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A chicken embryo gene expression database

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TUBB1
tubulin beta 1 class VI

The human orthologue of this gene is associated
with the following human disease:

Macrothrombocytopenia, autosomal dominant, TUBB1-related

Gene

Official Symbol	TUBB1
Official Full Name	tubulin beta 1 class VI
CGNC ID	49797
also known as	tubulin beta-6 chain\|beta-tubulin class-VI\|tubulin, beta 3, Tubulin beta-6 chain , Beta-tubulin class-VI
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_205445
Polypeptide	NP_990776
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.819

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	81027	ENSG00000101162	MIM:613112	MIM:612901
Mouse	545486		All phenotypic alleles (3):Targeted, knock-out(1) Targeted, other(2)	MGI:107814
Xenopus
Zebrafish	558552	ENSDARG00000053066	ZDB-GENE-110408-5	ZFIN:ZDB-GENE-110408-5

Gene Ontology

Molecular Function	GTPase activity, GTP binding, structural constituent of cytoskeleton
Biological Process	protein polymerization, spindle assembly
Cellular Component	cytoplasm, microtubule, plasma membrane

Links to other databases

Entrez Gene	396427
Ensembl Gene	ENSGALG00000007447
KEGG	gga:396427

GEISHA Id	TUBB1.Agarwala.2005	Data Source	Publication
Complete cDNA Template Probe	show GCTTCTCCTAGAGAACTGCAGCTGGAAAGCCTGCGCTAGGTTGTAGCTACCAACAGTTAAGCTACACAAAATGCGTGAG ATCGTGCACCTTCAGATTGGCCAGTGTGGAAACCAAATTGGAGCTAAGTTCTGGGAGGTGATAAGTGATGAACATGGAA TTGATATTGCCGGAAACTACTGTGGGAATGCATCGCTGCAGCTTGAGCGAATTAACGTGTACTTCAATGAGGCTTATTC CCATAAATATGTGCCCCGTTCTATCTTGGTGGACCTGGAGCCTGGTACAATGGACAGTGTACGATCTAGCAAAATAGGC CCACTGTTTCGACCTGACAATTTTATTCATGGTAATTCAGGTGCTGGAAACAACTGGGCTAAGGGCCATTACACAGAAG GAGCTGAGCTGATTGAAAATGTCATGGATGTGGTCAGGAACGAGTGTGAGAGCTGTGACTGCCTGCAGGGATTCCAGCT CATCCATTCGCTTGGTGGTGGTACAGGCTCAGGTATGGGCACACTCCTCATCAACAAAATCAGGGAAGAATATCCCGAC AGAATTATGAACACTTTCAGCGTTGTTCCTTCACCCAAAGTATCTGACACAGTTGTAGAGCCCTATAATGCCATCCTCT CCATCCATCAGCTAATAGAGAATACAGATGAAACCTTTTGCATCGACAACGAAGCACTATATGATATATGTTTTAGAAC TTTAAAGCTCACCAATCCCACCTATGGTGACCTCAATCACTTAGTGTCCCTAACAATGAGCGGTGTTACAACCTCACTC CGTTTTCCTGGTCAGCTGAATGCAGATCTGAGGAAGCTGGCTGTTAACATGGTGCCCTTTCCTCGCCTGCATTTCTTTA TGCCAGGCTTTGCTCCGCTAACAGCGCGAGGTAGCCAGCAGTACAGAGCCCTCTCAGTGCCAGAGCTTACTCAACAGAT GTTTGATGCACGCAACATGATGGCAGCCTGCGACCCCCGTCGTGGGCGTTATTTGACTGTGGCGTGCATCTTCAGAGGC CGGATGTCTACCAGAGAAGTGGATGAACAGTTGCTGTCTGTCCAGACCAAGAACAGCTCCTACTTTGTGGAGTGGATCC CTAACAATGTCAAAGTGGCTGTGTGTGACATACCACCGCGAGGACTGAAGATGGCAGCTACCTTTATTGGCAATAACAC