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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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ZEB1
zinc finger E-box binding homeobox 1

The human orthologue of this gene is associated
with the following human diseases:

Gene

Official Symbol	ZEB1
Official Full Name	zinc finger E-box binding homeobox 1
CGNC ID	5487
also known as	TCF8, zinc finger E-box-binding homeobox 1\|TCF-8\|delta EF1\|delta-crystallin enhancer-binding factor\|deltaEF1\|transcription factor 8 (represses interleukin 2 expression), Zinc finger E-box-binding homeobox 1 , Transcription factor 8, Delta- crystallin enhancer-binding factor (Delta EF1). , Zfhx1a
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_205131
Polypeptide	NP_990462
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.3548

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	6935	ENSG00000148516	MIM:613270	MIM:189909
Mouse	21417	ENSMUSG00000024238	All phenotypic alleles (4):Targeted, knock-out(1) Targeted, other(3)	MGI:1344313
Xenopus	548525, 444391			484654
Zebrafish	114425, 100004929	ENSDARG00000013207, ENSDARG00000016788	ZDB-GENE-010621-1, ZDB-GENE-070912-124	ZFIN:ZDB-GENE-010621-1, ZFIN:ZDB-GENE-070912-124

Gene Ontology

Molecular Function	E-box binding, metal ion binding, sequence-specific DNA binding, more...
Biological Process	negative regulation of transcription, DNA-templated, positive regulation of neuron differentiation, more...transcription, DNA-templated
Cellular Component	nucleus

Links to other databases

Entrez Gene	396029
Ensembl Gene	ENSGALG00000007260
KEGG	gga:396029

Entry 1

GEISHA Id	ChEST935j15	Data Source	GEISHA ISH Analysis
Forward cDNA Template Probe	show TCAGATAACGTAGCTGGGTCCATGCTATCTTTATAAGAGTCTCTAAACACAGCAGTGGGAAGGCAAGTAGTAAAGAGGC GAGTAGAAAGCTGGAAAAAAGAGCAGGAAGAAAAGTAGATGAAACAAAGTGGATTTTTCCAATTGATATACGTGTAGTC AGCAAGTTTGGTACATAAGGCACCTGTCCCAGGCAAGATTTTGGAATGATTTGCCTTTTACCTTTGACATGATACAAGG GCTTGTGCATGAAAGCGAACGTGAAAGCTCATTGATCTTAAATTTCCATCAGGATAGAAGAGCTGAAATGGTTTTGAGT TTCAATAATTTTTATTGCAAGAAAAATGCCTCTTTTTCTAATCTATTTATATTCACACTTGTTTTGTACTCTGAGTTGC ATCTGAGAATCTGTTTATCTTTTGATGTTCATTTTTCCTAAGAAGGTTACAAATACCTTTGTAGTTTAGCACCGTGCCC TTGTATCCCTATGCAAGAAACCCAGGCTGACAATGCTGAGAGCAAACTGTTAAATACAATTACTTGTTGTTGGCAATAC ATTCACCAACAGCATATTATAATGAAAGCAGCAGCACAGAGTTTAAAATATTACGTTTAAGGAATCCTTTTTTTGTTTG TTTGTTTGTTTTTGTGCTTTATTTTCTAGGTAAAAGACCTCATGAGTGTGGAATCTGTAAAAAAGCCTTCAAACACAAA CACCATTTGATCGAACACATGCGACTGCATTCTGGGGAGAAACCCTACCAATGTGACAAATGCGGGAAGCGCTTCTCAC ACTCGGGGTCGTACTCTCAGCACATGAATCATCGCTACTCCTATTGCAA

Stage

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Location (click to highlight)

Comments (click to highlight)

