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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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NHLH1
nescient helix-loop-helix 1

Gene

Official Symbol	NHLH1
Official Full Name	nescient helix-loop-helix 1
CGNC ID	48953
also known as	helix-loop-helix protein 1
gene type	protein-coding

Genomic Map

	Ensembl ID not known
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_204121
Polypeptide	NP_989452
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.141

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	31397			FBgn0011277
Human	4807	ENSG00000171786		MIM:162360
Mouse	18071	ENSMUSG00000051251	All phenotypic alleles (4):Targeted, knock-out(1) Targeted, other(3)	MGI:98481
Xenopus	100125788, 495280, 398086			989789
Zebrafish

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Links to other databases

Entrez Gene	373910
Ensembl Gene
KEGG	gga:373910

Entry 1

GEISHA Id	NHLH1.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	AACTTGCTGGGCTGAGGGTTTG
Reverse cDNA Template Primer	ATTAACCCTCACTAAAGGATGCGAAGAGGGCGTGTAAAGG	cDNA Template Length	801
Forward cDNA Template Probe	show TAGGGGTTNCACGCCTCACTCTGGCTCAGAGCTGAAGGGTAGTGCAGGGTGGGGATGCACAGCTCTGGGATGAGGTGCT CCCAGAGTGGGATGCATTGGGGAGGTGGGTGTGCAGTGAAGGGGCTCAGCCAGGCCCCAGGTGACAGCAGCTCCAGCCA GGCATAGGTCAGTATGGCCTTGGGCACCATGCAGCTGTCCATGGTGTAGTGTGGCCGGATCCTGCCCTACGTCTGCAGC ATGCTGAGTACTCTGTGCCACACCAGGATGGAGCTGGAGAGGCTTCTCTGTGCACAGGGGAGAGCGCTGGGAAGGTGGG GTGGTCCCCAGGCGGTGCCCTGTGGCTGGAGGGGCAGATGGATGGGACTGTGGGCTGCTTGGTGCCTCATGGGCACAGT CTGTGGCTTGTAGAAAAGAGGTGACATGGGTGAAGGTGGACCANGTCGTGGCTGTGGGGACAGATGGACAGATGTGGGC TCANGATCCCATTGGCACTATCANCGGGACATGCANCANAANGACANACANACNTTGGGAACANACNGGCTTCANGCAN CANGTCCANCANGACANACANACATCTGATGGGCTGAACANCCCNCCTGGCTCANGCANCACNNACANACANATGNATG TGNNCTTGNTGNTGNNNANATNCANTTTATNNATA

Stage

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Location (click to highlight)

Comments (click to highlight)

4-6

stage 5

Unlabeled

7-12

stage 8

stage 9

stage 12

Endoderm
Foregut
Hindbrain
Lateral Plate Mesoderm
Neural Crest
Neural Plate/Tube

13-18

stage 14

stage 17

Hindbrain
Midbrain
Neural Crest
Neural Plate/Tube
Oral Pharynx
Spinal Cord

19-24

stage 22

stage 24

Hindbrain
Midbrain
Nasal Placode/Nerve
Spinal Cord
Spinal Ganglia and Nerves

stage 25

Eye
Forebrain
Hindbrain
Midbrain
Nasal Placode/Nerve
Spinal Cord
Spinal Ganglia and Nerves

