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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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TBX5
T-box 5

The human orthologue of this gene is associated
with the following human disease:

Holt-Oram syndrome

Gene

Official Symbol	TBX5
Official Full Name	T-box 5
CGNC ID	6251
also known as	T-box transcription factor TBX5\|T-box protein 5, TBX5, TBX-5, T-box transcription factor TBX5
gene type	protein-coding

Genomic Map

	Ensembl ID not known
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic	Genbank
RNA	NM_204173
Polypeptide	NP_989504
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.961

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	6910	ENSG00000089225	MIM:142900	MIM:601620
Mouse	21388	ENSMUSG00000018263	All phenotypic alleles (3):Targeted, knock-out(1) Targeted, other(2)	MGI:102541
Xenopus	619589, 373738, 373556			486854
Zebrafish	30071, 100004161	ENSDARG00000024894, ENSDARG00000092060	ZDB-GENE-991124-7, ZDB-GENE-060601-2	ZFIN:ZDB-GENE-991124-7, ZFIN:ZDB-GENE-060601-2

Gene Ontology

Molecular Function	DNA binding, protein binding, RNA polymerase II regulatory region sequence-specific DNA binding, more...
Biological Process	apoptotic nuclear changes, atrial septum morphogenesis, atrioventricular valve morphogenesis, more...
Cellular Component	cytoplasm, nucleus, transcription factor complex

Links to other databases

Entrez Gene	373988
Ensembl Gene
KEGG	gga:373988

Entry 1

GEISHA Id	ChEST59k10	Data Source	GEISHA ISH Analysis
Forward cDNA Template Probe	show GCCACAGGACGGCTGTTTACCCTGCGCTGACCTATTCAACTTTACCCTCAAAATAATACATTAAAAAGAGAGCGAGAAG GGAGAGGAGGAAGAGGCAGATAAAACCACGTCCCCGCTCCTCGCTGACGGTTTGATTATTTGAGCAGAGCGGAGGCTGC GGGGTTGCGTACCCCAGCCGGGCAGCGCGTGGGGGATTCGGCGAAGGAAGCTCGTAACATGGCGGACACCGAGGAAGGC TTCGGGCTCCCGAGCACGCCGGTTGACTCGGAGGCCAAGGAGCTGCAGGCTGAGGCCAAGCAGGATCCCCAGCTGGGGA CCACCAGCAAGGCCCCCACCTCTCCACAGGCGGCCTTCACCCAGCAGGGCATGGAGGGGATCAAAGTGTTTTTGCACGA GCGGGAGCTGTGGCTGAAATTTCACGAGGTGGGGACGGAGATGATCATAACAAAGGCTGGAAGGCGTATGTTTCCCAGT TACAAAGTGAAGGTCACTGGACTCAATCCAAAAACGAAGTACATACTGTTGATGGATATTGTACCAGCGGATGACCACA GATACAAATTTGCAGATAATAAATGGTCCGTGACCGGGAAGGCAGAACCGGCCATGCCCGGCCGCCTCTACGTGCACCC CGACTCCCCCGCTACTGGAGCCCACTGGATGAGGCAGTTGGTTTCCTTCCAGAAGCTCAAGCTCACCAACAACCACCTT GACCCCTTCGGACATATCATCCTGAACTCCATGCACAAATACCAGCCCCGGCTCCACATCGTGAAGGCGGGATGAGAAC ACGGCTTTGGCTCCAAGAACACTGCCTTCTGCACCCATGTCTTCCCCGAGACTGCCTTCATCGCTGTTACCTCCTACCA AAACCACAAGAGATGTAAGGGGGAAGCTACTTAACGTGCATGAAATGGTCGCGTTTTCTCTATCCATCGGTTGGGCCGG GAGCTGCAAAAACGGAAGTAGGCTTGAAAAAAAAAAATGT

Stage

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Location (click to highlight)

Comments (click to highlight)

4-6

stage 4

stage 6

Early Mesoderm
Primitive Streak
Splanchnic Mesoderm

7-12

stage 10

stage 11

stage 12

Atria
Heart Tube
Sinus Venosus
Telencephalon
Ventricles

13-18

stage 13

stage 14

stage 17

stage 18

Allantois
Atria
Eye
Heart Tube
Lateral Plate Mesoderm
Retina
Sinus Venosus
Somatopleure
Telencephalon
Ventricles
Wing
Wing Mesenchyme

19-22

stage 19

stage 20

stage 22

Allantois
Atria
Eye
Retina
Somatopleure
Splanchnic Mesoderm
Ventricles
Wing Mesenchyme

hand transected

Entry 2

GEISHA Id	Tbx5.Plageman.2005	Data Source	Publication
Complete cDNA Template Probe	show CGGGGGGCTGCCGCCATGCGGCCCCACGGTGCGGGGGTTCCTCCGGGCAGGAAGGCGGGGGCCGACCCTGCTGTCCGCA TCGCAGCGAGGAGCCGCAGCCACGCACCCCCCCGCACGCGCAGTGGGGGATTCGGCGAAGGAAGCTCGTAACATGGCGG ACACCGAGGAAGGCTTCGGGCTCCCGAGCACGCCGGTTGACTCGGAGGCCAAGGAGCTGCAGGCTGAGGCCAAGCAGGA TCCCCAGCTGGGGACCACCAGCAAGGCCCCCACCTCTCCACAGGCGGCCTTCACCCAGCAGGGCATGGAGGGGATCAAA GTGTTTTTGCACGAGCGGGAGCTGTGGCTGAAATTTCACGAGGTGGGGACGGAGATGATCATAACAAAGGCTGGAAGGC GTATGTTTCCCAGTTACAAAGTGAAGGTCACTGGACTCAATCCAAAAACGAAGTACATACTGTTGATGGATATTGTACC AGCGGATGACCACAGATACAAATTTGCAGATAATAAATGGTCCGTGACCGGGAAGGCAGAACCGGCCATGCCCGGCCGC CTCTACGTGCACCCCGACTCCCCCGCTACTGGAGCCCACTGGATGAGGCAGTTGGTTTCCTTCCAGAAGCTCAAGCTCA CCAACAACCACCTTGACCCCTTCGGACATATCATCCTGAACTCCATGCACAAATACCAGCCCCGGCTCCACATCGTGAA GGCGGATGAGAACAACGGCTTTGGCTCCAAGAACACTGCCTTCTGCACCCATGTCTTCCCCGAGACTGCCTTCATCGCT GTTACCTCCTACCAAAACCACAAGATCACTCAGCTGAAGATTGAGAACAACCCCTTCGCAAAAGGTTTCCGCGGCAGCG ATGACATGGAGCTCCACAGGATGTCCAGGATGCAGAGTAAAGAGTACCCAGTTGTTCCCAGGAGCACAGTGAGACAGAA AGTGTCCTCGAATCACAGCCCCTTCAGCGGTGAGACCAGGGTCCTTTCCACCTCCTCCAACCTGGGCTCCCAGTACCAG TGTGAGAACGGGGTGTCAAGCACCTCCCAGGACCTGCTGCCGCCCACCAACCCCTACCCGATCTCCCAGGAGCACAGCC AGATCTACCACTGCACCAAGAGAAAAGATGAGGAATGTTCCACCACCGAGCATCCCTACAAGAAGCCCTACATGGAAAC TTCACCAGCGGAAGAGGATCCTTTCTACAGGTCCAGTTACCCCCAGCAACAGGGACTGAACACTTCGTACAGGACTGAA TCAGCCCAGCGCCAGGCATGTATGTACGCCAGCTCTGCTCCCCCCACGGACCCCGTGCCCAGCCTGGAAGACATCAGCT GTAACACGTGGCCCAGCGTGCCGTCCTACAGCAGTTGCACAGTGTCTGCCATGCAGCCCATGGACAGGTTACCCTACCA GCATTTCTCTGCCCACTTCACCTCGGGGCCTCTGATGCCCCGGCTCAGCAGCGTGGCCAACCACACGTCCCCCCAGATA GGAGACACCCATAGCATGTTCCAGCACCAGACCTCAGTTTCTCACCAACCCATTGTGCGGCAGTGTGGACCTCAGACCG GCATCCAGTCTCCCCCCAGCAGCTTGCAGCCTGCAGAGTTCCTCTATTCCCACGGCGTGCCTCGAACCCTCTCGCCCCA CCAGTACCACTCGGTGCACGGTGTGGGCATGGTGCCAGAGTGGAGCGAGAACAGCTAACGAGGCAGTCGATGGAAATGG GAAAAAAAATAAAACGAAATGAAAGAAAAAAGTGAAGGGGGAAATAAGAAAAAAGGAAAGGGAAAACAAAACAAAACAA AACAAAAAACCAGCACCCCATCAATAACAAAAACGAGAGCGTTTTGCAAGTCTCCTTTAACCGAATGTTCACCGTCAGC ACTCGAGAGGGATGGACGCTGACCGTGCCACTGGTTGGAAGCACGGATGGAGCACTCATTGGCCATGGCACGATGTGCC CCCCCCGGTGCTTTGGTTCAGAAGGCAAACCCAGCAGAGCGGAGCGCTGCCCCCACGTCCCCCCAGTCTGTGTCGCTGC CACAGCCATCCCCTGCCTGGCCCTCCCCTGCCCCTCTCCTTCCCAAAGGGACTCGCGACTCCTGCTGCCTTCCTCAACA CAGCCAGAGTGCTGGGATGAAAACAACTAGGATGTTAC
Citation	Plageman TF, Yutzey KE. T-Box genes and heart development: Putting the "T" in HearT. Dev Dyn. 2005 Jan;232(1):11-20.
Copyright	Copyright © 2005 Wiley-Liss, Inc.

