GEISHA - A Chicken Embryo Gene Expression Database
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GDF5
growth differentiation factor 5

The human orthologue of this gene is associated
with the following human diseases:
Gene
Official SymbolGDF5
Official Full Namegrowth differentiation factor 5
CGNC ID1254
also known asgrowth/differentiation factor 5|GDF-5 protein|growth differentiation factor 5 (cartilage-derived morphogenetic protein-1)
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_204338
PolypeptideNP_989669
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.3403
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human8200ENSG00000125965MIM:201250MIM:601146
Mouse14563ENSMUSG00000038259All phenotypic alleles (7):Spontaneous(5) Chemically induced(2) MGI:95688
Xenopus100189547, 446295481783
Zebrafish30195, 100334210ENSDARG00000002760ZDB-GENE-990415-39, ZDB-GENE-990415-39ZFIN:ZDB-GENE-990415-39, ZFIN:ZDB-GENE-990415-39
Gene Ontology
Molecular Function
Biological Process
Cellular Component
Links to other databases
Entrez Gene374249
Ensembl Gene
KEGGgga:374249

Entry 1

GEISHA IdGDF5.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template PrimerTTATAAAAGCTTGCGGCCGCAGAATATAGCAGTCACAGAGGCAAAGGTAGG
Reverse cDNA Template PrimerGCTCTAGAAATTAACCCTCACTAAAGGGTTGATTCGGGGTCCATTGAGcDNA Template Length1083
Complete cDNA Template Probeshow
AGCAGTCACAGAGGCAAAGGTAGGACATCTCCCGAGCAGACCTTCTGCAGTAAGGACGGTGACTCCAAAGGTCCCAAAT
CTTGGCAGCAAGGCGGCTCTGAAGAAAACTGGCACGGGCGGCACTGATGCCAGCTCCTTCAAAACGAAGAAGACTAAAG
AGCCTGTGACCCAAAGGGAAGCTAAGGAAACCTTCAGCAGGCCCCCTATAACGCCACATGAATACATGCTCTCTTTGTA
CAGGACTCTCTCAGATGCAGAAAGAAAAGGTGTTAATGGAAGTGTAAAACTGGAGGCTGGACTCGCCAATACAATAACC
AGCTTTATAGACAAGGGACAAGATGAGCGAGCGCCAACCATAAGAAAACAAAAATATATTTTTGACATCAGTGCATTAG
AAAAAGATGGCCTGCTGGTAGCAGAGCTTCGAATACTGAGGAAAAATCCTTCTGATACGTGGAAGTCTCATTCTTCTGG
AAAAACTTCCCAGGTGAAATTATTTAGTTGCTCTACCAACAGACAAGCAGCAACACTGCTGGACTCTCGTACCGTCAGT
ATCACGGACACACCAAAATGGGAAGTGTTTGACATCTGGAAGCTTTTTAGGAACTTTAAAAACTTGGTTAACTTGTGTT
TCGAACTGGAAACTTTTGACAGGGGGAGAGCGGTTGATCTCAGGACTGTGGGATTTAACAGAACGGGAAGACAGGTCAA
CGAAAAGGCTCTCTTCTTGGTATTTGGGAGGACAAAGAAAAGGGACTTATTTTTCAATGAAATCAAAGCTAGATCCGGC
CAGGACGACAAAACCGTGTATGAGTACTTATTCAATCAGAGGCGGAAGAGAAGAGCTCCTCTGGCAACACGCCAAGGGA
AGAGGCCCAGTAAGAACCTGAAGCCAAGGTGTAGCAGAAAAGCCCTCCATGTGAATTTTAAGGACATGGGCTGGGATGA
CTGGATAATAGCACCCCTGGAATACGAAGCGTATCACTGCGAAGGTCTGTGTGAGTTCCCCCTCCGATCCCACCTGGAG
CCCACCAATCACGCCGTTATCCAAACTTTAATGAACTCAATGGACCCCGAATCAAC
CommentsNo specific expression detected at or below stage 18.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
19-24
stage 22
stage 23
Eye
 
