GEISHA - A Chicken Embryo Gene Expression Database
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ALX1
ALX homeobox 1

The human orthologue of this gene is associated
with the following human disease:
Gene
Official SymbolALX1
Official Full NameALX homeobox 1
CGNC ID8462
also known asCART1, ALX homeobox protein 1|cartilage paired-class homeoprotein 1, Cartilage homeoprotein 1 (CART-1)
gene typeprotein-coding
Genomic Map
 Ensembl ID not known
NCBI
Gallus-Browse
Sequence Information
Genomic
RNAXM_425445
PolypeptideXP_425445
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST Profile
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human8092ENSG00000180318MIM:613456MIM:601527
Mouse216285ENSMUSG00000036602All phenotypic alleles (4):Targeted, knock-out(1) Targeted, other(3) MGI:104621
Xenopus100489661, 373650853094
Zebrafish565176ENSDARG00000062824ZDB-GENE-050419-191, ZDB-GENE-050419-191ZFIN:ZDB-GENE-050419-191, ZFIN:ZDB-GENE-050419-191
Gene Ontology
Molecular Function
Biological Process
Cellular Component
Links to other databases
Entrez Gene427871
Ensembl Gene
KEGGgga:427871

Entry 1

GEISHA IdALX1.53Z.A1Data SourceGEISHA ISH Analysis
Forward cDNA Template Probeshow
GGCGGCTCGAGAAGCAGCTCCCTGAGCTCCGTGTGCCTCTCCCTCCCTCCTTCCCTCCCATCCACTCCCCCTTCCCTGC
TCACAGTCCAGCCTCTGTCTAGGGGAAGAGGCTCTCCGACAGCCTTAGATGATTATGGATTTTCTGAGTGAGAAGTTTG
CCCTGAAGAGCCAGCCGAGCAAGAACAGTGACTTTTACATGGGAGCAGGAGGCACTTTGGAGCACGTTATGGAAACTTT
GGACAATGAGTCCTTTTATAGCAAAACGTCAGGCAGCAAATGTGTGCAGGCCTTCAACCCTCTGCAAAGGGCTGAGCAT
CATGTGAGGCTGGACAGGACATCACCCTGCCAAGACAACAACGGTAAGGTGACAGTCCAGCTGCATTCTGCTCCTTCTC
ACCGGGTCGGCCTCTGCTCCTGCCCGGGAGAGTGGGGGCAGCCGCGCAGCCTTTGGGTGCTGGCATGTGAGATGCAGCC
TGCTAAATAACAATTATAACAACACTATCTGTAACATCAGTAAGAATAATGATGATAACAGCGATGCAAAAAAATGGGA
AAAGGCGACTGCTGGCTTAGAAGCACCCTTCGCCTTTCTGCTGCCCTCTCCGCCGGCACCGAACAAAGTTGCTGGGCTT
TACCCCCTCCACTGGACACGCAGCTCGGTCAGGGGAACAGGCGGCGAGGAGGGAGGAAGGAGCCGGGCAGGGCTGCCGG
GGAAGGGCCGCGGCGGAGCGGCGGGGCCTGGTGGTGCGGGAGAGCTCGGCTGCGGCCCCGGCGGAGGCTACAGAGAGCC
CGGGGGCGCTGCGGCCTGTCCGCCCCGCGCCTCTCCGCTCCG
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
13-18
stage 17
stage 17
Amnion
Face Mesenchyme
pericardium
19-23
stage 19
stage 23
stage 23
Face Mesenchyme
Limb Buds
Neural Crest
Pharyngeal Arches and Clefts
Somatopleure
 