Stage

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Location (click to highlight)

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31-36

stage 36

Atria
Heart
Ventricles

atrial septum (as)
interventricular septum

Entry 3

GEISHA Id	Tbx5.Lincoln.2004	Data Source	Publication
Complete cDNA Template Probe	show GAAGGCGGATGAGAACAACGGCTTTGGGTCCAAGAACACTGCCTTCTGCACCCATGTNTTCCCCGAGACTGCCTTCATT GCTGTTACCTCNTACCAAAACCACAAGATCACTCAGCTGAAGATTGAGAACAACCCCTTTGCAAAAGGTTTCCGCGGCA GCGATGACATGGAGCTCCACAGGATGTCCAGGATGCAGAGTAAAGAGTACCCAGTTGTTCCCAGGAGCACAGTGAGACA GAAAGTGTCCTCGAATCACAGCCCCTTCAGCGGTGAGACCAGGGTCCTTTCCACCTCCTCCAACCTGGGCTCCCAGTAC CAGTGTGAGAACGGGGTGTCAAGCACCTCCCAGGACCTGCTGCCACCCACCAACCCCTACCCGATCTCCCAGGAGCACA GCCAGATCTACCACTGCACCAAGAGAAAAGATGAGGAATGTTCCACCACCGAGCATCCCTACAAGAAGCCCTACATGGA AACTTCACCAGCGGAAGAGGATCCTTTCTACAGGTCCAGTTACCCCCAGCAACAGGGACTGAACACTTCGTACAGGACT GAATCAGCCCAGCGCCAGGCATGTATGTACGCCAGCTCTGCTCCCCCCACGGACCCCGTGCCCAGCCTGGAAGACATCA GCTGTAACACGTGGCCCAGCGTGCCGTCCTACAGCAGTTGCACAGTGTCTGCCATGCAGCCCATGGACAGGTTACCCTA CAGCA
Citation	Lincoln J, Alfieri CM, Yutzey KE. Development of heart valve leaflets and supporting apparatus in chicken and mouse embryos. Dev Dyn. 2004 Jun;230(2):239-50.
Copyright	Wiley-Liss, Inc. 2004

Stage

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Location (click to highlight)

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25-30

stage 29

Heart
Valves

atrial septa

31-36

stage 36

Heart
Valves

Entry 4

GEISHA Id	Tbx5.Hurtado.2006	Data Source	Publication
Complete cDNA Template Probe	show CGGGGGGCTGCCGCCATGCGGCCCCACGGTGCGGGGGTTCCTCCGGGCAGGAAGGCGGGGGCCGACCCTGCTGTCCGCA TCGCAGCGAGGAGCCGCAGCCACGCACCCCCCCGCACGCGCAGTGGGGGATTCGGCGAAGGAAGCTCGTAACATGGCGG ACACCGAGGAAGGCTTCGGGCTCCCGAGCACGCCGGTTGACTCGGAGGCCAAGGAGCTGCAGGCTGAGGCCAAGCAGGA TCCCCAGCTGGGGACCACCAGCAAGGCCCCCACCTCTCCACAGGCGGCCTTCACCCAGCAGGGCATGGAGGGGATCAAA GTGTTTTTGCACGAGCGGGAGCTGTGGCTGAAATTTCACGAGGTGGGGACGGAGATGATCATAACAAAGGCTGGAAGGC GTATGTTTCCCAGTTACAAAGTGAAGGTCACTGGACTCAATCCAAAAACGAAGTACATACTGTTGATGGATATTGTACC AGCGGATGACCACAGATACAAATTTGCAGATAATAAATGGTCCGTGACCGGGAAGGCAGAACCGGCCATGCCCGGCCGC CTCTACGTGCACCCCGACTCCCCCGCTACTGGAGCCCACTGGATGAGGCAGTTGGTTTCCTTCCAGAAGCTCAAGCTCA CCAACAACCACCTTGACCCCTTCGGACATATCATCCTGAACTCCATGCACAAATACCAGCCCCGGCTCCACATCGTGAA GGCGGATGAGAACAACGGCTTTGGCTCCAAGAACACTGCCTTCTGCACCCATGTCTTCCCCGAGACTGCCTTCATCGCT GTTACCTCCTACCAAAACCACAAGATCACTCAGCTGAAGATTGAGAACAACCCCTTCGCAAAAGGTTTCCGCGGCAGCG ATGACATGGAGCTCCACAGGATGTCCAGGATGCAGAGTAAAGAGTACCCAGTTGTTCCCAGGAGCACAGTGAGACAGAA AGTGTCCTCGAATCACAGCCCCTTCAGCGGTGAGACCAGGGTCCTTTCCACCTCCTCCAACCTGGGCTCCCAGTACCAG TGTGAGAACGGGGTGTCAAGCACCTCCCAGGACCTGCTGCCGCCCACCAACCCCTACCCGATCTCCCAGGAGCACAGCC AGATCTACCACTGCACCAAGAGAAAAGATGAGGAATGTTCCACCACCGAGCATCCCTACAAGAAGCCCTACATGGAAAC TTCACCAGCGGAAGAGGATCCTTTCTACAGGTCCAGTTACCCCCAGCAACAGGGACTGAACACTTCGTACAGGACTGAA TCAGCCCAGCGCCAGGCATGTATGTACGCCAGCTCTGCTCCCCCCACGGACCCCGTGCCCAGCCTGGAAGACATCAGCT GTAACACGTGGCCCAGCGTGCCGTCCTACAGCAGTTGCACAGTGTCTGCCATGCAGCCCATGGACAGGTTACCCTACCA GCATTTCTCTGCCCACTTCACCTCGGGGCCTCTGATGCCCCGGCTCAGCAGCGTGGCCAACCACACGTCCCCCCAGATA GGAGACACCCATAGCATGTTCCAGCACCAGACCTCAGTTTCTCACCAACCCATTGTGCGGCAGTGTGGACCTCAGACCG GCATCCAGTCTCCCCCCAGCAGCTTGCAGCCTGCAGAGTTCCTCTATTCCCACGGCGTGCCTCGAACCCTCTCGCCCCA CCAGTACCACTCGGTGCACGGTGTGGGCATGGTGCCAGAGTGGAGCGAGAACAGCTAACGAGGCAGTCGATGGAAATGG GAAAAAAAATAAAACGAAATGAAAGAAAAAAGTGAAGGGGGAAATAAGAAAAAAGGAAAGGGAAAACAAAACAAAACAA AACAAAAAACCAGCACCCCATCAATAACAAAAACGAGAGCGTTTTGCAAGTCTCCTTTAACCGAATGTTCACCGTCAGC ACTCGAGAGGGATGGACGCTGACCGTGCCACTGGTTGGAAGCACGGATGGAGCACTCATTGGCCATGGCACGATGTGCC CCCCCCGGTGCTTTGGTTCAGAAGGCAAACCCAGCAGAGCGGAGCGCTGCCCCCACGTCCCCCCAGTCTGTGTCGCTGC CACAGCCATCCCCTGCCTGGCCCTCCCCTGCCCCTCTCCTTCCCAAAGGGACTCGCGACTCCTGCTGCCTTCCTCAACA CAGCCAGAGTGCTGGGATGAAAACAACTAGGATGTTAC
Citation	Hurtado R, Mikawa T. Enhanced sensitivity and stability in two-color in situ hybridization by means of a novel chromagenic substrate combination. Dev Dyn. 2006 Oct;235(10):2811-6.
Copyright	Copyright © 2006 Wiley-Liss, Inc.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204173).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

13-18

stage 18

Atria
Ear/Otic Placcode
Eye
Heart
Hindbrain
Limb Buds
Nephric Ducts
Ventricles
Wing

Entry 5

GEISHA Id	Tbx5.Canto-Soler.2006	Data Source	Publication
Complete cDNA Template Probe	show CGGGGGGCTGCCGCCATGCGGCCCCACGGTGCGGGGGTTCCTCCGGGCAGGAAGGCGGGGGCCGACCCTGCTGTCCGCA TCGCAGCGAGGAGCCGCAGCCACGCACCCCCCCGCACGCGCAGTGGGGGATTCGGCGAAGGAAGCTCGTAACATGGCGG ACACCGAGGAAGGCTTCGGGCTCCCGAGCACGCCGGTTGACTCGGAGGCCAAGGAGCTGCAGGCTGAGGCCAAGCAGGA TCCCCAGCTGGGGACCACCAGCAAGGCCCCCACCTCTCCACAGGCGGCCTTCACCCAGCAGGGCATGGAGGGGATCAAA GTGTTTTTGCACGAGCGGGAGCTGTGGCTGAAATTTCACGAGGTGGGGACGGAGATGATCATAACAAAGGCTGGAAGGC GTATGTTTCCCAGTTACAAAGTGAAGGTCACTGGACTCAATCCAAAAACGAAGTACATACTGTTGATGGATATTGTACC AGCGGATGACCACAGATACAAATTTGCAGATAATAAATGGTCCGTGACCGGGAAGGCAGAACCGGCCATGCCCGGCCGC CTCTACGTGCACCCCGACTCCCCCGCTACTGGAGCCCACTGGATGAGGCAGTTGGTTTCCTTCCAGAAGCTCAAGCTCA CCAACAACCACCTTGACCCCTTCGGACATATCATCCTGAACTCCATGCACAAATACCAGCCCCGGCTCCACATCGTGAA GGCGGATGAGAACAACGGCTTTGGCTCCAAGAACACTGCCTTCTGCACCCATGTCTTCCCCGAGACTGCCTTCATCGCT GTTACCTCCTACCAAAACCACAAGATCACTCAGCTGAAGATTGAGAACAACCCCTTCGCAAAAGGTTTCCGCGGCAGCG ATGACATGGAGCTCCACAGGATGTCCAGGATGCAGAGTAAAGAGTACCCAGTTGTTCCCAGGAGCACAGTGAGACAGAA AGTGTCCTCGAATCACAGCCCCTTCAGCGGTGAGACCAGGGTCCTTTCCACCTCCTCCAACCTGGGCTCCCAGTACCAG TGTGAGAACGGGGTGTCAAGCACCTCCCAGGACCTGCTGCCGCCCACCAACCCCTACCCGATCTCCCAGGAGCACAGCC AGATCTACCACTGCACCAAGAGAAAAGATGAGGAATGTTCCACCACCGAGCATCCCTACAAGAAGCCCTACATGGAAAC TTCACCAGCGGAAGAGGATCCTTTCTACAGGTCCAGTTACCCCCAGCAACAGGGACTGAACACTTCGTACAGGACTGAA TCAGCCCAGCGCCAGGCATGTATGTACGCCAGCTCTGCTCCCCCCACGGACCCCGTGCCCAGCCTGGAAGACATCAGCT GTAACACGTGGCCCAGCGTGCCGTCCTACAGCAGTTGCACAGTGTCTGCCATGCAGCCCATGGACAGGTTACCCTACCA GCATTTCTCTGCCCACTTCACCTCGGGGCCTCTGATGCCCCGGCTCAGCAGCGTGGCCAACCACACGTCCCCCCAGATA GGAGACACCCATAGCATGTTCCAGCACCAGACCTCAGTTTCTCACCAACCCATTGTGCGGCAGTGTGGACCTCAGACCG GCATCCAGTCTCCCCCCAGCAGCTTGCAGCCTGCAGAGTTCCTCTATTCCCACGGCGTGCCTCGAACCCTCTCGCCCCA CCAGTACCACTCGGTGCACGGTGTGGGCATGGTGCCAGAGTGGAGCGAGAACAGCTAACGAGGCAGTCGATGGAAATGG GAAAAAAAATAAAACGAAATGAAAGAAAAAAGTGAAGGGGGAAATAAGAAAAAAGGAAAGGGAAAACAAAACAAAACAA AACAAAAAACCAGCACCCCATCAATAACAAAAACGAGAGCGTTTTGCAAGTCTCCTTTAACCGAATGTTCACCGTCAGC ACTCGAGAGGGATGGACGCTGACCGTGCCACTGGTTGGAAGCACGGATGGAGCACTCATTGGCCATGGCACGATGTGCC CCCCCCGGTGCTTTGGTTCAGAAGGCAAACCCAGCAGAGCGGAGCGCTGCCCCCACGTCCCCCCAGTCTGTGTCGCTGC CACAGCCATCCCCTGCCTGGCCCTCCCCTGCCCCTCTCCTTCCCAAAGGGACTCGCGACTCCTGCTGCCTTCCTCAACA CAGCCAGAGTGCTGGGATGAAAACAACTAGGATGTTAC
Citation	Canto-Soler MV, Adler R. Optic cup and lens development requires Pax6 expression in the early optic vesicle during a narrow time window. Dev Biol. 2006 Jun 1;294(1):119-32. Epub 2006 Mar 27.
Copyright	Reprinted from Developmental Biology, 294, Issue 1, M. Valeria Canto-Soler and Ruben Adler, Optic cup and lens development requires Pax6 expression in the early optic vesicle during a narrow time window, 119-132, 2006, with permission from Elsevier. Copyright © 2006 Elsevier B.V. All rights
Comments	The authors state: Probes were generated from cDNAs generously provided by the following investigators: cTbx5 (Katherine Yutzey, Children's Hospital Medical Center, Cincinnati, OH). As information provided was insufficient to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204173).