13-18

stage 16

Widespread Expression

19-20

stage 20

Somites
Widespread Expression

Entry 2

GEISHA Id	ZEB1.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	GAGGAGGAGGAAGAAAAGGACG
Reverse cDNA Template Primer	ATTAACCCTCACTAAAGGTGGCACTTACAGCACACAGGTC	cDNA Template Length	1082
Forward cDNA Template Probe	show CCCCATCATCCCACCACACAGACAGGGCTTGATAGGCCAAGGAAGAAAAAGCCTCATATCATATCCCTCAAATTGGTAC TACCTACCTCAAAACACAAATACCCACCACGGAATTTTGACGAACTTTGCCTGTCCTTACCGGGAATTAAACACGTGTA AAGTCCCCGGCAAACAGAAACTCAACAACCAACCTTTTCAACCACCTTTTTAACCCCCTGGATAAAAAAACTTCGTTTC TCCAACCACCGGCTTCCTAAGGGCAAAAAAAACCCTTAAAAGGAAAAAAGGGCTCAACAACAAAACCCAAGGTAAAAAC CCCCACCTTTCAGGTTGAATTTACAAAGGTACCCCAACCCTGTTAAAGGTTTCGGCCAAAGGGAATTCCGTATGGCAAA ATTTCCCCCTTTTAAAAAACCTAAAAAAACGGGGACCCGATTTAAGAAATGTTTTTCCCCTTAAAAAACAAAAAACCAA AAAAACCCCCCCCAATTGGGCCCGGCTAAAAAAAATTTATTGACCCCCTAAACAGGAAAATTTTAAATGCGGGAAAAAA AAAAAAAAGGGGCCCCAAGGATGTTGTTTATAAAAAAAAAAAGGGGTTTCCCCCCAACCACCGGTGATAAAACCCCTTT TTTTCTCCCCAAAAAAACACCCCGGGGGTTTTTTTCACAAAAACCCCCGGCCCCGCGGGGGGAAAAAAAAACGTTGTTT CCCCACAAAATTTTTAAGAAAAACGGGGGGGGAAAAAAAATA

Stage

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Location (click to highlight)

Comments (click to highlight)

1-3

stage 3

Unlabeled

Stages 3 & 4.

