GEISHA - A Chicken Embryo Gene Expression Database
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ADAM10
ADAM metallopeptidase domain 10

Gene
Official SymbolADAM10
Official Full NameADAM metallopeptidase domain 10
CGNC ID3093
also known asdisintegrin and metalloproteinase domain-containing protein 10|a disintegrin and metalloproteinase domain 10
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_204261
PolypeptideNP_989592
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.1343
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly43501FBgn0039688
Human102MIM:602192
Mouse11487ENSMUSG00000054693All phenotypic alleles (8):Targeted, knock-out(2) Targeted, other(6) MGI:109548
Xenopus733451, 399187945387
Zebrafish393392, 566044ENSDARG00000015502, ENSDARG00000053468ZDB-GENE-040917-2, ZDB-GENE-071115-1, ZDB-GENE-030131-2297ZFIN:ZDB-GENE-040917-2, ZFIN:ZDB-GENE-071115-1, ZFIN:ZDB-GENE-030131-2297
Gene Ontology
Molecular Function
Biological Process
Cellular Component
Links to other databases
Entrez Gene374113
Ensembl GeneENSGALG00000004212
KEGGgga:374113

Entry 1

GEISHA IdADAM10.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template PrimerGAAATGATTCGGACTGTGCGAG
Reverse cDNA Template PrimerATTAACCCTCACTAAAGGTGTCTCCAATGCTGAGGTGGTCcDNA Template Length1074
Forward cDNA Template Probeshow
TAGCCTCCTNGCCTGTCTGGCAGTTGAAAAATATATATTTTTTCAATTCTTGAATAAAAGTTTTACTACAGCCATATTT
GCCTGCAAGTGAAGAAAATGCAGCAATGAAGAGCACAGGAGGGAGAAAGAATCATGATGCTCTAGGATTTTGTGCCACT
AAATTAAAAGTATGCAAGAAAAACATTTTTCTTCTTTTTGAGCTGGAAGATTCACTCATCGTAAAATTCACCATTCCCA
CTTGTTTTGAGGGCAAGTCATGCTTTTTTTTTTCCCTCCATTTTTGNNTTAAACNGGGGNCNANGGNTTNTTAGGNTTT
TCNTTGGNNGGGGTTTTCCCCTTGGAGGN
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 5
Unlabeled
 
7-12
stage 8
stage 8
stage 8
stage 9
stage 11
stage 11
stage 11
stage 11
stage 11
Anterior Intestinal Portal
Blood Islands
Dermomyotome
Ectoderm
Extraembryonic Mesoderm
Forebrain
Foregut
Head Mesenchyme
Heart
Intermediate Mesoderm
Lateral Plate Mesoderm
Neural Plate/Tube
Notochord
Pharynx
Sinus Venosus
Somites
extraembryonic ectoderm
extraembryonic endoderm
 
13-18
stage 17
Amnion
Dermomyotome
Ear/Otic Placode
Eye
Forebrain
Foregut
Heart
Hindbrain
Leg Mesenchyme
Lung
Midbrain
Notochord
Oral Pharynx
Pharyngeal Arches and Clefts
Spinal Cord
Wing Mesenchyme
 
19-24
stage 19
stage 19
stage 19
stage 22
stage 23
Allantois
Amnion
Dermatome
Dermomyotome
Ear/Otic Placode
Endoderm
Eye
Forebrain
Foregut
Heart
Hindbrain
Hindgut
Leg Mesenchyme
Liver
Lung
Mesonephros
Midbrain
Nephric Ducts
Notochord
Pharyngeal Arches and Clefts
Sclerotome
Somatic Mesoderm
Spinal Cord
Spinal Ganglia and Nerves
Splanchnic Mesoderm
Widespread Expression
Wing Mesenchyme
 
25-27
stage 27
stage 27
stage 27
stage 27
stage 27
stage 27
stage 27
Atria
Dermomyotome
Duodenum
Endocardium
Forebrain
Foregut
Gizzard
Heart
Hindbrain
Hindgut
Leg Mesenchyme
Liver
Lung
Mesonephros
Midbrain
Myotome
Outflow Tract
Pharyngeal Arches and Clefts
Proepicardium
Sclerotome
Somatic Mesoderm
Spinal Cord
Spinal Ganglia and Nerves
Splanchnic Mesoderm
Widespread Expression
Wing Mesenchyme
 

