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SRC
SRC proto-oncogene, non-receptor tyrosine kinase| Gene | | Official Symbol | SRC | | Official Full Name | SRC proto-oncogene, non-receptor tyrosine kinase | | CGNC ID | | | also known as | PP60C-SCR, SDR, c-src, proto-oncogene tyrosine-protein kinase Src|c-src protein, C terminus|non-tyrosine protein kinase|p60-Src|pp60c-src|proto-oncogene c-Src|v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog|v-src sarcoma viral oncogene | | gene type | protein-coding |
| | Genomic Map | | | Sequence Information | | | Gene Expression | | | Orthology | | | Gene Ontology | | Molecular Function | ATP binding, ephrin receptor binding, heme binding, identical protein binding, ion channel binding, more...non-membrane spanning protein tyrosine kinase activity, phosphoprotein binding, protein binding, protein phosphatase binding, SH2 domain binding | | Biological Process | bone resorption, branching involved in mammary gland duct morphogenesis, cell adhesion, cell cycle, more...cell migration, forebrain development, immune system process, negative regulation of anoikis, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of extrinsic apoptotic signaling pathway, negative regulation of intrinsic apoptotic signaling pathway, negative regulation of protein homooligomerization, oogenesis, positive regulation of canonical Wnt signaling pathway, positive regulation of ERK1 and ERK2 cascade, positive regulation of podosome assembly, positive regulation of protein kinase B signaling, protein autophosphorylation, regulation of intracellular estrogen receptor signaling pathway, regulation of protein binding, response to interleukin-1, uterus development | | Cellular Component | caveola, cytoskeleton, endosome membrane, late endosome, lysosome, mitochondrial inner membrane, nucleus |
| | Links to other databases | |
| GEISHA Id | SRC.Kao.2009 | Data Source | Publication | | Complete cDNA Template Probe | show CAGCCCACCACCATGGGGAGCAGCAAGAGCAAGCCCAAGGACCCCAGCCAGCGCCGGCGCAGCCTGGAGCCACCCGACA
GCACCCACCACGGGGGATTCCCAGCCTCGCAGACCCCCAACAAGACAGCAGCCCCCGACACGCACCGCACCCCCAGCCG
CTCCTTTGGGACCGTGGCCACCGAGCCCAAGCTCTTCGGGGGCTTCAACACTTCTGACACCGTCACGTCGCCTCAGCGT
GCCGGGGCACTGGCTGGCGGCGTCACCACTTTCGTGGCTCTCTACGACTACGAGTCCCGGACTGAAACGGACTTGTCCT
TCAAGAAAGGAGAACGCCTGCAGATTGTCAACAACACGGAAGGTGACTGGTGGCTGGCTCATTCCCTCACTACAGGACA
GACGGGCTACATCCCCAGTAACTATGTCGCGCCCTCAGACTCCATCCAGGCTGAAGAGTGGTACTTTGGGAAGATCACT
CGTCGGGAGTCCGAGCGGCTGCTGCTCAACCCCGAAAACCCCCGGGGAACCTTCTTGGTCCGGGAGAGCGAGACGACAA
AAGGTGCCTATTGCCTCTCCGTTTCTGACTTTGACAACGCCAAGGGGCTCAATGTGAAGCACTACAAGATCCGCAAGCT
GGACAGCGGCGGCTTCTACATCACCTCACGCACACAGTTCAGCAGCCTGCAGCAGCTGGTGGCCTACTACTCCAAACAC
GCTGATGGCTTGTGCCACCGCCTGACCAACGTCTGCCCCACGTCCAAGCCCCAGACCCAGGGACTCGCCAAGGACGCGT
GGGAAATCCCCCGGGAGTCGCTGCGGCTGGAGGTGAAGCTGGGGCAGGGCTGCTTTGGAGAGGTCTGGATGGGGACCTG