Stage

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Location (click to highlight)

Comments (click to highlight)

7-12

stage 11

Retina

13-18

stage 18

Retina

Entry 6

GEISHA Id	Tbx5.Krause.2004	Data Source	Publication
Reverse cDNA Template Probe	show CGGGGGGCTGCCGCCATGCGGCCCCACGGTGCGGGGGTTCCTCCGGGCAGGAAGGCGGGGGCCGACCCTGCTGTCCGCA TCGCAGCGAGGAGCCGCAGCCACGCACCCCCCCGCACGCGCAGTGGGGGATTCGGCGAAGGAAGCTCGTAACATGGCGG ACACCGAGGAAGGCTTCGGGCTCCCGAGCACGCCGGTTGACTCGGAGGCCAAGGAGCTGCAGGCTGAGGCCAAGCAGGA TCCCCAGCTGGGGACCACCAGCAAGGCCCCCACCTCTCCACAGGCGGCCTTCACCCAGCAGGGCATGGAGGGGATCAAA GTGTTTTTGCACGAGCGGGAGCTGTGGCTGAAATTTCACGAGGTGGGGACGGAGATGATCATAACAAAGGCTGGAAGGC GTATGTTTCCCAGTTACAAAGTGAAGGTCACTGGACTCAATCCAAAAACGAAGTACATACTGTTGATGGATATTGTACC AGCGGATGACCACAGATACAAATTTGCAGATAATAAATGGTCCGTGACCGGGAAGGCAGAACCGGCCATGCCCGGCCGC CTCTACGTGCACCCCGACTCCCCCGCTACTGGAGCCCACTGGATGAGGCAGTTGGTTTCCTTCCAGAAGCTCAAGCTCA CCAACAACCACCTTGACCCCTTCGGACATATCATCCTGAACTCCATGCACAAATACCAGCCCCGGCTCCACATCGTGAA GGCGGATGAGAACAACGGCTTTGGCTCCAAGAACACTGCCTTCTGCACCCATGTCTTCCCCGAGACTGCCTTCATCGCT GTTACCTCCTACCAAAACCACAAGATCACTCAGCTGAAGATTGAGAACAACCCCTTCGCAAAAGGTTTCCGCGGCAGCG ATGACATGGAGCTCCACAGGATGTCCAGGATGCAGAGTAAAGAGTACCCAGTTGTTCCCAGGAGCACAGTGAGACAGAA AGTGTCCTCGAATCACAGCCCCTTCAGCGGTGAGACCAGGGTCCTTTCCACCTCCTCCAACCTGGGCTCCCAGTACCAG TGTGAGAACGGGGTGTCAAGCACCTCCCAGGACCTGCTGCCGCCCACCAACCCCTACCCGATCTCCCAGGAGCACAGCC AGATCTACCACTGCACCAAGAGAAAAGATGAGGAATGTTCCACCACCGAGCATCCCTACAAGAAGCCCTACATGGAAAC TTCACCAGCGGAAGAGGATCCTTTCTACAGGTCCAGTTACCCCCAGCAACAGGGACTGAACACTTCGTACAGGACTGAA TCAGCCCAGCGCCAGGCATGTATGTACGCCAGCTCTGCTCCCCCCACGGACCCCGTGCCCAGCCTGGAAGACATCAGCT GTAACACGTGGCCCAGCGTGCCGTCCTACAGCAGTTGCACAGTGTCTGCCATGCAGCCCATGGACAGGTTACCCTACCA GCATTTCTCTGCCCACTTCACCTCGGGGCCTCTGATGCCCCGGCTCAGCAGCGTGGCCAACCACACGTCCCCCCAGATA GGAGACACCCATAGCATGTTCCAGCACCAGACCTCAGTTTCTCACCAACCCATTGTGCGGCAGTGTGGACCTCAGACCG GCATCCAGTCTCCCCCCAGCAGCTTGCAGCCTGCAGAGTTCCTCTATTCCCACGGCGTGCCTCGAACCCTCTCGCCCCA CCAGTACCACTCGGTGCACGGTGTGGGCATGGTGCCAGAGTGGAGCGAGAACAGCTAACGAGGCAGTCGATGGAAATGG GAAAAAAAATAAAACGAAATGAAAGAAAAAAGTGAAGGGGGAAATAAGAAAAAAGGAAAGGGAAAACAAAACAAAACAA AACAAAAAACCAGCACCCCATCAATAACAAAAACGAGAGCGTTTTGCAAGTCTCCTTTAACCGAATGTTCACCGTCAGC ACTCGAGAGGGATGGACGCTGACCGTGCCACTGGTTGGAAGCACGGATGGAGCACTCATTGGCCATGGCACGATGTGCC CCCCCCGGTGCTTTGGTTCAGAAGGCAAACCCAGCAGAGCGGAGCGCTGCCCCCACGTCCCCCCAGTCTGTGTCGCTGC CACAGCCATCCCCTGCCTGGCCCTCCCCTGCCCCTCTCCTTCCCAAAGGGACTCGCGACTCCTGCTGCCTTCCTCAACA CAGCCAGAGTGCTGGGATGAAAACAACTAGGATGTTAC
Citation	Krause A, Zacharias W, Camarata T, Linkhart B, Law E, Lischke A, Miljan E, Simon HG. Tbx5 and Tbx4 transcription factors interact with a new chicken PDZ-LIM protein in limb and heart development. Dev Biol. 2004 Sep 1;273(1):106-20.
Copyright	Reprinted from Developmental Biology, Volume 273, Issue 1, Ange Krause, William Zacharias, Troy Camarata, Barbara Linkhart, Evelyn Law, Antje Lischke, Erik Miljan, and Hans-Georg Simon, Tbx5 and Tbx4 transcription factors interact with a new chicken PDZ-LIM protein in limb and heart development, Pages 106-120, Copyright 2004, with permission from Elsevier. Copyright © 2004 Elsevier B.V. All rights reserved.
Comments	Authors said: the Tbx4 and Tbx5 antisense probes contain the 3′ untranslated regions and most of the transactivation domains. As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204173.1).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