Entry 2

GEISHA IdADAM10.Yan.2011Data SourcePublication
Complete cDNA Template Probeshow
ATGGATCTAGCGAGGACGATAATCCTGCTGTGCTCCTGGGCGGCGGGCGCCGGAGGCCAGTATGGAAATCCTCTAAATA
AATACATTAGACATTATGAAGGATTATCTTACGATGTGGATTTGTTACACCAAAAACACCAGCGTGCCAAAAGAGCAGT
ATCGCATGAAGATCAGTTCTTGCGCCTCGACTTTCATGCTCATGGAAGACAATTCAACCTTCGAATGAAGAGAGATACA
TCTCTTTTTAGTGAGGACTTTAAAGTAGAAACATCAAACCAAGTAATCGATTATGATACCTCCCATATTTACACTGGAC
ACATTTATGGTGAGCAGGGAAGTTTTAGCCATGGGTCTGTTATTGATGGAAGATTTGAAGGATTCATCCAAACTCACAG
TGGGACCTTTTATGTTGAGCCAGCAGAGAGATATATTAAGGACAGAACTCTACCGTTCCACTCTGTCATCTATCATGAA
GATGATATCAAATATCCTCATAAATATGGACCACAAGGAGGTTGTGCAGATCATTCAGTGTTTGAAAGAATGCAGAAGT
ACCAGATGACTGGTATAGAAGAACCAACAACAGAGAAGCCTTCTGAAGAGTCTGACAGCGACGGTCCTCAGCTTTTAAG
AAAAAAACGTGCCACTCAAGCTGAAAAAAACACTTGTCAGCTGTATATTCAGACTGATCATCTGTTCTATAAACACTAT
GGAACAAGGGAAGCTGTAATTGCACAGATATCCAGCCATGTTAAAGCAATTGACACAATTTACCGCTCAACAGATTTCT
CAGGAATCCGTAACATCAGCTTTATGGTGAAGCGAATAAGAATTAACACAACTGTAGATGAGAAGGACCCTTCAAATCC
CTTCAGGTTTCCTAACATTGGTGTGGAAAAGTTTCTGGAACTGAACTCAGAACAGAATCATGATGATTATTGTTTGGCC
TATGTATTTACGGACCGTGATTTTGATGATGGAGTCCTTGGTCTGGCTTGGGTTGGAGCCCCTTCAGGAAGCTCTGGTG
GGATATGTGAAAAGAGCAAACTGTATTCTGATGGTAAGAAGAAGTCTTTGAACACTGGAATCATCACTGTTCAGAACTA
TGGCTCTCATGTTCCTCCCAAGGTTTCGCATATCACTTTTGCTCATGAGGTTGGACATAACTTTGGCTCACCTCATGAT
TCTGGAATGGAATGCACTCCAGGGGAGTCCAAGAACTTGGGACAGAAAGAAAATGGGAATTACATCATGTATGCAAGAG
CTACATCTGGGGACAAACTTAATAACAACAAGTTCTCACTCTGTAGTATTCGAAATATCAGCCAAGTTCTTGAGAAAAA
GAGAAATAACTGCTTTGTTGAGTCTGGTCAACCTATCTGTGGTAATGGACTGGTAGAAGAAGGAGAGCAGTGTGATTGT
GGATACAGTGATCAGTGTAAAGATGAATGCTGTTACGATGCAAACCAATCAGATGATAAAAAATGCAAGTTAAAACCAG
GCAAATCCTGCAGCCCTAGCCAAGGCCCTTGCTGTACTGCGCAATGTAATTTCAAACTGAAGACTGATAAGTGCCGAAA
TGATTCGGACTGTGCGAGGGAGGGAATGTGTAATGGTTACAGTGCTCTCTGTCCTGCCTCTCAGCCTAAACAGAACTTC
ACAGAATGCAACAGGCGTACACAAGTTTGCATAAAAGGGCAATGTACTGGCTCTATCTGTGAGAAGTACGACTTGGAGG
AATGCACATGCGCTAGTTCGGATGGCAAGGATGACAGAGAACTGTGTCATGTCTGCTGCATGAGAAAAATGGACCCGGA
TACTTGTGCAAGCACGGGCTCCAGCCGCTGGGAGAAACACTTTGCTCGTAAAACTATTACGTTGCAACCAGGATCTCCT
TGTAATGATTTCAGAGGCTACTGTGATGTGTTTATGAGATGTCGGCTGGTAGATGCTGATGGCCCTCTAGCTCGGTTAA
AGAAAGCCATTTTTAATCCTGAGCTGTATGAAAATATTGCAGAATGGATCGTGGCTCATTGGTGGGCAGTATTGCTTAT
GGGAATTGCCCTGATCATGTTAATGGCTGGTTTCATTAAGATATGCAGTGTTCATACTCCAAGCAGTAATCCAAAGTTG
CCTCCTCATAAACCACTTCCAGGCACTTTAAAAAGGAGGAGACCGCCACAAACTGCTCAGCCACCACAGCGACAAAGGC
CCCGAGAGAGCTATCAGATGGGACATATGAGACATTGA
CitationYan X, Lin J, Rolfs A, Luo J. Differential expression of the ADAMs in developing chicken retina. Dev Growth Differ. 2011 Jun;53(5):726-39.
Copyrightcopyright 2011 The Authors
CommentsInsufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_204261).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
25-30
stage 27
stage 27
Retina
 
