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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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CBFB
core-binding factor beta subunit

The human orthologue of this gene is associated
with the following human disease:

Myeloid leukemia, acute, M4/M4Eo subtype, somatic

Gene

Official Symbol	CBFB
Official Full Name	core-binding factor beta subunit
CGNC ID	2299
also known as	core-binding factor subunit beta, core-binding factor, beta subunit , Cbfb
gene type	protein-coding

Genomic Map

	Ensembl ID not known
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_204570
Polypeptide	NP_989901
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.9351

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	38198			FBgn0013753
Human	865	ENSG00000067955	MIM:601626	MIM:121360
Mouse	12400	ENSMUSG00000031885	All phenotypic alleles (13):Targeted, knock-out(4) Targeted, other(9)	MGI:99851
Xenopus	100270773, 446882			1016002
Zebrafish	30744	ENSDARG00000040917	ZDB-GENE-980526-440	ZFIN:ZDB-GENE-980526-440

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Links to other databases

Entrez Gene	395257
Ensembl Gene
KEGG	gga:395257

Entry 1

GEISHA Id	CBFB.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	GGGAACCAATCTGTCTCTCC
Reverse cDNA Template Primer	ATTAACCCTCACTAAAGGGCAGTTTGTAGGTCTTGCG	cDNA Template Length	957
Forward cDNA Template Probe	show CGGGAACCAATCTGTCTCTCCAGTTTTTTCCGGCCAGCTGGCAGGGGGAGCAGCGGCAGACACCAACCCGGGAGTATGT CGACTTTGAGAGAGAAGGAGGCAAGGTGTACTTGAAGGCACCTATGATTCTTAATGGTGTCTGTGTAATCTGGAAAGGC TGGATAGATCTACAGAGACTGGATGGTATGGGCTGCCTGGAATTTGATGAAGAGAGAGCACAGCAGGAGGATGCATTGG CACAACAAGCCTTTGAAGAAGCTCGAAGAAGAACCCGTGAATTCGAAGACAGAGACAGGTCTCATCGGGAGGAAATGGA GGTGAGGGTTTCACAGCTGCTGTCAGTAACTGGCAAGAAGACAACAAGACCCTAGTCCTGGATCCAACCTAGGAAGTGG TGATGATCTCAAACTACGTTAATCAGCATCAACAGTGCCATGGGTCTGCAACATGCATTGCTTCTACTTGGCAAAGGAT TGAATAAAGACCAGAAACTGTGATAACTGGGTATATTATGGTCTGTTTCCTGACCTGCGGCAGTCAGAACCACCGTGAA CTGCCATGGTTTGCACTATGTTTATGTTACGATACCTGCATTTCCCATGTTAAGCATGTAGCCAGTGGCAATTTGAAAT TTTGTTTTTCTATGCAAACTTTTGTTGGCACTATTTTAGTGAAATGGAAACTTATGCAGCTATAAAAACATTTTTTTCT CAATTGTAATAAAAATTGTCACTTAAAAATAGGTCAAGGTATTACAGATTAAAAACTTTTTTGTTTCTGTTTTTTTTTT TTTTTTTTTGTAAACTGCTGGAAGCCAATGCATTCCAAGCTTAATTTTTTTAATATGGGCTTTTGGAGTTTTGATTGTC CTTCTTGTGCTCCTGCTTTATTTTAGATATGCGTTCTTATCTTTCCTTCTTATTTCTTTTTTTCTACATTCGCAAGACC TACAAACTGC

Stage

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Location (click to highlight)

Comments (click to highlight)

4-6

stage 4

stage 5

stage 6

Area Opaca
Area Pellucida
Blood Islands
Hensen's Node
Lateral Plate Mesoderm
Neural Plate/Tube
Primitive Streak

7-12

stage 7

stage 8

stage 9

stage 11

Anterior/Second Heart Field
Blood
Blood Islands
Blood Vessels
Forebrain
Head Mesenchyme
Headfold
Hensen's Node
Hindbrain
Intermediate Mesoderm
Lateral Plate Mesoderm
Midbrain
Neural Plate/Tube
Primitive Streak
Somites

13-18

stage 13

stage 17

stage 18

Anterior/Second Heart Field
Blood Islands
Cranial Ganglia
Endocardium
Face Mesenchyme
Forebrain
Head Mesenchyme
Intermediate Mesoderm
Isthmus/MHB
Lateral Plate Mesoderm
Limb Buds
Lung
Midbrain
Neural Plate/Tube
Pharyngeal Arches and Clefts
Pharynx
Somatic Mesoderm
Somites
Spinal Ganglia and Nerves

19-24

stage 21

Allantois
Cranial Ganglia
Face Mesenchyme
Forebrain
Isthmus/MHB
Limb Buds
Lung
Midbrain
Pharyngeal Arches and Clefts
Somites
Spinal Ganglia and Nerves

25-26

stage 25

stage 26

Allantois
Anterior/Second Heart Field
Cranial Ganglia
Eye
Gut
Lateral Plate Mesoderm
Leg Mesenchyme
Lung
Outflow Tract
Pharyngeal Arches and Clefts
Somatic Mesoderm
Spinal Cord
Spinal Ganglia and Nerves
Wing Mesenchyme

Entry 2

GEISHA Id	CBFB.Bollerot.2005	Data Source	Publication
Complete cDNA Template Probe	show GGACAGCGCGGGGCGGGCGGAGGGCAGCGGCGGCCCGGCACCATGCCGCGGGTCGTCCCCGACCAGCGCANAAGTTCGA GAACGAGGAGTTCTTCAGGAAGCTGAGCCGCGAGTGCGAGATCAAGTACACCGGCTTCAGGGACCGGTCCCACGAGGAG AGGCAGGCCCGCTTCCAGAACGCCTGCCGCGACGGCCGCTCCGAGATCGCTTTTGTGGCCACGGGAACCAATCTGTCTC TCCAGTTTTTTCCGGCCAGCTGGCANGGGGAGCAGCGGCAGACACCAACCCGGGAGTATGTCGACTTTGAGAGAGAAGG AGGCAAGGTGTACTTGAAGGCACCTATGATTCTTAATGGTGTCTGTGTAATCTGGAAAGGCTGGATAGATCTACAGAGA CTGGATGGTATGGGCTGCCTGGAATTTGATGAAGAGAGAGCACAGCAGGAGGATGCATTGGCACAACAAGCCTTTGAAG AAGCTCGAAGAAGAACCCGTGAATTCGAAGACAGAGACAGGTCTCATCCGGAGGAAAATNGANGTNAAGGTTTTCACAN CTGCTGTCAGTAACTTGCA
Citation	Bollerot K, Romero S, Dunon D, Jaffredo T. Core binding factor in the early avian embryo: cloning of Cbfbeta and combinatorial expression patterns with Runx1. Gene Expr Patterns. 2005 Dec;6(1):29-39. Epub 2005 Jul 19.
Copyright	Copyright © 2005 Elsevier B.V. All rights reserved.
Comments	Sequence below was obtained from the Chick EST database at Delaware Biothechnology Institute (http://www.chickest.udel.edu/) using the EST name (pat.pk0013.c6) provided by the authors. Sequence can also be located in NCBI under the GenBank Accession No. AI980132.