Entry 2

GEISHA Id	NHLH1.Ratie.2013	Data Source	Publication
Complete cDNA Template Probe	show CCTGCATGGTCCTTGAGCTCCTGCCCTATTCGTGGCATGCTCGGGCCCCAAGGATCCCGGGGCTCATCCCACCGAGCAG GTCGCCAACTTTCTGCCTCCTCCATGGACGGATGAGCAAGCAGTTCCCGGATTACTTTGGGCTTCAGGAAGAGGAAAGC TGGAGCCTGGGAATGGTCGTCAACTCAGGGTTTATTGCCGTCGCCCCTCCAGCAAGAAAAAGGGAAGCACTCTGAAGTC GTGCAGAGACGCCGTGTGATGAGGAGGAGGAGGAGAGCCAGTGGGGCAGTGCTGTGAGCAAGAGGCCCTGTCCCAGTGG ATTCGCTTCGCCTCACTCCACCCCCAGCCCAGCATCTGTCCATCTGTCCATCCATCCATCCGTCCATCCATCCGCACCC ACCATGCTCAACTCGGAGCAGACAGAGCTCGACCTCCCGCCCGCGCACTCCGAGCCCGAATCCGTCTTCAGCGACTGCG GCCGCGTGGGCGGCGCGGAGGAGTCCGGCGTCGCTTTGTGCCCTCAGCCCCGCGGGGCCGAGCAGGCAGAGGCGGTGAA GAAGGACCTGCAGCACCTGAGCCGGGAGGAGCGGCGGCGGCGGCGGCGAACCACGGCCAAGTACCGCACAGCCCACGCC ACGAGGGAACGCATCCGCGTGGAAGCCTTCAACATGGCCTTCGCCGAGCTGCGCAAGCTGCTGCCCACGCTGCCGCCCG ACAAGAAGCTCTCCAAGATTGAGATCCTTCGCCTGGCTATCTGCTACATCTCCTACCTGAACCACGTGCTGGATGTCTG AGCCGCCCAGCCTGTGTCTGTTTGTCTGTCCGTCCACCCGTCCGTCACCAACCCAACCAACTTGCTGGGCTGAGGGTTT GAGTATGTCTGGTCCAGATGCGACCCAACAATGCTGCACCTGTATCTGTCTGACTGCTTGGATGGACTGAATCCCATCT GCCTGCTCTGCCTCTATCCATAAACTGCATCTCCCCACCACCAAGCCCACATCCATCTGTCTGTCCGTGCTGCCTGAGC CAGGCGGGCTGTTCAGCCCATCAGATGTCTGTCTGTCCTGCTGGACCTGCTGCCTGAAGCCCGTCTGTTCCCAACGTCT GTCTGTCCTTCTGCTGCATGTCCCGCTGATAGTGCCAATGGGATCCTGAGCCCACATCTGTCCATCTGTCCCCACAGCC ACGACCTGGTCCACCTTCACCCATGTCACCTCTTTTCTACAAGCCACAGACTGTGCCCATGAGGCACCAAGCAGCCCAC AGTCCCATCCATCTGCCCCTCCAGCCACAGGGCACCGCCTGGGGACCACCCCACCTTCCCAGCGCTCTCCCCTGTGCAC AGAGAAGCCTCTCCAGCTCCATCCTGGTGTGGCACAGAGTACTCAGCATGCTGCAGACGTAGGGCAGGATCCGGCCACA CTACACCATGGACAGCTGCATGGTGCCCAAGGCCATACTGACCTATGCCTGGCTGGAGCTGCTGTCACCTGGGGCCTGG CTGAGCCCCTTCACTGCACACCCACCTCCCCAATGCATCCCACTCTGGGAGCACCTCATCCCAGAGCTGTGCATCCCCA CCTGCACTACCCTCAGCTCTGAGCAGAGTGAGCGTGGAACCCCTAGCCCTTTACACGCCCTCTTCGCATCAATATCCCT GACAGCCCCAGAGCAATCTTCATACCCCACCTCTTCCTCTGTCTCCCCTGTTACTTTCTAAGAGTTAATTTTGCACTGG CGGTGGCAGGAGCACGAGCAGAGCTCCATGGGGACCGGGACAGAGCAGAAAGTGCCTGCTGTGCCCAAAGGCAGTGTGC TGCTCACTGCAGGGTGGAATATGGCCCAACTCCATCCCCGTCCTGGCACTGCCCACAGCTCCAGACCCCATCTCCCTGC ATCCCCAGAGCAGCCCACATCCCATGGGACGTGCTCGGGGATGTGGCATCCCCAAGGGACACGGACAGAGCAGGGCAGC CCACCCGTCCCCTCCACTCAGCCCACGGCCCTGCGCCACGAGGATATTTATTTGAATTAATTTTATTGATAAATGTTAT TATTTATTTGCTGTGTTGTGCACTTTTCGGAAAAGAAACCTAGGAAGCAAACAACAAACAGAAACAACCACGGTGGAAA GCAGCCCAACCCACCCCTGTGTGCCCCAGCTTGCATTTCGTCTTGGCTGTTCGGACTGTGTGAGGATTTATTATTTATG AGTTCACGAGGAAGTCGGGGAGGGGGAAATGAATTAAACTGCCAGCAAAAGAGATCTTGAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAA
Citation	Leslie Ratié, Michelle Ware, Frédérique Barloy-Hubler, Hélène Romé, Isabelle Gicquel, Christèle Dubourg, Véronique David and Valérie Dupé. Novel genes upregulated when NOTCH signalling is disrupted during hypothalamic development. Neural Dev. 2013 Dec 23;8:25. doi: 10.1186/1749-8104-8-25.
Copyright	© 2013 Ratié et al.; licensee BioMed Central Ltd.
Comments	The sequence below was obtained from NCBI (acc # NM_204121.1) using the information provided in the publication as described in Ratie et al.