31-44
stage 31
stage 35
stage 38
stage 40
stage 40
stage 42
stage 44
Retina
 

Entry 3

GEISHA IdADAM10.Lin.2010BData SourcePublication
Complete cDNA Template Probeshow
ATGGATCTAGCGAGGACGATAATCCTGCTGTGCTCCTGGGCGGCGGGCGCCGGAGGCCAGTATGGAAATCCTCTAAATA
AATACATTAGACATTATGAAGGATTATCTTACGATGTGGATTTGTTACACCAAAAACACCAGCGTGCCAAAAGAGCAGT
ATCGCATGAAGATCAGTTCTTGCGCCTCGACTTTCATGCTCATGGAAGACAATTCAACCTTCGAATGAAGAGAGATACA
TCTCTTTTTAGTGAGGACTTTAAAGTAGAAACATCAAACCAAGTAATCGATTATGATACCTCCCATATTTACACTGGAC
ACATTTATGGTGAGCAGGGAAGTTTTAGCCATGGGTCTGTTATTGATGGAAGATTTGAAGGATTCATCCAAACTCACAG
TGGGACCTTTTATGTTGAGCCAGCAGAGAGATATATTAAGGACAGAACTCTACCGTTCCACTCTGTCATCTATCATGAA
GATGATATCAAATATCCTCATAAATATGGACCACAAGGAGGTTGTGCAGATCATTCAGTGTTTGAAAGAATGCAGAAGT
ACCAGATGACTGGTATAGAAGAACCAACAACAGAGAAGCCTTCTGAAGAGTCTGACAGCGACGGTCCTCAGCTTTTAAG
AAAAAAACGTGCCACTCAAGCTGAAAAAAACACTTGTCAGCTGTATATTCAGACTGATCATCTGTTCTATAAACACTAT
GGAACAAGGGAAGCTGTAATTGCACAGATATCCAGCCATGTTAAAGCAATTGACACAATTTACCGCTCAACAGATTTCT
CAGGAATCCGTAACATCAGCTTTATGGTGAAGCGAATAAGAATTAACACAACTGTAGATGAGAAGGACCCTTCAAATCC
CTTCAGGTTTCCTAACATTGGTGTGGAAAAGTTTCTGGAACTGAACTCAGAACAGAATCATGATGATTATTGTTTGGCC
TATGTATTTACGGACCGTGATTTTGATGATGGAGTCCTTGGTCTGGCTTGGGTTGGAGCCCCTTCAGGAAGCTCTGGTG
GGATATGTGAAAAGAGCAAACTGTATTCTGATGGTAAGAAGAAGTCTTTGAACACTGGAATCATCACTGTTCAGAACTA
TGGCTCTCATGTTCCTCCCAAGGTTTCGCATATCACTTTTGCTCATGAGGTTGGACATAACTTTGGCTCACCTCATGAT
TCTGGAATGGAATGCACTCCAGGGGAGTCCAAGAACTTGGGACAGAAAGAAAATGGGAATTACATCATGTATGCAAGAG
CTACATCTGGGGACAAACTTAATAACAACAAGTTCTCACTCTGTAGTATTCGAAATATCAGCCAAGTTCTTGAGAAAAA
GAGAAATAACTGCTTTGTTGAGTCTGGTCAACCTATCTGTGGTAATGGACTGGTAGAAGAAGGAGAGCAGTGTGATTGT
GGATACAGTGATCAGTGTAAAGATGAATGCTGTTACGATGCAAACCAATCAGATGATAAAAAATGCAAGTTAAAACCAG
