GEISHA - A Chicken Embryo Gene Expression Database
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SRC
SRC proto-oncogene, non-receptor tyrosine kinase

Gene
Official SymbolSRC
Official Full NameSRC proto-oncogene, non-receptor tyrosine kinase
CGNC ID
also known asPP60C-SCR, SDR, c-src, proto-oncogene tyrosine-protein kinase Src|c-src protein, C terminus|non-tyrosine protein kinase|p60-Src|pp60c-src|proto-oncogene c-Src|v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog|v-src sarcoma viral oncogene
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Sequence Information
Genomic
RNANM_205457
PolypeptideNP_990788
Gene Expression
In Situ HybridizationGEISHA
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly48973FBgn0262733
Human6714ENSG00000197122MIM:190090MIM:190090
Mouse20779ENSMUSG00000027646All phenotypic alleles (5):Targeted, knock-out(1) Targeted, other(4) MGI:98397
Xenopus496893, 380430, 373647489819
Zebrafish325084ENSDARG00000008107ZDB-GENE-030131-3809ZFIN:ZDB-GENE-030131-3809
Gene Ontology
Molecular FunctionATP binding, SH2 domain binding, ephrin receptor binding, heme binding, identical protein binding, more...ion channel binding, non-membrane spanning protein tyrosine kinase activity, phosphoprotein binding, protein binding, protein phosphatase binding
Biological Processbone resorption, branching involved in mammary gland duct morphogenesis, cell adhesion, cell cycle, more...cell migration, forebrain development, immune system process, negative regulation of anoikis, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of extrinsic apoptotic signaling pathway, negative regulation of intrinsic apoptotic signaling pathway, negative regulation of protein homooligomerization, oogenesis, positive regulation of ERK1 and ERK2 cascade, positive regulation of canonical Wnt signaling pathway, positive regulation of podosome assembly, positive regulation of protein kinase B signaling, protein autophosphorylation, regulation of intracellular estrogen receptor signaling pathway, regulation of protein binding, response to interleukin-1, uterus development
Cellular Componentcaveola, cytoskeleton, endosome membrane, late endosome, lysosome, mitochondrial inner membrane, nucleus
Links to other databases
Entrez Gene396442
Ensembl GeneENSGALG00000003855
KEGGgga:396442
GEISHA IdSRC.Kao.2009Data SourcePublication
Complete cDNA Template Probeshow
CAGCCCACCACCATGGGGAGCAGCAAGAGCAAGCCCAAGGACCCCAGCCAGCGCCGGCGCAGCCTGGAGCCACCCGACA
GCACCCACCACGGGGGATTCCCAGCCTCGCAGACCCCCAACAAGACAGCAGCCCCCGACACGCACCGCACCCCCAGCCG
CTCCTTTGGGACCGTGGCCACCGAGCCCAAGCTCTTCGGGGGCTTCAACACTTCTGACACCGTCACGTCGCCTCAGCGT
GCCGGGGCACTGGCTGGCGGCGTCACCACTTTCGTGGCTCTCTACGACTACGAGTCCCGGACTGAAACGGACTTGTCCT
TCAAGAAAGGAGAACGCCTGCAGATTGTCAACAACACGGAAGGTGACTGGTGGCTGGCTCATTCCCTCACTACAGGACA
GACGGGCTACATCCCCAGTAACTATGTCGCGCCCTCAGACTCCATCCAGGCTGAAGAGTGGTACTTTGGGAAGATCACT
CGTCGGGAGTCCGAGCGGCTGCTGCTCAACCCCGAAAACCCCCGGGGAACCTTCTTGGTCCGGGAGAGCGAGACGACAA
AAGGTGCCTATTGCCTCTCCGTTTCTGACTTTGACAACGCCAAGGGGCTCAATGTGAAGCACTACAAGATCCGCAAGCT
