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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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TGFBR1
transforming growth factor beta receptor 1

The human orthologue of this gene is associated
with the following human diseases:

Gene

Official Symbol	TGFBR1
Official Full Name	transforming growth factor beta receptor 1
CGNC ID	9575
also known as	ChALK5, TGF-beta receptor type-1\|Activin like receptor kinase 5\|transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_204246
Polypeptide	NP_989577
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.143

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	35900			FBgn0011300
Human	7046	ENSG00000106799	MIM:609192	MIM:190181
Mouse	21812	ENSMUSG00000007613	All phenotypic alleles (8):Targeted, knock-out(3) Targeted, other(4) Gene trapped(1)	MGI:98728
Xenopus	548715, 399295			478586
Zebrafish	792928, 560578	ENSDARG00000042259, ENSDARG00000017494	ZDB-GENE-091027-1, ZDB-GENE-051120-75	ZFIN:ZDB-GENE-091027-1, ZFIN:ZDB-GENE-051120-75

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Links to other databases

Entrez Gene	374094
Ensembl Gene	ENSGALG00000012617
KEGG	gga:374094

Entry 1

GEISHA Id	TGFBR1.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	TATGGCGTTACGGGGCAC TC
Reverse cDNA Template Primer	AATTAACCCTCACTAAAGGTGTTCGTGATAATCTGACACCAACC	cDNA Template Length	855
Complete cDNA Template Probe	show TTTTTTAAAAGCTGCGGCCGCAGAATATTATGGCGTTACGGGGCACTGGCGGCTCCGGGCCCTGCTGCGCCTGCTGGTA GCCGCGGTCCTGCTGCCCAGGGCGGCCGCATTACAATGTTACTGCCATCTATGCACAAAGGACAACTTTACCTGTTGTG ACAGATGGGCTTTGTTTTACCTCTGTAACACGGACTGCAGATAGAGTCATACGCAATAGCATGTGTATAGCAGAAATTG ATCTGATTCCTCGAGACAGGCCATTTATTTGTGCACCATCCTTCAGAGATGGAGTTACTACTTTGCCTCATTGCTGTGA CAGAGACCACTGCAATAAAATAGAACTTCCAATTCCAACACCAGGTCCTACTCCAGGAAGACCAGCTTCTAGTCTAGGA CCTGTGGAACTGGCAGCTGTTATTGCTGGACCTGTCTGCTTTGTCTGCATTTCATTGATGCTGATTCTGTATCTTTGTC ATAACCGTACTGTAATTCATCATCGTGTGCCAAGTGAAGAAGATCCTTCATTGGATCGTCCCTTTATATCTGAAGGAAC TACTTTGAAGGATTTAATTTATGATATGACAACTTCAGGCTCTGGATCAGGTTTACCTTTACTTGTGCAAAGAACAATT GCACGAACTATAGTACTCCAAGAAAGTATTGGTAAGGGTCGCTTTGGAGAAGTATGGAGGGGGAAATGGAGAGGAGAAG AAGTTGCTGTGAAGATCTTCTCTTCAAGAGAAGAGCGCTCATGGTTTCGAGAGGCAGAAATTTATCAAACCAGTTATGC TACGACATGAAAAACATTGCTTGGATTCATAGCTGCGGACAACCAAAACAATGGTACCATGGACGCAGGTGTTGGTGTC AGATTATCACGAACACCTTTAGTGAGGGTTATTTTTAAAAC

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

1-3

stage 3

Area Pellucida
Primitive Streak

4-6

stage 5

Area Opaca
Area Pellucida

7-12

stage 9

stage 10

stage 12

Area Pellucida
Blood Vessels
Heart Tube
Lateral Plate Mesoderm
Neural Plate/Tube
Somites

13-18

stage 15

stage 17

stage 18

Ubiquitous Embryonic

19-24

stage 19

stage 25

Widespread Expression

Entry 2

GEISHA Id	ALK5.Desgrosellier.2005	Data Source	Publication
Complete cDNA Template Probe	show `CATCTATGCACAAAGGACAACTTTACCTGTGTGACAGATGGGCTTTGTTTTACCTCTGTAACACGGACTGCAGATAGAG TCATACGCAATAGCATGTGTATAGCAGAAATTGATCTGATTCCTCGAGACAGGCCATTTATTTGTGCACCATCCTTCAG AGATGGAGTTACTACTTTGCCTCATTGCTGTGACAGAGACCACTGCAATAAAATAGAACTTCCAATTCCAACACCAGGT CCTACTCCAGGAAGACCAGCTTCTAGTCTAGGACCTGTGGAACTGGCA`
Citation	Desgrosellier JS, Mundell NA, McDonnell MA, Moses HL, Barnett JV. (2005) Activin receptor-like kinase 2 and Smad6 regulate epithelial-mesenchymal transformation during cardiac valve formation. Dev Biol. 2005 Apr 1;280(1):201-10.
Copyright	Copyright © 2005 Elsevier Inc. All rights reserved.
Comments	According to the authors, "Probes were as follows: ... chicken ALK5 (GenBank Accession # D14460; nt 184468)." The sequence below was obtained from NCBI using the information provided.