|
| SIM1 SIM bHLH transcription factor 1 | The human orthologue of this gene is associated with the following human disease: |
Gene | Official Symbol | SIM1 | Official Full Name | SIM bHLH transcription factor 1 | CGNC ID | 49663 | also known as | single-minded homolog 1|single-minded family bHLH transcription factor 1, SIM1 , single-minded homolog 1 | gene type | protein-coding |
| Genomic Map | | Sequence Information | | Gene Expression | | Orthology | | Gene Ontology | Molecular Function | | Biological Process | | Cellular Component | |
| Links to other databases | |
Entry 1GEISHA Id | SIM1.UApcr | Data Source | GEISHA ISH Analysis | Forward cDNA Template Primer | GCGGGGGCTACAAGGTCATCC | Reverse cDNA Template Primer | AATTAACCCTCACTAAAGGGGGAGAGGCTGTGTCGGTGAGG | cDNA Template Length | 719 | Forward cDNA Template Probe | show NCCCGGAGAGGCGGAGGGCTCACCCCCTGGCTCTCAGGTCAGATTCAGATCTCTCAGTGTGAAATCCGGAACACTGTGG GTATGGTGATGTCCTTGATTTTGACTTTGTGCTCGAGAGGCGAGATTTGCTTCCCTTTCTATTATCCGTTATGGTCGGA GTTGAATTTGCGTATGAGAATGCCGGCTTGGTAGCTGTGACCTGATCCAAGGAGAGCTGTAGTCCTTTATATTCAGTAT CCGTAAGGACGTAGTTAACGCTGACGATGCAGTGCGGGCGTGACGAGCGGCTGTTGTGCACGATGGTGGCATAGCTCTG CACCCACACCCAGCCGCCGTGCTTGGCCAGGAAGCGGTAGTACTTGGTGGTCACCTGGCCCTTCACCAGCAACAAGTGA TGCGCGCATCGCAGGTGGAAGGTGTCACAGCCGTGTACGTGATGGTAAAGGGTCTTCTCGATCAGGTCCTGGGGCTCGT ACCCGGTGAGCTCGGCCACCCTGGAGTCTAGGAAGATGAGCTTCATGTCCAGGCTAGCCCGGAACATGAACATGTTGCT GTGCAGCTTGATCTCTGTCACTGCGCTGGGAGGCAACGAGTGGCCCACGGCGACCAAACCGACGTTTTGGTAGCAGCCG TCGAAAGGGGACATGTCCAGGCTGTACTGGCGGATCTTCAGGTAGCCGCTGCAGTGGATGACCTTGTAGCCCCCGCAAA A |
Entry 2GEISHA Id | Sim1.Ahmed.2006 | Data Source | Publication | Complete cDNA Template Probe | show ATGAAAGAGAAGTCCAAAAATGCTGCCCGGACTAGGCGGGAGAAAGAAAACAGCGAGTTTTATGAACTGGCTAAATTAC TGCCCCTGCCCTCGGCCATCACCTCCCAGCTGGACAAAGCATCCATAATCAGGCTCACCACCAGCTACCTCAAGATGCG GGTGGTTTTCCCAGAAGGACTGGGAGAAGCCTGGGGCCACTCCAGCCGCACCAGCCCGCTGGATAACGTCGGACGGGAG CTGGGATCGCATCTTTTGCAGACGCTGGACGGTTTCATATTCGTGGTGGCTCCGGATGGGAAGATCATGTACATCTCGG AGACCGCCTCGGTGCACCTGGGCCTGTCTCAGGTAGAGCTGACCGGCAACAGCATTTACGAGTACATCCACCCCGCCGA CCACGACGAGATGACGGCGGTGCTTACAGCCCACCAGCCCTACCACTCCCACTTCGTGCAGGAGTATGAGATCGAGCGG TCCTTTTTCCTGCGGATGAAATGCGTACTGGCCAAGAGGAACGCGGGGCTGACCTGCGGGGGCTACAAGGTCATCCACT GCAGCGGCTACCTGAAGATCCGCCAGTACAGCCTGGACATGTCCCCTTTCGACGGCTGCTACCAAAACGTCGGTTTGGT CGCCGTGGGCCACTCGTTGCCTCCCAGCGCAGTGACAGAGATCAAGCTGCACAGCAACATGTTCATGTTCCGGGCTAGC CTGGACATGAAGCTCATCTTCCTAGACTCCAGGGTGGCCGAGCTCACCGGGTACGAGCCCCAGGACCTGATCGAGAAGA