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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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TNNT2
troponin T2, cardiac type

The human orthologue of this gene is associated
with the following human diseases:

Gene

Official Symbol	TNNT2
Official Full Name	troponin T2, cardiac type
CGNC ID	176
also known as	troponin T, cardiac muscle isoforms\|cardiac troponin T form I\|tnTC\|troponin T type 2 (cardiac), Troponin T, cardiac muscle isoforms , cardiac Troponin T, cTNT, TnTC
gene type	protein-coding

Genomic Map

	Ensembl ID not known
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_205449
Polypeptide	NP_990780
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.4984

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	7139	ENSG00000118194	MIM:115195	MIM:191045
Mouse	21956	ENSMUSG00000026414	All phenotypic alleles (3):Targeted, knock-out(2) Targeted, other(1)	MGI:104597
Xenopus	100493699, 398518			482613
Zebrafish	58071	ENSDARG00000020610	ZDB-GENE-000626-1, ZDB-GENE-091106-2	ZFIN:ZDB-GENE-000626-1, ZFIN:ZDB-GENE-091106-2

Gene Ontology

Molecular Function
Biological Process	regulation of muscle contraction
Cellular Component	troponin complex

Links to other databases

Entrez Gene	396433
Ensembl Gene
KEGG	gga:396433

Entry 1

GEISHA Id	cTNT	Data Source	GEISHA ISH Analysis
Complete cDNA Template Probe	show TTCCCAGATAGCCGCCGGCACCCACCGCTCCGTGGGACCTCGGCACAGGTAGCCAAGCATGTCGGACTCTGAAGAGGTC GTTGAGGAATACGAGCAGGAGCAGGAAGAGGAGTATGTGGAAGAAGAAGAGGAAGAATGGCTTGAGGAAGACGACGGTC AGGAGGATCAGGTAGACGAGGAGGAAGAGGAGACAGAGGAAACCACGGCAGAAGAACAAGAAGATGAAACAAAAGCACC AGGAGAAGGTGGTGAGGGGGACCGGGAGCAGGAGCCTGGGGAAGGTGAATCAAAGCCCAAACCCAAGCCCTTCATGCCC AACCTGGTGCCTCCCAAAATCCCTGATGGCGAGCGCCTGGATTTCGATGACATCCACCGCAAGCGCATGGAGAAGGACC TGAATGAGCTGCAGGCCCTCATCGAAGCCCATTTTGAGAGCAGGAAGAAGGAGGAAGAGGAGCTCATCTCTCTCAAGGA CAGGATTGAGCAGCGGAGGGCAGAGAGGGCAGAGCAGCAGCGCATCCGCAGCGAGAGGGAGAAGGAGCGCCAGGCCCGC ATGGCTGAGGAGAGAGCTCGCAAAGAGGAAGAGGAGGCACGGAAGAAGGCTGAGAAAGAAGCTCGGAAAAAGAAAGCTT TCTCCAACATGCTGCACTTTGGAGGCTACATGCAGAAGTCGGAGAAGAAGGGTGGCAAGAAGCAAACGGAGCGGGAGAA GAAGAAAAAGATCCTCAGCGAGCGGCGGAAGCCTCTGAACATCGACCACCTCAGCGAAGACAAACTGAGGGACAAAGCC AAGGAGCTGTGGCAAACCATCCGTGACCTGGAGGCTGAGAAATTTGACTTGCAGGAGAAGTTCAAGCGGCAGAAGTACG AGATCAACGTCCTTCGAAATCGTGTCAGTGACCACCAGAAGGTCAAAGGGTCAAAGGCTGCCCGTGGGAAGACCATGGT GGGCGGCCGGTGGAAGTAGATGGCTCTGAAGGCAAAGGTGAGGCTCAGCCATCAGATGCAGTGCTGTGCGCTCAACCTA TGCCAGGGCTCTGCTGCCTCCCCACCATGCAGTGCTTGTACAGTGCTTGCTGCTGGCTCCACGCTGCCGGGGTGGGCAG GTGCTCAGCGAGGCGCTGATTCTCATCTCCACACCCCCACATGATGTTGTGTCTGTAAATAAAGAGAGGAGTGAGGGGG

Stage

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Location (click to highlight)