25
stage 25
Eye
Leg Mesenchyme
Pharyngeal Arches and Clefts
Wing Mesenchyme
 

Entry 2

GEISHA IdGDF5.Lizarraga.2002Data SourcePublication
Complete cDNA Template Probeshow
ATGAAAATCCTGCATTTTCTCACTTTACTGCTTTGGCATTTGACTTGGCTGTCTCTGGATCGTGTTCCTGGAGCACTGA
GTAACTCCGAAGCAGGCCAGAGTAATCCAGGGTCTAAAACAGATCTGTTAAAAGCAGAAGGAAAAGAGAGGACTGCCTC
AGCACGGTCGGGCGCGCCGCGGGCTGCGAACCATGGATTTAGCACCGGGACCTCGAAGGCGAGGGCTAAAAGCAACGCT
GCTCAGGCTGGAGCTCTGCTGGCCAAGAACGATGAATCACAGAGGGTTCTTTCAAGAACAGCAGTCACAGAGGCAAAGG
TAGGACATCTCCCGAGCAGACCTTCTGCAGTAAGGACGGTGACTCCAAAGGTCCCAAATCTTGGCAGCAAGGCGGCTCT
GAAGAAAACTGGCACGGGCGGCACTGATGCCAGCTCCTTCAAAACGAAGAAGACTAAAGAGCCTGTGACCCAAAGGGAA
GCTAAGGAAACCTTCAGCAGGCCCCCTATAACGCCACATGAATACATGCTCTCTTTGTACAGGACTCTCTCAGATGCAG
AAAGAAAAGGTGTTAATGGAAGTGTAAAACTGGAGGCTGGACTCGCCAATACAATAACCAGCTTTATAGACAAGGGACA
AGATGAGCGAGCGCCAACCATAAGAAAACAAAAATATATTTTTGACATCAGTGCATTAGAAAAAGATGGCCTGCTGGTA
GCAGAGCTTCGAATACTGAGGAAAAATCCTTCTGATACGTGGAAGTCTCATTCTTCTGGAAAAACTTCCCAGGTGAAAT
TATTTAGTTGCTCTACCAACAGACAAGCAGCAACACTGCTGGACTCTCGTACCGTCAGTATCACGGACACACCAAAATG
GGAAGTGTTTGACATCTGGAAGCTTTTTAGGAACTTTAAAAACTTGGTTAACTTGTGTTTCGAACTGGAAACTTTTGAC
AGGGGGAGAGCGGTTGATCTCAGGACTGTGGGATTTAACAGAACGGGAAGACAGGTCAACGAAAAGGCTCTCTTCTTGG
TATTTGGGAGGACAAAGAAAAGGGACTTATTTTTCAATGAAATCAAAGCTAGATCCGGCCAGGACGACAAAACCGTGTA
TGAGTACTTATTCAATCAGAGGCGGAAGAGAAGAGCTCCTCTGGCAACACGCCAAGGGAAGAGGCCCAGTAAGAACCTG
AAGCCAAGGTGTAGCAGAAAAGCCCTCCATGTGAATTTTAAGGACATGGGCTGGGATGACTGGATAATAGCACCCCTGG
AATACGAAGCGTATCACTGCGAAGGTCTGTGTGAGTTCCCCCTCCGATCCCACCTGGAGCCCACCAATCACGCCGTTAT
CCAAACTTTAATGAACTCAATGGACCCCGAATCAACGCCTCCAACTTGCTGTGTCCCAACCAGGCTGAGTCCTATCAGC
ATTCTCTTCATTGACTCTGCAAACAATGTGGTCTACAAGCAGTACGAGGACATGGTGGTGGAGTCGTGTGGCTGCAGGT
AGCAGAACAGTTGCTCATGTGAATGGTGTT
CitationLizarraga G, Lichtler A, Upholt WB, Kosher RA. Studies on the role of Cux1 in regulation of the onset of joint formation in the developing limb. Dev Biol. 2002 Mar 1;243(1):44-54.
CopyrightCopyright © 2002 Elsevier Science (USA). All rights reserved.
CommentsInsufficient information provided in publication to verify exact sequence to synthesize probe. Sequence below was obtained from NCBI (NM_204338).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
25-30
stage 30
stage 30
Wing Mesenchyme
Carpometacarpal Joints
Presumptive Elbow Joint
Wrist Joint
31-35
stage 35
Wing Mesenchyme
Interphalangeal Joints