CCCTTTACCATCACGTACACGGCTGTGACACCTTCCACCTGCGATGCGCGCATCACTTGTTGCTGGTGAAGGGCCAGGT GACCACCAAGTACTACCGCTTCCTGGCCAAGCACGGCGGCTGGGTGTGGGTGCAGAGCTATGCCACCATCGTGCACAAC AGCCGCTCGTCACGCCCGCACTGCATCGTCAGCGTTAACTACGTCCTTACGGATACTGAATATAAAGGACTACAGCTCT CCTTGGATCAGGTCACAGCTACCAAGCCGGCATTCTCATACGCAAATTCAACTCCGACCATAACGGATAATAGAAAGGG AAGCAAATCTCGCCTCTCGAGCACAAAGTCAAAATCAAGGACATCACCATACCCACAGTATTCCGGATTTCACACTGAG AGATCTGAATCTGACCATGAGAGCCAGTGGGGTGGGAGCCCCCTCACCGACACAGCCTCTCCCCAGCTGTTGGAGCCCA CAGACAGGCCGAGCTCCCAGCATCACGATGTCTCCTGTGCCTACAGACAGTACTCGGACCGCAGTGCTCTCTGCTATGG TTTTGCACTAGACCACTCCAGGCTGGGCGATGACAGACATTTCCATACTCAGGCCTGTGAGGGAGGCAGATGTGAAGCT GGCAGATATTTCCTTGGCACACCACAGCCGGGGAGGGAAGGCTGGTGGGGCTCCCGATCAGCCTTGCCCCTGACTAAGT CATCCCCTGAAAGCAGAGAGGCGTATGAAAACAGTATGCCCCACATAACTTCAGTGCACAGGATTCACGGGAGAGGACA CTGGGATGAGGACAGTGTTGTTAGCTCTCCTGATCCTGGCTCTGCCAGTGAATCTGGTGACCGATACCGTGCTGAACAG TATCAGAGCAGCCCACATGAGCCCAGCAAAATTGAAACTCTAATAAGAGCCACCCAGCAAATGATCAAAGAGGAAGAAA ACAGGCTACAGCTACGGAAAACAACCCCTGATCCACTGATCTCCATTAATGGCACAGGGAAGAAACACACAATTTGTTT TGCAAACTACCCCCAGCAACAGTTGGCAGGGGATATCTGCCGCGTTCCGACGGTTGCCAACACTCCTCCTTGTGAACAC ATCCAGCAACGGGATGGAAAAATTATGAGCCCTCATGAAAATGACTATGACAACAGTCCCACAACATTGTCTAGGATAA GCAGTCCCAATTCTGACCGAATATCAAAATCTAGCTTGGTACTAGCTAAAGACTACCTGAATACAGACATGTCCCCTCA TCAAACTCCAGGTGATCATCCAGCAGCTTCTCCAAATTATTACAACTCCCACAGGCAGTACTTTGATAAGCATGCTTAC ACGCTAACTGGGTATGCCCTGGAGCATCTATACGACACTGAAGCCATTAGAAACTATTCACTAGGCTGCAATGGATCAC ACTTTGATGTGACTTCTCACTTAAGGATGCAGCAAGATCCAGCACAAGGACACAAAGGGACATCCGTTATAATAACCAA TGGAAGCTGA | Citation | Ahmed MU, Cheng L, Dietrich S. Establishment of the epaxial-hypaxial boundary in the avian myotome. Dev Dyn. 2006 Jul;235(7):1884-94. | Copyright | Copyright © 2006 Wiley-Liss, Inc. | Comments | Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (XM_419817). |
Stage | Image (click image to view full size) | Location (click to highlight) | Comments (click to highlight) | 19-24 | | stage 22 | | stage 22 | | stage 24 | | Dermatome Myotome
| 25 | | stage 25 | | Dermatome Myotome
|
Entry 3GEISHA Id | Sim1.Bothe.2007 | Data Source | Publication | Complete cDNA Template Probe | show ATGAAAGAGAAGTCCAAAAATGCTGCCCGGACTAGGCGGGAGAAAGAAAACAGCGAGTTTTATGAACTGGCTAAATTAC TGCCCCTGCCCTCGGCCATCACCTCCCAGCTGGACAAAGCATCCATAATCAGGCTCACCACCAGCTACCTCAAGATGCG GGTGGTTTTCCCAGAAGGACTGGGAGAAGCCTGGGGCCACTCCAGCCGCACCAGCCCGCTGGATAACGTCGGACGGGAG CTGGGATCGCATCTTTTGCAGACGCTGGACGGTTTCATATTCGTGGTGGCTCCGGATGGGAAGATCATGTACATCTCGG