Entry 2

GEISHA IdALX1.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template PrimerTTATAAAAGCTTGCGGCCGCAGAATATGTGCAGGCCTTCAACCCTCCG
Reverse cDNA Template PrimerGCTCTAGAAATTAACCCTCACTAAAGGAAAAGCAGCAAGCTGGCTCAGAGCcDNA Template Length1387
Forward cDNA Template Probeshow
TGGTTACGGAGGCTGAGCACGCGCAGGTTGAGGACTGACGTATCAGTTCCCCTACACATATTGATCATGCCCTTCCGTC
TCTGCATGGTGTGCTTAGAGATTTACATCATGGTTCTAATACAAGAAATGAATTTTCCTTTACAGAGTTCTTCCATTAT
GAAGTATTAATTTGAAAAGTATTAATTTTGTATACAGAATTGCTAAAAACCAATGGCATAGACATATTTGCTTAATTGG
TTTATTCTTTTTTGCAAGTTCTATAATCATATTTCATCAAGTTGTACAACAGAACATGTTTCTATGTAAAAACTAAAAC
AAAGAGGGTTTGTTGAACTTGATGCATGGTAAATCTATATGGTTTATTCGTAAGTTTTATTGTTAAATATGATTTTGCA
TTTTTGTAAGCAGACATCACGTATATTGTGATTTCTAGCATTCCACACACGGCAGCTTATTGTTGTGTCCTTTAAATAT
GGAAAATAAAAATGCTTTCAGTTTACTATTTAAAAAAAAAGATATGAAGAAAGGGTACAGCTATATTACTTAGCCCAGG
AAATATTGGCAGCATGCTCTTTGGCTTTCATCCGTAGAACTGCAATGCTGGAAGATCTCCTTTCAAATTCCGGCTTGGT
TTCAAAAGCATGACCATTGGTTGCCCCGGAGCCTAAAGAGTCAGTGAAAAAATTATTGAAAGGCTCATGGCTGAACGGA
TTCTGGTGGTTTGAAAAGCCTGAGAAGCCCGAATCTTGTCCAGGGGGAATGGGAAAAGGTGTCAAACAGGAGGAAGTAT
CCCGTGGTATCCTGCGGAAGTTACCGCAGAACCCTAGCGGCGTTCCCGCCCCCACATGTTCTGATCTGAAGAAACTGGC
AACCTTGAAAAACGAATATAAAAATGCCACAAAGGCCTTAGTTGGGGGACGCCCAAAGCCCCCTTTCCCCCTTTGCCCT
CATTGGGAACAACAGGAAACGGGCTGGGGACTCGTCCTAAAAGAGCGGCCCCTCGGCCATTGGGGAAGAGTTTTGGAAA
ATTTTCCGTTCCCCCCTCCAACCGGGAAAAGGGGGGGGGTCCCTTCTCCGGGGGAAATGGGGCAACTTTCCCCATTTCA
ATCCCCTTTCGGTTCCTTTCCGAAAACAAAAATTTAAATTTAAGAGCCTGGCCTTGGAAAAAGGGCCCCCCCTTTAATC
CAAAACCATGTTTTTGGGGGGGGGGGACCCCACCAACAACCCTGCGGGGAGGGGCGTTTGCGCCTTTAAAAAAAA
CommentsNo specific expression detected at or below stage 4.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 5
stage 6
Lateral Plate Mesoderm
 
7-12
stage 7
stage 8
stage 9
stage 10
stage 10
Head Mesenchyme
Neural Crest
Dorsal view.
Ventral view.
13-18
stage 13
stage 14
stage 17
stage 18
Face Mesenchyme
Lateral Plate Mesoderm
Limb Buds
Somatic Mesoderm
 
19-24
stage 19
stage 21
stage 21
Face Mesenchyme
Limb Buds
Somatic Mesoderm
 
25-26
stage 26
stage 26
stage 26
stage 26
Face Mesenchyme
Outflow Tract
Pharyngeal Arches and Clefts
Somatic Mesoderm
 