13-18

stage 15

stage 18

Wing

19-24

stage 22

Atria
Ventricles

25-30

stage 25

stage 29

Atria
Ventricles
Wing

31-32

stage 32

Wing

Entry 7

GEISHA Id	Tbx5.Yamada.2000	Data Source	Publication
Complete cDNA Template Probe	show CGGGGGGCTGCCGCCATGCGGCCCCACGGTGCGGGGGTTCCTCCGGGCAGGAAGGCGGGGGCCGACCCTGCTGTCCGCA TCGCAGCGAGGAGCCGCAGCCACGCACCCCCCCGCACGCGCAGTGGGGGATTCGGCGAAGGAAGCTCGTAACATGGCGG ACACCGAGGAAGGCTTCGGGCTCCCGAGCACGCCGGTTGACTCGGAGGCCAAGGAGCTGCAGGCTGAGGCCAAGCAGGA TCCCCAGCTGGGGACCACCAGCAAGGCCCCCACCTCTCCACAGGCGGCCTTCACCCAGCAGGGCATGGAGGGGATCAAA GTGTTTTTGCACGAGCGGGAGCTGTGGCTGAAATTTCACGAGGTGGGGACGGAGATGATCATAACAAAGGCTGGAAGGC GTATGTTTCCCAGTTACAAAGTGAAGGTCACTGGACTCAATCCAAAAACGAAGTACATACTGTTGATGGATATTGTACC AGCGGATGACCACAGATACAAATTTGCAGATAATAAATGGTCCGTGACCGGGAAGGCAGAACCGGCCATGCCCGGCCGC CTCTACGTGCACCCCGACTCCCCCGCTACTGGAGCCCACTGGATGAGGCAGTTGGTTTCCTTCCAGAAGCTCAAGCTCA CCAACAACCACCTTGACCCCTTCGGACATATCATCCTGAACTCCATGCACAAATACCAGCCCCGGCTCCACATCGTGAA GGCGGATGAGAACAACGGCTTTGGCTCCAAGAACACTGCCTTCTGCACCCATGTCTTCCCCGAGACTGCCTTCATCGCT GTTACCTCCTACCAAAACCACAAGATCACTCAGCTGAAGATTGAGAACAACCCCTTCGCAAAAGGTTTCCGCGGCAGCG ATGACATGGAGCTCCACAGGATGTCCAGGATGCAGAGTAAAGAGTACCCAGTTGTTCCCAGGAGCACAGTGAGACAGAA AGTGTCCTCGAATCACAGCCCCTTCAGCGGTGAGACCAGGGTCCTTTCCACCTCCTCCAACCTGGGCTCCCAGTACCAG TGTGAGAACGGGGTGTCAAGCACCTCCCAGGACCTGCTGCCGCCCACCAACCCCTACCCGATCTCCCAGGAGCACAGCC AGATCTACCACTGCACCAAGAGAAAAGATGAGGAATGTTCCACCACCGAGCATCCCTACAAGAAGCCCTACATGGAAAC TTCACCAGCGGAAGAGGATCCTTTCTACAGGTCCAGTTACCCCCAGCAACAGGGACTGAACACTTCGTACAGGACTGAA TCAGCCCAGCGCCAGGCATGTATGTACGCCAGCTCTGCTCCCCCCACGGACCCCGTGCCCAGCCTGGAAGACATCAGCT GTAACACGTGGCCCAGCGTGCCGTCCTACAGCAGTTGCACAGTGTCTGCCATGCAGCCCATGGACAGGTTACCCTACCA GCATTTCTCTGCCCACTTCACCTCGGGGCCTCTGATGCCCCGGCTCAGCAGCGTGGCCAACCACACGTCCCCCCAGATA GGAGACACCCATAGCATGTTCCAGCACCAGACCTCAGTTTCTCACCAACCCATTGTGCGGCAGTGTGGACCTCAGACCG GCATCCAGTCTCCCCCCAGCAGCTTGCAGCCTGCAGAGTTCCTCTATTCCCACGGCGTGCCTCGAACCCTCTCGCCCCA CCAGTACCACTCGGTGCACGGTGTGGGCATGGTGCCAGAGTGGAGCGAGAACAGCTAACGAGGCAGTCGATGGAAATGG GAAAAAAAATAAAACGAAATGAAAGAAAAAAGTGAAGGGGGAAATAAGAAAAAAGGAAAGGGAAAACAAAACAAAACAA AACAAAAAACCAGCACCCCATCAATAACAAAAACGAGAGCGTTTTGCAAGTCTCCTTTAACCGAATGTTCACCGTCAGC ACTCGAGAGGGATGGACGCTGACCGTGCCACTGGTTGGAAGCACGGATGGAGCACTCATTGGCCATGGCACGATGTGCC CCCCCCGGTGCTTTGGTTCAGAAGGCAAACCCAGCAGAGCGGAGCGCTGCCCCCACGTCCCCCCAGTCTGTGTCGCTGC CACAGCCATCCCCTGCCTGGCCCTCCCCTGCCCCTCTCCTTCCCAAAGGGACTCGCGACTCCTGCTGCCTTCCTCAACA CAGCCAGAGTGCTGGGATGAAAACAACTAGGATGTTAC
Citation	Yamada M, Revelli JP, Eichele G, Barron M, Schwartz RJ. Expression of chick Tbx-2, Tbx-3, and Tbx-5 genes during early heart development: evidence for BMP2 induction of Tbx2. Dev Biol. 2000 Dec 1;228(1):95-105.
Copyright	Reprinted with permission from Elsevier. Copyright © 2000 Elsevier B.V. All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204173).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

4-6

stage 5

Cardiovascular
Early Embryo

Cardiogenic Region

7-12

stage 8

stage 10

Heart Tube

19-20

stage 20

Figure 1 compares expression patterns of Tbx2, Tbx3, Tbx5 and bmp2 in early chick embryos. Figure includes HH stages 5-8, 10, 11, 16, 19 and 20.

Entry 8

GEISHA Id	Tbx5.Maden.2007	Data Source	Publication
Complete cDNA Template Probe	show CGGGGGGCTGCCGCCATGCGGCCCCACGGTGCGGGGGTTCCTCCGGGCAGGAAGGCGGGGGCCGACCCTGCTGTCCGCA TCGCAGCGAGGAGCCGCAGCCACGCACCCCCCCGCACGCGCAGTGGGGGATTCGGCGAAGGAAGCTCGTAACATGGCGG ACACCGAGGAAGGCTTCGGGCTCCCGAGCACGCCGGTTGACTCGGAGGCCAAGGAGCTGCAGGCTGAGGCCAAGCAGGA TCCCCAGCTGGGGACCACCAGCAAGGCCCCCACCTCTCCACAGGCGGCCTTCACCCAGCAGGGCATGGAGGGGATCAAA GTGTTTTTGCACGAGCGGGAGCTGTGGCTGAAATTTCACGAGGTGGGGACGGAGATGATCATAACAAAGGCTGGAAGGC GTATGTTTCCCAGTTACAAAGTGAAGGTCACTGGACTCAATCCAAAAACGAAGTACATACTGTTGATGGATATTGTACC AGCGGATGACCACAGATACAAATTTGCAGATAATAAATGGTCCGTGACCGGGAAGGCAGAACCGGCCATGCCCGGCCGC CTCTACGTGCACCCCGACTCCCCCGCTACTGGAGCCCACTGGATGAGGCAGTTGGTTTCCTTCCAGAAGCTCAAGCTCA CCAACAACCACCTTGACCCCTTCGGACATATCATCCTGAACTCCATGCACAAATACCAGCCCCGGCTCCACATCGTGAA GGCGGATGAGAACAACGGCTTTGGCTCCAAGAACACTGCCTTCTGCACCCATGTCTTCCCCGAGACTGCCTTCATCGCT GTTACCTCCTACCAAAACCACAAGATCACTCAGCTGAAGATTGAGAACAACCCCTTCGCAAAAGGTTTCCGCGGCAGCG ATGACATGGAGCTCCACAGGATGTCCAGGATGCAGAGTAAAGAGTACCCAGTTGTTCCCAGGAGCACAGTGAGACAGAA AGTGTCCTCGAATCACAGCCCCTTCAGCGGTGAGACCAGGGTCCTTTCCACCTCCTCCAACCTGGGCTCCCAGTACCAG TGTGAGAACGGGGTGTCAAGCACCTCCCAGGACCTGCTGCCGCCCACCAACCCCTACCCGATCTCCCAGGAGCACAGCC AGATCTACCACTGCACCAAGAGAAAAGATGAGGAATGTTCCACCACCGAGCATCCCTACAAGAAGCCCTACATGGAAAC TTCACCAGCGGAAGAGGATCCTTTCTACAGGTCCAGTTACCCCCAGCAACAGGGACTGAACACTTCGTACAGGACTGAA TCAGCCCAGCGCCAGGCATGTATGTACGCCAGCTCTGCTCCCCCCACGGACCCCGTGCCCAGCCTGGAAGACATCAGCT GTAACACGTGGCCCAGCGTGCCGTCCTACAGCAGTTGCACAGTGTCTGCCATGCAGCCCATGGACAGGTTACCCTACCA GCATTTCTCTGCCCACTTCACCTCGGGGCCTCTGATGCCCCGGCTCAGCAGCGTGGCCAACCACACGTCCCCCCAGATA GGAGACACCCATAGCATGTTCCAGCACCAGACCTCAGTTTCTCACCAACCCATTGTGCGGCAGTGTGGACCTCAGACCG GCATCCAGTCTCCCCCCAGCAGCTTGCAGCCTGCAGAGTTCCTCTATTCCCACGGCGTGCCTCGAACCCTCTCGCCCCA CCAGTACCACTCGGTGCACGGTGTGGGCATGGTGCCAGAGTGGAGCGAGAACAGCTAACGAGGCAGTCGATGGAAATGG GAAAAAAAATAAAACGAAATGAAAGAAAAAAGTGAAGGGGGAAATAAGAAAAAAGGAAAGGGAAAACAAAACAAAACAA AACAAAAAACCAGCACCCCATCAATAACAAAAACGAGAGCGTTTTGCAAGTCTCCTTTAACCGAATGTTCACCGTCAGC ACTCGAGAGGGATGGACGCTGACCGTGCCACTGGTTGGAAGCACGGATGGAGCACTCATTGGCCATGGCACGATGTGCC CCCCCCGGTGCTTTGGTTCAGAAGGCAAACCCAGCAGAGCGGAGCGCTGCCCCCACGTCCCCCCAGTCTGTGTCGCTGC CACAGCCATCCCCTGCCTGGCCCTCCCCTGCCCCTCTCCTTCCCAAAGGGACTCGCGACTCCTGCTGCCTTCCTCAACA CAGCCAGAGTGCTGGGATGAAAACAACTAGGATGTTAC
Citation	Maden M, Blentic A, Reijntjes S, Seguin S, Gale E, Graham A. (2007). Retinoic acid is required for specification of the ventral eye field and for Rathke's pouch in the avian embryo. Int J Dev Biol. 2007;51(3):191-200.
Copyright	"Reprinted from Int. J. Dev. Biol., 51, Maden M, Blentic A, Reijntjes S, Seguin S, Gale E, Graham A, Retinoic acid is required for specification of the ventral eye field and for Rathke's pouch in the avian embryo, 191-200, Copyright (2007), with permission from Copyright © 2007 UBC Press". All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc #NM_204173). Images are quail, but sequence and map shown are chick.

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

13-18

stage 14

Eye

Quail

31-44

stage 44

Eye

Fig. 2. All images for comparison.
Quail

Entry 9

GEISHA Id	Tbx5.Liberatore.2000	Data Source	Publication
Complete cDNA Template Probe	show GAAGGCGGATGAGAACAACGGCTTTGGGTCCAAGAACACTGCCTTCTGCACCCATGTNTTCCCCGAGACTGCCTTCATT GCTGTTACCTCNTACCAAAACCACAAGATCACTCAGCTGAAGATTGAGAACAACCCCTTTGCAAAAGGTTTCCGCGGCA GCGATGACATGGAGCTCCACAGGATGTCCAGGATGCAGAGTAAAGAGTACCCAGTTGTTCCCAGGAGCACAGTGAGACA GAAAGTGTCCTCGAATCACAGCCCCTTCAGCGGTGAGACCAGGGTCCTTTCCACCTCCTCCAACCTGGGCTCCCAGTAC CAGTGTGAGAACGGGGTGTCAAGCACCTCCCAGGACCTGCTGCCACCCACCAACCCCTACCCGATCTCCCAGGAGCACA GCCAGATCTACCACTGCACCAAGAGAAAAGATGAGGAATGTTCCACCACCGAGCATCCCTACAAGAAGCCCTACATGGA AACTTCACCAGCGGAAGAGGATCCTTTCTACAGGTCCAGTTACCCCCAGCAACAGGGACTGAACACTTCGTACAGGACT GAATCAGCCCAGCGCCAGGCATGTATGTACGCCAGCTCTGCTCCCCCCACGGACCCCGTGCCCAGCCTGGAAGACATCA GCTGTAACACGTGGCCCAGCGTGCCGTCCTACAGCAGTTGCACAGTGTCTGCCATGCAGCCCATGGACAGGTTACCCTA CAG
Citation	Liberatore CM, Searcy-Schrick RD, Yutzey KE. Ventricular expression of tbx5 inhibits normal heart chamber development. Dev Biol. 2000 Jul 1;223(1):169-80.
Copyright	Reprinted with permission from Elsevier. Copyright © date Elsevier B.V. All rights reserved.
Comments	According to the authors, "Oligonucleotide primers for PCR were used to amplify nucleotides from +648 to +1361 of the reported chicken tbx5 sequence (Isaac et al., 1998) (GenBank Accession No. AF033671)." Sequence below was obtained from NCBI using this information.