AGACCGCCTCGGTGCACCTGGGCCTGTCTCAGGTAGAGCTGACCGGCAACAGCATTTACGAGTACATCCACCCCGCCGA CCACGACGAGATGACGGCGGTGCTTACAGCCCACCAGCCCTACCACTCCCACTTCGTGCAGGAGTATGAGATCGAGCGG TCCTTTTTCCTGCGGATGAAATGCGTACTGGCCAAGAGGAACGCGGGGCTGACCTGCGGGGGCTACAAGGTCATCCACT GCAGCGGCTACCTGAAGATCCGCCAGTACAGCCTGGACATGTCCCCTTTCGACGGCTGCTACCAAAACGTCGGTTTGGT CGCCGTGGGCCACTCGTTGCCTCCCAGCGCAGTGACAGAGATCAAGCTGCACAGCAACATGTTCATGTTCCGGGCTAGC CTGGACATGAAGCTCATCTTCCTAGACTCCAGGGTGGCCGAGCTCACCGGGTACGAGCCCCAGGACCTGATCGAGAAGA CCCTTTACCATCACGTACACGGCTGTGACACCTTCCACCTGCGATGCGCGCATCACTTGTTGCTGGTGAAGGGCCAGGT GACCACCAAGTACTACCGCTTCCTGGCCAAGCACGGCGGCTGGGTGTGGGTGCAGAGCTATGCCACCATCGTGCACAAC AGCCGCTCGTCACGCCCGCACTGCATCGTCAGCGTTAACTACGTCCTTACGGATACTGAATATAAAGGACTACAGCTCT CCTTGGATCAGGTCACAGCTACCAAGCCGGCATTCTCATACGCAAATTCAACTCCGACCATAACGGATAATAGAAAGGG AAGCAAATCTCGCCTCTCGAGCACAAAGTCAAAATCAAGGACATCACCATACCCACAGTATTCCGGATTTCACACTGAG AGATCTGAATCTGACCATGAGAGCCAGTGGGGTGGGAGCCCCCTCACCGACACAGCCTCTCCCCAGCTGTTGGAGCCCA CAGACAGGCCGAGCTCCCAGCATCACGATGTCTCCTGTGCCTACAGACAGTACTCGGACCGCAGTGCTCTCTGCTATGG TTTTGCACTAGACCACTCCAGGCTGGGCGATGACAGACATTTCCATACTCAGGCCTGTGAGGGAGGCAGATGTGAAGCT GGCAGATATTTCCTTGGCACACCACAGCCGGGGAGGGAAGGCTGGTGGGGCTCCCGATCAGCCTTGCCCCTGACTAAGT CATCCCCTGAAAGCAGAGAGGCGTATGAAAACAGTATGCCCCACATAACTTCAGTGCACAGGATTCACGGGAGAGGACA CTGGGATGAGGACAGTGTTGTTAGCTCTCCTGATCCTGGCTCTGCCAGTGAATCTGGTGACCGATACCGTGCTGAACAG TATCAGAGCAGCCCACATGAGCCCAGCAAAATTGAAACTCTAATAAGAGCCACCCAGCAAATGATCAAAGAGGAAGAAA ACAGGCTACAGCTACGGAAAACAACCCCTGATCCACTGATCTCCATTAATGGCACAGGGAAGAAACACACAATTTGTTT TGCAAACTACCCCCAGCAACAGTTGGCAGGGGATATCTGCCGCGTTCCGACGGTTGCCAACACTCCTCCTTGTGAACAC ATCCAGCAACGGGATGGAAAAATTATGAGCCCTCATGAAAATGACTATGACAACAGTCCCACAACATTGTCTAGGATAA GCAGTCCCAATTCTGACCGAATATCAAAATCTAGCTTGGTACTAGCTAAAGACTACCTGAATACAGACATGTCCCCTCA TCAAACTCCAGGTGATCATCCAGCAGCTTCTCCAAATTATTACAACTCCCACAGGCAGTACTTTGATAAGCATGCTTAC ACGCTAACTGGGTATGCCCTGGAGCATCTATACGACACTGAAGCCATTAGAAACTATTCACTAGGCTGCAATGGATCAC ACTTTGATGTGACTTCTCACTTAAGGATGCAGCAAGATCCAGCACAAGGACACAAAGGGACATCCGTTATAATAACCAA TGGAAGCTGA | Citation | Bothe I, Ahmed MU, Winterbottom FL, von Scheven G, Dietrich S. Extrinsic versus intrinsic cues in avian paraxial mesoderm patterning and differentiation. Dev Dyn. 2007 Sep;236(9):2397-409. | Copyright | Copyright © 2007 Wiley-Liss, Inc. | Comments | Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (XM_419817). |
Stage | Image (click image to view full size) | Location (click to highlight) | Comments (click to highlight) | 13-18 | | stage 15 | | Sclerotome Somites
