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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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BMP2
bone morphogenetic protein 2

The human orthologue of this gene is associated
with the following human diseases:

Gene

Official Symbol	BMP2
Official Full Name	bone morphogenetic protein 2
CGNC ID	49116
also known as	bone morphogenetic protein 2\|BMP-2, Bone morphogenetic protein 2 precursor, BMP2
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_204358
Polypeptide	NP_989689
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.3950

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	33432			FBgn0000490
Human	650	ENSG00000125845	MIM:235200	MIM:112261
Mouse	12156	ENSMUSG00000027358	All phenotypic alleles (8):Targeted, knock-out(3) Targeted, other(5)	MGI:88177
Xenopus	548717, 378780, 397873			481828
Zebrafish	30632, 30631	ENSDARG00000041430, ENSDARG00000013409	ZDB-GENE-980526-474, ZDB-GENE-980526-388	ZFIN:ZDB-GENE-980526-474, ZFIN:ZDB-GENE-980526-388

Gene Ontology

Molecular Function	cytokine activity, growth factor activity
Biological Process	cardiac epithelial to mesenchymal transition, cartilage development, growth, ossification, more...
Cellular Component	extracellular space

Links to other databases

Entrez Gene	378779
Ensembl Gene	ENSGALG00000008830
KEGG	gga:378779

Entry 1

GEISHA Id	BMP2.UAlinear	Data Source	GEISHA ISH Analysis
Complete cDNA Template Probe	show GGTTCGCTGAAGCGCCCCGAGGACCTCCTGGGCGAGTTCGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGC CGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATGTTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTA CCCGCTGGAGAGGGCCGCCTGCCGCGCCAACACCGTGTGCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAA ACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTTAACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAAC TCCAGATTTTTCCGGGGGAGCAGGTGCACGAAGCCTTTGAGAGCAACAGCAGCTACCATCACCGTATTAATATTTATGA AATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCACGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCA AGTAAATGGGAAAGTTCTGATGTAACGCCAGCTGTTTTGAGGTGGATTGCACACGGACAACCTAACCATGGGTTTGTGG TGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAGAGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGA AGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTGGGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAA AAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATACAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATG ACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTACAGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCT GGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGACTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCT TGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTACCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATC AAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGACACCGCGAGTGTATCGGGACAAATGCAAAAGAAAAAGCTGACAC TTTAATATTTCCCG

Stage

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1-3

stage 3

Early Mesoderm
Epiblast
Primitive Streak

4-6

stage 4

stage 5

stage 6

Anterior Intestinal Portal
Early Mesoderm
Endoderm
Epiblast
Germinal Crescent
Head Process
Lateral Plate Mesoderm
Primitive Streak

7-12

stage 7

stage 8

stage 10

stage 11

stage 12

Anterior Intestinal Portal
Cardiovascular
Endoderm
Forebrain
Head Mesenchyme
Heart
Lateral Plate Mesoderm
Primitive Streak
extraembryonic endoderm

st 8+

13-18

stage 13

stage 14

stage 15

Anterior Intestinal Portal
Endoderm
Forebrain
Head Mesenchyme
Lateral Plate Mesoderm
Primitive Streak

19-24

stage 20

stage 21

stage 23

Allantois
Anterior/Second Heart Field
Head Mesenchyme
Heart
Hindbrain
Leg
Leg AER
Leg Mesenchyme
Limb Buds
Pharyngeal Arches and Clefts
Wing
Wing AER
Wing Mesenchyme

25-30

stage 25

Heart
Leg Mesenchyme
Wing Mesenchyme

Left
Right

31-42

stage 42

Feathers/Scutae
Surface Ectoderm

Entry 2

GEISHA Id	Bmp2.Kamimura.2004	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Kamimura, M, Matsumoto, K, Koshiba-Takeuchi, K, Ogura, T. Vertebrate Crossveinless 2 Is Secreted and Acts as an Extracellular Modulator of the BMP Signalling Cascade. Dev Dyn. 2004 Jul;230(3):434-45.
Copyright	Wiley-Liss, Inc. 2004
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # AY237249).

Stage

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13-18

stage 17

Atria
Heart
Myocardium
Ventricles

25-29

stage 29

Wing Mesenchyme

Entry 3

GEISHA Id	Bmp2.Huillard.2004	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Huillard E, Marx M. Localized Expression of drm/gremlin in the Central Nervous System of the Chicken Embryo. Dev Dyn. 2004 Mar;229(3):688-94.
Copyright	Copyright © 2004 Wiley-Liss, Inc.
Comments	Insufficient information provided to verify exact probe sequence. Sequence shown is entire coding region from Accession # NM_204358.