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

7-12

stage 8

stage 9

stage 10

stage 12

Atria
Heart
Heart Tube
Mesoderm

A-V Junction
Cardiogenic Mesoderm
Posterior Atrial Region

13-14

stage 14

Atria
Eye
Heart
Limb Buds
Pharyngeal Arches and Clefts
Wing

A-V Junction
Figure 1 compares the expression of Tbx5, Nkx2-5 and AMHC1 in the developing heart at stages HH10, HH12 and HH14.
Posterior Atrial Region

Entry 10

GEISHA Id	TBX5.Peters.2002	Data Source	Publication
Complete cDNA Template Probe	show CGGGGGGCTGCCGCCATGCGGCCCCACGGTGCGGGGGTTCCTCCGGGCAGGAAGGCGGGGGCCGACCCTGCTGTCCGCA TCGCAGCGAGGAGCCGCAGCCACGCACCCCCCCGCACGCGCAGTGGGGGATTCGGCGAAGGAAGCTCGTAACATGGCGG ACACCGAGGAAGGCTTCGGGCTCCCGAGCACGCCGGTTGACTCGGAGGCCAAGGAGCTGCAGGCTGAGGCCAAGCAGGA TCCCCAGCTGGGGACCACCAGCAAGGCCCCCACCTCTCCACAGGCGGCCTTCACCCAGCAGGGCATGGAGGGGATCAAA GTGTTTTTGCACGAGCGGGAGCTGTGGCTGAAATTTCACGAGGTGGGGACGGAGATGATCATAACAAAGGCTGGAAGGC GTATGTTTCCCAGTTACAAAGTGAAGGTCACTGGACTCAATCCAAAAACGAAGTACATACTGTTGATGGATATTGTACC AGCGGATGACCACAGATACAAATTTGCAGATAATAAATGGTCCGTGACCGGGAAGGCAGAACCGGCCATGCCCGGCCGC CTCTACGTGCACCCCGACTCCCCCGCTACTGGAGCCCACTGGATGAGGCAGTTGGTTTCCTTCCAGAAGCTCAAGCTCA CCAACAACCACCTTGACCCCTTCGGACATATCATCCTGAACTCCATGCACAAATACCAGCCCCGGCTCCACATCGTGAA GGCGGATGAGAACAACGGCTTTGGCTCCAAGAACACTGCCTTCTGCACCCATGTCTTCCCCGAGACTGCCTTCATCGCT GTTACCTCCTACCAAAACCACAAGATCACTCAGCTGAAGATTGAGAACAACCCCTTCGCAAAAGGTTTCCGCGGCAGCG ATGACATGGAGCTCCACAGGATGTCCAGGATGCAGAGTAAAGAGTACCCAGTTGTTCCCAGGAGCACAGTGAGACAGAA AGTGTCCTCGAATCACAGCCCCTTCAGCGGTGAGACCAGGGTCCTTTCCACCTCCTCCAACCTGGGCTCCCAGTACCAG TGTGAGAACGGGGTGTCAAGCACCTCCCAGGACCTGCTGCCGCCCACCAACCCCTACCCGATCTCCCAGGAGCACAGCC AGATCTACCACTGCACCAAGAGAAAAGATGAGGAATGTTCCACCACCGAGCATCCCTACAAGAAGCCCTACATGGAAAC TTCACCAGCGGAAGAGGATCCTTTCTACAGGTCCAGTTACCCCCAGCAACAGGGACTGAACACTTCGTACAGGACTGAA TCAGCCCAGCGCCAGGCATGTATGTACGCCAGCTCTGCTCCCCCCACGGACCCCGTGCCCAGCCTGGAAGACATCAGCT GTAACACGTGGCCCAGCGTGCCGTCCTACAGCAGTTGCACAGTGTCTGCCATGCAGCCCATGGACAGGTTACCCTACCA GCATTTCTCTGCCCACTTCACCTCGGGGCCTCTGATGCCCCGGCTCAGCAGCGTGGCCAACCACACGTCCCCCCAGATA GGAGACACCCATAGCATGTTCCAGCACCAGACCTCAGTTTCTCACCAACCCATTGTGCGGCAGTGTGGACCTCAGACCG GCATCCAGTCTCCCCCCAGCAGCTTGCAGCCTGCAGAGTTCCTCTATTCCCACGGCGTGCCTCGAACCCTCTCGCCCCA CCAGTACCACTCGGTGCACGGTGTGGGCATGGTGCCAGAGTGGAGCGAGAACAGCTAACGAGGCAGTCGATGGAAATGG GAAAAAAAATAAAACGAAATGAAAGAAAAAAGTGAAGGGGGAAATAAGAAAAAAGGAAAGGGAAAACAAAACAAAACAA AACAAAAAACCAGCACCCCATCAATAACAAAAACGAGAGCGTTTTGCAAGTCTCCTTTAACCGAATGTTCACCGTCAGC ACTCGAGAGGGATGGACGCTGACCGTGCCACTGGTTGGAAGCACGGATGGAGCACTCATTGGCCATGGCACGATGTGCC CCCCCCGGTGCTTTGGTTCAGAAGGCAAACCCAGCAGAGCGGAGCGCTGCCCCCACGTCCCCCCAGTCTGTGTCGCTGC CACAGCCATCCCCTGCCTGGCCCTCCCCTGCCCCTCTCCTTCCCAAAGGGACTCGCGACTCCTGCTGCCTTCCTCAACA CAGCCAGAGTGCTGGGATGAAAACAACTAGGATGTTAC
Citation	Peters MA, Cepko CL (2002). The dorsal-ventral axis of the neural retina is divided into multiple domains of restricted gene expression which exhibit features of lineage compartments. Dev Biol. 2002 Nov 1;251(1):59-73.
Copyright	"Reprinted from Developmental Biology, 251(1), Peters MA, Cepko CL, The dorsal-ventral axis of the neural retina is divided into multiple domains of restricted gene expression which exhibit features of lineage compartments, 59-73, Copyright (2002), with permission from Elsevier". Copyright © ( 2002) Elsevier B.V. All rights reserved.
Comments	According to authors , "Probes for Pax2, Bmp4, Tbx5, SOHo, ephrin-B1, ephrin-B2, EphB1-B3, ALDH3/ALDH6, and ALDH1 were prepared as described (refs)." As information provided was insufficient to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_204173).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

13-18

stage 18

Retina

double labeled

19-24

stage 22

Retina

31-44

stage 44

Eye

Entry 11

GEISHA Id	TBX5.López-Sánchez.2010	Data Source	Publication
Complete cDNA Template Probe	show CGGGGGGCTGCCGCCATGCGGCCCCACGGTGCGGGGGTTCCTCCGGGCAGGAAGGCGGGGGCCGACCCTGCTGTCCGCA TCGCAGCGAGGAGCCGCAGCCACGCACCCCCCCGCACGCGCAGTGGGGGATTCGGCGAAGGAAGCTCGTAACATGGCGG ACACCGAGGAAGGCTTCGGGCTCCCGAGCACGCCGGTTGACTCGGAGGCCAAGGAGCTGCAGGCTGAGGCCAAGCAGGA TCCCCAGCTGGGGACCACCAGCAAGGCCCCCACCTCTCCACAGGCGGCCTTCACCCAGCAGGGCATGGAGGGGATCAAA GTGTTTTTGCACGAGCGGGAGCTGTGGCTGAAATTTCACGAGGTGGGGACGGAGATGATCATAACAAAGGCTGGAAGGC GTATGTTTCCCAGTTACAAAGTGAAGGTCACTGGACTCAATCCAAAAACGAAGTACATACTGTTGATGGATATTGTACC AGCGGATGACCACAGATACAAATTTGCAGATAATAAATGGTCCGTGACCGGGAAGGCAGAACCGGCCATGCCCGGCCGC CTCTACGTGCACCCCGACTCCCCCGCTACTGGAGCCCACTGGATGAGGCAGTTGGTTTCCTTCCAGAAGCTCAAGCTCA CCAACAACCACCTTGACCCCTTCGGACATATCATCCTGAACTCCATGCACAAATACCAGCCCCGGCTCCACATCGTGAA GGCGGATGAGAACAACGGCTTTGGCTCCAAGAACACTGCCTTCTGCACCCATGTCTTCCCCGAGACTGCCTTCATCGCT GTTACCTCCTACCAAAACCACAAGATCACTCAGCTGAAGATTGAGAACAACCCCTTCGCAAAAGGTTTCCGCGGCAGCG ATGACATGGAGCTCCACAGGATGTCCAGGATGCAGAGTAAAGAGTACCCAGTTGTTCCCAGGAGCACAGTGAGACAGAA AGTGTCCTCGAATCACAGCCCCTTCAGCGGTGAGACCAGGGTCCTTTCCACCTCCTCCAACCTGGGCTCCCAGTACCAG TGTGAGAACGGGGTGTCAAGCACCTCCCAGGACCTGCTGCCGCCCACCAACCCCTACCCGATCTCCCAGGAGCACAGCC AGATCTACCACTGCACCAAGAGAAAAGATGAGGAATGTTCCACCACCGAGCATCCCTACAAGAAGCCCTACATGGAAAC TTCACCAGCGGAAGAGGATCCTTTCTACAGGTCCAGTTACCCCCAGCAACAGGGACTGAACACTTCGTACAGGACTGAA TCAGCCCAGCGCCAGGCATGTATGTACGCCAGCTCTGCTCCCCCCACGGACCCCGTGCCCAGCCTGGAAGACATCAGCT GTAACACGTGGCCCAGCGTGCCGTCCTACAGCAGTTGCACAGTGTCTGCCATGCAGCCCATGGACAGGTTACCCTACCA GCATTTCTCTGCCCACTTCACCTCGGGGCCTCTGATGCCCCGGCTCAGCAGCGTGGCCAACCACACGTCCCCCCAGATA GGAGACACCCATAGCATGTTCCAGCACCAGACCTCAGTTTCTCACCAACCCATTGTGCGGCAGTGTGGACCTCAGACCG GCATCCAGTCTCCCCCCAGCAGCTTGCAGCCTGCAGAGTTCCTCTATTCCCACGGCGTGCCTCGAACCCTCTCGCCCCA CCAGTACCACTCGGTGCACGGTGTGGGCATGGTGCCAGAGTGGAGCGAGAACAGCTAACGAGGCAGTCGATGGAAATGG GAAAAAAAATAAAACGAAATGAAAGAAAAAAGTGAAGGGGGAAATAAGAAAAAAGGAAAGGGAAAACAAAACAAAACAA AACAAAAAACCAGCACCCCATCAATAACAAAAACGAGAGCGTTTTGCAAGTCTCCTTTAACCGAATGTTCACCGTCAGC ACTCGAGAGGGATGGACGCTGACCGTGCCACTGGTTGGAAGCACGGATGGAGCACTCATTGGCCATGGCACGATGTGCC CCCCCCGGTGCTTTGGTTCAGAAGGCAAACCCAGCAGAGCGGAGCGCTGCCCCCACGTCCCCCCAGTCTGTGTCGCTGC CACAGCCATCCCCTGCCTGGCCCTCCCCTGCCCCTCTCCTTCCCAAAGGGACTCGCGACTCCTGCTGCCTTCCTCAACA CAGCCAGAGTGCTGGGATGAAAACAACTAGGATGTTAC
Citation	López-Sánchez C, Bártulos O, Martínez-Campos E, Gañán C, Valenciano AI, García-Martínez V, De Pablo F, Hernández-Sánchez C. Tyrosine hydroxylase is expressed during early heart development and is required for cardiac chamber formation. Cardiovasc Res. 2010 Oct 1;88(1):111-20. Epub 2010 Jun 3.
Copyright	© The Author 2010.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_204173).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