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4-6

stage 4

stage 5

stage 6

Cardiovascular
Early Mesoderm
Splanchnic Mesoderm

heart field
rudiment

7-12

stage 7

stage 8

stage 9

stage 10

stage 11

stage 12

Cardiovascular
Extraembryonic
Heart
Heart Tube
Splanchnic Mesoderm

precardiac region

13-18

stage 13

stage 14

stage 16

Atria
Heart Tube
Myocardium
Myotome
Outflow Tract
Sinus Venosus
Splanchnic Mesoderm
Ventricles

19-20

stage 20

Myocardium
Myotome

Entry 2

GEISHA Id	TroponinT.Salle.2004	Data Source	Publication
Complete cDNA Template Probe	show TTCCCAGATAGCCGCCGGCACCCACCGCTCCGTGGGACCTCGGCACAGGTAGCCAAGCATGTCGGACTCTGAAGAGGTC GTTGAGGAATACGAGCAGGAGCAGGAAGAGGAGTATGTGGAAGAAGAAGAGGAAGAATGGCTTGAGGAAGACGACGGTC AGGAGGATCAGGTAGACGAGGAGGAAGAGGAGACAGAGGAAACCACGGCAGAAGAACAAGAAGATGAAACAAAAGCACC AGGAGAAGGTGGTGAGGGGGACCGGGAGCAGGAGCCTGGGGAAGGTGAATCAAAGCCCAAACCCAAGCCCTTCATGCCC AACCTGGTGCCTCCCAAAATCCCTGATGGCGAGCGCCTGGATTTCGATGACATCCACCGCAAGCGCATGGAGAAGGACC TGAATGAGCTGCAGGCCCTCATCGAAGCCCATTTTGAGAGCAGGAAGAAGGAGGAAGAGGAGCTCATCTCTCTCAAGGA CAGGATTGAGCAGCGGAGGGCAGAGAGGGCAGAGCAGCAGCGCATCCGCAGCGAGAGGGAGAAGGAGCGCCAGGCCCGC ATGGCTGAGGAGAGAGCTCGCAAAGAGGAAGAGGAGGCACGGAAGAAGGCTGAGAAAGAAGCTCGGAAAAAGAAAGCTT TCTCCAACATGCTGCACTTTGGAGGCTACATGCAGAAGTCGGAGAAGAAGGGTGGCAAGAAGCAAACGGAGCGGGAGAA GAAGAAAAAGATCCTCAGCGAGCGGCGGAAGCCTCTGAACATCGACCACCTCAGCGAAGACAAACTGAGGGACAAAGCC AAGGAGCTGTGGCAAACCATCCGTGACCTGGAGGCTGAGAAATTTGACTTGCAGGAGAAGTTCAAGCGGCAGAAGTACG AGATCAACGTCCTTCGAAATCGTGTCAGTGACCACCAGAAGGTCAAAGGGTCAAAGGCTGCCCGTGGGAAGACCATGGT GGGCGGCCGGTGGAAGTAGATGGCTCTGAAGGCAAAGGTGAGGCTCAGCCATCAGATGCAGTGCTGTGCGCTCAACCTA TGCCAGGGCTCTGCTGCCTCCCCACCATGCAGTGCTTGTACAGTGCTTGCTGCTGGCTCCACGCTGCCGGGGTGGGCAG GTGCTCAGCGAGGCGCTGATTCTCATCTCCACACCCCCACATGATGTTGTGTCTGTAAATAAAGAGAGGAGTGAGGGGG
Citation	Sallee D, Qiu Y, Liu J, Watanabe M, Fisher SA. Fas ligand gene transfer to the embryonic heart induces programmed cell death and outflow tract defects. Dev Biol. 2004 Mar 15;267(2):309-19.
Copyright	Copyright © 2004 Elsevier Inc. All rights reserved.
Comments	Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence below was obtained from NCBI (NM_205449).