GAACGGCACCACCAGAGTGGCCATAAAGACTCTGAAGCCCGGCACCATGTCCCCGGAGGCCTTCCTGCAGGAAGCCCAA
GTGATGAAGAAGCTCCGGCATGAGAAGCTGGTTCAGCTGTACGCAGTGGTGTCGGAAGAGCCCATCTACATCGTCACTG
AGTACATGAGCAAGGGGAGCCTCCTGGATTTCCTGAAGGGAGAGATGGGCAAGTACCTGCGGCTGCCACAGCTCGTCGA
TATGGCTGCTCAGATTGCATCCGGCATGGCCTATGTGGAGAGGATGAACTACGTGCACCGAGACCTGCGGGCGGCCAAC
ATCCTGGTGGGGGAGAACCTGGTGTGCAAGGTGGCTGACTTTGGGCTGGCACGCCTCATCGAGGACAACGAGTACACAG
CACGGCAAGGTGCCAAGTTCCCCATCAAGTGGACAGCCCCCGAGGCAGCCCTCTATGGCCGGTTCACCATCAAGTCGGA
TGTCTGGTCCTTCGGCATCCTGCTGACTGAGCTGACCACCAAGGGCCGGGTGCCATACCCAGGGATGGTCAACAGGGAG
GTGCTGGACCAGGTGGAGAGGGGCTACCGCATGCCCTGCCCGCCCGAGTGCCCCGAGTCGCTGCATGACCTCATGTGCC
AGTGCTGGCGGAAGGACCCTGAGGAGCGGCCCACTTTTGAGTACCTGCAGGCCTTCCTGGAGGACTACTTCACCTCGAC
AGAGCCCCAGTACCAGCCTGGAGAGAACCTATAGGCCTGGAGCTCCTCCTGGCACCAGAGGCCTCACTGTGGGGCACAG
GGGCCTGGCTCCGTGCAGAGGGGCCACGTTTTGGGGAGCAGCCCCAGAGCAGGATGTGGCATGGTGAGGTGTCGGGTGC
TCCATCGCTCATTAAAACTGTGCTGGGCCACCCTTAATGAGGTGGCGAGAGGAGCCCCGGGCACTGCCACCAGCGGAGC
TGGGGCTCAGGATGGCAAATGGAGCAGCAGGACGGCTCCTGGCACAGCCACGGCTTTCAGGACCCTCTTCTCACAGCAG
CCAGAGAAATTGGGGGACAACCCCTCCCACCTCAGACACACTGCCCCACACCTCCTGCACCCCCTTTTTTAAATCAGCA
CAAATTTCTTCACCCATTCACCCCCCCACTTCGCTCTGGTCTGCCCGAGGCCGTTTGCAGAGACGTTTGGCGATGCGGA
AGGCACTGCTTTGGATCGGATGCAGCTGGAGAGCAGACCTTGGGATGCCCCATGGAGGCTGATGGTCTCCCTTCCTCCG
GCACCCGCCCGTCCTCGGGCGCAGGGCTCAGTGTTTTAGGGAACTACTTGTCTTTCAGCGCTGCTTTTGTCCACCGGAG
TGTTTCTAGCCACCATCCCCCCCGCTTCTGCCATCCCCTTATCAGGGAGCACGGAGCCACCGCGAGCCGTTTGCAGGCC
CAGCTGCTCCCTGCTTGTGTGTTGGAGGTCGGAGTGATCCATGCACAGCCCGGTGCCCGCAGCAGCTCCCATTGAGCAC
CCCTGTACATAGTCCTCCAGCACCTCCCGCTACCTGACCAAGCTGCATGTGCTGTCGTGTTCCTCCTGTGGTACCGCCG
CCATCTGTCCTTGTTTGTCCCCAGCTGGAGCCCCGCATCACACCATCCCCACCTGTGTCCTGGACCTCTTATCCATCAC
TCACACCCGGTGCCAAAAACACCTCCGGAGAACCAGGCTGAGCCGCTGCTGCCTCCCGCTCGCTCCCCGGCGCCTTATT
TATTACCTGAGTTCTCCGTCGGTGGCTCCGCTCTAATAGTGAACTCAGTAGGAAGGGGCTGTCAGCAGTATGGAGGGAT
CCCACCTTTGCCCTGGAGGACTGTTTCCGTGCACTTCCGTACTCACGATGGGACTCAGAGCCCTTCGTCCCCCGGCACG
TTTCCTGTGCCCCCCTTGGTGCAGGGCCTGCCGCACCGCTGCGCTCACGGCCTTTTAAGCTCCGTCTCCGTGCCGTTTG
TGTGCCATCGCCACGCAGCGCGCACAGTGCCTGCATCCCCAGGGGGTGGGCAGTATCAGATGTGTAGCCGAGAGCT | | Citation | Kao TJ, Palmesino E, Kania A. SRC family kinases are required for limb trajectory selection by spinal motor axons. J Neurosci. 2009 Apr 29;29(17):5690-700. | | Copyright | Copyright © 2009-12 by the Society for Neuroscience | | Comments | Authors indicated the primer for SRC: 5′-TCATAGCCGAATAGCCTCTCCAC-3′.
Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc #NM_205457.2) |
| Stage | Image (click image to view full size) | Location (click to highlight) | Comments (click to highlight) | | 25-26 |
 | | stage 26 |
 | | stage 26 |
| Spinal Cord
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| | Data from NCBI Unigene EST Profile
Unigene ID: Gga.51508 |
MouseFrogFruit FlyZebra FinchZebrafish |
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