Stage

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31-40

stage 36

stage 40

Spinal Cord
Telencephalon

cervical level

Entry 4

GEISHA Id	Bmp2.Lincoln.2004	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Lincoln J, Alfieri CM, Yutzey KE. Development of heart valve leaflets and supporting apparatus in chicken and mouse embryos. Dev Dyn. 2004 Jun;230(2):239-50.
Copyright	Wiley-Liss, Inc. 2004
Comments	Insufficient information provided to verify exact probe sequence. Sequence shown is entire coding region from Accession # NM_204358.

Stage

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25-30

stage 29

Atria
Heart
Valves

31-36

stage 36

Atria
Heart
Valves

Entry 5

GEISHA Id	BMP2.Chapman.2002	Data Source	Publication
Complete cDNA Template Probe	show GGTTCGCTGAAGCGCCCCGAGGACCTCCTGGGCGAGTTCGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGC CGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATGTTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTA CCCGCTGGAGAGGGCCGCCTGCCGCGCCAACACCGTGTGCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAA ACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTTAACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAAC TCCAGATTTTTCCGGGGGAGCAGGTGCACGAAGCCTTTGAGAGCAACAGCAGCTACCATCACCGTATTAATATTTATGA AATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCACGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCA AGTAAATGGGAAAGTTCTGATGTAACGCCAGCTGTTTTGAGGTGGATTGCACACGGACAACCTAACCATGGGTTTGTGG TGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAGAGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGA AGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTGGGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAA AAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATACAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATG ACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTACAGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCT GGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGACTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCT TGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTACCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATC AAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGACACCGCGAGTGTATCGGGACAAATGCAAAAGAAAAAGCTGACAC TTTAATATTTCCCG
Citation	Chapman SC, Schubert FR, Schoenwolf GC, Lumsden A. Analysis of spatial and temporal gene expression patterns in blastula and gastrula stage chick embryos. Dev Biol. 2002 May 1;245(1):187-99.
Copyright	2002 Elsevier Science (USA). All rights reserved.

Stage

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4-5

stage 4

stage 5

Ectoderm
Endoderm
Neural Plate/Tube
Primitive Streak

BMP2:blue
Chd:red

Entry 6

GEISHA Id	Bmp2.Andree.1998	Data Source	Publication
Complete cDNA Template Probe	show `GGACCTCCTGGGCGAGTTCGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTC GTCATCCCCCCCTACATGTTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCA GCCGCGCCAACACCGTGTGCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACG ACGTTTCTTCTTTAATTTAACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAG GTGCACGAAGCCTTTGAGAGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCA CCTCCAAGGACCCTGTCACGAGACT`
Citation	Andrée B, Duprez D, Vorbusch B, Arnold H-H, Brand T. BMP-2 induces ectopic expression of cardiac lineage markers and interferes with somite formation in chicken embryos. Mech Dev. 1998 Jan;70(1-2):119-31.
Copyright	Copyright © 1998 Elsevier Science Ireland Ltd. All rights reserved

Stage

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4-6

stage 4

Lateral Plate Mesoderm
Primitive Streak

7-9

stage 7

stage 8

stage 9

Anterior Intestinal Portal
Endoderm
Foregut
Pharynx
Primitive Streak

Expression in pharyngeal floor
Expression in pharyngeal floor and cardiogenic endoderm
Expression in pharyngeal floor and promyocardium.
Expression in the cardiogenic endoderm.

Entry 7

GEISHA Id	Bmp2.Ghatpande.2006	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Ghatpande S, Brand T, Zile M, Evans T. Bmp2 and Gata4 function additively to rescue heart tube development in the absence of retinoids. Dev Dyn. 2006 Aug;235(8):2030-9.
Copyright	Copyright © 2006 Wiley-Liss, Inc.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204358).

Stage

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4-6

stage 6

Hensen's Node
Lateral Plate Mesoderm
Primitive Streak

Quail embryo

Entry 8

GEISHA Id	BMP2.Michon.2007	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Michon F, Charveron M, Dhouailly D. Dermal condensation formation in the chick embryo: requirement for integrin engagement and subsequent stabilization by a possible notch/integrin interaction. Dev Dyn. 2007 Mar;236(3):755-68.
Copyright	Copyright © 2007 Wiley-Liss, Inc.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204358).

