double-labeled in situ:
sections of Fig. 4C whole-mount
sections of Fig. 4D whole-mount
sections of Fig. 5 A,A' whole-mount
stage 9+ embryo
13
stage 13
stage 13
Central Nervous System
Head Process
Heart
Neural Plate/Tube
Somites
Tail
Stage 13- embryo

Mouse

EmageMGI:99698
MGI GXDMGI:99698

Frog

Xenbase495447

Fruit Fly

BDGPFBgn0023076

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-030408-2, ZDB-GENE-990630-14
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