Stage

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25-30

stage 30

Heart
Myocardium

Entry 3

GEISHA Id	CTNT.Darnell.2010	Data Source	Publication
Complete cDNA Template Probe	show TTCCCAGATAGCCGCCGGCACCCACCGCTCCGTGGGACCTCGGCACAGGTAGCCAAGCATGTCGGACTCTGAAGAGGTC GTTGAGGAATACGAGCAGGAGCAGGAAGAGGAGTATGTGGAAGAAGAAGAGGAAGAATGGCTTGAGGAAGACGACGGTC AGGAGGATCAGGTAGACGAGGAGGAAGAGGAGACAGAGGAAACCACGGCAGAAGAACAAGAAGATGAAACAAAAGCACC AGGAGAAGGTGGTGAGGGGGACCGGGAGCAGGAGCCTGGGGAAGGTGAATCAAAGCCCAAACCCAAGCCCTTCATGCCC AACCTGGTGCCTCCCAAAATCCCTGATGGCGAGCGCCTGGATTTCGATGACATCCACCGCAAGCGCATGGAGAAGGACC TGAATGAGCTGCAGGCCCTCATCGAAGCCCATTTTGAGAGCAGGAAGAAGGAGGAAGAGGAGCTCATCTCTCTCAAGGA CAGGATTGAGCAGCGGAGGGCAGAGAGGGCAGAGCAGCAGCGCATCCGCAGCGAGAGGGAGAAGGAGCGCCAGGCCCGC ATGGCTGAGGAGAGAGCTCGCAAAGAGGAAGAGGAGGCACGGAAGAAGGCTGAGAAAGAAGCTCGGAAAAAGAAAGCTT TCTCCAACATGCTGCACTTTGGAGGCTACATGCAGAAGTCGGAGAAGAAGGGTGGCAAGAAGCAAACGGAGCGGGAGAA GAAGAAAAAGATCCTCAGCGAGCGGCGGAAGCCTCTGAACATCGACCACCTCAGCGAAGACAAACTGAGGGACAAAGCC AAGGAGCTGTGGCAAACCATCCGTGACCTGGAGGCTGAGAAATTTGACTTGCAGGAGAAGTTCAAGCGGCAGAAGTACG AGATCAACGTCCTTCGAAATCGTGTCAGTGACCACCAGAAGGTCAAAGGGTCAAAGGCTGCCCGTGGGAAGACCATGGT GGGCGGCCGGTGGAAGTAGATGGCTCTGAAGGCAAAGGTGAGGCTCAGCCATCAGATGCAGTGCTGTGCGCTCAACCTA TGCCAGGGCTCTGCTGCCTCCCCACCATGCAGTGCTTGTACAGTGCTTGCTGCTGGCTCCACGCTGCCGGGGTGGGCAG GTGCTCAGCGAGGCGCTGATTCTCATCTCCACACCCCCACATGATGTTGTGTCTGTAAATAAAGAGAGGAGTGAGGGGG
Citation	Darnell DK, Stanislaw S, Kaur S, Antin PB. Whole mount in situ hybridization detection of mRNAs using short LNA containing DNA oligonucleotide probes. RNA. 2010 March; 16(3): 632637.
Copyright	Copyright © 2010 RNA Society
Comments	Probes were multiple LNAs whose sequences can be found at http://rnajournal.cshlp.org/content/suppl/2010/01/08/rna.1775610.DC1/Supp_figs_S1_S3.pdf. NCBI (acc #NM_205449.1) is given for reference only.

Stage

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Location (click to highlight)

Comments (click to highlight)

19-24

stage 24

Heart Tube
Somites

Entry 4

GEISHA Id	cTNT.Antin.2002	Data Source	Publication
Complete cDNA Template Probe	show `CAAACTGAGGGACAAAGCCAAGGAGCTGTGGCAAACCATCCGTGACCTGGAGGCTGAGAAATTTGACTTGCAGGAGAAG TTCAAGCGGCAGAAGTACGAGATCAACGTCCTTCGAAATCGTGTCAGTGACCACCAGAAGGTCAAAGGGTCAAAGGCTG CCCGTGGGAAGACCATGGTGGGCGGCCGGTGGAAGTAGATGGCTCTGAAGGCAAAGGTGAGGCTCAGCCATCAGATGCA GTGCTGTGCGCTCAACCTATGCCAGGGCTCTGCTGCCTCCCCACCATGCAGTGCTTGTACAGTGCTTGCTGCTGGCTCC ACGCTGCCGGGGTGGGCAGGTGCTCAGCGAGGCGCTGATTCTCATCTCCACACCCCCA`
Citation	Antin PB, Bales MA, Zhang W, Garriock RJ, Yatskievych TA, Bates MA. Precocious expression of cardiac troponin T in early chick embryos is independent of bone morphogenetic protein signaling. Dev Dyn. 2002 Oct;225(2):135-41.
Copyright	Copyright © 2002 Wiley‐Liss, Inc.
Comments	The complete cDNA template sequence was obtained from information referenced in the publication as described in Antin et al. 2002. cTNT gene name is also known as TNNT2 in NCBI.