Stage

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25-30

stage 30

Feathers/Scutae
Surface Ectoderm

Entry 9

GEISHA Id	Bmp2.Schlueter.2006	Data Source	GEISHA ISH Analysis
Complete cDNA Template Probe	show `TAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAGAGCAACAGCAGC TACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCACGAGACTTTTGG ACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAGGTGGATTGCACA CGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAGAGGCACGTTAGG ATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTGGGCATGATGGCA AGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATACA`
Comments	For the detection of Bmp2, a 460 bp fragment encoding the divergent propeptide domain of BMP2 was used (Andrée et al., 1998), generated by RT-PCR using primers 5′-TAATGAGGAGTCTGTCACC-3′ and 5′-TGTATTTGTGGCGCTTACGC-3′

Stage

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13-17

stage 13

stage 17

Myocardium
Sinus Venosus

Entry 10

GEISHA Id	BMP2.Kruithof.2006	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGA
Citation	Kruithof BP, van Wijk B, Somi S, Kruithof-de Julio M, Pérez Pomares JM, Weesie F, Wessels A, Moorman AF, van den Hoff MJ. BMP and FGF regulate the differentiation of multipotential pericardial mesoderm into the myocardial or epicardial lineage. Dev Biol. 2006 Jul 15;295(2):507-22. Epub 2006 Apr 3.
Copyright	Copyright © 2006 Elsevier B.V. All rights reserved.
Comments	Authors indicated the probe cDNA was provided by Dr. P. Brickell (Francis et al., [1994]), who indicated "The longest chicken Bmp-2 cDNA clone had an insert of 1120 bp ... (and they used) nucleotides 1-797 ... as a template." Although the full length BMP2 gene is 1179 nt and thus the probe cannot be precisely known, we took the first 797 of the full length clone to be this probe.

Stage

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13-16

stage 16

Splanchnic Mesoderm

peri-proepicardial mesoderm

Entry 11

GEISHA Id	Bmp2.Bonafede.2006	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Bonafede A, Köhler T, Rodriguez-Niedenführ M, Brand-Saberi B. BMPs restrict the position of premuscle masses in the limb buds by influencing Tcf4 expression. Dev Biol. 2006 Nov 15;299(2):330-44. Epub 2006 Jun 15.
Copyright	Copyright © 2006 Elsevier B.V. All rights reserved.
Comments	The following probes were used: Sf/Hgf (Thery et al., 1995), qPax3, MyoD and Myf5, Lbx1, Bmp2 and Bmp4, Tcf4. Probes used in this study were kindly provided by Claudio Stern, Gabrielle Kardon, Christophe Marcelle, Bruce M. Paterson, Susanne Dietrich and Paul Brickell. Thus insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc # NM_204358).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

19-24

stage 24

Wing Mesenchyme

posterior

Entry 12

GEISHA Id	Bmp2.Nissim.2006	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGA
Citation	Nissim S, Hasso SM, Fallon JF, Tabin CJ. Regulation of Gremlin expression in the posterior limb bud. Dev Biol. 2006 Nov 1;299(1):12-21. Epub 2006 May 26.
Copyright	Copyright © 2006 Elsevier B.V. All rights reserved.
Comments	DIG-labeled probes were generated for Gremlin (Capdevila et al., 1999), Shh (Riddle et al., 1993), Bmp2 (Francis et al., 1994)... Francis et al reported: "The longest chicken Bmp-2 cDNA clone had an insert of 1120 bp and was designated p5. ... To construct a template for the synthesis of Bmp-2-specific probes, nucleotides 1-797 of p5 were amplified by PCR." Although the full length clone is 1179nt, so the exact probe cannot be determined, the first 797nt of NM_204358 are included here as the putative probe.

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

19-22

stage 22

Wing Mesenchyme

posterior

Entry 13

GEISHA Id	Bmp2.Klewer.2006	Data Source	Publication
Complete cDNA Template Probe	show AACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCACGA GACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTCTGATGTAACGCCAGCTGTTTTGAGGTG GATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAGAGG CACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTGGGC ATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATACAG TTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTACAGT GCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAAC
Citation	Klewer SE, Yatskievych T, Pogreba K, Stevens MV, Antin PB, Camenisch TD. Has2 expression in heart forming regions is independent of BMP signaling. Gene Expr Patterns. 2006 Jun;6(5):462-70. Epub 2006 Feb 3.
Copyright	Reprinted with permission from Elsevier. Copyright © 2005 Elsevier B.V. All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (X75914).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

7-12

stage 8

Early Mesoderm
Primitive Streak
Splanchnic Mesoderm

Cardiac crescent

19-24

stage 24

Atria
Outflow Tract
Ventricles

AV canal

Entry 14

GEISHA Id	BMP2.Yamada.2000	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Yamada M, Revelli JP, Eichele G, Barron M, Schwartz RJ. Expression of chick Tbx-2, Tbx-3, and Tbx-5 genes during early heart development: evidence for BMP2 induction of Tbx2. Dev Biol. 2000 Dec 1;228(1):95-105.
Copyright	Reprinted with permission from Elsevier. Copyright © 2000 Elsevier B.V. All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204358).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