| 19-24 | | stage 24 | | stage 24 | | Somites
|
Entry 4GEISHA Id | Sim1.Cheng.2004 | Data Source | Publication | Complete cDNA Template Probe | show ATGAAAGAGAAGTCCAAAAATGCTGCCCGGACTAGGCGGGAGAAAGAAAACAGCGAGTTTTATGAACTGGCTAAATTAC TGCCCCTGCCCTCGGCCATCACCTCCCAGCTGGACAAAGCATCCATAATCAGGCTCACCACCAGCTACCTCAAGATGCG GGTGGTTTTCCCAGAAGGACTGGGAGAAGCCTGGGGCCACTCCAGCCGCACCAGCCCGCTGGATAACGTCGGACGGGAG CTGGGATCGCATCTTTTGCAGACGCTGGACGGTTTCATATTCGTGGTGGCTCCGGATGGGAAGATCATGTACATCTCGG AGACCGCCTCGGTGCACCTGGGCCTGTCTCAGGTAGAGCTGACCGGCAACAGCATTTACGAGTACATCCACCCCGCCGA CCACGACGAGATGACGGCGGTGCTTACAGCCCACCAGCCCTACCACTCCCACTTCGTGCAGGAGTATGAGATCGAGCGG TCCTTTTTCCTGCGGATGAAATGCGTACTGGCCAAGAGGAACGCGGGGCTGACCTGCGGGGGCTACAAGGTCATCCACT GCAGCGGCTACCTGAAGATCCGCCAGTACAGCCTGGACATGTCCCCT | Citation | Cheng L, Alvares LE, Ahmed MU, El-Hanfy AS, Dietrich S. The epaxial-hypaxial subdivision of the avian somite. Dev Biol. 2004 Oct 15;274(2):348-69. | Copyright | Reprinted from Developmental Biology, Volume 274, Issue 2, Louise Cheng, Lúcia E. Alvares, Mohi U. Ahmend, Amira S. El-Hanfy, and Susanne Dietrich, The epaxial-hypaxial subdivision of the avian somite, Pages 348-369, Copyright 2004, with permission from Elsevier.
Copyright © 2004 Elsevier B.V. All rights reserved. | Comments | Authors indicate the probe is from Pourquie et al., 1996 who said they cloned a 600bp fragment with an upstream primer MKEKSKN and 3'RACE. The 5' end fragment is Acc# U40058. The 600 bp sequence here was extracted from XM_419817 using this information. |
Stage | Image (click image to view full size) | Location (click to highlight) | Comments (click to highlight) | 19-20 | | stage 20 | | |
Entry 5GEISHA Id | Sim1.Agarwala.2005 | Data Source | Publication | Complete cDNA Template Probe | show ATGAAAGAGAAGTCCAAAAATGCTGCCCGGACTAGGCGGGAGAAAGAAAACAGCGAGTTTTATGAACTGGCTAAATTAC TGCCCCTGCCCTCGGCCATCACCTCCCAGCTGGACAAAGCATCCATAATCAGGCTCACCACCAGCTACCTCAAGATGCG GGTGGTTTTCCCAGAAGGACTGGGAGAAGCCTGGGGCCACTCCAGCCGCACCAGCCCGCTGGATAACGTCGGACGGGAG CTGGGATCGCATCTTTTGCAGACGCTGGACGGTTTCATATTCGTGGTGGCTCCGGATGGGAAGATCATGTACATCTCGG AGACCGCCTCGGTGCACCTGGGCCTGTCTCAGGTAGAGCTGACCGGCAACAGCATTTACGAGTACATCCACCCCGCCGA CCACGACGAGATGACGGCGGTGCTTACAGCCCACCAGCCCTACCACTCCCACTTCGTGCAGGAGTATGAGATCGAGCGG TCCTTTTTCCTGCGGATGAAATGCGTACTGGCCAAGAGGAACGCGGGGCTGACCTGCGGGGGCTACAAGGTCATCCACT GCAGCGGCTACCTGAAGATCCGCCAGTACAGCCTGGACATGTCCCCTTTCGACGGCTGCTACCAAAACGTCGGTTTGGT CGCCGTGGGCCACTCGTTGCCTCCCAGCGCAGTGACAGAGATCAAGCTGCACAGCAACATGTTCATGTTCCGGGCTAGC