4-6

stage 4

stage 5

Early Mesoderm
Epiblast
Neural Plate/Tube
Primitive Streak

7-12

stage 8

Area Opaca
Lateral Plate Mesoderm
Neural Plate/Tube

extremely faint staining
very faint staining

13-18

stage 14

stage 16

Forebrain
Hindbrain
Midbrain

trapping

19-21

stage 20

stage 21

Entry 3

GEISHA Id	Zfhx1a.Tylzanowski.2003	Data Source	Publication
Complete cDNA Template Probe	show GCGAGAGGATCATGGCGGATGGCCCCAGGTGTAAGCGCAGGAAGCAGGCGAACCCGAGGCGCAACAACGTCACCAATTA CAATAACGTGATAGAAGCAAACTCAGATTCAGATGACGAAGATAAATTGCATATAGTGGAAGAAGAAAGTATAACTGAT GCAGCAGACTGCGATGCAAGTGTGCCAGAAGATGACTTGCCAACAGACCACACCGTGTTACCAGAAAACAGTGAGAGGG AAGGGAGCACAAACAGCTGCTGGGAAGATGAAGGAAAAGAAACAAAGGAAATCCTGGGGCCTGAAGCTCAGTCAGATGA AGTTGGATGTACAGTAAAAGAAGATGAATGTGATTCTGATGCAGAAAATGAACAGAACCATGACCCTAATGTTGAAGAA TTCCTTCAACAAGAAGATACAGCTGTTATTTACCCTGAAGCACCTGAGGAGGACCAGAGACAAGGCACACCAGAAGCTA GTGGTCAGGATGAAAATGGAACGCCCGATGCATTTTCCCAGCTGCTCACCTGCCCGTACTGTGACAGAGGGTACAAACG CTTCACCTCTCTGAAGGAACACATTAAATACCGCCATGAAAAGAACGAGGATAACTTCAGTTGCTCCCTCTGCAGTTAC ACGTTTGCGTATAGAACACAGCTGGACCGCCACATGACGTCGCACAAGTCAGGACGAGATCAGAGACATGTGACGCAGT CCAGTGGTAATCGAAAATTCAAGTGCACTGAATGTGGAAAAGCTTTTAAATATAAACATCATCTAAAGGAACACCTACG AATTCACAGTGGAGAGAAGCCATATGAGTGCCCAAACTGCAAGAAACGTTTTTCCCATTCTGGTTCATACAGCTCACAC ATAAGCAGTAAGAAGTGTATTGGTTTGATGCCCGTAAAGGGTCGAGCTCGGTCAGGGCTCAAGACGTCTCAGTGCTCCT CCCCTTCCCTTTCTGCATCGCCCGGTAGCCCAGCAAGACCACAGATACGACAAAAGATAGAAAATAAACCCTTGCAAGA GCAACTTCCTGTTAACCAAATTAAAACTGAACCTGTGGATTATGAATTCAAGCCCATAGTGGTTGCTTCAGGAATTAAT TGTTCGACCCCTTTGCAGAATGGGGTTTTTAGTGGTGGTAGCCCGTTGCAGGCAACCAGTTCTCCTCAGGGTGTGGTGC AAGCTGTTGTTCTGCCAACAGTGGGTCTGGTGTCTCCCATAAGCATCAACTTAAGTGACATTCAAAATGTACTTAAAGT GGCAGTGGATGGTAATGTAATAAGGCAAGTATTGGAAAACAATCACGCTAATCTTGCATCCAAAGAACAAGAAACAATC AGCAATGCATCTATACAACAAGCTGGCCATTCCCTCATTTCAGCTATCAGTCTTCCTTTGGTTGACCAAGATGGGACAA CCAAAATTATCATCAACTACAGCTTGGAGCAGCCAAGTCAACTTCAGGTTGTTCCCCAAAATCTAAAAAAAGAACATTC TGTTCCTACAAACAGTTGCAAAAATGAAAAGTTACCAGAAGATCTTACGGTGAAGTCTGAGAAAGATAAAAACTTTGAA GGAGAGACCAACGATAGCACTTGTCTTCTTTGTGATGACTGTCCAGGAGATCTTAATGCACTTCAAGAATTAAAGCACT ATGAAACAAAAAATCCTCCTCAGCTTCCCCAGTCCAGTGGAACAGAAGCTGAGAAGCCCAGCTCCCCTGCCCCATCAGA AACTGGGGAGAACAACTTATCTCCTGGTCAGCCACCCTTAAAGAACCTTTTATCGCTCCTAAAAGCATATTATGCATTA AATGCACAACCAAGCGCAGAAGAGCTTTCAAAAATCGCCGATTCCGTGAACCTACCACTGGATGTGGTAAAAAAGTGGT TTGAAAAAATGCAAGCTGGACAAATTTCTGTGCAGTCTTCTGGACCATCTTCTCCTGAACAAGTTAAAATAAGCAGTCC CACAGATAACGATGATCAAGCAGCAACTACAAATGAGAGTGAACCCCAGAACAGCACAAACAACTCACAAAATCCGGCC AATACAAGTAAATCTCAGACTTCATCAGGGGGATCAACTCAGAATGGTTCGCGCAGTAGCACGCCATCCCCATCACCAC TAAACCTTTCTTCATCAAGAAATTCACAGGGTTATACGTACACAGCAGAGGGTGTACAAGAAGAGCCACAAATGGAACC TCTTGACCTTTCACTACCAAAGCAACATGGAGAACTGTTGGAAAGATCTACCATAACTAGTGTTTACCAGAACAGTGTT TATTCTGTCCAGGAAGAACCTTTGAACTTAACTTGTGCAAAAAAAGAACCACAAAAGGACAACAGTATTACAGACTCTG ATCCTATTGTAAATGTAATCCCACCAAGTGCCAATCCCATAAATATTGCTATACCTACAGTCACTGCCCAGTTACCTAC AATTGTTGCCATTGCTGACCAGAACAGTGTTCCATGCTTGAGAGCTCTTGCTGCCAATAAGCAAACCATTTTGATTCCC CAGGTGGCTTATACGTACTCTACTACAGTTAGTCCTGCAGTTCAGGAAACACCACCAAAACAGACCCAAGCCAACGGAA