4-6

stage 5

Primitive Streak
Splanchnic Mesoderm

Cardiogenic Region

7-12

stage 8

stage 10

Heart Tube
Primitive Streak
Splanchnic Mesoderm
Veins

Cardiogenic Region
Vitellin Veins

stage 19

Atria
Heart Tube
Ventricles

Atrioventricular Junction

all

Figure 1 compares expression patterns of Tbx2, Tbx3, Tbx5 and bmp2 in early chick embryos. Figure includes HH stages 5-8, 10, 11, 16, 19 and 20.

Entry 15

GEISHA Id	Bmp2.Maden.2007	Data Source	Publication
Forward cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Maden M, Blentic A, Reijntjes S, Seguin S, Gale E, Graham A. (2007). Retinoic acid is required for specification of the ventral eye field and for Rathke's pouch in the avian embryo. Int J Dev Biol. 2007;51(3):191-200.
Copyright	"Reprinted from Int. J. Dev. Biol., 51, Maden M, Blentic A, Reijntjes S, Seguin S, Gale E, Graham A, Retinoic acid is required for specification of the ventral eye field and for Rathke's pouch in the avian embryo, 191-200, Copyright (2007), with permission from Copyright © 2007 UBC Press". All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_204358). Images are quail, but sequence and map shown are chick.

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

19-24

stage 20

Pharyngeal Arches and Clefts
Pituitary (Rudiment)

quail

31-44

stage 44

Pharyngeal Arches and Clefts
Pituitary (Rudiment)

quail

Entry 16

GEISHA Id	BMP2.Sakiyama.2000	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Sakiyama J, Yokouchi Y, Kuroiwa A. Coordinated expression of Hoxb genes and signaling molecules during development of the chick respiratory tract. Dev Biol. 2000 Nov 1;227(1):12-27.
Copyright	Reprinted with permission from Elsevier. Copyright © 2000 Elsevier B.V. All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204358).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

19-24

stage 20

stage 24

Lung
Unlabeled

Bmp-2 not expressed in the lung at this stage.
Main Bronchus Mesenchymal Layer

25-30

stage 27

stage 29

Lung

Dorsal Lung Mesenchyme

31-34

stage 34

Lung

Bronchial Tree
Figure 3 compares the expressions of Bmp-2 and Bmp-4 in the developing chick respiratory tract at HH stages 20, 24, 27, 29 and 34.

Entry 17

GEISHA Id	Bmp2.Bardot.2004	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Bardot B, Lecoin L, Fliniaux I, Huillard E, Marx M, Viallet JP. Drm/Gremlin, a BMP antagonist, defines the interbud region during feather development. Int J Dev Biol. 2004;48(2-3):149-56.
Copyright	"Reprinted from Int. J. Dev. Biol., 48, Bardot B, Lecoin L, Fliniaux I, Huillard E, Marx M, Viallet JP, Drm/Gremlin, a BMP antagonist, defines the interbud region during feather development, 149-56, Copyright (2004), with permission from Copyright © 2004 UBC Press". All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc #NM_204358).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

19-24

stage 22

Feathers/Scutae

31-44

stage 44

Feathers/Scutae

Comparison with other genes

Entry 18

GEISHA Id	Bmp2.Christ.2002	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Christ B, Brand-Saberi B. Limb muscle development. Int J Dev Biol. 2002;46(7):905-14.
Copyright	"Reprinted from Int. J. Dev. Biol., 46, Christ B, Brand-Saberi B, Limb muscle development, 905-14, Copyright (2002), with permission from Copyright © 2002 UBC Press". All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_204358).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

19-24

stage 22

Wing

Comparison with other genes

31-44

stage 44

Somites
Wing

Comparison with other genes

Entry 19

GEISHA Id	Bmp2.Chapman.2008	Data Source	Direct Submission
Complete cDNA Template Probe	show GGTTCGCTGAAGCGCCCCGAGGACCTCCTGGGCGAGTTCGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGC CGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATGTTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTA CCCGCTGGAGAGGGCCGCCTGCCGCGCCAACACCGTGTGCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAA ACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTTAACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAAC TCCAGATTTTTCCGGGGGAGCAGGTGCACGAAGCCTTTGAGAGCAACAGCAGCTACCATCACCGTATTAATATTTATGA AATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCACGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCA AGTAAATGGGAAAGTTCTGATGTAACGCCAGCTGTTTTGAGGTGGATTGCACACGGACAACCTAACCATGGGTTTGTGG TGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAGAGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGA AGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTGGGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAA AAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATACAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATG ACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTACAGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCT GGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGACTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCT TGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTACCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATC AAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGACACCGCGAGTGTATCGGGACAAATGCAAAAGAAAAAGCTGACAC TTTAATATTTCCCG
Comments	Images and probe information provided by Susan Chapman