7-12

stage 10

stage 11

stage 12

Heart Tube

control embryo - DMSO vehicle
control embryo - ethanol vehicle

Entry 12

GEISHA Id	TBX5.Halilagic.2007	Data Source	Publication
Complete cDNA Template Probe	show CGGGGGGCTGCCGCCATGCGGCCCCACGGTGCGGGGGTTCCTCCGGGCAGGAAGGCGGGGGCCGACCCTGCTGTCCGCA TCGCAGCGAGGAGCCGCAGCCACGCACCCCCCCGCACGCGCAGTGGGGGATTCGGCGAAGGAAGCTCGTAACATGGCGG ACACCGAGGAAGGCTTCGGGCTCCCGAGCACGCCGGTTGACTCGGAGGCCAAGGAGCTGCAGGCTGAGGCCAAGCAGGA TCCCCAGCTGGGGACCACCAGCAAGGCCCCCACCTCTCCACAGGCGGCCTTCACCCAGCAGGGCATGGAGGGGATCAAA GTGTTTTTGCACGAGCGGGAGCTGTGGCTGAAATTTCACGAGGTGGGGACGGAGATGATCATAACAAAGGCTGGAAGGC GTATGTTTCCCAGTTACAAAGTGAAGGTCACTGGACTCAATCCAAAAACGAAGTACATACTGTTGATGGATATTGTACC AGCGGATGACCACAGATACAAATTTGCAGATAATAAATGGTCCGTGACCGGGAAGGCAGAACCGGCCATGCCCGGCCGC CTCTACGTGCACCCCGACTCCCCCGCTACTGGAGCCCACTGGATGAGGCAGTTGGTTTCCTTCCAGAAGCTCAAGCTCA CCAACAACCACCTTGACCCCTTCGGACATATCATCCTGAACTCCATGCACAAATACCAGCCCCGGCTCCACATCGTGAA GGCGGATGAGAACAACGGCTTTGGCTCCAAGAACACTGCCTTCTGCACCCATGTCTTCCCCGAGACTGCCTTCATCGCT GTTACCTCCTACCAAAACCACAAGATCACTCAGCTGAAGATTGAGAACAACCCCTTCGCAAAAGGTTTCCGCGGCAGCG ATGACATGGAGCTCCACAGGATGTCCAGGATGCAGAGTAAAGAGTACCCAGTTGTTCCCAGGAGCACAGTGAGACAGAA AGTGTCCTCGAATCACAGCCCCTTCAGCGGTGAGACCAGGGTCCTTTCCACCTCCTCCAACCTGGGCTCCCAGTACCAG TGTGAGAACGGGGTGTCAAGCACCTCCCAGGACCTGCTGCCGCCCACCAACCCCTACCCGATCTCCCAGGAGCACAGCC AGATCTACCACTGCACCAAGAGAAAAGATGAGGAATGTTCCACCACCGAGCATCCCTACAAGAAGCCCTACATGGAAAC TTCACCAGCGGAAGAGGATCCTTTCTACAGGTCCAGTTACCCCCAGCAACAGGGACTGAACACTTCGTACAGGACTGAA TCAGCCCAGCGCCAGGCATGTATGTACGCCAGCTCTGCTCCCCCCACGGACCCCGTGCCCAGCCTGGAAGACATCAGCT GTAACACGTGGCCCAGCGTGCCGTCCTACAGCAGTTGCACAGTGTCTGCCATGCAGCCCATGGACAGGTTACCCTACCA GCATTTCTCTGCCCACTTCACCTCGGGGCCTCTGATGCCCCGGCTCAGCAGCGTGGCCAACCACACGTCCCCCCAGATA GGAGACACCCATAGCATGTTCCAGCACCAGACCTCAGTTTCTCACCAACCCATTGTGCGGCAGTGTGGACCTCAGACCG GCATCCAGTCTCCCCCCAGCAGCTTGCAGCCTGCAGAGTTCCTCTATTCCCACGGCGTGCCTCGAACCCTCTCGCCCCA CCAGTACCACTCGGTGCACGGTGTGGGCATGGTGCCAGAGTGGAGCGAGAACAGCTAACGAGGCAGTCGATGGAAATGG GAAAAAAAATAAAACGAAATGAAAGAAAAAAGTGAAGGGGGAAATAAGAAAAAAGGAAAGGGAAAACAAAACAAAACAA AACAAAAAACCAGCACCCCATCAATAACAAAAACGAGAGCGTTTTGCAAGTCTCCTTTAACCGAATGTTCACCGTCAGC ACTCGAGAGGGATGGACGCTGACCGTGCCACTGGTTGGAAGCACGGATGGAGCACTCATTGGCCATGGCACGATGTGCC CCCCCCGGTGCTTTGGTTCAGAAGGCAAACCCAGCAGAGCGGAGCGCTGCCCCCACGTCCCCCCAGTCTGTGTCGCTGC CACAGCCATCCCCTGCCTGGCCCTCCCCTGCCCCTCTCCTTCCCAAAGGGACTCGCGACTCCTGCTGCCTTCCTCAACA CAGCCAGAGTGCTGGGATGAAAACAACTAGGATGTTAC
Citation	Halilagic A, Ribes V, Ghyselinck NB, Zile MH, Dollé P, Studer M. Retinoids control anterior and dorsal properties in the developing forebrain. Dev Bio 2007 Mar 1;303(1):244-58
Copyright	Reprinted with permission from Elsevier. Copyright © 2007 Elsevier B.V. All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc #NM_204173). Images are quail, but sequence and map shown are chick.

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

13-18

stage 14

Eye

quail embryo

stage 19

Eye

quail embryo

Entry 13

GEISHA Id	TBX5.Hirashima.2008	Data Source	Publication
Complete cDNA Template Probe	show CGGGGGGCTGCCGCCATGCGGCCCCACGGTGCGGGGGTTCCTCCGGGCAGGAAGGCGGGGGCCGACCCTGCTGTCCGCA TCGCAGCGAGGAGCCGCAGCCACGCACCCCCCCGCACGCGCAGTGGGGGATTCGGCGAAGGAAGCTCGTAACATGGCGG ACACCGAGGAAGGCTTCGGGCTCCCGAGCACGCCGGTTGACTCGGAGGCCAAGGAGCTGCAGGCTGAGGCCAAGCAGGA TCCCCAGCTGGGGACCACCAGCAAGGCCCCCACCTCTCCACAGGCGGCCTTCACCCAGCAGGGCATGGAGGGGATCAAA GTGTTTTTGCACGAGCGGGAGCTGTGGCTGAAATTTCACGAGGTGGGGACGGAGATGATCATAACAAAGGCTGGAAGGC GTATGTTTCCCAGTTACAAAGTGAAGGTCACTGGACTCAATCCAAAAACGAAGTACATACTGTTGATGGATATTGTACC AGCGGATGACCACAGATACAAATTTGCAGATAATAAATGGTCCGTGACCGGGAAGGCAGAACCGGCCATGCCCGGCCGC CTCTACGTGCACCCCGACTCCCCCGCTACTGGAGCCCACTGGATGAGGCAGTTGGTTTCCTTCCAGAAGCTCAAGCTCA CCAACAACCACCTTGACCCCTTCGGACATATCATCCTGAACTCCATGCACAAATACCAGCCCCGGCTCCACATCGTGAA GGCGGATGAGAACAACGGCTTTGGCTCCAAGAACACTGCCTTCTGCACCCATGTCTTCCCCGAGACTGCCTTCATCGCT GTTACCTCCTACCAAAACCACAAGATCACTCAGCTGAAGATTGAGAACAACCCCTTCGCAAAAGGTTTCCGCGGCAGCG ATGACATGGAGCTCCACAGGATGTCCAGGATGCAGAGTAAAGAGTACCCAGTTGTTCCCAGGAGCACAGTGAGACAGAA AGTGTCCTCGAATCACAGCCCCTTCAGCGGTGAGACCAGGGTCCTTTCCACCTCCTCCAACCTGGGCTCCCAGTACCAG TGTGAGAACGGGGTGTCAAGCACCTCCCAGGACCTGCTGCCGCCCACCAACCCCTACCCGATCTCCCAGGAGCACAGCC AGATCTACCACTGCACCAAGAGAAAAGATGAGGAATGTTCCACCACCGAGCATCCCTACAAGAAGCCCTACATGGAAAC TTCACCAGCGGAAGAGGATCCTTTCTACAGGTCCAGTTACCCCCAGCAACAGGGACTGAACACTTCGTACAGGACTGAA TCAGCCCAGCGCCAGGCATGTATGTACGCCAGCTCTGCTCCCCCCACGGACCCCGTGCCCAGCCTGGAAGACATCAGCT GTAACACGTGGCCCAGCGTGCCGTCCTACAGCAGTTGCACAGTGTCTGCCATGCAGCCCATGGACAGGTTACCCTACCA GCATTTCTCTGCCCACTTCACCTCGGGGCCTCTGATGCCCCGGCTCAGCAGCGTGGCCAACCACACGTCCCCCCAGATA GGAGACACCCATAGCATGTTCCAGCACCAGACCTCAGTTTCTCACCAACCCATTGTGCGGCAGTGTGGACCTCAGACCG GCATCCAGTCTCCCCCCAGCAGCTTGCAGCCTGCAGAGTTCCTCTATTCCCACGGCGTGCCTCGAACCCTCTCGCCCCA CCAGTACCACTCGGTGCACGGTGTGGGCATGGTGCCAGAGTGGAGCGAGAACAGCTAACGAGGCAGTCGATGGAAATGG GAAAAAAAATAAAACGAAATGAAAGAAAAAAGTGAAGGGGGAAATAAGAAAAAAGGAAAGGGAAAACAAAACAAAACAA AACAAAAAACCAGCACCCCATCAATAACAAAAACGAGAGCGTTTTGCAAGTCTCCTTTAACCGAATGTTCACCGTCAGC ACTCGAGAGGGATGGACGCTGACCGTGCCACTGGTTGGAAGCACGGATGGAGCACTCATTGGCCATGGCACGATGTGCC CCCCCCGGTGCTTTGGTTCAGAAGGCAAACCCAGCAGAGCGGAGCGCTGCCCCCACGTCCCCCCAGTCTGTGTCGCTGC CACAGCCATCCCCTGCCTGGCCCTCCCCTGCCCCTCTCCTTCCCAAAGGGACTCGCGACTCCTGCTGCCTTCCTCAACA CAGCCAGAGTGCTGGGATGAAAACAACTAGGATGTTAC
Citation	Hirashima M, Kobayashi T, Uchikawa M, Kondoh H, Araki M. Anteroventrally localized activity in the optic vesicle plays a crucial role in the optic development. Dev Biol. 2008 May 15;317(2):620-31. doi: 10.1016/j.ydbio.2008.03.010. Epub 2008 Mar 20.
Copyright	Copyright © 2008 Elsevier Inc. All rights reserved.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_204173.1