Entry 3

GEISHA IdGDF-5.Pacifici.2005Data SourcePublication
Complete cDNA Template Probeshow
ATGAAAATCCTGCATTTTCTCACTTTACTGCTTTGGCATTTGACTTGGCTGTCTCTGGATCGTGTTCCTGGAGCACTGA
GTAACTCCGAAGCAGGCCAGAGTAATCCAGGGTCTAAAACAGATCTGTTAAAAGCAGAAGGAAAAGAGAGGACTGCCTC
AGCACGGTCGGGCGCGCCGCGGGCTGCGAACCATGGATTTAGCACCGGGACCTCGAAGGCGAGGGCTAAAAGCAACGCT
GCTCAGGCTGGAGCTCTGCTGGCCAAGAACGATGAATCACAGAGGGTTCTTTCAAGAACAGCAGTCACAGAGGCAAAGG
TAGGACATCTCCCGAGCAGACCTTCTGCAGTAAGGACGGTGACTCCAAAGGTCCCAAATCTTGGCAGCAAGGCGGCTCT
GAAGAAAACTGGCACGGGCGGCACTGATGCCAGCTCCTTCAAAACGAAGAAGACTAAAGAGCCTGTGACCCAAAGGGAA
GCTAAGGAAACCTTCAGCAGGCCCCCTATAACGCCACATGAATACATGCTCTCTTTGTACAGGACTCTCTCAGATGCAG
AAAGAAAAGGTGTTAATGGAAGTGTAAAACTGGAGGCTGGACTCGCCAATACAATAACCAGCTTTATAGACAAGGGACA
AGATGAGCGAGCGCCAACCATAAGAAAACAAAAATATATTTTTGACATCAGTGCATTAGAAAAAGATGGCCTGCTGGTA
GCAGAGCTTCGAATACTGAGGAAAAATCCTTCTGATACGTGGAAGTCTCATTCTTCTGGAAAAACTTCCCAGGTGAAAT
TATTTAGTTGCTCTACCAACAGACAAGCAGCAACACTGCTGGACTCTCGTACCGTCAGTATCACGGACACACCAAAATG
GGAAGTGTTTGACATCTGGAAGCTTTTTAGGAACTTTAAAAACTTGGTTAACTTGTGTTTCGAACTGGAAACTTTTGAC
AGGGGGAGAGCGGTTGATCTCAGGACTGTGGGATTTAACAGAACGGGAAGACAGGTCAACGAAAAGGCTCTCTTCTTGG
TATTTGGGAGGACAAAGAAAAGGGACTTATTTTTCAATGAAATCAAAGCTAGATCCGGCCAGGACGACAAAACCGTGTA
TGAGTACTTATTCAATCAGAGGCGGAAGAGAAGAGCTCCTCTGGCAACACGCCAAGGGAAGAGGCCCAGTAAGAACCTG
AAGCCAAGGTGTAGCAGAAAAGCCCTCCATGTGAATTTTAAGGACATGGGCTGGGATGACTGGATAATAGCACCCCTGG
AATACGAAGCGTATCACTGCGAAGGTCTGTGTGAGTTCCCCCTCCGATCCCACCTGGAGCCCACCAATCACGCCGTTAT
CCAAACTTTAATGAACTCAATGGACCCCGAATCAACGCCTCCAACTTGCTGTGTCCCAACCAGGCTGAGTCCTATCAGC
ATTCTCTTCATTGACTCTGCAAACAATGTGGTCTACAAGCAGTACGAGGACATGGTGGTGGAGTCGTGTGGCTGCAGGT
AGCAGAACAGTTGCTCATGTGAATGGTGTT
CitationPacifici M, Koyama E, Iwamoto M. Mechanisms of synovial joint and articular cartilage formation: recent advances, but many lingering mysteries. Birth Defects Res C Embryo Today. 2005 Sep;75(3):237-48.
CopyrightCopyright © 2005 Wiley-Liss, Inc.
CommentsAs insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204338.1).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
31-35
stage 35
stage 35
stage 35
stage 35
stage 35
Leg Bones
 