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

1-3

stage 3

Area Opaca
Area Pellucida
Head Process
Hensen's Node
Kohler's Sickle
Lateral Plate Mesoderm
Primitive Streak

Bmp2:blue
Chd:red
prechordal mesoderm

4-6

stage 4

stage 5

stage 6

Head Process
Lateral Plate Mesoderm
Primitive Streak
Splanchnic Mesoderm

Bmp2:blue
Chd:red
cardiac crescent

7-12

stage 7

stage 8

stage 9

stage 11

Anterior Intestinal Portal
Endoderm
Foregut
Primitive Streak
Splanchnic Mesoderm

cardiac crescent

13-17

stage 17

Heart
Isthmus/MHB
Pharyngeal Arches and Clefts
Pituitary (Rudiment)
Primitive Streak

Rathke's pouch, AV Canal

Entry 20

GEISHA Id	Bmp2.Holleville.2007	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGA
Citation	Holleville N, Matéos S, Bontoux M, Bollerot K, Monsoro-Burq AH. Dlx5 drives Runx2 expression and osteogenic differentiation in developing cranial suture mesenchyme. Dev Biol. 2007 Apr 15;304(2):860-74.
Copyright	Reprinted with permission from Elsevier. Copyright © 2007 Elsevier B.V. All rights reserved.
Comments	Authors indicated the probe sequence was from the clone identified in Francis-West et al., 1994. This clone has NCBI acc# NM_204358.1. This paper said: nucleotides 1-797 (were)cloned into pBluescript SK+ ...Antisense RNA probes specific for chicken Bmp-2 transcripts were synthesized with T3 RNA polymerase, using HindIII-linearized p5.1 as a template.

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

31-38

stage 38

Face Mesenchyme

Mandibular Osteoblasts

Entry 21

GEISHA Id	BMP2.Allen.2001	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Allen SP, Bogardi JP, Barlow AJ, Mir SA, Qayyum SR, Verbeek FJ, Anderson RH, Francis-West PH, Brown NA, Richardson MK (2001). Misexpression of noggin leads to septal defects in the outflow tract of the chick heart. Dev Biol. 2001 Jul 1;235(1):98-109.
Copyright	Copyright © 2001 Academic Press. All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204358).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

19-24

stage 20

stage 24

Aorta
Heart
Outflow Tract

Aortic Sac
Atrioventricular Canal

Entry 22

GEISHA Id	BMP2.McKinnell.2004	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	McKinnell IW, Turmaine M, Patel K (2004). Sonic Hedgehog functions by localizing the region of proliferation in early developing feather buds. Dev Biol. 2004 Aug 1;272(1):76-88.
Copyright	Copyright © 2004 Published by Elsevier Inc.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204358).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

25-30

stage 30

Feathers/Scutae

Control

Entry 23

GEISHA Id	BMP2.Lopez-Sanchez.2009	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Lopez-Sanchez C, Garcia-Masa N, Gañan CM, Garcia-Martinez V. Movement and commitment of primitive streak precardiac cells during cardiogenesis. Int J Dev Biol. 2009;53(8-10):1445-55.
Copyright	Reprinted from Int. J. Dev. Biol. Copyright (2009), with permission from UBC Press. All rights reserved.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_204358.1).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

4-6

stage 6

Early Endoderm

7-8

stage 7

stage 8

Early Endoderm
Splanchnic Mesoderm

Entry 24

GEISHA Id	BMP2.Roddy.2011	Data Source	Publication
Complete cDNA Template Probe	show CGGCCTCATGCCGGAGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGAC CTCCTGGGCGAGTTCGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCA TCCCCCCCTACATGTTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCG CGCCAACACCGTGTGCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGT TTCTTCTTTAATTTAACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGC ACGAAGCCTTTGAGAGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTC CAAGGACCCTGTCACGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACG CCAGCTGTTTTGAGGTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGA ACAGTGCCTCCA
Citation	Roddy KA, Prendergast PJ, Murphy P. Mechanical influences on morphogenesis of the knee joint revealed through morphological, molecular and computational analysis of immobilised embryos. PLoS One. 2011 Feb 28;6(2):e17526.
Copyright	PLoS One is an open access journal.
Comments	The cDNA template used to generate the probe was obtained from EST - ChEST367j4 as described.