GCAAATCCTGCAGCCCTAGCCAAGGCCCTTGCTGTACTGCGCAATGTAATTTCAAACTGAAGACTGATAAGTGCCGAAA
TGATTCGGACTGTGCGAGGGAGGGAATGTGTAATGGTTACAGTGCTCTCTGTCCTGCCTCTCAGCCTAAACAGAACTTC
ACAGAATGCAACAGGCGTACACAAGTTTGCATAAAAGGGCAATGTACTGGCTCTATCTGTGAGAAGTACGACTTGGAGG
AATGCACATGCGCTAGTTCGGATGGCAAGGATGACAGAGAACTGTGTCATGTCTGCTGCATGAGAAAAATGGACCCGGA
TACTTGTGCAAGCACGGGCTCCAGCCGCTGGGAGAAACACTTTGCTCGTAAAACTATTACGTTGCAACCAGGATCTCCT
TGTAATGATTTCAGAGGCTACTGTGATGTGTTTATGAGATGTCGGCTGGTAGATGCTGATGGCCCTCTAGCTCGGTTAA
AGAAAGCCATTTTTAATCCTGAGCTGTATGAAAATATTGCAGAATGGATCGTGGCTCATTGGTGGGCAGTATTGCTTAT
GGGAATTGCCCTGATCATGTTAATGGCTGGTTTCATTAAGATATGCAGTGTTCATACTCCAAGCAGTAATCCAAAGTTG
CCTCCTCATAAACCACTTCCAGGCACTTTAAAAAGGAGGAGACCGCCACAAACTGCTCAGCCACCACAGCGACAAAGGC
CCCGAGAGAGCTATCAGATGGGACATATGAGACATTGA
CitationLin J, Yan X, Markus A, Redies C, Rolfs A, Luo J.Dev Expression of seven members of the ADAM family in developing chicken spinal cord. Dyn. 2010 Apr;239(4):1246-54.
CommentsInsufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_204261.1).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
19-24
stage 20
stage 20
stage 20
stage 24
stage 24
Dermomyotome
Myotome
Sclerotome
Spinal Cord
Spinal Ganglia and Nerves
ep, epithelial cells of the ventricular layer
epithelial cells of the ventricular layer
floor plate
fp, floor plate
lm, lateral motor neuron column
me, meninges
25-30
stage 29
stage 29
Spinal Cord
Spinal Ganglia and Nerves
ep, epithelial cells of the ventricular layer
lm, lateral motor neuron column
me, meninges
31-37
stage 34
stage 34
stage 36
stage 37
stage 37
stage 37
stage 37
Sclerotome
Spinal Cord
Spinal Ganglia and Nerves
dh, dorsal horn
ep, epithelial cells of the ventricular layer
lm, lateral motor neuron column
me, meninges
sg, sympathetic ganglion
vr, ventral root