GGACAGCGGCGGCTTCTACATCACCTCACGCACACAGTTCAGCAGCCTGCAGCAGCTGGTGGCCTACTACTCCAAACAC
GCTGATGGCTTGTGCCACCGCCTGACCAACGTCTGCCCCACGTCCAAGCCCCAGACCCAGGGACTCGCCAAGGACGCGT
GGGAAATCCCCCGGGAGTCGCTGCGGCTGGAGGTGAAGCTGGGGCAGGGCTGCTTTGGAGAGGTCTGGATGGGGACCTG
GAACGGCACCACCAGAGTGGCCATAAAGACTCTGAAGCCCGGCACCATGTCCCCGGAGGCCTTCCTGCAGGAAGCCCAA
GTGATGAAGAAGCTCCGGCATGAGAAGCTGGTTCAGCTGTACGCAGTGGTGTCGGAAGAGCCCATCTACATCGTCACTG
AGTACATGAGCAAGGGGAGCCTCCTGGATTTCCTGAAGGGAGAGATGGGCAAGTACCTGCGGCTGCCACAGCTCGTCGA
TATGGCTGCTCAGATTGCATCCGGCATGGCCTATGTGGAGAGGATGAACTACGTGCACCGAGACCTGCGGGCGGCCAAC
ATCCTGGTGGGGGAGAACCTGGTGTGCAAGGTGGCTGACTTTGGGCTGGCACGCCTCATCGAGGACAACGAGTACACAG
CACGGCAAGGTGCCAAGTTCCCCATCAAGTGGACAGCCCCCGAGGCAGCCCTCTATGGCCGGTTCACCATCAAGTCGGA
TGTCTGGTCCTTCGGCATCCTGCTGACTGAGCTGACCACCAAGGGCCGGGTGCCATACCCAGGGATGGTCAACAGGGAG
GTGCTGGACCAGGTGGAGAGGGGCTACCGCATGCCCTGCCCGCCCGAGTGCCCCGAGTCGCTGCATGACCTCATGTGCC
AGTGCTGGCGGAAGGACCCTGAGGAGCGGCCCACTTTTGAGTACCTGCAGGCCTTCCTGGAGGACTACTTCACCTCGAC
AGAGCCCCAGTACCAGCCTGGAGAGAACCTATAGGCCTGGAGCTCCTCCTGGCACCAGAGGCCTCACTGTGGGGCACAG
GGGCCTGGCTCCGTGCAGAGGGGCCACGTTTTGGGGAGCAGCCCCAGAGCAGGATGTGGCATGGTGAGGTGTCGGGTGC
TCCATCGCTCATTAAAACTGTGCTGGGCCACCCTTAATGAGGTGGCGAGAGGAGCCCCGGGCACTGCCACCAGCGGAGC
TGGGGCTCAGGATGGCAAATGGAGCAGCAGGACGGCTCCTGGCACAGCCACGGCTTTCAGGACCCTCTTCTCACAGCAG
CCAGAGAAATTGGGGGACAACCCCTCCCACCTCAGACACACTGCCCCACACCTCCTGCACCCCCTTTTTTAAATCAGCA
CAAATTTCTTCACCCATTCACCCCCCCACTTCGCTCTGGTCTGCCCGAGGCCGTTTGCAGAGACGTTTGGCGATGCGGA
AGGCACTGCTTTGGATCGGATGCAGCTGGAGAGCAGACCTTGGGATGCCCCATGGAGGCTGATGGTCTCCCTTCCTCCG
GCACCCGCCCGTCCTCGGGCGCAGGGCTCAGTGTTTTAGGGAACTACTTGTCTTTCAGCGCTGCTTTTGTCCACCGGAG
TGTTTCTAGCCACCATCCCCCCCGCTTCTGCCATCCCCTTATCAGGGAGCACGGAGCCACCGCGAGCCGTTTGCAGGCC
CAGCTGCTCCCTGCTTGTGTGTTGGAGGTCGGAGTGATCCATGCACAGCCCGGTGCCCGCAGCAGCTCCCATTGAGCAC
CCCTGTACATAGTCCTCCAGCACCTCCCGCTACCTGACCAAGCTGCATGTGCTGTCGTGTTCCTCCTGTGGTACCGCCG
CCATCTGTCCTTGTTTGTCCCCAGCTGGAGCCCCGCATCACACCATCCCCACCTGTGTCCTGGACCTCTTATCCATCAC
TCACACCCGGTGCCAAAAACACCTCCGGAGAACCAGGCTGAGCCGCTGCTGCCTCCCGCTCGCTCCCCGGCGCCTTATT
TATTACCTGAGTTCTCCGTCGGTGGCTCCGCTCTAATAGTGAACTCAGTAGGAAGGGGCTGTCAGCAGTATGGAGGGAT
CCCACCTTTGCCCTGGAGGACTGTTTCCGTGCACTTCCGTACTCACGATGGGACTCAGAGCCCTTCGTCCCCCGGCACG
TTTCCTGTGCCCCCCTTGGTGCAGGGCCTGCCGCACCGCTGCGCTCACGGCCTTTTAAGCTCCGTCTCCGTGCCGTTTG
TGTGCCATCGCCACGCAGCGCGCACAGTGCCTGCATCCCCAGGGGGTGGGCAGTATCAGATGTGTAGCCGAGAGCT
CitationKao TJ, Palmesino E, Kania A. SRC family kinases are required for limb trajectory selection by spinal motor axons. J Neurosci. 2009 Apr 29;29(17):5690-700.
CopyrightCopyright © 2009-12 by the Society for Neuroscience
CommentsAuthors indicated the primer for SRC: 5′-TCATAGCCGAATAGCCTCTCCAC-3′. Insufficient information provided in publication to verify exact sequence used to synthesize probe. The sequence below was obtained from NCBI (acc #NM_205457.2)
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
25-26
stage 26
stage 26
Spinal Cord
 

Mouse

EmageMGI:98397
MGI GXDMGI:98397

Frog

Xenbase489819

Fruit Fly

BDGPFBgn0262733

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-030131-3809
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