GTCAGGACGAAAGGCAGGACACTAGCTCAGAAGGAGTATCGAATGTAGAAGATCAAAATGATTCTGATTCAACACCCCC AAAGAAAAAGATGAGAAAGACAGAAAATGGGATGTATGCATGTGATTTGTGTGACAAAATATTCCAGAAGAGCAGCTCA TTATTGAGACATAAGTATGAACACACAGGTAAAAGACCTCATGAGTGTGGAATCTGTAAAAAAGCCTTCAAACACAAAC ACCATTTGATCGAACACATGCGACTGCATTCTGGGGAGAAACCCTACCAATGTGACAAATGCGGGAAGCGCTTCTCACA CTCGGGGTCGTACTCTCAGCACATGAATCATCGCTACTCCTATTGCAAAAGAGAGGCAGAGGAGCGTGACAGCACAGAG CAGGAGGAGGTGGGACAGGAGGTGCTCAGCAGCGAGCATGCTGGTGCCAGAGCATCGCCATCGCAGATCGACTCCGATG AGAGAGAGAGTCTAACCAGGGAAGAAGAGGAAGATAGTGAAAAAGAGGAAGAGGAGGAGGAAGAAAAGGACGTAGAAGG ACTTCAGGAAGAAAAAGAATGTAGAAAACTACAAGATGTAGAGGAGGAAGAAGAAGTAGAAGAAGAAGAAGAAGAAGAG GAAGGGAAAACTGAAGGTAACAAGAACGATGACGTTGTAAATCGAGCAAGCAATGCAGAACCAGAAGTTATACAGAGCA ATGGGCAGGTGTCAGAAGAAAAAACAAATAAAGCTTAAATGATAGTTTTTTCTATATGGAAAAAAATAAATCAGTAATG AAGATCGTTCTATATTATACATGCTTTTCATGGAAACACGGTAGCCTGCATACTGTGATTTCTGTTCACTACTGTGTAA AAAAATATATATATAAAAAAAAAGAAAAAAGAAAAAAAAAAGAAATCCAGGTGTGCCTGAACCTCAAACTTAGTAATTT TTCACACAGTTTTCAAAGTTAGGAACAAGTTTGTAACATGAAGCAGATTAGAAAAATACAGTGACTCTGGAAGCAAAGG TTTAACAGGTTGTAGGAAACCTGATTTATTAGACAAGCATCTGGCATTGTTTGTTTTATCAGTATTAATTCTCATTCTT ACGTTCATTAATTTTTAAGCTGTACAATTGGGAGAGATTTATATGATTTTTTTTTTTTTTATGGCAAAACATTTCCTAA ATCCGCTTCAGTATTTTATTATGTTTTTAAAATGTGAGAACTTCTGCACTACAGAATTCCCTTCTGCAGAAACCTCTAA CAGTGCTTGGCTACCTTTGTAAATTCAACCTAGAAGGTAGCGGTTATAACATTAGATGTTGTAGTAGAGCATATTATCA TTTAAAGTGTATTGTTAGCCTTAAGAAAGCAGATGATAGAAGAACCGAAGTTTCTTACTCATGTGGTTAAAAATGTAGT TGAAAAGATTGTTGTTGAGTTCTGATTGCAGGGACTAACAGTGTTAATACCGGTAAGGACAGCAAAGTCGTCAAAATCA GTGTTTGTAATTGTGTTTTGAGTATGTAGTAACAATATGAAGGATATGATATGAAGCTTTGTATCTCCTTTGGCCTTAT GCAAGACCTGTGTGCTGTAAGTGCCATTTATCAGTATTACAAAGGCTCTCACCGGCCTTTCTCCAATGCGTGGCCTACA ATAACTAGCATTTGTTGATTTGTATCAAACTTCTAATCTAATCATGGGGGAAAAAACACTCAGCCATCAGAGAAGTAAG AACACTGGTATCTTTCATTATTTAATTATTTGGTGGTATTTTTGGTTAATACCTGACTTGCAGAATTTCTCTACGATAA TTACAAGGGAAATTTTCTAATCTGCTTTATTGCTTTATCAGTTTACTTTAATTTCAGACACATACATGACATGTTATCT GGCTCATAAGTATTTTCAAATGTTAGTTATTATGGACCCCATTTATTAACAATGTTAGCTGATTTTTACCTATCAGTAT TATTTTATTTCTTTTAGTTTATAGATCTGTGCAACATTTTGTACTGTATGTCTCCAAACCTGGCAGTATTAATACCCTT CTTACTGACATATGTACCTTTTTAGTTTTAGAAAACTTTTATATTTATGTGTCTTATTTTTATATTTCTTTATTTATTA CACAGTGTAGTGTATAATACTGTAGTTTGTATTAATACAATAATATATTTTAGTATGAAAATTTGGAAAGTTGATAAGA TTTAAAGTAGAGATGCAATCGGTTCTCTTGCATTGAGATTTGATTTAACAGTGTTATGTTAACATTTATACTTGCCTTG GACTGTAGAACAGATGAATTAAAATGGGAATGTATTAATTTTACAATTGCAATCAATTCATTTTACCTTTACCCAGTTT TTAATATAAAGCTCTTAAATTTTGAAATTCACTGTGTGACTAATAGCATGATGCTCTGCAGTTTTATTAAGAGATTAGC CTAACCATAAAACTCTCATTTCCTTAGTAAGCCAAATTAGAGTAATCTTATAAACAGTGTTGGGAACAACGTTTAACTT TTTTGTGCCAATTTGTTCCTGTATTCATGTATGTATGTTACAAATCTGAAACTTCATTTTTAAGTTCCTTGTTACATCA TGGTCATTTTCTAGTTTTTTACCAGACTCCCCATCTCACAATAAAATACGTCAACAA
Citation	Tylzanowski P, De Valck D, Maes V, Peeters J, Luyten FP. Zfhx1a and Zfhx1b mRNAs have non-overlapping expression domains during chick and mouse midgestation limb development. Gene Expr Patterns. 2003 Mar;3(1):39-42. Erratum in: Gene Expr Patterns. 2003 Jun;3(3):383.
Copyright	Copyright © 2003 Elsevier B.V. All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc # NM_205131).