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

25-27

stage 27

Leg Bones

il, intermediate layer
p, patella

Entry 25

GEISHA Id	BMP2.Parkinson.2010	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Parkinson N, Collins MM, Dufresne L, Ryan AK. Expression patterns of hormones, signaling molecules, and transcription factors during adenohypophysis development in the chick embryo. Dev Dyn. 2010 Apr;239(4):1197-210.
Copyright	Copyright © 2010 Wiley-Liss, Inc.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (acc # NM_204358.1).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

19-24

stage 23

Unlabeled

rp, Rathke's pouch

31-40

stage 36

stage 40

Pituitary (Rudiment)

Entry 26

GEISHA Id	BMP2.Bothe.2011	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Bothe I, Tenin G, Oseni A, Dietrich S., Dynamic control of head mesoderm patterning., Development. 2011 Jul;138(13):2807-21.
Copyright	Permission from the authors and the Company of Biologists Ltd. Copyright held by the authors.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_204358.1 ).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

4-6

stage 5

Head Process
Lateral Plate Mesoderm
Primitive Streak

7-12

stage 7

stage 10

Anterior Intestinal Portal
Head Mesenchyme
Head Process

stage 13

Anterior Intestinal Portal
Head Mesenchyme

Entry 27

GEISHA Id	BMP2.Cui.2009	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Cui C, Cheuvront TJ, Lansford RD, Moreno-Rodriguez RA, Schultheiss TM, Rongish BJ. Dynamic positional fate map of the primary heart-forming region. Dev Biol. 2009 Aug 15;332(2):212-22. Epub 2009 Jun 2.
Copyright	Copyright © 2009 Published by Elsevier Inc
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_204358.1).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

4-6

stage 5

Head Process
Headfold
Lateral Plate Mesoderm

stage 7

Head Process
Lateral Plate Mesoderm

Entry 28

GEISHA Id	BMP2.Vargesson.2009	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Vargesson N, Laufer E.. Negative Smad Expression and Regulation in the Developing Chick Limb. PLoS ONE. 2009; 4(4): e5173.
Copyright	Copyright Vargesson, Laufer. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

19-20

stage 20

Wing

Entry 29

GEISHA Id	BMP2.Gamer.2008	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Gamer LW, Ho V, Cox K, Rosen V.. Expression and Function of BMP3 During Chick Limb Development. Dev Dyn. 2008 June; 237(6): 16911698.
Copyright	Copyright © 2008 Wiley-Liss, Inc.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_204358.1 ).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

19-24

stage 24

Leg

Entry 30

GEISHA Id	BMP2.Ishii.2010	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Ishii Y, Garriock RJ, Navetta AM, Coughlin LE, Mikawa T.. BMP Signals Promote Proepicardial Protrusion Necessary for Recruitment of Coronary Vessel and Epicardial Progenitors to the Heart. Dev Cell. 2010 August 17; 19(2): 307316.
Copyright	Copyright © 2010 Elsevier Inc. All rights reserved.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204358.1 ).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

13-17

stage 14

stage 16

stage 17

Heart

Entry 31

GEISHA Id	BMP2.Houghton.2005	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Houghton L, Lindon C, Morgan BA. The ectodysplasin pathway in feather tract development. Development. 2005 Mar;132(5):863-72. Epub 2005 Jan 26.
Copyright	copyright is held by the authors. Published by the Company of Biologists Ltd.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204358.1).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

stage 31

Feathers/Scutae

Entry 32

GEISHA Id	BMP2.Chang.2004	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Chang W, Brigande JV, Fekete DM, Wu DK. The development of semicircular canals in the inner ear: role of FGFs in sensory cristae. Development. 2004 Sep;131(18):4425-34. Epub 2004 Aug 11.
Copyright	Copyright is held by the authors. Published by the Company of Biologists Ltd.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #NM_204358.1 ).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

19-24

stage 21

stage 23

Ear/Otic Placode

31-35

stage 35

Ear/Otic Placode

Entry 33

GEISHA Id	BMP2.Wood.2010	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Wood JL, Hughes AJ, Mercer KJ, Chapman SC. Analysis of chick (Gallus gallus) middle ear columella formation. BMC Dev Biol. 2010; 10: 16. Published online 2010 February 16.
Copyright	Copyright ©2010 Wood et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204358.1).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