Entry 3

GEISHA IdCART1.Thompson.2010bData SourcePublication
Complete cDNA Template Probeshow
GTCTAGGGGAAGAGGCTCTCCGACAGCCTTAGATGATTATGGATTTTCTGAGTGAGAAGTTTGCCCTGAAGAGCCAGCC
GAGCAAGAACAGTGACTTTTACATGGGAGCAGGAGGCACTTTGGAGCACGTTATGGAAACTTTGGACAATGAGTCCTTT
TATAGCAAAACGTCAGGCAGCAAATGTGTGCAGGCCTTCAACCCTCTGCAAAGGGCTGAGCATCATGTGAGGCTGGACA
GGACATCACCCTGCCAAGACAACAACGTGAACTATGGGATTACTAAAGTGGAAGGACAGCCTCTTCACACAGAGCTCAA
CAGGCCCTTGGACAACTGCAACAATCTGAGGATGTCTCCGGTGAAGGGGATGCAGGAGAAGGGGGAACTGGATGAACTG
GGTGATAAGTGTGACAGCAATGTCTCCAGCAGTAAGAAGAGGAGACACAGAACAACTTTCACCAGTTTGCAGCTGGAGG
AACTGGAGAAAGTCTTCCAGAAAACTCATTACCCTGATGTCTACGTGAGGGAGCAGCTAGCTCTGAGGACAGAGCTCAC
CGAGGCCAGAGTCCAGGTTTGGTTCCAGAATAGAAGAGCAAAATGGAGGAAAAGAGAACGCTATGGGCAGATCCAGCAA
GCTAAGAGCCATTTTGCTGCCACTTATGATATATCTGTTCTTCCAAGGACTGACAGCTATCCTCAGATTCAGAACAATC
TGTGGGCGGGGAACACCGCTAGTGGTTCTGTGGTTACTTCCTGCATGATACCACGAGATACTTCCTCCTGTATGACACC
TTATTCCCATTCACCCCGGACAGATTCTGGCTACACAGGCTTTTCAAACCACCAGAATCAGTTCAGCCATGTGCCTCTC
AATAATTTTTTCACTGACTCTTTACTTTCTGGGGCAACCAATGGACATGCTTTTGAAACCAAGCCGGAATTTGAAAGGA
GATCTTCCAGCATTGCAGTTCTACGGATGAAAGCCAAAGAGCATGCTGCCAATATTTCCTGGGCTATGTAATATAGCTG
TACCCTTTCTTCATATCTTTTTTTTTAAATAGTAAACTGAAAGCATTTTTATTTTCCATATTTAAAGGACACAACAATA
AGCTGCCGTGTGTGGAATGCTAGAAATCACAATATACGTGATGTCTGCTTACAAAAATGCAAAATCATATTTAACAATA
AAACTTAAGAATAAACCATATAGATTTACCATGCATCAAGTTCAACAAACCCTCTTTGTTTTAGTTTTTATATAGAAAC
ATGTTTTGTTGTACAACTTGATGAAATATGATTATAGAACTTGCAAAAAAGAATAAACCAATTAAGCAAATATGTCTAT
GCCATTGGTTTTTAGCAATTCTGTATACAAAATTAATACTTTTCAAATTAATACTTCATAATGGAAGAACTCTGTAAAG
GAAAATTCATTTCTTGTATTAGAACCATGATGTAAATCTCTAAGCACACCATGCAGAGAAGGAAATACATGATCACTAT
GTTGTAGGTGGAATTTGTAGACCTAAGTTTCTCAATACTGTGCTGTGGCTCTGAGCCAGCTTGCTGCTTTTCTAAATGC
ATGTAGAGCTCACTGGAGTTGTAGCAGTGCATAACTAACATAATGAGAAGGTAGTCCTTCATTTTATGAACTCAAGTGT
ATTCCTATTACAGATTATGAGATTTTTAATAAAGATATCACTAAAAGCAGAATCAGTTTTTAACAGAGTTTCAAAGAAG
TGCACAAATTGTGTAAATCAACTAGTTTAAATGAAATATTTAAGGTTTCAGATAGAATATCTTGAAACTTACAAACCAG
CitationH. Thompson, J.S. Griffiths, G. Jeffery, I.M. McGonnell. The retinal pigment epithelium of the eye regulates the development of scleral cartilage. Dev Biol. 2010 November 1; 347(1-13): 40-52.
Copyright2010
CommentsAs insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #XM_425445.3 ).
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
13-18
stage 18
stage 18
Eye
 