Stage

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13-15

stage 15

Hypothalamus
Midbrain

left embryo = control vehicle, DMSO; right embryo = DAPT-treated

Entry 3

GEISHA Id	NHLH1.Ware.2014	Data Source	Publication
Complete cDNA Template Probe	show CCTGCATGGTCCTTGAGCTCCTGCCCTATTCGTGGCATGCTCGGGCCCCAAGGATCCCGGGGCTCATCCCACCGAGCAG GTCGCCAACTTTCTGCCTCCTCCATGGACGGATGAGCAAGCAGTTCCCGGATTACTTTGGGCTTCAGGAAGAGGAAAGC TGGAGCCTGGGAATGGTCGTCAACTCAGGGTTTATTGCCGTCGCCCCTCCAGCAAGAAAAAGGGAAGCACTCTGAAGTC GTGCAGAGACGCCGTGTGATGAGGAGGAGGAGGAGAGCCAGTGGGGCAGTGCTGTGAGCAAGAGGCCCTGTCCCAGTGG ATTCGCTTCGCCTCACTCCACCCCCAGCCCAGCATCTGTCCATCTGTCCATCCATCCATCCGTCCATCCATCCGCACCC ACCATGCTCAACTCGGAGCAGACAGAGCTCGACCTCCCGCCCGCGCACTCCGAGCCCGAATCCGTCTTCAGCGACTGCG GCCGCGTGGGCGGCGCGGAGGAGTCCGGCGTCGCTTTGTGCCCTCAGCCCCGCGGGGCCGAGCAGGCAGAGGCGGTGAA GAAGGACCTGCAGCACCTGAGCCGGGAGGAGCGGCGGCGGCGGCGGCGAACCACGGCCAAGTACCGCACAGCCCACGCC ACGAGGGAACGCATCCGCGTGGAAGCCTTCAACATGGCCTTCGCCGAGCTGCGCAAGCTGCTGCCCACGCTGCCGCCCG ACAAGAAGCTCTCCAAGATTGAGATCCTTCGCCTGGCTATCTGCTACATCTCCTACCTGAACCACGTGCTGGATGTCTG AGCCGCCCAGCCTGTGTCTGTTTGTCTGTCCGTCCACCCGTCCGTCACCAACCCAACCAACTTGCTGGGCTGAGGGTTT GAGTATGTCTGGTCCAGATGCGACCCAACAATGCTGCACCTGTATCTGTCTGACTGCTTGGATGGACTGAATCCCATCT GCCTGCTCTGCCTCTATCCATAAACTGCATCTCCCCACCACCAAGCCCACATCCATCTGTCTGTCCGTGCTGCCTGAGC CAGGCGGGCTGTTCAGCCCATCAGATGTCTGTCTGTCCTGCTGGACCTGCTGCCTGAAGCCCGTCTGTTCCCAACGTCT GTCTGTCCTTCTGCTGCATGTCCCGCTGATAGTGCCAATGGGATCCTGAGCCCACATCTGTCCATCTGTCCCCACAGCC ACGACCTGGTCCACCTTCACCCATGTCACCTCTTTTCTACAAGCCACAGACTGTGCCCATGAGGCACCAAGCAGCCCAC AGTCCCATCCATCTGCCCCTCCAGCCACAGGGCACCGCCTGGGGACCACCCCACCTTCCCAGCGCTCTCCCCTGTGCAC AGAGAAGCCTCTCCAGCTCCATCCTGGTGTGGCACAGAGTACTCAGCATGCTGCAGACGTAGGGCAGGATCCGGCCACA CTACACCATGGACAGCTGCATGGTGCCCAAGGCCATACTGACCTATGCCTGGCTGGAGCTGCTGTCACCTGGGGCCTGG CTGAGCCCCTTCACTGCACACCCACCTCCCCAATGCATCCCACTCTGGGAGCACCTCATCCCAGAGCTGTGCATCCCCA CCTGCACTACCCTCAGCTCTGAGCAGAGTGAGCGTGGAACCCCTAGCCCTTTACACGCCCTCTTCGCATCAATATCCCT GACAGCCCCAGAGCAATCTTCATACCCCACCTCTTCCTCTGTCTCCCCTGTTACTTTCTAAGAGTTAATTTTGCACTGG CGGTGGCAGGAGCACGAGCAGAGCTCCATGGGGACCGGGACAGAGCAGAAAGTGCCTGCTGTGCCCAAAGGCAGTGTGC TGCTCACTGCAGGGTGGAATATGGCCCAACTCCATCCCCGTCCTGGCACTGCCCACAGCTCCAGACCCCATCTCCCTGC ATCCCCAGAGCAGCCCACATCCCATGGGACGTGCTCGGGGATGTGGCATCCCCAAGGGACACGGACAGAGCAGGGCAGC CCACCCGTCCCCTCCACTCAGCCCACGGCCCTGCGCCACGAGGATATTTATTTGAATTAATTTTATTGATAAATGTTAT TATTTATTTGCTGTGTTGTGCACTTTTCGGAAAAGAAACCTAGGAAGCAAACAACAAACAGAAACAACCACGGTGGAAA GCAGCCCAACCCACCCCTGTGTGCCCCAGCTTGCATTTCGTCTTGGCTGTTCGGACTGTGTGAGGATTTATTATTTATG AGTTCACGAGGAAGTCGGGGAGGGGGAAATGAATTAAACTGCCAGCAAAAGAGATCTTGAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAA
Citation	Ware M, Hamdi-Rozé H and Dupé V (2014) Notch signaling and proneural genes work together to control the neural building blocks for the initial scaffold in the hypothalamus. Front Neuroanat. 2014 Dec 2;8:140. doi: 10.3389/fnana.2014.00140.
Copyright	Copyright © 2014 Ware, Hamdi-Rozé and Dupé
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence was obtained from NCBI (Acc. # NM_204121.1).

