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OLIG2 Gene Summary Expression Transcript Levels Other Species Expression JBrowse Gene Official Symbol OLIG2 Official Full Name oligodendrocyte transcription factor 2 CGNC ID 10371 also known as oligodendrocyte transcription factor 2|bHLH protein OLIG2|bHLH transcription factor Olig2|oligo2|oligodendrocyte lineage transcription factor 2, OLIG2, Oligodendrocyte transcription factor 3 , Oligo3, Class B basic helix- loop-helix protein 7, bHLHB7 gene type protein-coding
Genomic Map Sequence Information Gene Expression Orthology Gene Ontology Molecular Function DNA binding , HMG box domain binding , protein homodimerization activity , more... RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity Biological Process myelination , negative regulation of neuron differentiation , more... negative regulation of transcription from RNA polymerase II promoter , neuron fate commitment , positive regulation of oligodendrocyte differentiation , spinal cord motor neuron differentiation , spinal cord oligodendrocyte cell fate specification , thalamus development Cellular Component cytoplasm , nucleus
Links to other databases
Entry 1 GEISHA Id Olig2.Gimeno.2007 Data Source Publication Complete cDNA Template Probe show CCCGACACGGCGCGCCGCTGCCCACGGCCGCCCCGAGCACGGCAGCCCGCCCGCCGGGCCATGGACTCGGACGCCAGCC
Citation Gimeno L, Martinez S. Expression of chick Fgf19 and mouse Fgf15 orthologs is regulated in the developing brain by Fgf8 and Shh. Dev Dyn. 2007 Aug;236(8):2285-97. Copyright Copyright © 2007 Wiley-Liss, Inc. Comments OLIG2 has been renamed OLIG3. Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_001031526.1).
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-20
stage 20
Forebrain Midbrain
Entry 2 GEISHA Id Olig2.Politis.2007 Data Source Publication Complete cDNA Template Probe show CCCGACACGGCGCGCCGCTGCCCACGGCCGCCCCGAGCACGGCAGCCCGCCCGCCGGGCCATGGACTCGGACGCCAGCC
Citation Politis PK, Rohrer H, Matsas R (2007). Expression pattern of BM88 in the developing nervous system of the chick and mouse embryo. Gene Expr Patterns. 2007 Jan;7(1-2):165-77. Epub 2006 Jul 4 Copyright Reprinted with permission from Elsevier.
Copyright © 2006 Elsevier B.V. All rights reserved. Comments According to authors , "The following probes were used: cSCG10, cNotch1, cOlig2 (kindly provided by Masato Nakafuku), cNkx6.1 (kindly provided by James Briscoe) and Mash1 (kindly provided by Francois Guillemot). As information provided was insufficient to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #AF411041)
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-24 stage 24
stage 24
Spinal Cord 25-30 stage 29
Spinal Cord 31-33 stage 33
Spinal Cord
Entry 3 GEISHA Id OLIG2.GarciaCampmany.2007 Data Source Publication Complete cDNA Template Probe show CCCGACACGGCGCGCCGCTGCCCACGGCCGCCCCGAGCACGGCAGCCCGCCCGCCGGGCCATGGACTCGGACGCCAGCC
Citation García-Campmany L, Martí E. The TGFbeta intracellular effector Smad3 regulates neuronal differentiation and cell fate specification in the developing spinal cord. Development. 2007 Jan;134(1):65-75. Epub 2006 Nov 30. Copyright Copyright by the authors. Published by the Company of Biologists Ltd. Comments As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_001031526.1
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 7-12 stage 12
stage 12
Spinal Cord 19-20 stage 20
stage 20
Spinal Cord
Entry 4 GEISHA Id Olig2.Zhou.2001 Data Source Publication Complete cDNA Template Probe show CCCGACACGGCGCGCCGCTGCCCACGGCCGCCCCGAGCACGGCAGCCCGCCCGCCGGGCCATGGACTCGGACGCCAGCC
Citation Zhou Q, Choi G, Anderson DJ. The bHLH transcription factor Olig2 promotes oligodendrocyte differentiation in collaboration with Nkx2.2. Neuron. 2001 Sep 13;31(5):791-807 Copyright Copyright 2001 by Cell Press Comments The sequence below was obtained from NCBI (acc # AF411041) using the information provided in the publication as described in Zhou.2001 et al.
Stage Image (click image to view full size) Location (click to highlight) Comments (click to highlight) 19-24 stage 19
stage 23
Spinal Cord 25-30 stage 26
stage 29
Spinal Cord 31-36 stage 31
stage 31
stage 34
stage 36
Spinal Cord
Data from NCBI Unigene EST ProfileGga.51492
Mouse Frog Fruit Fly Zebra Finch Zebrafish
