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PDGFB
platelet-derived growth factor beta polypeptide

Gene

Official Symbol	PDGFB
Official Full Name	platelet-derived growth factor beta polypeptide
CGNC ID	9243
also known as	platelet-derived growth factor subunit B\|platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
gene type	protein-coding

Genomic Map

Sequence Information

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.71

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	5155	ENSG00000100311	MIM:190040	MIM:190040
Mouse	18591	ENSMUSG00000000489	All phenotypic alleles (6):Targeted, knock-out(3) Targeted, other(3)	MGI:97528
Xenopus	100492827, 493575			487582
Zebrafish	796490, 798657, 565324	ENSDARG00000038139, ENSDARG00000040839	ZDB-GENE-081031-37, ZDB-GENE-050208-525	ZFIN:ZDB-GENE-081031-37, ZFIN:ZDB-GENE-050208-525

Gene Ontology

Links to other databases

GEISHA Id	PDGFB.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	TTATAAAAGCTTGCGGCCGCAGAATATAACTCAGCCCAGCCAAAACC
Reverse cDNA Template Primer	GCTCTAGAAATTAACCCTCACTAAAGGTCCCCTGCCAGCACTTCTATGC	cDNA Template Length	554
Forward cDNA Template Probe	show NGGGATTTTTNNCCCCTTTCNNCCNNAAGGTGTCCCGATCTCGAGAGAGGCGAAGCCTTGATGCTCTGGCAGCAGCATA GCCAGCTGCTCCTCGCCGAGTGCAAGACACGGACGGTGGTCTTTGAGATCTCCCGTGACATGGTGGACAGCACCAATGC CAACTTCGTGGTGTGGCCACCCTGCGTGGAGGTGCAGCGGTGCTCCGGCTGCTGCAACAACCGCAACGTGCAGTGCCGC CCCATGCAGATTCGCGTCCGGAATGTCCAGGTGAACAAGATCGAGTTTTTCCAGAGGAAGCCAATATTCAAAAAAGTCA TCGTGCCTTTGGAGGACCACGTGCAGTGCCGGTGCGAAGCGGTGTCCCGGCCGCCACCCAGGAGCATCCGACCGGCATC CCGTGAGCAGAGACGCTTCTCGCCGTCATTCACCACAGCCGCCATCTCACAGAGGAAGCGGGTACGCCGGCCGCCAGCA CAGAAGAGAAAACACTGGAAATACAAGCATGTCAACGATAAGAAAGTGCTGAAAGAAATCCTCATAGCATAGAAGTGCT GGCAGGGGACCTTTATTGAGGGTTAATTTCTANAGCAAAAA

Stage

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7-12

stage 12

stage 13

GEISHA Id	PDGFB.Yang.2008	Data Source	Publication
Complete cDNA Template Probe	show TTTATGCTCGAGGCAGCCGGCAAGGCTTGAACCCGGCATGAATTTCGGCGTGGTCTTCGCCGTCATCCTCTCCCTGCCC CTGGCCCGCCTGGAGGGGGACCCCATACCCGAAGATATTTATGAGATTTTGGGTGGCAGCTCCGTGCGCTCCATCAGTG ACCTCCAGCGTGCCCTGCGGATAGACTCCAGGAGGACAGCTCTAGCCTGGACCTGAATGCAACTCAGCCCAGCCAAAAC CATGTGTCCCTGTCTCGAGAGAGGCGAAGCCTTGATGCTCTGGCAGCAGCAGAGCCAGCTGTCCTCGCCGAGTGCAAGA CACGGACGGTGGTCTTTGAGATCTCCCGTGACATGGTGGACAGCACCAATGCCAACTTCGTGGTGTGGCCACCCTGCGT GGAGGTGCAGCGGTGCTCCGGCTGCTGCAACAACCGCAACGTGCAGTGCCGCCCCATGCAGATTCGCGTCCGGCATGTC CAGGTGAACAAGATCGAGTTTTTCCAGAGGAAGCAATATTCAAAAAAGTCATCGTGCCTTGGAGGACCACGTGCAGTGC CGGTGCGAAGCGGTGTCCCGGCCGCCACCCAGGAGCATCCGACCGGCATCCCGTGAGCAGAGACGCTTCTCGCCGTCAT TCACCACAGCCGCCATCTCCCAGAGGAAGCGGGTACGCCGGCCGCCAGCACAGAAGAGAAAACACAAGAAATACAAGCA TGTCAACGATAAGAAAGTGCTGAAAGAAATCCTCATAGCATAGAAAGTGCTGGCAGGGGAGAGAGAGCACAAGGTTTAT TTTAACTATATTTGCTGTATTGCCCCCATGGGGGTCCTTGGAGTGATAACTTTTCCTCTTTTGGCCGGTCTGGCTCAAC GACTGATTCCAGGCGGCCAATGGTGCTTCCCTTTCCATCAGTGGGACCTTCTCTAACCGAAGGCTCTCCTTCTTTCATT TTTACCTCTTAAAGTTTTCCAAAACAAAAACCCCAA
Citation	Yang X, Chrisman H, Weijer CJ. PDGF signalling controls the migration of mesoderm cells during chick gastrulation by regulating N-cadherin expression. Development. 2008 Nov;135(21):3521-30. Epub 2008 Oct 2.
Copyright	© 2008
Comments	The cDNA template used to generate the probe was obtained from EST - ChEST115n16 as described in Yang et al.