AGCCATTCAGGAACTCTTCATCAGGGTTTCTGAACAGTTTTCAGCTATGTTCAGAAGAAAAGCGTTTCTCCATTGGTAC ACTGGTGAAGGCATGGATGAGATGGAGTTTTCCGAAGCAGAGGGAAACACCAATGACCTTGTTTCTGAGTATCAGCAGT ACCAAGATGCCACTGCAGATGTTGAGGAATATGAAGAAGCGGAAGCTAGCCCAGAAAAAGAAACATAGAAACAATGGAG GTATAAAACATTCTCCAAGTAAGCCTGTTGTCATTCACTAAAGGAAAAACATTAGCCACAAGCTGCATACCAAAAATAA CACCTTCCTTAAGATTATTTTCCTCTCCAAAATTACAGTACTGTGCTTTTGAAATTAACAGCAGGTATGGTCTACTTTC CTCTCTACACTAAATGACTCCCAGAAAGGATCCACTATGAAGACAGGTTCCCTCATAACCGTCTTCTAAATGTATTCCC TTGTGGAATACTATTGCTAGACGCTGCATGTAATATGCAGACAGTGTGTGTGTGTATTAGGGTCACAAGCAACAGCAAA AGATGTTATAAACTCATCAAATTTACTTATTTTCAGGTAACCAAAGTCCATGTTTTGTCTGTGAACTTGCTACTGCGTT GGGAACACACATTTGTAAGGCCTATAAAGGCAATATGTCGTCATGCACTCTAGAGATGGATCTAGAGCTGTCAACAATT TCAGTTCCTTTAGCAGCAGAATGAAGGGGAAAAACAAAAGACTAAATATTCTTTTTTTTTTCTTTTAAGAGGTTCTATT TTAATAGTCCTGTCACATTGCTGGTTTGCATTATTGCAGAGCTTGTACTCATTTAGTGGTTTATTTCAATTTCAAACTA TAGCTTCAGTTATACTAGCATACCAAATTGCAAACAGTGTTTAACAGTTTTGGTGTGGTGTTTTGGTTTTTGTTTCCCT CCTTCTATGTAGTAACTATTATAAATTTTCTTCCTATCACTCAGTACAGCAACAGATGGAATGGTTTGCAGCTAAATAA GAGATGTAAGTTCAAGGGCAATCACTAAATAAGAAAAATACCTTGAGGAAGAAAAATATGCCTTTCACAGCCATCTAAT TAACATTGCATTTATAATATTCCTTGAAATAAAAATATATAGCATTCTGTAAAATACTTCAACACTTGAAAAATGTAGT AGGCAAAAATCATAGTTTGTAACGACTAACATGCACTTAAAAATTGTTACTTGAAAAAAAAAAAAAAGCTTGTTTTACT CAGGAGAGATTCTGTTGTACTCTAATGAAAGGCCACACCTCATGTTTTAGTCTTCTGTATTGTAGTCAGCAGTAGAAGC ATCCAGGTAAACACATCTGAATCCAGCTATGGAAGTACATTATCTTCCTTCCTATGCACAGGGACAATATTATACTTGC TGCTGAGATACACAGCAGCAGAAACATCCATCTTCACTTGGTTAGGGGAAATGACTGTGTTCCCCTCCGTTCCCACTGC TTCCTAGTGAATCCATGCCTGCTCCCTCACAGGGAAAGTGACAAAGTGCCAACAGGGACAGTAATACAGTCCAGAGCCT TCTGCACTTCCCTTCCCACCCCATACAGGGAGCCACCTCCAACTCCTGATTCCACTGATCATGGTCCAGACAGTCTTGG AGATGGATCAAATGCAACACCTCCATGGAGAAGTATTCTACTTTGTTTTCCCTTAAACCTAAGTGACACCAAAATGCCT TTGGCTGAAAAAATTTATTCTGAGCACAAAAGCATTCATTATGGAAATGAAGCAGGCAAAAAAGTTTTAAACAGCAGTT ACATCTCTCTCTTATTTATAGACCTGAAATATCAGCATGAAAGCCAAGAAGAGATCTGTCTTGACAATAAACATCTGTT GC
Citation	Agarwala S, Aglyamova GV, Marma AK, Fallon JF, Ragsdale CW. Differential susceptibility of midbrain and spinal cord patterning to floor plate defects in the talpid2 mutant. Dev Biol. 2005 Dec 1;288(1):206-20. Epub 2005 Oct 21.
Copyright	Copyright © 2005 Elsevier Inc. All rights reserved.
Comments	According to the authors, "Digoxigenin (DIG)- and fluorescein-labeled riboprobes were synthesized from chick cDNA plasmids..." As information provided was insufficient to verify exact sequence used to synthesize probe,the sequence below was obtained from NCBI (NM_205445).