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A chicken embryo gene expression database

	Anatomical Location
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	Gene Name
	GEISHA ID
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KERA
keratocan

The human orthologue of this gene is associated
with the following human disease:

Cornea plana congenita, recessive

Gene

Official Symbol	KERA
Official Full Name	keratocan
CGNC ID	48995
also known as	keratocan\|KTN\|keratan sulfate proteoglycan keratocan
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC

Sequence Information

Genomic
RNA	NM_204176
Polypeptide	NP_989507

Gene Expression

In Situ Hybridization

GEISHA

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	11081	ENSG00000139330	MIM:217300	MIM:603288
Mouse	16545	ENSMUSG00000019932	All phenotypic alleles (4):Targeted, knock-out(2) Targeted, other(2)	MGI:1202398
Xenopus	100486796			1012701
Zebrafish	567017		ZDB-GENE-041210-165	ZFIN:ZDB-GENE-041210-165

Gene Ontology

Molecular Function
Biological Process	cornea development in camera-type eye
Cellular Component	proteinaceous extracellular matrix

Links to other databases

Entrez Gene	373995
Ensembl Gene	ENSGALG00000011270
KEGG	gga:373995

Entry 1

GEISHA Id	KERA.Conrad.2009	Data Source	Publication
Complete cDNA Template Probe	show CATTCTGTGTGGACTCGAACTGTGAGACAAGTTTATAATGAGCTGGATCCTGAGCATTGGTCTCACTACACTTTTGAGT GTCCACAAGAGTGTTTTTGCCCTCCTAGTTTCCCCAATGCATTATACTGTGATAACAAAGGACTTAAAGAAATACCTGC AATCCCAGCAAGAATTTGGTACCTCTATCTTCAAAACAACCTGATTGAAACAATTTCAGAGAAGCCTTTTGTTAATGCC ACTCATTTGAGATGGATAAATCTGAACAAGAATAAAATCACCAACAATGGAATTGAGAGTGGTGTGCTCAGCAAGCTGA AAAGGCTGTTGTACTTATTCCTTGAAGATAATGAGTTGGAAGAGGTGCCAGCTCCATTACCGGTGGGCTTGGAACAGCT AAGGCTGGCTAGAAACAAAATCTCCAGAATCCCAGAAGGAGTCTTCAGCAATTTGGAAAATCTCACTATGTTAGATCTG CACCAGAATAATTTGTTGGACAGCGCTCTTCAAAGTGACACCTTCCAAGGACTCAACAGTCTTATGCAACTCAACATAG CGAAAAATTCCCTCAAAAAGATGCCTTTAAGCATTCCAGCTAACACACTGCAGCTGTTTTTAGACAACAACTCCATTGA AGTCATACCAGAAAACTACTTCAGTGCAATACCCAAAGTGACTTTCCTTAGGCTGAACTACAATAAATTATCTGATGAT GGCATTCCCCCAAATGGGTTTAATGTTTCATCTATTCTAGACCTACAGCTGTCTCATAACCAGCTCACTAAAATTCCAC CGATCAATGCTCATCTCGAGCACCTTCACCTTGATCACA
Citation	Conrad AH, Albrecht M, Pettit-Scott M, Conrad GW. Embryonic corneal Schwann cells express some Schwann cell marker mRNAs, but no mature Schwann cell marker proteins.Invest Ophthalmol Vis Sci. 2009 Sep;50(9):4173-84. Epub 2009 Apr 22.
Copyright	Information that is created by or for the US government on this site is within the public domain. Public domain information on the National Library of Medicine (NLM) Web pages may be freely distributed and copied. However, it is requested that in any subsequent use of this work, NLM be given appropriate acknowledgment.
Comments	The probe for KERA was amplified by PCR using the following primers: forward primer: 5;-AGTCCATTCTGTGTGGACTCG reverse primer: 5;-TGTGATCAAGGTGAAGGTGC

Stage

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Location (click to highlight)

Comments (click to highlight)

31-40

stage 40

Eye

Entry 2

GEISHA Id	KERA.Chakravarti.2006	Data Source	Publication
Complete cDNA Template Probe	show AGTCCATTCTGTGTGGACTCGAACTGTGAGACAAGTTTATAATGAGCTGGATCCTGAGCATTGGTCTCACTACACTTTT GAGTGTCCACAAGAGTGTTTTTGCCCTCCTAGTTTCCCCAATGCATTATACTGTGATAACAAAGGACTTAAAGAAATAC CTGCAATCCCAGCAAGAATTTGGTACCTCTATCTTCAAAACAACCTGATTGAAACAATTTCAGAGAAGCCTTTTGTTAA TGCCACTCATTTGAGATGGATAAATCTGAACAAGAATAAAATCACCAACAATGGAATTGAGAGTGGTGTGCTCAGCAAG CTGAAAAGGCTGTTGTACTTATTCCTTGAAGATAATGAGTTGGAAGAGGTGCCAGCTCCATTACCGGTGGGCTTGGAAC AGCTAAGGCTGGCTAGAAACAAAATCTCCAGAATCCCAGAAGGAGTCTTCAGCAATTTGGAAAATCTCACTATGTTAGA TCTGCACCAGAATAATTTGTTGGACAGCGCTCTTCAAAGTGACACCTTCCAAGGACTCAACAGTCTTATGCAACTCAAC ATAGCGAAAAATTCCCTCAAAAAGATGCCTTTAAGCATTCCAGCTAACACACTGCAGCTGTTTTTAGACAACAACTCCA TTGAAGTCATACCAGAAAACTACTTCAGTGCAATACCCAAAGTGACTTTCCTTAGGCTGAACTACAATAAATTATCTGA TGATGGCATTCCCCCAAATGGGTTTAATGTTTCATCTATTCTAGACCTACAGCTGTCTCATAACCAGCTCACTAAAATT CCACCGATCAATGCTCATCTCGAGCACCTTCACCTTGATCACA
Citation	Chakravarti S. Focus on molecules: keratocan (KERA). Exp Eye Res. 2006 Feb;82(2):183-4.
Copyright	Copyright © 2005 Elsevier Ltd.
Comments	The complete cDNA template sequence was obtained from the information from the publication as described in Chakravarti et al. 2006.