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ITGB2
integrin subunit beta 2

The human orthologue of this gene is associated
with the following human disease:

Gene

Official Symbol	ITGB2
Official Full Name	integrin subunit beta 2
CGNC ID	49690
also known as	CD18, integrin beta-2\|integrin beta 2 subunit\|integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
gene type	protein-coding

Genomic Map

Sequence Information

Gene Expression

In Situ Hybridization

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	3689	ENSG00000160255	MIM:116920	MIM:600065
Mouse	16414	ENSMUSG00000000290	All phenotypic alleles (5):Chemically induced(1) Targeted, knock-out(2) Targeted, other(2)	MGI:96611
Xenopus	100492659, 379708, 378687			988512
Zebrafish	557797	ENSDARG00000016939	ZDB-GENE-110411-4	ZFIN:ZDB-GENE-110411-4

Gene Ontology

Links to other databases

GEISHA Id	ITGB2.Oliveira.2010	Data Source	Publication
Complete cDNA Template Probe	show CAATAAGATACAGCTGACTCCCCAGGAGGTGCATCTGAAGCTGAGGATAAGGGAGCCTGCTGAATTTGATGTGAAGTTT CGTCGTGCTACGGGGTACCCAATTGATATCTACTACCTCATGGACCTCTCCTATTCCATGCTGGATGACCTAGAGAACG TGAAGAAGCTGGGAGGACAACTGCTTAGAGCCCTGGAGAGCACCACACCCTCTCGCCGCATAGGTTTTGGTTCCTTTGT GGACAAGACTGTACTGCCTTTTGTCAACACACATCCTGAGAAGCTGAAGAACCCTTGCCCCAACAAGGACAGTAATTGC CAGCCTCCCTTCGCCTTCAAGCACATCCTCTCACTGACTGACAATGCCGAGAAGTTTGAGAGTGAAGTGGGGAAGCAGT TCATCTCAGGGAACCTGGATGCCCCAGAAGGGCTGGATGCCATGATGCAGGCGGCAGTGTGTGGAGACTTGATTGGCTG GCGCAATGTGACCCGATTGCTGGTGTATGCAACTGATGATGGCTTCCACTTCGCTGGTGATGGCAAGCTCGGGGGCATT TTGACCCCCAATGATGGCCAGTGCCACTTGGAGGACAACATGTACAAAAAGAGCAATGAGTTTGACTATCCTTCTGTTG GCCAGCTGGTCCAGAAACTTGCTGAAAACAACATTCAGCCCATTTTTGCTGTCACCAGCAAGATGGTGGATGTTTACAA AAAACTCAGTGATATGATCCCAA
Citation	Oliveira LA, Baker RK, Klewer SE, Kitten GT. Expression of beta 2 integrin (CD18) in embryonic mouse and chicken heart. Braz J Med Biol Res. 2010 Jan;43(1):25-35.
Comments	The cDNA template used to generate the probe was obtained by PCR as described in Oliveira et al.