Stage

Image (click image to view full size)

Location (click to highlight)

Comments (click to highlight)

7-11

stage 11

Hypothalamus

Entry 4

GEISHA Id	NHLH1.Ratie.2014	Data Source	Publication
Complete cDNA Template Probe	show CCTGCATGGTCCTTGAGCTCCTGCCCTATTCGTGGCATGCTCGGGCCCCAAGGATCCCGGGGCTCATCCCACCGAGCAG GTCGCCAACTTTCTGCCTCCTCCATGGACGGATGAGCAAGCAGTTCCCGGATTACTTTGGGCTTCAGGAAGAGGAAAGC TGGAGCCTGGGAATGGTCGTCAACTCAGGGTTTATTGCCGTCGCCCCTCCAGCAAGAAAAAGGGAAGCACTCTGAAGTC GTGCAGAGACGCCGTGTGATGAGGAGGAGGAGGAGAGCCAGTGGGGCAGTGCTGTGAGCAAGAGGCCCTGTCCCAGTGG ATTCGCTTCGCCTCACTCCACCCCCAGCCCAGCATCTGTCCATCTGTCCATCCATCCATCCGTCCATCCATCCGCACCC ACCATGCTCAACTCGGAGCAGACAGAGCTCGACCTCCCGCCCGCGCACTCCGAGCCCGAATCCGTCTTCAGCGACTGCG GCCGCGTGGGCGGCGCGGAGGAGTCCGGCGTCGCTTTGTGCCCTCAGCCCCGCGGGGCCGAGCAGGCAGAGGCGGTGAA GAAGGACCTGCAGCACCTGAGCCGGGAGGAGCGGCGGCGGCGGCGGCGAACCACGGCCAAGTACCGCACAGCCCACGCC ACGAGGGAACGCATCCGCGTGGAAGCCTTCAACATGGCCTTCGCCGAGCTGCGCAAGCTGCTGCCCACGCTGCCGCCCG ACAAGAAGCTCTCCAAGATTGAGATCCTTCGCCTGGCTATCTGCTACATCTCCTACCTGAACCACGTGCTGGATGTCTG AGCCGCCCAGCCTGTGTCTGTTTGTCTGTCCGTCCACCCGTCCGTCACCAACCCAACCAACTTGCTGGGCTGAGGGTTT GAGTATGTCTGGTCCAGATGCGACCCAACAATGCTGCACCTGTATCTGTCTGACTGCTTGGATGGACTGAATCCCATCT GCCTGCTCTGCCTCTATCCATAAACTGCATCTCCCCACCACCAAGCCCACATCCATCTGTCTGTCCGTGCTGCCTGAGC CAGGCGGGCTGTTCAGCCCATCAGATGTCTGTCTGTCCTGCTGGACCTGCTGCCTGAAGCCCGTCTGTTCCCAACGTCT GTCTGTCCTTCTGCTGCATGTCCCGCTGATAGTGCCAATGGGATCCTGAGCCCACATCTGTCCATCTGTCCCCACAGCC ACGACCTGGTCCACCTTCACCCATGTCACCTCTTTTCTACAAGCCACAGACTGTGCCCATGAGGCACCAAGCAGCCCAC