GEISHA - A Chicken Embryo Gene Expression Database
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TGFB3
transforming growth factor beta 3

The human orthologue of this gene is associated
with the following human disease:
Gene
Official SymbolTGFB3
Official Full Nametransforming growth factor beta 3
CGNC ID7874
also known asTGF-beta-3, TGF-beta3, transforming growth factor beta-3 proprotein|TGF beta 3|transforming growth factor-beta3, TGF-beta-3, Transforming growth factor beta-3 precursor
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_205454
PolypeptideNP_990785
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.42150
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly
Human7043MIM:107970MIM:190230
Mouse21809ENSMUSG00000021253All phenotypic alleles (5):Targeted, knock-out(4) Targeted, other(1) MGI:98727
Xenopus
Zebrafish369195ENSDARG00000019367ZDB-GENE-030723-4ZFIN:ZDB-GENE-030723-4
Gene Ontology
Molecular Functiongrowth factor activity, transforming growth factor beta receptor binding
Biological Processcardiac epithelial to mesenchymal transition, cell activation, cell growth, more...embryonic digestive tract development, epithelial to mesenchymal transition involved in endocardial cushion formation, mesenchyme migration, negative regulation of cell adhesion, nervous system development, positive regulation of cell division, positive regulation of cell migration, positive regulation of transcription, DNA-templated, spleen development
Cellular Componentextracellular space
Links to other databases
Entrez Gene396438
Ensembl GeneENSGALG00000010346
KEGGgga:396438

Entry 1

GEISHA IdChEST357l20Data SourceGEISHA ISH Analysis
Forward cDNA Template Probeshow
GCGGCTCGAGGCGGCTTGAGGCGGCTCGAGATCTGCTTCACCCTGCTGTGTCCCACAGGACCTGGAGCCACTGACGATC
TTGTACTATGTTGGGAGGACACCCAAAGTGGAGCAGCTCTCCAATATGGTGGTGAAATCCTGCAAGTGCAGCTGAAAGG
CACCCTGGGCTGCCCAAAGCCTAGAAAGAAACTGTCAGCACCCATTCTGCTCCAAGGCTAGCACAAAAGGAACTGGGGG
TCAGAGACTATGCATGCAGAGGGCCGAGTGCTAAACCTTGTGGCTTAGGGTCTGGCAGTCCTTGGGAACCTCTTCTGGA
ACATTTCTCGGTCTTGTTGCCAGTGTCGCGTTCCCTCTGGGAGTTGCTTTGACGACACAAAGACCACACTCCAAAATGA
CTGGACAGTTGATGCGGAAGAGAAAGACAGTGAAGGAACTGCTGTGTATCTGAATGCTGGGGTAGTTGAACTGGGAAGG
CAAGGAATGAGAAAGAGCAGTCCATTTATAGGAGGACCGATGTCTCTATTCAGCTCTTTTCCCTTTCTGGAGTTCCTGA
AAGATGGTTTCTGGGGCAGGGCGAGAGCATTATCTGGGGGTACCTGGATTTTGGAGCCATTCACTCATGATCTGATAAC
ACTCTGAGGACCTTTTGTCTGTTGTGGTTTGTGATCTCAACGTGGCCCAAGCCTCACCTGCCAAGACTT
CommentsNo specific expression detected stage 3-5.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-12
stage 11
Heart Tube
Ventricles
 
13-18
stage 15
stage 17
Aorta
Arteries
Atria
Blood Vessels
Head Process
Heart Tube
Hindbrain
Myotome
Notochord
Ventricles
 
19-24
stage 19
stage 20
Aorta
Arteries
Atria
Blood Vessels
Myotome
Outflow Tract
Sinus Venosus
Ventricles
 
25
stage 25
Allantois
Aorta
Arteries
Atria
Blood Vessels
Myotome
Outflow Tract
Sinus Venosus
Ventricles
 

Entry 2

GEISHA IdTGFB3.UApcrData SourceGEISHA ISH Analysis
Forward cDNA Template PrimerGGGCGATGGAGAAAAATGC
Reverse cDNA Template PrimerATTAA CCCTCACTAAAGGATGTAGTAGAGGATGGTGAGGGGCcDNA Template Length743
Complete cDNA Template Probeshow
ATTTGCCCAATGGGGACATCTTGGAGAACTTACATGAGGTCTTGGAGATCAAATTCAAAGGCATTGACAGTGAAGATGA
CTATGGCCGTGGGGACTTGGGGCGCCTGAAGAAGCAGAAAGACTTGCATAATCCCCACCTCATCTTGATGATGCTACCC
CCACATCGCCTGGAGAGCCCAACACTGGGAGGCCAGAGAAAGAAGCGGGCCCTGGATACCAACTACTGCTTCCGGAACC
TGGAGGAGAACTGCTGTGTGCGTCCTCTTTACATTGACTTCCGACAGGACCTGGGCTGGAAATGGGTCCATGAGCCTAA
AGGCTACTTTGCAAACTTCTGTTCGGGCCCATGTCCGTACCTCCGCAGTGCAGACACCACTCACAGCACGGTGCTGGGC
TTGTACAACACGCTGAACCCCGAGGCATCTGCTTCACCCTGCTGTGTCCCACAGGACCTGGAGCCACTGACGATCTTGT
ACTATGTTGGGAGGACACCCAAAGTGGAGCAGCTCTCCAATATGGTGGTGAAATCCTGCAAGTGCAGCTGAAAGGCACC
CTGGGCTGCCCAAAGCCTAGAAAGAAACTGTCAGCACCCATTCTGCTCCAAGGCTAGCACAAAAGGAACTGGGGGTCAG
AGACTATGCATGCAGAGGGCCGAGTGCTAAACCTTGTGGCTTAGGTCTGGCAGTCT
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-6
stage 4
stage 5
stage 6
Blood Islands
Early Mesoderm
Epiblast
Extraembryonic Mesoderm
Lateral Plate Mesoderm
Primitive Streak
 
7-12
stage 8
stage 9
stage 10
stage 11
stage 11
stage 11
Anterior Intestinal Portal
Area Opaca
Area Pellucida
Blood Islands
Blood Vessels
Extraembryonic Mesoderm
Head Mesenchyme
Heart
Heart Tube
Lateral Plate Mesoderm
Mesoderm
Myocardium
Neural Plate/Tube
Notochord
Paraxial Mesoderm
Somites
Sections pending.
13-18
stage 15
stage 15
stage 16
stage 17
stage 18
stage 18
stage 18
stage 18
Blood Islands
Blood Vessels
Head Mesenchyme
Heart
Myotome
Notochord
Paraxial Mesoderm
Pharyngeal Arches and Clefts
Somites
 
19-24
stage 21
Allantois
Head Mesenchyme
Leg
Myocardium
Pharyngeal Arches and Clefts
Somites
Wing
Sections pending.
25
stage 25
stage 25
stage 25
Allantois
Blood Vessels
Forebrain
Heart
Leg
Leg Mesenchyme
Mesonephros
Midbrain
Pharyngeal Arches and Clefts
Somatic Mesoderm
Somites
Wing
Wing Mesenchyme
 
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.42150

Mouse

EmageMGI:98727
EurexpressMGI:98727
MGI GXDMGI:98727

Frog

Xenbase

Fruit Fly

BDGP

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-030723-4
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