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Gene Family QuickSearch
Human Disease Gene Search
SOX9 The human orthologue of this gene is associated
Gene Summary Expression Transcript Levels Other Species Expression JBrowse Gene Official Symbol SOX9 Official Full Name SRY (sex determining region Y)-box 9 CGNC ID 49063 also known as SOX-9, transcription factor SOX-9, Sox-9, Transcription factor SOX-9, SRY (sex determining region Y)-box 9 gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Gene Ontology Links to other databases
Entry 1 GEISHA Id Sox9.McKeown.2005 Data Source Publication Complete cDNA Template Probe show CTCGCATGAATCTCCTAGACCCCTTTATGAAAATGACAGAAGAACAGGATAAAGGCCTCTCCGGCGCCCCCAGCCCCAC
Citation McKeown S, Lee V, Bronner-Fraser M, Newgreen D, Farlie P. Sox10 Overexpression Induces Neural Crest-Like Cells From All Dorsoventral Levels of the Neural Tube but Inhibits Differentiation. Dev Dyn. 2005 Jun;233(2):430-44. Copyright Copyright © 2005 Wiley-Liss, Inc. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # U12533).
Entry 2 GEISHA Id Sox9.Tiecke.2006 Data Source Publication Complete cDNA Template Probe show CTCCGTCTCTGCCGGCTTTACTTCTTGTTTTTAACCCTTCCCCGCCCCTCAGCCGCCCGGTTGTTTTTTTTCTCTCCGT
Citation Tiecke E, Bangs F, Blaschke R, Farrell ER, Rappold G, Tickle C. Expression of the short stature homeobox gene Shox is restricted by proximal and distal signals in chick limb buds and affects the length of skeletal elements. Dev Biol. 2006 Oct 15;298(2):585-96. Epub 2006 Jul 12. Copyright Reprinted from Developmental Biology, 298, Eva Tiecke, Fiona Bangs, Rudiger Blaschke, Elizabeth R. Farrell, Gudrun Rappold, and Cheryll Tickie, Expression of the short stature homebox gene Shox is restricted by proximal and distal signals in chick limb buds and affects the length of skeletal elements, 585-596, 2006, with permission from Elsevier.
Copyright © 2006 Elsevier B.V. All rights reserved. Comments Authors said: "Sox9, Type II Collagen and Aggrecan (a kind gift from Prof Hurle)." As information provided was insufficient to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204281).
Entry 3 GEISHA Id Sox9.Baranski.2000 Data Source Publication Complete cDNA Template Probe show CTCCGTCTCTGCCGGCTTTACTTCTTGTTTTTAACCCTTCCCCGCCCCTCAGCCGCCCGGTTGTTTTTTTTCTCTCCGT
Citation Baranski M, Berdougo E, Sandler JS, Darnell DK, Burrus LW. The dynamic expression pattern of frzb-1 suggests multiple roles in chick development. Dev Biol. 2000 Jan 1;217(1):25-41. Copyright Copyright © 2000 Academic Press. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204281).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 31-34 stage 31
stage 34
stage 34
Leg Bones
Entry 4 GEISHA Id Sox9.Bendall.2003 Data Source Publication Complete cDNA Template Probe show CTCCGTCTCTGCCGGCTTTACTTCTTGTTTTTAACCCTTCCCCGCCCCTCAGCCGCCCGGTTGTTTTTTTTCTCTCCGT
Citation Bendall AJ, Hu G, Levi G, Abate-Shen C. Dlx5 regulates chondrocyte differentiation at multiple stages. Int J Dev Biol. 2003 Jun;47(5):335-44. Copyright "Reprinted from Int. J. Dev. Biol., 47, Bendall AJ, Hu G, Levi G, Dlx5 regulates chondrocyte differentiation at multiple stages, 335-44, Copyright (2003), with permission from Copyright © 2003 UBC Press". All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc #NM_204281).
Entry 5 GEISHA Id Sox9.Bendall.2004 Data Source GEISHA ISH Analysis Complete cDNA Template Probe show CTCCGTCTCTGCCGGCTTTACTTCTTGTTTTTAACCCTTCCCCGCCCCTCAGCCGCCCGGTTGTTTTTTTTCTCTCCGT
Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204281.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-24 stage 23
Sclerotome 25-26 stage 26
Wing Mesenchyme
Entry 6 GEISHA Id Sox9.Montero.2007 Data Source Publication Complete cDNA Template Probe show CTCCGTCTCTGCCGGCTTTACTTCTTGTTTTTAACCCTTCCCCGCCCCTCAGCCGCCCGGTTGTTTTTTTTCTCTCCGT
Citation Montero JA, Zuzarte-Luis V, Garcia-Martinez V, Hurle JM. Role of RhoC in digit morphogenesis during limb development. Dev Biol. 2007 Mar 1;303(1):325-35. Copyright Reprinted with permission from Elsevier.