19-23
stage 23
stage 23
Eye
 

Entry 4

GEISHA IdALX1.McGonnell.2011Data SourcePublication
Complete cDNA Template Probeshow
GTCTAGGGGAAGAGGCTCTCCGACAGCCTTAGATGATTATGGATTTTCTGAGTGAGAAGTTTGCCCTGAAGAGCCAGCC
GAGCAAGAACAGTGACTTTTACATGGGAGCAGGAGGCACTTTGGAGCACGTTATGGAAACTTTGGACAATGAGTCCTTT
TATAGCAAAACGTCAGGCAGCAAATGTGTGCAGGCCTTCAACCCTCTGCAAAGGGCTGAGCATCATGTGAGGCTGGACA
GGACATCACCCTGCCAAGACAACAACGTGAACTATGGGATTACTAAAGTGGAAGGACAGCCTCTTCACACAGAGCTCAA
CAGGCCCTTGGACAACTGCAACAATCTGAGGATGTCTCCGGTGAAGGGGATGCAGGAGAAGGGGGAACTGGATGAACTG
GGTGATAAGTGTGACAGCAATGTCTCCAGCAGTAAGAAGAGGAGACACAGAACAACTTTCACCAGTTTGCAGCTGGAGG
AACTGGAGAAAGTCTTCCAGAAAACTCATTACCCTGATGTCTACGTGAGGGAGCAGCTAGCTCTGAGGACAGAGCTCAC
CGAGGCCAGAGTCCAGGTTTGGTTCCAGAATAGAAGAGCAAAATGGAGGAAAAGAGAACGCTATGGGCAGATCCAGCAA
GCTAAGAGCCATTTTGCTGCCACTTATGATATATCTGTTCTTCCAAGGACTGACAGCTATCCTCAGATTCAGAACAATC
TGTGGGCGGGGAACACCGCTAGTGGTTCTGTGGTTACTTCCTGCATGATACCACGAGATACTTCCTCCTGTATGACACC
TTATTCCCATTCACCCCGGACAGATTCTGGCTACACAGGCTTTTCAAACCACCAGAATCAGTTCAGCCATGTGCCTCTC
AATAATTTTTTCACTGACTCTTTACTTTCTGGGGCAACCAATGGACATGCTTTTGAAACCAAGCCGGAATTTGAAAGGA
GATCTTCCAGCATTGCAGTTCTACGGATGAAAGCCAAAGAGCATGCTGCCAATATTTCCTGGGCTATGTAATATAGCTG
TACCCTTTCTTCATATCTTTTTTTTTAAATAGTAAACTGAAAGCATTTTTATTTTCCATATTTAAAGGACACAACAATA
AGCTGCCGTGTGTGGAATGCTAGAAATCACAATATACGTGATGTCTGCTTACAAAAATGCAAAATCATATTTAACAATA
AAACTTAAGAATAAACCATATAGATTTACCATGCATCAAGTTCAACAAACCCTCTTTGTTTTAGTTTTTATATAGAAAC
ATGTTTTGTTGTACAACTTGATGAAATATGATTATAGAACTTGCAAAAAAGAATAAACCAATTAAGCAAATATGTCTAT
GCCATTGGTTTTTAGCAATTCTGTATACAAAATTAATACTTTTCAAATTAATACTTCATAATGGAAGAACTCTGTAAAG
GAAAATTCATTTCTTGTATTAGAACCATGATGTAAATCTCTAAGCACACCATGCAGAGAAGGAAATACATGATCACTAT
GTTGTAGGTGGAATTTGTAGACCTAAGTTTCTCAATACTGTGCTGTGGCTCTGAGCCAGCTTGCTGCTTTTCTAAATGC
ATGTAGAGCTCACTGGAGTTGTAGCAGTGCATAACTAACATAATGAGAAGGTAGTCCTTCATTTTATGAACTCAAGTGT
ATTCCTATTACAGATTATGAGATTTTTAATAAAGATATCACTAAAAGCAGAATCAGTTTTTAACAGAGTTTCAAAGAAG
TGCACAAATTGTGTAAATCAACTAGTTTAAATGAAATATTTAAGGTTTCAGATAGAATATCTTGAAACTTACAAACCAG
CitationMcGonnell IM, Graham A, Richardson J, Fish JL, Depew MJ, Dee CT, Holland PW, Takahashi T.. Evolution of the Alx homeobox gene family: parallel retention and independent loss of the vertebrate Alx3 gene. Evol Dev. 2011 July; 13(4): 343–351.
CopyrightCopyright © 2011 Wiley Periodicals, Inc.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
19-23
stage 23
stage 23
Eye
Face Mesenchyme
Head Mesenchyme
 

Mouse

EmageMGI:104621
EurexpressMGI:104621
MGI GXDMGI:104621

Frog

Xenbase853094

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-050419-191, ZDB-GENE-050419-191
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