Entry 4

GEISHA IdADAM10.Lin.2008Data SourcePublication
Complete cDNA Template Probeshow
ATGGATCTAGCGAGGACGATAATCCTGCTGTGCTCCTGGGCGGCGGGCGCCGGAGGCCAATATGGAAATCCTCTAAATA
AATACATTAGACATTATGAAGGATTATCTTATGATGTGGATTTGTTACACCAAAAACACCAGCGTGCCAAAAGAGCAGT
ATCGCATGAAGATCAGTTCTTGCGCCTCGACTTTCATGCTCATGGAAGACAATTCAACCTTCGAATGAAGAGAGATACA
TCTCTTTTTAGTGAGGACTTTAAATTAGAAACATCAAACCAAGTAATTGATTATGATACCTCCCATATTTACACTGGAC
ACATTTATGGTGAGCAGGGAAGTTTTAGCCATGGGTCTGTTATTGATGGAAGATTTGAAGGATTCATCCAAACTCACAG
TGGGACCTTTTATGTTGAGCCAGCAGAGAGATATATTAAGGACAGAACTCTACCGTTCCACTCTGTCATCTATCATGAA
GATGATATCAAATATCCTCATAAATATGGACCACAAGGAGGTTGTGCAGATCATTCAGTGTTTGAAAGAATGCAGAAGT
ACCAGATGACTGGTATAGAAGAACCAACAACAGAGAAGCCTTCTGAAGAGTCTGACAGCGACGGTCCTCAGCTTTTAAG
AAAAAAACGTGCCACTCAAGCTGAAAAAAACACTTGTCAGCTGTATATTCAGACTGATCATCTGTTCTATAAACACTAT
GGAACAAGGGAAGCTGTAATTGCACAGATATCCAGCCATGTTAAAGCAATTGACACAATTTACCGCTCAACAGATTTCT
CAGGAATCCGTAACATCAGCTTTATGGTGAAGCGAATAAGAATTAACACAACTGTAGATGAGAAGGACCCTTCAAATCC
CTTCAGGTTTCCTAACATTGGTGTGGAAAAGTTTCTGGAACTGAACTCAGAACAGAATCATGATGATTATTGTTTGGCC
TATGTATTTACGGACCGTGATTTTGATGATGGAGTCCTTGGTCTAGCTTGGGTTGGAGCCCCTTCAGGAAGCTCTGGTG
GGATATGTGAAAAGAGCAAACTGTATTCTGATGGTAAGAAGAAGTCTTTGAACACTGGAATCATCACTGTTCAGAACTA
TGGCTCTCATGTTCCTCCCAAGGTTTCGCATATCACTTTTGCTCATGAGGTTGGACATAACTTTGGCTCACCTCATGAT
TCTGGAATGGAATGCACTCCAGGGGAGTCCAAGAACTTGGGACAGAAAGAAAATGGGAATTATATCATGTATGCAAGAG
CTACATCTGGGGACAAACTTAATAACAACAAGTTCTCACTCTGTAGTATTCGAAATATCAGCCAAGTTCTTGAGAAAAA
GAGAAATAACTGCTTTGTTGAGTCTGGTCAACCTATCTGTGGTAATGGACTGGTAGAAGAAGGAGAGCAGTGTGATTGT
GGATACAGTGATCAGTGTAAAGATGAATGCTGTTACGATGCAAACCAATCAGATGATAAAAAATGCAAGTTAAAACCAG
GCAAATCCTGCAGCCCTAGCCAAGGCCCTTGCTGTACTGCGCAATGTAATTTCAAACTGAAGACTGATAAGTGCCGAAA
TGATTCGGACTGTGCGAGGGAGGGAATGTGTAATGGTTACAGTGCTCTCTGTCCTGCCTCTCAGCCTAAACAGAACTTC
ACAGAATGCAACAGGCGTACACAAGTTTGCATAAAAGGGCAATGTACTGGCTCTATCTGTGAGAAGTACGACTTGGAGG
AATGCACATGCGCTAGTTCAGATGGCAAGGATGACAGAGAACTGTGTCATGTCTGCTGCATGAGAAAAATGGACCCGGA
TACTTGTGCAAGCACGGGCTCCAGCCGCTGGGAGAAACACTTTGCTCGTAAAACTATTACGTTGCAACCAGGATCTCCT
TGTAATGATTTCAGAGGCTACTGTGATGTGTTTATGAGATGTCGGCTGGTAGATGCTGATGGCCCTCTAGCTCGGTTAA
AGAAAGCAATTTTTAATCCTGAGCTGTATGAAAATATTGCAGAATGGATCGTGGCTCATTGGTGGGCAGTATTGCTTAT
GGGAATTGCCCTGATCATGTTAATGGCTGGTTTCATTAAGATATGCAGTGTTCATACTCCAAGCAGTAATCCAAAGTTG
CCTCCTCATAAACCACTTCCAGGCACTTTAAAAAGGAGGAGACCGCCACAAACTGCTCAGCCACCACAGCGACAAAGGC
CCCGAGAGAGCTATCAGATGGGACATATGAGACATTGA
CitationLin J, Luo J, Redies C. Differential expression of five members of the ADAM family in the developing chicken brain. Neuroscience. 2008 Nov 19;157(2):360-75. doi: 10.1016/j.neuroscience.2008.08.053. Epub 2008 Sep 4.
CopyrightCopyright © 2008 IBRO. Published by Elsevier Ltd. All rights reserved.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
25-30
stage 29
stage 29
stage 29
Hindbrain
 
31-40
stage 34
stage 34
stage 38
stage 38
stage 38
stage 38
stage 38
stage 40
stage 40
stage 40
stage 40
stage 40
Diencephalon
Hypothalamus
Mesencephalon
Telencephalon
 
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.1343

Mouse

EmageMGI:109548
EurexpressMGI:109548
MGI GXDMGI:109548

Frog

Xenbase945387

Fruit Fly

BDGPFBgn0039688

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-040917-2, ZDB-GENE-071115-1, ZDB-GENE-030131-2297
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