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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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HBA1
hemoglobin subunit alpha 1

Gene

Official Symbol	HBA1
Official Full Name	hemoglobin subunit alpha 1
CGNC ID
also known as	HBAA, alpha-A-globin, hemoglobin subunit alpha-A\|adult alpha A globin\|alpha-A globin\|hemoglobin alpha, subunit A\|hemoglobin alpha, subunit?A\|hemoglobin alpha-A chain\|hemoglobin, alpha 1, Alpha-A- globin, Hemoglobin subunit alpha-A chain
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_001004376
Polypeptide	NP_001004376
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.34361

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	3040, 3039	ENSG00000188536, ENSG00000206172		MIM:141850, MIM:141800
Mouse	15122		All phenotypic alleles (3):Targeted, knock-out(2) Targeted, other(1)	MGI:96015
Xenopus	394454, 397869, 100216305, 379435			973888, 478140
Zebrafish	30507, 30597	ENSDARG00000097011, ENSDARG00000089475	ZDB-GENE-980526-79, ZDB-GENE-980526-80	ZFIN:ZDB-GENE-980526-79, ZFIN:ZDB-GENE-980526-80

Gene Ontology

Molecular Function	heme binding, iron ion binding, oxygen binding, oxygen transporter activity
Biological Process
Cellular Component	hemoglobin complex

Links to other databases

Entrez Gene	416652
Ensembl Gene	ENSGALG00000007468
KEGG	gga:416652

Entry 1

GEISHA Id	Hb.Jaffredo.2005	Data Source	Publication
Complete cDNA Template Probe	show AGCACGGGTGCAACCATGGTGCTGTCCGCTGCTGACAAGAACAACGTCAAGGGCATCTTCACCAAAATCGCCGGCCATG CTGAGGAGTATGGCGCCGAGACCCTGGAAAGGATGTTCACCACCTACCCCCCAACCAAGACCTACTTCCCCCACTTCGA TCTGTCACACGGCTCCGCTCAGATCAAGGGGCACGGCAAGAAGGTAGTGGCTGCCTTGATCGAGGCTGCCAACCACATT GATGACATCGCCGGCACCCTCTCCAAGCTCAGCGACCTCCATGCCCACAAGCTCCGCGTGGACCCTGTCAACTTCAAAC TCCTGGGCCAATGCTTCCTGGTGGTGGTGGCCATCCACCACCCTGCTGCCCTGACCCCGGAGGTCCATGCTTCCCTGGA CAAGTTCTTGTGCGCCGTGGGCACTGTGCTGACCGCCAAGTACCGTTAAGACGGCACGGTGGCTAGAGCTGGGGCCAAC CCATCGCCAGCCCTCCGACAGCGAGCAGCCAAATGAGATGAAATAAAATCTGTTGCATTTGTGCTCC
Citation	Jaffredo T, Bollerot K, Sugiyama D, Gautier R, Drevon C (2005). Tracing the hemangioblast during embryogenesis: developmental relationships between endothelial and hematopoietic cells. Int J Dev Biol. 2005;49(2-3):269-77.
Copyright	"Reprinted from Int. J. Dev. Biol., 49,Jaffredo T, Bollerot K, Sugiyama D, Gautier R, Drevon C , Tracing the hemangioblast during embryogenesis: developmental relationships between endothelial and hematopoietic cells, 269-77, Copyright (2005), with permission from Copyright © 2005 UBC Press". All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc #NM_001004376.) Which hemoglobin wasn't specified in the paper. This sequence is Hemoglobin A.

Stage

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Location (click to highlight)

Comments (click to highlight)

7-12

stage 9

Blood

31-44

stage 44

Blood
Blood Islands

Comparison with other genes

Entry 2

GEISHA Id	HBAA.Anderson.2021	Data Source	Direct Submission
Complete cDNA Template Probe	show GCCAACACAGAGGTGCAACCATGGTGCTGTCCGCTGCTGACAAGAACAACGTCAAGGGCATCTTCACCAAAATCGCCGG CCATGCTGAGGAGTATGGCGCCGAGACCCTGGAAAGGATGTTCACCACCTACCCCCCAACCAAGACCTACTTCCCCCAC TTCGATCTGTCACACGGCTCCGCTCAGATCAAGGGGCACGGCAAGAAGGTAGTGGCTGCCTTGATCGAGGCTGCCAACC ACATTGATGACATCGCCGGCACCCTCTCCAAGCTCAGCGACCTCCATGCCCACAAGCTCCGCGTGGACCCTGTCAACTT CAAACTCCTGGGCCAATGCTTCCTGGTGGTGGTGGCCATCCACCACCCTGCTGCCCTGACCCCGGAGGTCCATGCTTCC CTGGACAAGTTCTTGTGCGCCGTGGGCACTGTGCTGACCGCCAAGTACCGTTAAGACGGCACGGTGGCTAGAGCTGGGG CCAACCCATCGCCAGCCCTCCGACAGCGAGCAGCCAAATGAGATGAAATAAAATCTGTTGCATTTGTGCTCCA
Comments	Images and probe sequence provided by Claire Anderson. The probe was synthesized from cDNA clone ChEST973g24. Related paper: Anderson C, Hill B, Lu HC, Moverley A, Yang Y, Oliveira NMM, Baldock RA, Stern CD. A 3D molecular atlas of the chick embryonic heart. Dev Biol. 2019 Dec 1;456(1):40-46. doi: 10.1016/j.ydbio.2019.07.003. Epub 2019 Jul 5.

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

7-12

stage 12

Aorta
Blood
Blood Islands

Entry 3

GEISHA Id	HBAA.Anderson.2019	Data Source	Publication
Complete cDNA Template Probe	show CCAACACAGAGGTGCAACCATGGTGCTGTCCGCTGCTGACAAGAACAACGTCAAGGGCATCTTCACCAAAATCGCCGGC CATGCTGAGGAGTATGGCGCCGAGACCCTGGAAAGGATGTTCACCACCTACCCCCCAACCAAGACCTACTTCCCCCACT TCGATCTGTCACACGGCTCCGCTCAGATCAAGGGGCACGGCAAGAAGGTAGTGGCTGCCTTGATCGAGGCTGCCAACCA CATTGATGACATCGCCGGCACCCTCTCCAAGCTCAGCGACCTCCATGCCCACAAGCTCCGCGTGGACCCTGTCAACTTC AAACTCCTGGGCCAATGCTTCCTGGTGGTGGTGGCCATCCACCACCCTGCTGCCCTGACCCCGGAGGTCCATGCTTCCC TGGACAAGTTCTTGTGCGCCGTGGGCACTGTGCTGACCGCCAAGTACCGTTAAGACGGCACGGTGGCTAGAGCTGGGGC CAACCCATCGCCAGCCCTCCGACAGCGAGCAGCCAAATGAGATGAAATAAAATCTGT
Citation	Anderson C, Hill B, Lu HC, Moverley A, Yang Y, Oliveira NMM, Baldock RA, Stern CD. A 3D molecular atlas of the chick embryonic heart. Dev Biol. 2019 Dec 1;456(1):40-46. doi: 10.1016/j.ydbio.2019.07.003. Epub 2019 Jul 5.
Copyright	Copyright © 2019 Elsevier Inc. All rights reserved.
Comments	The complete cDNA template sequence was obtained from the information from the publication as described in Anderson et al. 2019.