25-30

stage 26

stage 28

Face Mesenchyme

31-35

stage 31

stage 34

stage 35

Face Mesenchyme

Entry 34

GEISHA Id	BMP2.Tao.2002	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Tao H, Yoshimoto Y, Yoshioka H, Nohno T, Noji S, Ohuchi H. FGF10 is a mesenchymally derived stimulator for epidermal development in the chick embryonic skin. Mech Dev. 2002 Aug;116(1-2):39-49.
Copyright	Copyright © 2012 Elsevier B.V. All rights reserved.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204358.1).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

stage 31

Feathers/Scutae

Entry 35

GEISHA Id	BMP2.Schlange.2002	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Schlange T, Arnold HH, Brand T. BMP2 is a positive regulator of Nodal signaling during left-right axis formation in the chicken embryo. Development. 2002 Jul;129(14):3421-9.
Copyright	Copyright is held by the authors. Published by the Company of Biologists Ltd.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_204358.1).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

stage 7

Lateral Plate Mesoderm
Pharynx

bmp2 colored red in picture , mesoderm and underlying pharyngeal endoderm
mesoderm and and pharyngeal endoderm , BMP2 expression is colored dark blue in photo

Entry 36

GEISHA Id	BMP2.mercader.2000	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Mercader N, Leonardo E, Piedra ME, Martínez-A C, Ros MA, Torres M. Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes. Development. 2000 Sep;127(18):3961-70.
Copyright	© The Company of Biologists Limited 2000
Comments	According to the authors, "Riboprobes cBmp2, cBmp4 and cBmp7 were kindly provided by C. Tabin and B. Houston." As information provided was insufficient to verify exact sequence used to synthesize probe, the sequence was obtained from NCBI (acc# NM_204358.1).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

19-22

stage 22

Limb Buds

left side = control side
right side = FGF1 bead

Entry 37

GEISHA Id	BMP2.Manning.2007	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Manning L, Ohyama K, Saeger B, Hatano O, Wilson SA, Logan M, Placzek M. Regional morphogenesis in the hypothalamus: a BMP-Tbx2 pathway coordinates fate and proliferation through Shh downregulation. Dev Cell. 2006 Dec;11(6):873-85.
Copyright	Copyright © 2006 Elsevier Inc. All rights reserved.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_204358.1

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

7-12

stage 8

stage 10

Hypothalamus

13-15

stage 15

Hypothalamus

Entry 38

GEISHA Id	BMP2.Zou.1997	Data Source	GEISHA ISH Analysis
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Zou H, Wieser R, Massagué J, Niswander L. Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage. Genes Dev 1997 Sep 1;11(17):2191-203.
Copyright	Copyright © 1997, Cold Spring Harbor Laboratory Press
Comments	Author indicated the probe could be found in another publication; Francis et al. 1994. The indicated probe sequence is included here.

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

stage 31

Leg Bones

metatarsals

Entry 39

GEISHA Id	BMP‐2.Belecky-Adams.2001	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Belecky-Adams T, Adler R. Developmental expression patterns of bone morphogenetic proteins, receptors, and binding proteins in the chick retina. J Comp Neurol. 2001 Feb 19;430(4):562-72.
Copyright	Copyright © 2001 Wiley‐Liss, Inc.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence was obtained from NCBI (NM_204358.1).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

13-18

stage 18

Ectoderm

25-30

stage 29

Retina

31-44

stage 34

stage 44

Retina

Entry 40

GEISHA Id	BMP2.Anderson.2020	Data Source	Direct Submission
Complete cDNA Template Probe	show GGTTCGCTGAAGCGCCCCGAGGACCTCCTGGGCGAGTTCGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGC CGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATGTTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTA CCCGCTGGAGAGGGCCGCCTGCCGCGCCAACACCGTGTGCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAA ACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTTAACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAAC TCCAGATTTTTCCGGGGGAGCAGGTGCACGAAGCCTTTGAGAGCAACAGCAGCTACCATCACCGTATTAATATTTATGA AATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCACGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCA AGTAAATGGGAAAGTTCTGATGTAACGCCAGCTGTTTTGAGGTGGATTGCACACGGACAACCTAACCATGGGTTTGTGG TGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAGAGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGA AGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTGGGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAA AAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATACAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATG ACGTGGG
Comments	Images provided by Claire Anderson. The publication of Liem et al. 1995 (Liem Jr., K.F, Tremml G, Roelink H, Jessell T.M. Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm. Cell. 1995; 82: 969-979. PMID: 7553857 ) was referred for the probe information. Authors indicated further probe information could be found in another publication (Francis PH, Richardson MK, Brickell PM, Tickle C. Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb. Development. 1994 Jan;120(1):209-18. PMID: 8119128). The indicated probe sequence was extracted from NCBI (GenBank: X75914.1).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

