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 | IGF1
insulin like growth factor 1 | The human orthologue of this gene is associated
with the following human disease: |
| Gene | | Official Symbol | IGF1 | | Official Full Name | insulin like growth factor 1 | | CGNC ID | 9671 | | also known as | IGF-1, IGF-I, insulin-like growth factor I|insulin-like growth factor 1 (somatomedin C)|somatomedin | | gene type | protein-coding |
| | Genomic Map | | | Sequence Information | | | Gene Expression | | | Orthology | | | Gene Ontology | | Molecular Function | growth factor activity, hormone activity, insulin-like growth factor receptor binding, more...insulin receptor binding, integrin binding | | Biological Process | bone mineralization involved in bone maturation, more...extrinsic apoptotic signaling pathway in absence of ligand, muscle hypertrophy, myoblast differentiation, myoblast proliferation, myotube cell development, negative regulation of apoptotic process, negative regulation of extrinsic apoptotic signaling pathway, negative regulation of release of cytochrome c from mitochondria, negative regulation of smooth muscle cell apoptotic process, phosphatidylinositol-mediated signaling, positive regulation of activated T cell proliferation, positive regulation of calcineurin-NFAT signaling cascade, positive regulation of cardiac muscle hypertrophy, positive regulation of DNA binding, positive regulation of epithelial cell proliferation, positive regulation of fibroblast proliferation, positive regulation of glucose import, positive regulation of glycogen biosynthetic process, positive regulation of glycolysis, positive regulation of insulin-like growth factor receptor signaling pathway, positive regulation of MAPK cascade, positive regulation of mitosis, positive regulation of osteoblast differentiation, positive regulation of phosphatidylinositol 3-kinase signaling, positive regulation of protein import into nucleus, translocation, positive regulation of Ras protein signal transduction, positive regulation of smooth muscle cell migration, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tyrosine phosphorylation of Stat5 protein, proteoglycan biosynthetic process, regulation of multicellular organism growth, satellite cell maintenance involved in skeletal muscle regeneration | | Cellular Component | extracellular space |
| | Links to other databases | |
Entry 1| GEISHA Id | IGF1.Camarero.2003 | Data Source | Publication | | Complete cDNA Template Probe | show GCTGTTTCCTGTCTACAGTGTCTGTGTAATGTAGATAAATGTGAGGATTTTCTCTAAATCCCTCTTCTGTTTGCTAAAT
CTCACTGTCACTGCTAAAATCAGAGCAGATAGAGCCTGCGCAATGGAATAAAGTCCTCAATATTGAAATGTGACATTGC
TCTCAACATCTCACATCTCTCTGGATTTCTTTTTTCTCATCATTACTGCTAACAAATTCATTTCCAGACTTTGCACTTT
TAAGAAGCAATGGAAAAAATCAACAGTCTTTCAACACAATTAGTTAAGTGCTGCTTTTGTGATTTCTTGAAGGTGAAGA
TGCACACTGTGTCCTACATTCATTTCTTCTACCTTGGCCTGTGTTTGCTTACCTTAACCAGTTCTGCTGCTGCCGGCCC
AGAAACACTGTGTGGTGCTGAGCTGGTTGATGCTCTTCAGTTCGTATGTGGAGACAGAGGCTTCTACTTCAGTAAGCCT
ACAGGGTATGGATCCAGCAGTAGACGCTTACACCACAAGGGAATAGTGGATGAGTGCTGCTTCCAGAGTTGTGACCTGA
GGAGGCTGGAGATGTACTGTGCTCCAATAAAGCCACCTAAATCTGCACGCTCTGTACGTGCTCAGCGCCACACTGATAT
GCCAAAAGCACAAAAGGAAGTGCATTTGAAGAATACAAGTAGAGGGAACACAGGAAACAGAAACTACAGAATGTAAGAT
CATGCCATCCACAAGAATGAAGAATGAATGTGCCATCTGCAGAGTACTTTGCTGTAAATAAATTATTTGTTAAACATTG
GAAGACT | | Citation | Camarero G, Leon Y, Gorospe I, De Pablo F, Alsina B, Giraldez F, Varela-Nieto I. Insulin-like growth factor 1 is required for survival of transit-amplifying neuroblasts and differentiation of otic neurons. Dev Biol. 2003 Oct 15;262(2):242-53. | | Copyright | Copyright © 2003 Elsevier Inc. All rights reserved. | | Comments | Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_001004384). |
Entry 2| | Data from NCBI Unigene EST Profile
Unigene ID: Gga.850 |
MouseFrogFruit FlyZebra FinchZebrafish |
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