Copyright © 2007 Elsevier B.V. All rights reserved. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204281).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-28 stage 28
stage 28
stage 28
stage 28
stage 28
Leg Bones
Entry 7 GEISHA Id Sox9.Theodosiou.2005 Data Source Publication Complete cDNA Template Probe show CTCCGTCTCTGCCGGCTTTACTTCTTGTTTTTAACCCTTCCCCGCCCCTCAGCCGCCCGGTTGTTTTTTTTCTCTCCGT
Citation Theodosiou NA, Tabin CJ (2005). Sox9 and Nkx2.5 determine the pyloric sphincter epithelium under the control of BMP signaling. Dev Biol. 2005 Mar 15;279(2):481-90. Copyright Copyright © 2004 Elsevier Inc. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204281).
Entry 8 GEISHA Id Sox9.Chimal-Monroy.2003 Data Source Publication Complete cDNA Template Probe show CTCCGTCTCTGCCGGCTTTACTTCTTGTTTTTAACCCTTCCCCGCCCCTCAGCCGCCCGGTTGTTTTTTTTCTCTCCGT
Citation Chimal-Monroy J, Rodriguez-Leon J, Montero JA, Gañan Y, Macias D, Merino R, Hurle JM. Analysis of the molecular cascade responsible for mesodermal limb chondrogenesis: Sox genes and BMP signaling. Dev Biol. 2003 May 15;257(2):292-301. Copyright Reprinted with permission from Elsevier.
Copyright © 2003 Elsevier B.V. All rights reserved.
Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204281.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-24 stage 22
stage 24
Leg Mesenchyme 25-30 stage 26
Leg Mesenchyme 31 stage 31
Leg Bones
Entry 9 GEISHA Id SOX9.García-Andrés.2010 Data Source Publication Complete cDNA Template Probe show CTCCGTCTCTGCCGGCTTTACTTCTTGTTTTTAACCCTTCCCCGCCCCTCAGCCGCCCGGTTGTTTTTTTTCTCTCCGT
Citation García-Andrés C, Torres M.
Comparative expression pattern analysis of the highly conserved chemokines SDF1 and CXCL14 during amniote embryonic development.
Dev Dyn. 2010 Oct;239(10):2769-77. Copyright © 2010 Wiley-Liss, Inc. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_204281).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 31 stage 31
stage 31
stage 31
stage 31
Leg Bones
Entry 10 GEISHA Id SOX9.Domowicz.2011 Data Source Publication Complete cDNA Template Probe show CTCCGTCTCTGCCGGCTTTACTTCTTGTTTTTAACCCTTCCCCGCCCCTCAGCCGCCCGGTTGTTTTTTTTCTCTCCGT
Citation Domowicz MS, Henry JG, Wadlington N, Navarro A, Kraig RP, Schwartz NB. Astrocyte precursor response to embryonic brain injury. Brain Res. 2011 May 10;1389:35-49. Epub 2011 Mar 9. Copyright Copyright © 2011, Elsevier Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204281.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 31-41 stage 37
stage 37
stage 41
stage 41
Mesencephalon
Entry 11 GEISHA Id SOX9.Thompson.2010b Data Source Publication Complete cDNA Template Probe show CTCCGTCTCTGCCGGCTTTACTTCTTGTTTTTAACCCTTCCCCGCCCCTCAGCCGCCCGGTTGTTTTTTTTCTCTCCGT
Citation H. Thompson, J.S. Griffiths, G. Jeffery, I.M. McGonnell. The retinal pigment epithelium of the eye regulates the development of scleral cartilage. Dev Biol. 2010 November 1; 347(1-13): 40-52. Copyright 2010 Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_204281.1 ).