4-6

stage 5

Lateral Plate Mesoderm
Primitive Streak

prechordal plate

7-10

stage 8

stage 10

Endoderm
Foregut
Lateral Plate Mesoderm
Pharynx
Primitive Streak
Splanchnic Mesoderm

cardiac crescent

Entry 41

GEISHA Id	BMP-2.Wittler.2008	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Wittler L, Saborowski M, Kessel M. Expression of the chick Sizzled gene in progenitors of the cardiac outflow tract. Gene Expr Patterns. 2008 Jul;8(6):471-6. Epub 2008 Feb 29.
Copyright	Copyright © 2008 Elsevier B.V.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_204358 )

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

13-16

stage 16

Aorta
Cardiovascular
Outflow Tract
Splanchnic Mesoderm

all

Entry 42

GEISHA Id	Bmp2.Singh.2016	Data Source	Publication
Complete cDNA Template Probe	show ATGGTTGCCGCCACCCGCTCCCTCCTGGCGCTGCTGCTCTGCCGGGTGCTGCTGGGCGGCGCGGCCGGCCTCATGCCGG AGGTGGGACGGCGGCGCTTCAGCGAACCGGGCCGCGCCGCCTCGGCCGCGCAGCGCCCCGAGGACCTCCTGGGCGAGTT CGAGCTGCGCCTGCTCCACATGTTCGGGCTGAAGCGGCGGCCGAGCCCCGGCAAGGACGTCGTCATCCCCCCCTACATG TTGGACCTCTATCGCCTGCACGCCGGCCAGCAGCTGGGCTACCCGCTGGAGAGGGCCGCCAGCCGCGCCAACACCGTGT GCAGCTTCCACCACGAAGAAGTTTTGGAAGAACTGCCAGAAACAAGTGGGAAAACAGCACGACGTTTCTTCTTTAATTT AACTTCCATCCCTAATGAGGAGTCTGTCACCTCAGCTGAACTCCAGATTTTTCGGGAGCAGGTGCACGAAGCCTTTGAG AGCAACAGCAGCTACCATCACCGTATTAATATTTATGAAATTATGAAGCCAGCCACAGCCACCTCCAAGGACCCTGTCA CGAGACTTTTGGACACCAGGTTGGTGCATCATAATGCAAGTAAATGGGAAAGTTTTGATGTAACGCCAGCTGTTTTGAG GTGGATTGCACACGGACAACCTAACCATGGGTTTGTGGTGGAGGTGGTTCACTTGGACAAAGAGAACAGTGCCTCCAAG AGGCACGTTAGGATTAGCAGGTCTTTACATCAGGATGAAGATAGCTGGTCTCAGCTCAGGCCGTTGTTAGTGACGTTTG GGCATGATGGCAAGGGACACCCGCTCCACAAAAGAGAAAAGCGTCAAGCGAAACACAAACAGCGTAAGCGCCACAAATA CAGTTGCAAAAGGCATCCGTTGTATGTGGACTTCAATGACGTGGGGTGGAATGACTGGATTGTTGCCCCGCCGGGGTAC AGTGCCTTTTACTGCCATGGGGAATGTCCTTTTCCGCTGGCAGATCACCTAAACTCAACAAACCATGCCATTGTTCAGA CTTTGGTCAATTCGGTGAATTCCAAAATCCCCAAGGCTTGCTGTGTGCCGACAGAACTGAGTGCTATCTCAATGCTCTA CCTTGATGAGAACGAAAAGGTCGTACTAAAGAACTATCAAGATATGGTTGTGGAGGGCTGCGGGTGCCGCTGA
Citation	Singh PN, Ray A, Azad K, Bandyopadhyay A. A comprehensive mRNA expression analysis of developing chicken articular cartilage. Gene Expr Patterns. 2016 Jan;20(1):22-31.
Copyright	Copyright © 2015 Elsevier B.V. All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence was obtained from NCBI (NM_204358)

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

25-30

stage 28

Limb Buds

31-38

stage 31

stage 34

stage 36

stage 38

Limb Buds

all

Data from NCBI Unigene EST Profile
Unigene ID: Gga.3950

Mouse

Emage	MGI:88177
Eurexpress	MGI:88177
MGI GXD	MGI:88177

Frog

Xenbase

481828

Fruit Fly

BDGP	FBgn0000490

Zebra Finch

ZEBrA

Zebrafish

ZFIN	ZDB-GENE-980526-474, ZDB-GENE-980526-388

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BMP2bone morphogenetic protein 2

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Entry 42

Mouse

Frog

Fruit Fly

Zebra Finch

Zebrafish

BMP2
bone morphogenetic protein 2