CTGGACATGAAGCTCATCTTCCTAGACTCCAGGGTGGCCGAGCTCACCGGGTACGAGCCCCAGGACCTGATCGAGAAGA CCCTTTACCATCACGTACACGGCTGTGACACCTTCCACCTGCGATGCGCGCATCACTTGTTGCTGGTGAAGGGCCAGGT GACCACCAAGTACTACCGCTTCCTGGCCAAGCACGGCGGCTGGGTGTGGGTGCAGAGCTATGCCACCATCGTGCACAAC AGCCGCTCGTCACGCCCGCACTGCATCGTCAGCGTTAACTACGTCCTTACGGATACTGAATATAAAGGACTACAGCTCT CCTTGGATCAGGTCACAGCTACCAAGCCGGCATTCTCATACGCAAATTCAACTCCGACCATAACGGATAATAGAAAGGG AAGCAAATCTCGCCTCTCGAGCACAAAGTCAAAATCAAGGACATCACCATACCCACAGTATTCCGGATTTCACACTGAG AGATCTGAATCTGACCATGAGAGCCAGTGGGGTGGGAGCCCCCTCACCGACACAGCCTCTCCCCAGCTGTTGGAGCCCA CAGACAGGCCGAGCTCCCAGCATCACGATGTCTCCTGTGCCTACAGACAGTACTCGGACCGCAGTGCTCTCTGCTATGG TTTTGCACTAGACCACTCCAGGCTGGGCGATGACAGACATTTCCATACTCAGGCCTGTGAGGGAGGCAGATGTGAAGCT GGCAGATATTTCCTTGGCACACCACAGCCGGGGAGGGAAGGCTGGTGGGGCTCCCGATCAGCCTTGCCCCTGACTAAGT CATCCCCTGAAAGCAGAGAGGCGTATGAAAACAGTATGCCCCACATAACTTCAGTGCACAGGATTCACGGGAGAGGACA CTGGGATGAGGACAGTGTTGTTAGCTCTCCTGATCCTGGCTCTGCCAGTGAATCTGGTGACCGATACCGTGCTGAACAG TATCAGAGCAGCCCACATGAGCCCAGCAAAATTGAAACTCTAATAAGAGCCACCCAGCAAATGATCAAAGAGGAAGAAA ACAGGCTACAGCTACGGAAAACAACCCCTGATCCACTGATCTCCATTAATGGCACAGGGAAGAAACACACAATTTGTTT TGCAAACTACCCCCAGCAACAGTTGGCAGGGGATATCTGCCGCGTTCCGACGGTTGCCAACACTCCTCCTTGTGAACAC ATCCAGCAACGGGATGGAAAAATTATGAGCCCTCATGAAAATGACTATGACAACAGTCCCACAACATTGTCTAGGATAA GCAGTCCCAATTCTGACCGAATATCAAAATCTAGCTTGGTACTAGCTAAAGACTACCTGAATACAGACATGTCCCCTCA TCAAACTCCAGGTGATCATCCAGCAGCTTCTCCAAATTATTACAACTCCCACAGGCAGTACTTTGATAAGCATGCTTAC ACGCTAACTGGGTATGCCCTGGAGCATCTATACGACACTGAAGCCATTAGAAACTATTCACTAGGCTGCAATGGATCAC ACTTTGATGTGACTTCTCACTTAAGGATGCAGCAAGATCCAGCACAAGGACACAAAGGGACATCCGTTATAATAACCAA TGGAAGCTGA | Citation | Agarwala S, Aglyamova GV, Marma AK, Fallon JF, Ragsdale CW. Differential susceptibility of midbrain and spinal cord patterning to floor plate defects in the talpid2 mutant. Dev Biol. 2005 Dec 1;288(1):206-20. Epub 2005 Oct 21. | Copyright | Copyright © 2005 Elsevier Inc. All rights reserved. | Comments | According to the authors, "Digoxigenin
(DIG)- and fluorescein-labeled riboprobes were synthesized from chick cDNA plasmids..." As information provided was insufficient to verify exact sequence used to synthesize probe,the sequence below was obtained from NCBI (XM_419817). |
Stage | Image (click image to view full size) | Location (click to highlight) | Comments (click to highlight) | 25-26 | | stage 26 | | Neural Plate/Tube Spinal Cord
|
Entry 6
| Data from NCBI Unigene EST Profile Unigene ID: Gga.31324 |
MouseFrogFruit FlyZebra FinchZebrafish
|
|