Entry 12 GEISHA Id SOX9.Watanabe.2009 Data Source Publication Complete cDNA Template Probe show CTCCGTCTCTGCCGGCTTTACTTCTTGTTTTTAACCCTTCCCCGCCCCTCAGCCGCCCGGTTGTTTTTTTTCTCTCCGT
Citation Watanabe T, Sato Y, Saito D, Tadokoro R, Takahashi Y. EphrinB2 coordinates the formation of a morphological boundary and cell epithelialization during somite segmentation. Proc Natl Acad Sci U S A. 2009 May 5; 106(18): 74677472. Copyright Copyright 2009 national Academy of Sciences USA Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_204281.1 ).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-12 stage 12
stage 12
Neural Plate/Tube Somites
Entry 13 GEISHA Id SOX9.Szele.2002 Data Source Publication Complete cDNA Template Probe show CTCCGTCTCTGCCGGCTTTACTTCTTGTTTTTAACCCTTCCCCGCCCCTCAGCCGCCCGGTTGTTTTTTTTCTCTCCGT
Citation Szele FG, Chin HK, Rowlson MA, Cepko CL. Sox-9 and cDachsund-2 expression in the developing chick telencephalon. Mech Dev. 2002 Mar;112(1-2):179-82. Copyright Copyright © 2002 Elsevier Science Ireland Ltd. All rights reserved. Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc # NM_204281.1)
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-24 stage 24
stage 24
Telencephalon 25-30 stage 25
Telencephalon 31-37 stage 31
stage 31
stage 37
Telencephalon
Entry 14 GEISHA Id SOX9.Hu.2012 Data Source Publication Complete cDNA Template Probe show CTCCGTCTCTGCCGGCTTTACTTCTTGTTTTTAACCCTTCCCCGCCCCTCAGCCGCCCGGTTGTTTTTTTTCTCTCCGT
Citation Hu N, Strobl-Mazzulla P, Sauka-Spengler T, Bronner ME. DNA methyltransferase3A as a molecular switch mediating the neural tube-to-neural crest fate transition. Genes Dev. 2012 November 1; 26(21): 23802385. Copyright Copyright © 2012 by Cold Spring Harbor Laboratory Press Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_204281.1
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-8 stage 8
stage 8
Neural Crest Neural Plate/Tube
Entry 15 GEISHA Id SOX9.Ferronha.2013 Data Source Publication Complete cDNA Template Probe show CTCCGTCTCTGCCGGCTTTACTTCTTGTTTTTAACCCTTCCCCGCCCCTCAGCCGCCCGGTTGTTTTTTTTCTCTCCGT
Citation Ferronha T, Rabadán MA, Gil-Guiñon E, Le Dréau G, de Torres C, Martí E.
LMO4 is an essential cofactor in the Snail2-mediated epithelial-to-mesenchymal transition of neuroblastoma and neural crest cells. J Neurosci. 2013 Feb 13;33(7):2773-83.
Copyright Copyright @ 2013 by the Society of Neuroscience
Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (Acc. # NM_204269.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-10 stage 10
stage 10
Neural Crest
Entry 16 GEISHA Id SOX9.Malashichev.2005 Data Source Publication Complete cDNA Template Probe show CTCCGTCTCTGCCGGCTTTACTTCTTGTTTTTAACCCTTCCCCGCCCCTCAGCCGCCCGGTTGTTTTTTTTCTCTCCGT
Citation Malashichev Y, Borkhvardt V, Christ B, Scaal M. Differential regulation of avian pelvic girdle development by the limb field ectoderm. Anat Embryol (Berl). 2005 Oct;210(3):187-97. Epub 2005 Oct 18. Copyright © Springer, Part of Springer Science+Business Media Comments Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence was obtained from NCBI (acc #NM_204281.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-29 stage 26
stage 26
stage 27
stage 28
stage 29
Limb Buds Paraxial Mesoderm
Entry 17 GEISHA Id Sox9.Abzhanov.2004 Data Source Publication Complete cDNA Template Probe show CTCCGTCTCTGCCGGCTTTACTTCTTGTTTTTAACCCTTCCCCGCCCCTCAGCCGCCCGGTTGTTTTTTTTCTCTCCGT
Citation Abzhanov A, Tabin CJ. Shh and Fgf8 act synergistically to drive cartilage outgrowth during cranial development. Dev Biol 2004 Sep 1;273(1):134-48. Copyright Copyright © 2004 Elsevier Inc. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the complete sequence was obtained from NCBI (acc # NM_204281).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 31-36 stage 36
stage 36
Face Mesenchyme
Entry 18 Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 25-30 stage 26
stage 28
stage 28
Leg 31-44 stage 44
Data from NCBI Unigene EST ProfileGga.890
Mouse Frog Fruit Fly Zebra Finch Zebrafish
