GEISHA - A Chicken Embryo Gene Expression Database
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HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)

Gene
Official SymbolHSPA5
Official Full Nameheat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
CGNC ID667
also known asGRP78, endoplasmic reticulum chaperone BiP|78 kDa glucose-regulated protein|GRP-78|HSP70 family protein 5|biP|binding-immunoglobulin protein|heat shock 70 kDa protein 5|heat shock protein 70 family protein 5|heat shock protein family A member 5|immunoglobulin heavy chain-binding protein, 78 kDa glucose-regulated protein precursor (GRP 78), Immunoglobulin heavy chain binding protein
gene typeprotein-coding
Genomic Map
 Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
RNANM_205491
PolypeptideNP_990822
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
EST ProfileGga.4219
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Fruit Fly32133FBgn0001218
Human3309ENSG00000044574MIM:138120
Mouse14828ENSMUSG00000026864All phenotypic alleles (4):Targeted, knock-out(2) Targeted, other(2) MGI:95835
Xenopus100492570, 379756480059
Zebrafish378848ENSDARG00000004665ZDB-GENE-031001-11ZFIN:ZDB-GENE-031001-11
Gene Ontology
Molecular FunctionATP binding, misfolded protein binding, protein binding, protein domain specific binding, ribosome binding, more...ubiquitin protein ligase binding
Biological Processactivation of signaling protein activity involved in unfolded protein response, more...cellular response to glucose starvation, cellular response to interleukin-4, cerebellar Purkinje cell layer development, cerebellum structural organization, ER overload response, negative regulation of apoptotic process, negative regulation of transforming growth factor beta receptor signaling pathway, positive regulation of protein ubiquitination, proteolysis involved in cellular protein catabolic process
Cellular Componentcell surface, COP9 signalosome, endoplasmic reticulum chaperone complex, more...endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum lumen, integral component of endoplasmic reticulum membrane, midbody
Links to other databases
Entrez Gene396487
Ensembl GeneENSGALG00000001000
KEGGgga:396487

Entry 1

GEISHA IdR24Data SourceGEISHA ISH Analysis
Forward cDNA Template Probeshow
GTGGAGACGCGACGGTTCGTGTGTGACGAGCGGCGAGCGGGCGGCATGAGGCACCTCCTGTTGGCGCTGCTGCTGCTGG
GCGGCGCGCGGGCGGACGATGAGGAGAAAAAGGAGGACGTGGGCACGGTGGTGGGCATCGACCTCGGTACCACCTATTC
TTGTGTGGGTGTATTCAAGAACGGCCGCGTGGAAATCATTGCCAATGACCAGGGGAACCGCATCACGCCATCCTACGTG
GCGTTCACGCCTGAGGGGGAGCGCCTGATTGGGGATGCAGCCAAGAACCAGCTGACATCCAACCCTGAGAACACTGTGT
TTGATGCCAAGCGGCTCATAGGCCGCACCTGGAATGACCCCTCTGTACAGCAGGACATCAAGTATCTGCCCTTCAAGGT
TGTTGAAAAGAAGGCCAAGCCACATATTCAGGTCGATGTTGGTGGTGGACAAACAAAAACATTTGCTCCTGAAGAAATT
TCTGCCATGGTCCTGACAAAGATGAAAGAAACTGCAGAGGCTTATCTGGGCAAGAAAGTTACTCATGCTGTTGTTACTG
TGCCAGCCTACTTCAATGATGCTCAGCGTCAGGCCACAAAAGATGCTGGTACTATTGCTGGGTTGAACGTGATGCGCAT
TATTAA
Commentsnegative stages 13-22
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-12
stage 8
stage 12
stage 12
Anterior Intestinal Portal
Area Opaca
Endoderm, early
Extraembryonic
Notochord
Surface Ectoderm
 

Entry 2

GEISHA IdG40Data SourceGEISHA ISH Analysis
Forward cDNA Template Probeshow
GGTTGGAGACGCGACGGTTCGTGTGTGACGAGCGGCGAGCGGGCGGCATGAGGCACCTCCTGTTGGCGCTGCTGCTGCT
GGGCGGCGCGCGGGCGGACGATGAGGAGAAAAAGGAGGACGTGGGCACGGTGGTGGGCATCGACCTCGGTACCACCTAT
TCTTGTGTGGGTGTATTCAAGAACGGCCGCGTGGAAATCATTGCCAATGACCAGGGGAACCGCATCACGCCATCCTACG
TGGCGTTCACGCCTGAGGGGGAGCGCCTGATTGGGGATGCAGCCAAGAACCAGCTGACATCCAACCCTGAGAACACTGT
GTTTGATGCCAAGCGGCTCATAGGCCGCACCTGGAATGACCCCTCTGTACAGCAGGACATCAAGTATCTGCCCTTCAAG
GTTGTTGAAAAGAAGGCCAAGCCACATATTCAGGTCGATGTTGGTGGTGGACAAACAAAAACATTTGCTCCTGAAGAAA
TTTCTGCCATGGTCCTGACAAAGATGAAAGAAACTGC
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
1-3
 
stage 2
Unlabeled Embryonic
 
4-6
stage 4
stage 4
stage 4
stage 6
Endoderm, early
Germinal Crescent
Head Process
Hensen's Node
Surface Ectoderm
 