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

7-11

stage 11

Eye

Entry 14

GEISHA Id	Tbx5.Gibson-Brown.1998	Data Source	Publication
Complete cDNA Template Probe	show CGGGGGGCTGCCGCCATGCGGCCCCACGGTGCGGGGGTTCCTCCGGGCAGGAAGGCGGGGGCCGACCCTGCTGTCCGCA TCGCAGCGAGGAGCCGCAGCCACGCACCCCCCCGCACGCGCAGTGGGGGATTCGGCGAAGGAAGCTCGTAACATGGCGG ACACCGAGGAAGGCTTCGGGCTCCCGAGCACGCCGGTTGACTCGGAGGCCAAGGAGCTGCAGGCTGAGGCCAAGCAGGA TCCCCAGCTGGGGACCACCAGCAAGGCCCCCACCTCTCCACAGGCGGCCTTCACCCAGCAGGGCATGGAGGGGATCAAA GTGTTTTTGCACGAGCGGGAGCTGTGGCTGAAATTTCACGAGGTGGGGACGGAGATGATCATAACAAAGGCTGGAAGGC GTATGTTTCCCAGTTACAAAGTGAAGGTCACTGGACTCAATCCAAAAACGAAGTACATACTGTTGATGGATATTGTACC AGCGGATGACCACAGATACAAATTTGCAGATAATAAATGGTCCGTGACCGGGAAGGCAGAACCGGCCATGCCCGGCCGC CTCTACGTGCACCCCGACTCCCCCGCTACTGGAGCCCACTGGATGAGGCAGTTGGTTTCCTTCCAGAAGCTCAAGCTCA CCAACAACCACCTTGACCCCTTCGGACATATCATCCTGAACTCCATGCACAAATACCAGCCCCGGCTCCACATCGTGAA GGCGGATGAGAACAACGGCTTTGGCTCCAAGAACACTGCCTTCTGCACCCATGTCTTCCCCGAGACTGCCTTCATCGCT GTTACCTCCTACCAAAACCACAAGATCACTCAGCTGAAGATTGAGAACAACCCCTTCGCAAAAGGTTTCCGCGGCAGCG ATGACATGGAGCTCCACAGGATGTCCAGGATGCAGAGTAAAGAGTACCCAGTTGTTCCCAGGAGCACAGTGAGACAGAA AGTGTCCTCGAATCACAGCCCCTTCAGCGGTGAGACCAGGGTCCTTTCCACCTCCTCCAACCTGGGCTCCCAGTACCAG TGTGAGAACGGGGTGTCAAGCACCTCCCAGGACCTGCTGCCGCCCACCAACCCCTACCCGATCTCCCAGGAGCACAGCC AGATCTACCACTGCACCAAGAGAAAAGATGAGGAATGTTCCACCACCGAGCATCCCTACAAGAAGCCCTACATGGAAAC TTCACCAGCGGAAGAGGATCCTTTCTACAGGTCCAGTTACCCCCAGCAACAGGGACTGAACACTTCGTACAGGACTGAA TCAGCCCAGCGCCAGGCATGTATGTACGCCAGCTCTGCTCCCCCCACGGACCCCGTGCCCAGCCTGGAAGACATCAGCT GTAACACGTGGCCCAGCGTGCCGTCCTACAGCAGTTGCACAGTGTCTGCCATGCAGCCCATGGACAGGTTACCCTACCA GCATTTCTCTGCCCACTTCACCTCGGGGCCTCTGATGCCCCGGCTCAGCAGCGTGGCCAACCACACGTCCCCCCAGATA GGAGACACCCATAGCATGTTCCAGCACCAGACCTCAGTTTCTCACCAACCCATTGTGCGGCAGTGTGGACCTCAGACCG GCATCCAGTCTCCCCCCAGCAGCTTGCAGCCTGCAGAGTTCCTCTATTCCCACGGCGTGCCTCGAACCCTCTCGCCCCA CCAGTACCACTCGGTGCACGGTGTGGGCATGGTGCCAGAGTGGAGCGAGAACAGCTAACGAGGCAGTCGATGGAAATGG GAAAAAAAATAAAACGAAATGAAAGAAAAAAGTGAAGGGGGAAATAAGAAAAAAGGAAAGGGAAAACAAAACAAAACAA AACAAAAAACCAGCACCCCATCAATAACAAAAACGAGAGCGTTTTGCAAGTCTCCTTTAACCGAATGTTCACCGTCAGC ACTCGAGAGGGATGGACGCTGACCGTGCCACTGGTTGGAAGCACGGATGGAGCACTCATTGGCCATGGCACGATGTGCC CCCCCCGGTGCTTTGGTTCAGAAGGCAAACCCAGCAGAGCGGAGCGCTGCCCCCACGTCCCCCCAGTCTGTGTCGCTGC CACAGCCATCCCCTGCCTGGCCCTCCCCTGCCCCTCTCCTTCCCAAAGGGACTCGCGACTCCTGCTGCCTTCCTCAACA CAGCCAGAGTGCTGGGATGAAAACAACTAGGATGTTAC
Citation	Gibson-Brown JJ, I Agulnik S, Silver LM, Papaioannou VE. Expression of T-box genes Tbx2-Tbx5 during chick organogenesis. Mech Dev. 1998 Jun;74(1-2):165-9.
Copyright	Copyright © 1998 Elsevier Science Ireland Ltd.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence was obtained from NCBI (NM_204173).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

13-18

stage 14

Eye
Heart

19-24

stage 20

Ear/Otic Placode
Eye
Heart
Wing

25-30

stage 25

stage 26

stage 27

Heart
Notochord

trachea

31-44

stage 44

Entry 15

GEISHA Id	TBX5.Anderson.2020	Data Source	GEISHA ISH Analysis
Complete cDNA Template Probe	show CGGAGATGATCATAACAAAGGCTGGAAGGCGTATGTTTCCCAGTTACAAAGTGAAGGTCACTGGACTCAATCCAAAAAC GAAGTACATACTGTTGATGGATATTGTACCAGCGGATGACCACAGATACAAATTTGCAGATAATAAATGGTCCGTGACC GGGAAGGCAGAACCGGCCATGCCCGGCCGCCTCTACGTGCACCCCGACTCCCCCGCTACTGGAGCCCACTGGATGAGGC AGTTGGTTTCCTTCCAGAAGCTCAAGCTCACCAACAACCACCTTGACCCCTTCGGACATATCATCCTGAACTCCATGCA CAAATACCAGCCCCGGCTCCACATCGTGAAGGCGGATGAGAACAACGGCTTTGGCTCCAAGAACACTGCCTTCTGCACC CATGTCTTCCCCGAGACTGCCTTCATCGCTGTTACCTCCTACCAAAACCACAAGATCACTCAGCTGAAGATTGAGAACA ACCCCTTCGCAAAAGGTTTCCGCGGCAGCGATGACATGGAGCTCCACAGGATGTCCAGGATGCAGAG
Comments	Images Provided by Claire Anderson; Anderson C1, Khan MAF1, Wong F2, Solovieva T1, Oliveira NMM1, Baldock RA3, Tickle C4, Burt DW2, Stern CD1. A strategy to discover new organizers identifies a putative heart organizer. Nat Commun. 2016 Aug 25;7:12656. doi: 10.1038/ncomms12656.