AGTCCCATCCATCTGCCCCTCCAGCCACAGGGCACCGCCTGGGGACCACCCCACCTTCCCAGCGCTCTCCCCTGTGCAC AGAGAAGCCTCTCCAGCTCCATCCTGGTGTGGCACAGAGTACTCAGCATGCTGCAGACGTAGGGCAGGATCCGGCCACA CTACACCATGGACAGCTGCATGGTGCCCAAGGCCATACTGACCTATGCCTGGCTGGAGCTGCTGTCACCTGGGGCCTGG CTGAGCCCCTTCACTGCACACCCACCTCCCCAATGCATCCCACTCTGGGAGCACCTCATCCCAGAGCTGTGCATCCCCA CCTGCACTACCCTCAGCTCTGAGCAGAGTGAGCGTGGAACCCCTAGCCCTTTACACGCCCTCTTCGCATCAATATCCCT GACAGCCCCAGAGCAATCTTCATACCCCACCTCTTCCTCTGTCTCCCCTGTTACTTTCTAAGAGTTAATTTTGCACTGG CGGTGGCAGGAGCACGAGCAGAGCTCCATGGGGACCGGGACAGAGCAGAAAGTGCCTGCTGTGCCCAAAGGCAGTGTGC TGCTCACTGCAGGGTGGAATATGGCCCAACTCCATCCCCGTCCTGGCACTGCCCACAGCTCCAGACCCCATCTCCCTGC ATCCCCAGAGCAGCCCACATCCCATGGGACGTGCTCGGGGATGTGGCATCCCCAAGGGACACGGACAGAGCAGGGCAGC CCACCCGTCCCCTCCACTCAGCCCACGGCCCTGCGCCACGAGGATATTTATTTGAATTAATTTTATTGATAAATGTTAT TATTTATTTGCTGTGTTGTGCACTTTTCGGAAAAGAAACCTAGGAAGCAAACAACAAACAGAAACAACCACGGTGGAAA GCAGCCCAACCCACCCCTGTGTGCCCCAGCTTGCATTTCGTCTTGGCTGTTCGGACTGTGTGAGGATTTATTATTTATG AGTTCACGAGGAAGTCGGGGAGGGGGAAATGAATTAAACTGCCAGCAAAAGAGATCTTGAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAA
Citation	Ratié L, Ware M, Jagline H, David V and Dupé V (2014) Dynamic expression of Notch-dependent neurogenic markers in the chick embryonic nervous system. Front. Neuroanat. 8:158. doi: 10.3389/fnana.2014.00158
Copyright	Copyright © 2014 Ratié, Ware, Jagline, David and Dupé.
Comments	The sequence below was obtained from NCBI (acc # NM_204121.1) using the information provided in the publication as described in Ratie et al.