13-17
stage 16
stage 17
Unlabeled Extraembryonic
Widespread Expression
 

Entry 3

GEISHA IdP40Data SourceGEISHA ISH Analysis
Forward cDNA Template Probeshow
GGACGGTTCGTGTGTGACGAGCGGCGAGCGGGCGGCATGAGGCACCTCCTGTTGGCGCTGCTGCTGCTGGGCGGCGCGC
GGGCGGACGATGAGGAGAAAAAGGAGGACGTGGGCACGGTGGTGGGCATCGACCTCGGTACCACCTATTCTTGTGTGGG
TGTATTCAAGAACGGCCGCGTGGAAATCATTGCCAATGACCAGGGGAACCGCATCACGCCATCCTACGTGGCGTTCACG
CCTGAGGGGGAGCGCCTGATTGGGGATGCAGCCAAGAACCAGCTGACATCCAACCCTGAGAACACTGTGTTTGATGCCA
AGCGGCTCATAGGCCGCACCTGGAATGACCCCTCTGTACAGCAGGACATCAAGTATCTGCCCTTCAAGGTTGTTGAAAA
GAAGGCCAAGCCACATATTCAGGTCGATGTTGGTGGTGGACAAACAAAAACATTTGCTCCTGAAGAAATTTCTGCCATG
GTCCTGACAAAGATGAAAGAAACTGCAGAGGCTTATCTGGGCAAGAAAGTTACTCATGCTGTTGTTACTGTGCCAGCCT
ACTTCAATGATGCTCAGCGTCAGGCCACAAAAGATGCTGGTACTATTGCTGGGTTGAACGTGATGCGCATTATTAAT
Commentsstages 14, 15, 22 negative for embryonic expression
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
7-12
stage 10
stage 12
stage 12
Endoderm, early
Extraembryonic
 

Entry 4

GEISHA IdGRP78.Bell.2004Data SourcePublication
Forward cDNA Template Probeshow
GGTTGGAGACGCGACGGTTCGTGTGTGACGAGCGGCGAGCGGGCGGCATGAGGCACCTCCTGTTGGCGCTGCTGCTGCT
GGGCGGCGCGCGGGCGGACGATGAGGAGAAAAAGGAGGACGTGGGCACGGTGGTGGGCATCGACCTCGGTACCACCTAT
TCTTGTGTGGGTGTATTCAAGAACGGCCGCGTGGAAATCATTGCCAATGACCAGGGGAACCGCATCACGCCATCCTACG
TGGCGTTCACGCCTGAGGGGGAGCGCCTGATTGGGGATGCAGCCAAGAACCAGCTGACATCCAACCCTGAGAACACTGT
GTTTGATGCCAAGCGGCTCATAGGCCGCACCTGGAATGACCCCTCTGTACAGCAGGACATCAAGTATCTGCCCTTCAAG
GTTGTTGAAAAGAAGGCCAAGCCACATATTCAGGTCGATGTTGGTGGTGGACAAACAAAAACATTTGCTCCTGAAGAAA
TTTCTGCCATGGTCCTGACAAAGATGAAAGAAACTGC
CitationBell GW, Yatskievych TA, Antin PB. GEISHA, a whole-mount in situ hybridization gene expression screen in chicken embryos. Dev Dyn. 2004 Mar;229(3):677-87.
CopyrightCopyright © 2004 Wiley-Liss, Inc.
CommentsThe probe sequence below was obtained from the GEISHA database using information provided in the publication, GEISHA G40.
StageImage (click image to view full size)Location (click to highlight)Comments (click to highlight)
4-5
stage 5
stage 5
Head Process
Hensen's Node
 
 Data from NCBI Unigene EST Profile
Unigene ID: Gga.4219

Mouse

EmageMGI:95835
EurexpressMGI:95835
MGI GXDMGI:95835

Frog

Xenbase480059

Fruit Fly

BDGPFBgn0001218

Zebra Finch

ZEBrA

Zebrafish

ZFINZDB-GENE-031001-11
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