Entry 4

GEISHA IdGDF5.Ferrari.2006Data SourcePublication
Complete cDNA Template Probeshow
ATGAAAATCCTGCATTTTCTCACTTTACTGCTTTGGCATTTGACTTGGCTGTCTCTGGATCGTGTTCCTGGAGCACTGA
GTAACTCCGAAGCAGGCCAGAGTAATCCAGGGTCTAAAACAGATCTGTTAAAAGCAGAAGGAAAAGAGAGGACTGCCTC
AGCACGGTCGGGCGCGCCGCGGGCTGCGAACCATGGATTTAGCACCGGGACCTCGAAGGCGAGGGCTAAAAGCAACGCT
GCTCAGGCTGGAGCTCTGCTGGCCAAGAACGATGAATCACAGAGGGTTCTTTCAAGAACAGCAGTCACAGAGGCAAAGG
TAGGACATCTCCCGAGCAGACCTTCTGCAGTAAGGACGGTGACTCCAAAGGTCCCAAATCTTGGCAGCAAGGCGGCTCT
GAAGAAAACTGGCACGGGCGGCACTGATGCCAGCTCCTTCAAAACGAAGAAGACTAAAGAGCCTGTGACCCAAAGGGAA
GCTAAGGAAACCTTCAGCAGGCCCCCTATAACGCCACATGAATACATGCTCTCTTTGTACAGGACTCTCTCAGATGCAG
AAAGAAAAGGTGTTAATGGAAGTGTAAAACTGGAGGCTGGACTCGCCAATACAATAACCAGCTTTATAGACAAGGGACA
AGATGAGCGAGCGCCAACCATAAGAAAACAAAAATATATTTTTGACATCAGTGCATTAGAAAAAGATGGCCTGCTGGTA
GCAGAGCTTCGAATACTGAGGAAAAATCCTTCTGATACGTGGAAGTCTCATTCTTCTGGAAAAACTTCCCAGGTGAAAT
TATTTAGTTGCTCTACCAACAGACAAGCAGCAACACTGCTGGACTCTCGTACCGTCAGTATCACGGACACACCAAAATG
GGAAGTGTTTGACATCTGGAAGCTTTTTAGGAACTTTAAAAACTTGGTTAACTTGTGTTTCGAACTGGAAACTTTTGAC
AGGGGGAGAGCGGTTGATCTCAGGACTGTGGGATTTAACAGAACGGGAAGACAGGTCAACGAAAAGGCTCTCTTCTTGG
TATTTGGGAGGACAAAGAAAAGGGACTTATTTTTCAATGAAATCAAAGCTAGATCCGGCCAGGACGACAAAACCGTGTA
TGAGTACTTATTCAATCAGAGGCGGAAGAGAAGAGCTCCTCTGGCAACACGCCAAGGGAAGAGGCCCAGTAAGAACCTG
AAGCCAAGGTGTAGCAGAAAAGCCCTCCATGTGAATTTTAAGGACATGGGCTGGGATGACTGGATAATAGCACCCCTGG
AATACGAAGCGTATCACTGCGAAGGTCTGTGTGAGTTCCCCCTCCGATCCCACCTGGAGCCCACCAATCACGCCGTTAT
CCAAACTTTAATGAACTCAATGGACCCCGAATCAACGCCTCCAACTTGCTGTGTCCCAACCAGGCTGAGTCCTATCAGC
ATTCTCTTCATTGACTCTGCAAACAATGTGGTCTACAAGCAGTACGAGGACATGGTGGTGGAGTCGTGTGGCTGCAGGT
AGCAGAACAGTTGCTCATGTGAATGGTGTT
CitationFerrari D, Kosher RA. Expression of Dlx5 and Dlx6 during specification of the elbow joint. Int J Dev Biol. 2006;50(8):709-13.
Copyright© UBC Press
CommentsAs insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_204338.1
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
19-24
stage 23
stage 24
stage 24
Unlabeled Embryonic
Wing
 
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.3403

Mouse

EmageMGI:95688
EurexpressMGI:95688
MGI GXDMGI:95688

Frog

Xenbase481783

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-990415-39, ZDB-GENE-990415-39
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