Stage

Image (click image to view full size)

Location (click to highlight)

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4-6

stage 4

stage 5

stage 6

Early Mesoderm
Epiblast
Lateral Plate Mesoderm
Primitive Streak

stage 4+
stage 5-, ventral

7-12

stage 8

stage 9

stage 10

stage 11

stage 12

Atria
Endocardium
Eye
Heart Tube
Lateral Plate Mesoderm
Myocardium
Sinus Venosus
Splanchnic Mesoderm
Ventricles

section 17
section 29
ventral

Entry 16

GEISHA Id	TBX5.Smith.2018	Data Source	Publication
Complete cDNA Template Probe	show CGGGGGGCTGCCGCCATGCGGCCCCACGGTGCGGGGGTTCCTCCGGGCAGGAAGGCGGGGGCCGACCCTGCTGTCCGCA TCGCAGCGAGGAGCCGCAGCCACGCACCCCCCCGCACGCGCAGTGGGGGATTCGGCGAAGGAAGCTCGTAACATGGCGG ACACCGAGGAAGGCTTCGGGCTCCCGAGCACGCCGGTTGACTCGGAGGCCAAGGAGCTGCAGGCTGAGGCCAAGCAGGA TCCCCAGCTGGGGACCACCAGCAAGGCCCCCACCTCTCCACAGGCGGCCTTCACCCAGCAGGGCATGGAGGGGATCAAA GTGTTTTTGCACGAGCGGGAGCTGTGGCTGAAATTTCACGAGGTGGGGACGGAGATGATCATAACAAAGGCTGGAAGGC GTATGTTTCCCAGTTACAAAGTGAAGGTCACTGGACTCAATCCAAAAACGAAGTACATACTGTTGATGGATATTGTACC AGCGGATGACCACAGATACAAATTTGCAGATAATAAATGGTCCGTGACCGGGAAGGCAGAACCGGCCATGCCCGGCCGC CTCTACGTGCACCCCGACTCCCCCGCTACTGGAGCCCACTGGATGAGGCAGTTGGTTTCCTTCCAGAAGCTCAAGCTCA CCAACAACCACCTTGACCCCTTCGGACATATCATCCTGAACTCCATGCACAAATACCAGCCCCGGCTCCACATCGTGAA GGCGGATGAGAACAACGGCTTTGGCTCCAAGAACACTGCCTTCTGCACCCATGTCTTCCCCGAGACTGCCTTCATCGCT GTTACCTCCTACCAAAACCACAAGATCACTCAGCTGAAGATTGAGAACAACCCCTTCGCAAAAGGTTTCCGCGGCAGCG ATGACATGGAGCTCCACAGGATGTCCAGGATGCAGAGTAAAGAGTACCCAGTTGTTCCCAGGAGCACAGTGAGACAGAA AGTGTCCTCGAATCACAGCCCCTTCAGCGGTGAGACCAGGGTCCTTTCCACCTCCTCCAACCTGGGCTCCCAGTACCAG TGTGAGAACGGGGTGTCAAGCACCTCCCAGGACCTGCTGCCGCCCACCAACCCCTACCCGATCTCCCAGGAGCACAGCC AGATCTACCACTGCACCAAGAGAAAAGATGAGGAATGTTCCACCACCGAGCATCCCTACAAGAAGCCCTACATGGAAAC TTCACCAGCGGAAGAGGATCCTTTCTACAGGTCCAGTTACCCCCAGCAACAGGGACTGAACACTTCGTACAGGACTGAA TCAGCCCAGCGCCAGGCATGTATGTACGCCAGCTCTGCTCCCCCCACGGACCCCGTGCCCAGCCTGGAAGACATCAGCT GTAACACGTGGCCCAGCGTGCCGTCCTACAGCAGTTGCACAGTGTCTGCCATGCAGCCCATGGACAGGTTACCCTACCA GCATTTCTCTGCCCACTTCACCTCGGGGCCTCTGATGCCCCGGCTCAGCAGCGTGGCCAACCACACGTCCCCCCAGATA GGAGACACCCATAGCATGTTCCAGCACCAGACCTCAGTTTCTCACCAACCCATTGTGCGGCAGTGTGGACCTCAGACCG GCATCCAGTCTCCCCCCAGCAGCTTGCAGCCTGCAGAGTTCCTCTATTCCCACGGCGTGCCTCGAACCCTCTCGCCCCA CCAGTACCACTCGGTGCACGGTGTGGGCATGGTGCCAGAGTGGAGCGAGAACAGCTAACGAGGCAGTCGATGGAAATGG GAAAAAAAATAAAACGAAATGAAAGAAAAAAGTGAAGGGGGAAATAAGAAAAAAGGAAAGGGAAAACAAAACAAAACAA AACAAAAAACCAGCACCCCATCAATAACAAAAACGAGAGCGTTTTGCAAGTCTCCTTTAACCGAATGTTCACCGTCAGC ACTCGAGAGGGATGGACGCTGACCGTGCCACTGGTTGGAAGCACGGATGGAGCACTCATTGGCCATGGCACGATGTGCC CCCCCCGGTGCTTTGGTTCAGAAGGCAAACCCAGCAGAGCGGAGCGCTGCCCCCACGTCCCCCCAGTCTGTGTCGCTGC CACAGCCATCCCCTGCCTGGCCCTCCCCTGCCCCTCTCCTTCCCAAAGGGACTCGCGACTCCTGCTGCCTTCCTCAACA CAGCCAGAGTGCTGGGATGAAAACAACTAGGATGTTAC
Citation	Jonathan N Smith, Heather M Walker, Hannah Thompson, J Martin Collinson, Neil Vargesson, Lynda Erskine. Lens-regulated retinoic acid signalling controls expansion of the developing eye. Development. 2018 Oct 10;145(19):dev167171. DOI: 10.1242/dev.167171.
Copyright	Copyright © 2018. Published by The Company of Biologists Ltd.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204173).

Stage

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Location (click to highlight)

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19-23

stage 23

Retina

all

Entry 17

GEISHA Id	TBX5.Anderson.2019	Data Source	Publication
Complete cDNA Template Probe	show CGGGGGGCTGCCGCCATGCGGCCCCACGGTGCGGGGGTTCCTCCGGGCAGGAAGGCGGGGGCCGACCCTGCTGTCCGCA TCGCAGCGAGGAGCCGCAGCCACGCACCCCCCCGCACGCGCAGTGGGGGATTCGGCGAAGGAAGCTCGTAACATGGCGG ACACCGAGGAAGGCTTCGGGCTCCCGAGCACGCCGGTTGACTCGGAGGCCAAGGAGCTGCAGGCTGAGGCCAAGCAGGA TCCCCAGCTGGGGACCACCAGCAAGGCCCCCACCTCTCCACAGGCGGCCTTCACCCAGCAGGGCATGGAGGGGATCAAA GTGTTTTTGCACGAGCGGGAGCTGTGGCTGAAATTTCACGAGGTGGGGACGGAGATGATCATAACAAAGGCTGGAAGGC GTATGTTTCCCAGTTACAAAGTGAAGGTCACTGGACTCAATCCAAAAACGAAGTACATACTGTTGATGGATATTGTACC AGCGGATGACCACAGATACAAATTTGCAGATAATAAATGGTCCGTGACCGGGAAGGCAGAACCGGCCATGCCCGGCCGC CTCTACGTGCACCCCGACTCCCCCGCTACTGGAGCCCACTGGATGAGGCAGTTGGTTTCCTTCCAGAAGCTCAAGCTCA CCAACAACCACCTTGACCCCTTCGGACATATCATCCTGAACTCCATGCACAAATACCAGCCCCGGCTCCACATCGTGAA GGCGGATGAGAACAACGGCTTTGGCTCCAAGAACACTGCCTTCTGCACCCATGTCTTCCCCGAGACTGCCTTCATCGCT GTTACCTCCTACCAAAACCACAAGATCACTCAGCTGAAGATTGAGAACAACCCCTTCGCAAAAGGTTTCCGCGGCAGCG ATGACATGGAGCTCCACAGGATGTCCAGGATGCAGAGTAAAGAGTACCCAGTTGTTCCCAGGAGCACAGTGAGACAGAA AGTGTCCTCGAATCACAGCCCCTTCAGCGGTGAGACCAGGGTCCTTTCCACCTCCTCCAACCTGGGCTCCCAGTACCAG TGTGAGAACGGGGTGTCAAGCACCTCCCAGGACCTGCTGCCGCCCACCAACCCCTACCCGATCTCCCAGGAGCACAGCC AGATCTACCACTGCACCAAGAGAAAAGATGAGGAATGTTCCACCACCGAGCATCCCTACAAGAAGCCCTACATGGAAAC TTCACCAGCGGAAGAGGATCCTTTCTACAGGTCCAGTTACCCCCAGCAACAGGGACTGAACACTTCGTACAGGACTGAA TCAGCCCAGCGCCAGGCATGTATGTACGCCAGCTCTGCTCCCCCCACGGACCCCGTGCCCAGCCTGGAAGACATCAGCT GTAACACGTGGCCCAGCGTGCCGTCCTACAGCAGTTGCACAGTGTCTGCCATGCAGCCCATGGACAGGTTACCCTACCA GCATTTCTCTGCCCACTTCACCTCGGGGCCTCTGATGCCCCGGCTCAGCAGCGTGGCCAACCACACGTCCCCCCAGATA GGAGACACCCATAGCATGTTCCAGCACCAGACCTCAGTTTCTCACCAACCCATTGTGCGGCAGTGTGGACCTCAGACCG GCATCCAGTCTCCCCCCAGCAGCTTGCAGCCTGCAGAGTTCCTCTATTCCCACGGCGTGCCTCGAACCCTCTCGCCCCA CCAGTACCACTCGGTGCACGGTGTGGGCATGGTGCCAGAGTGGAGCGAGAACAGCTAACGAGGCAGTCGATGGAAATGG GAAAAAAAATAAAACGAAATGAAAGAAAAAAGTGAAGGGGGAAATAAGAAAAAAGGAAAGGGAAAACAAAACAAAACAA AACAAAAAACCAGCACCCCATCAATAACAAAAACGAGAGCGTTTTGCAAGTCTCCTTTAACCGAATGTTCACCGTCAGC ACTCGAGAGGGATGGACGCTGACCGTGCCACTGGTTGGAAGCACGGATGGAGCACTCATTGGCCATGGCACGATGTGCC CCCCCCGGTGCTTTGGTTCAGAAGGCAAACCCAGCAGAGCGGAGCGCTGCCCCCACGTCCCCCCAGTCTGTGTCGCTGC CACAGCCATCCCCTGCCTGGCCCTCCCCTGCCCCTCTCCTTCCCAAAGGGACTCGCGACTCCTGCTGCCTTCCTCAACA CAGCCAGAGTGCTGGGATGAAAACAACTAGGATGTTAC
Citation	Anderson C, Hill B, Lu HC, Moverley A, Yang Y, Oliveira NMM, Baldock RA, Stern CD. A 3D molecular atlas of the chick embryonic heart. Dev Biol. 2019 Dec 1;456(1):40-46. doi: 10.1016/j.ydbio.2019.07.003. Epub 2019 Jul 5.
Copyright	Copyright © 2019 Elsevier Inc. All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204173).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

7-12

stage 12

Ventricles

all

Data from NCBI Unigene EST Profile
Unigene ID: Gga.961

Mouse

Emage	MGI:102541
Eurexpress	MGI:102541
MGI GXD	MGI:102541

Frog

Xenbase

486854

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFIN	ZDB-GENE-991124-7, ZDB-GENE-060601-2

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TBX5T-box 5

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Entry 4

Entry 5

Entry 6

Entry 7

Entry 8

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Entry 10

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Entry 13

Entry 14

Entry 15

Entry 16

Entry 17

Mouse

Frog

Fruit Fly

Zebra Finch

Zebrafish

TBX5
T-box 5