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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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ISL2
ISL LIM homeobox 2

Gene

Official Symbol	ISL2
Official Full Name	ISL LIM homeobox 2
CGNC ID	49781
also known as	ISLET-2, insulin gene enhancer protein ISL-2\|domesticus (clone 1.6 kB) islet-2
gene type	protein-coding

Genomic Map

	Ensembl ID not known
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	L35568
Polypeptide	AAA62172
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.790

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human
Mouse
Xenopus
Zebrafish

Gene Ontology

Molecular Function	sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, more...zinc ion binding
Biological Process	multicellular organismal development
Cellular Component	nucleus

Links to other databases

Entrez Gene	396382
Ensembl Gene
KEGG

Entry 1

GEISHA Id	Islet2.UApcr	Data Source	GEISHA ISH Analysis
Complete cDNA Template Probe	show `AAGCGGCCGAGAAGACCACCCGCGTGCGGACGGTGCTGAACGAGAAGCAGCTGCACACGCTGCGGACCTGCTACGCCGC CAACCCGAGACCCGACGCCCTGATGAAGGAGCAGCTGGTGGAGATGACGGGGCTCAGCCCGCGCGTCATCCGCGTCTGG TTCCAGAACAAGCGCTGCAAGGACAAGAAGAAGTCCATCCTCATGAAGCAGCTCCAGCAGCAGCAGCACAGCGACAAGA CGAGCCTGCAGGGCCTCACCGGGACGCCGCTGGTGGCCGGCAGCCCCGTCCGGCACGAGAGCGCCGTGCAGGGGAGCGC GGTGGAGGTGCAGACCTACCAGCCGCCCTGGAAGGCGCTCAGCGACTTCGCGCTGCAGAGCGACCTGGAG`

Stage

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Location (click to highlight)

Comments (click to highlight)

4-6

stage 4

stage 6

Ectoderm
Endoderm
Epiblast
Headfold
Heart
Lateral Plate Mesoderm
Primitive Streak
Unlabeled

heart field

7-12

stage 7

Anterior Intestinal Portal
Endoderm
Head Mesenchyme
Lateral Plate Mesoderm
Neural Plate/Tube
Primitive Streak

heart field
heart fields

13-18

stage 13

stage 14

stage 15

stage 16

stage 17

Anterior Intestinal Portal
Cranial PNS
Diencephalon
Ear/Otic Placode
Ectoderm
Foregut
Head Mesenchyme
Hindbrain
Hindgut
Lateral Plate Mesoderm
Midbrain
Neural Plate/Tube
Oral Pharynx
Pancreas
Pharyngeal Arches and Clefts
Pharynx
Surface Ectoderm
Tail

19-21

stage 20

stage 21

Allantois
Cranial PNS
Hindgut
Leg AER
Midbrain
Neural Plate/Tube
Oral Pharynx
Pancreas
Pharyngeal Arches and Clefts
Surface Ectoderm

Entry 2

GEISHA Id	ISL2.Guidato.2003	Data Source	Publication
Complete cDNA Template Probe	show TTCCTGCTGCGGGTGTCTCCGGACCTGGAGTGGCACGTCGCCTGCCTCAAGTGCGCCGAGTGCGGGCAGCCGCTGGACG AGACCTGCACGTGCTTCCTGCGCGACGGCAAGGCCTACTGCAAGCGGGACTACGGCAGGCTCTTCGGCATCAAGTGCGC GCAGTGCCGGGCGGCCTTCAGCAGCAGCGACCTGGTGATGCGCGCCCGCGACCACGTCTACCACCTGGAGTGCTTCCGC TGCGCCGCCTGCGGCCGCCAGCTGCTGCCCGGGGATCAGTTCTGCCTGCGGGAGCGCGACCTGCTCTGCCGCGCCGACC ACGGGCCGCCCCCCGACGGCGCCGCCGCCCGCGGGCCCCGCAGCCCCGCGCCGCCGCCCGCGCACCTCGCAGAGCCGGT GCCCGGACGGCCGCCCGGCCCGCGGCCGCAGTCGCACAAAGCGGCCGAGAAGACCACCCGCGTGCGGACGGTGCTGAAC GAGAAGCAGCTGCACACGCTGCGGACCTGCTACGCCGCCAACCCGAGACCCGACGCCCTGATGAAGGAGCAGCTGGTGG AGATGACGGGGCTCAGCCCGCGCGTCATCCGCGTCTGGTTCCAGAACAAGCGCTGCAAGGACAAGAAGAAGTCCATCCT CATGAAGCAGCTCCAGCAGCAGCAGCACAGCGACAAGACGAGCCTGCAGGGCCTCACCGGGACGCCGCTGGTGGCCGGC AGCCCCGTCCGGCACGAGAGCGCCGTGCAGGGGAGCGCGGTGGAGGTGCAGACCTACCAGCCGCCCTGGAAGGCGCTCA GCGACTTCGCGCTGCAGAGCGACCTGGAGCCGCCCGCCGCCTTCCAGCAGCTGGTCTCCTTCTCCGAGTCCGGCTCTTT GGGCACGTCCTCCGGCAGCGACGTGACCTCGCTGTCCTCCCAGCTCCCCGACACCCCCAACAGCATGGTGCCCAGCCCG GCCGAGACGTGA
Citation	Guidato S, Prin F, Guthrie S. Somatic motoneurone specification in the hindbrain: the influence of somite-derived signals, retinoic acid and Hoxa3. Development. 2003 Jul;130(13):2981-96.
Copyright	Published by The Company of Biologists 2003. This material is protected by a copyright retained by the authors.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #AB179553.1 ).

Stage

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Location (click to highlight)

Comments (click to highlight)

25-28

stage 28

Isthmus/MHB
Rhombomeres
Spinal Cord

Entry 3

GEISHA Id	ISL2.Anderson.2021	Data Source	Direct Submission
Complete cDNA Template Probe	show TTGTTGTTCGTTTGTTTTTATTAAGTCCAAAATATTTAACCCCACTATTCAACCGCTGACTCTGACAATAAATAGCAAT AACTTACTTTTGTTCGTTTAAAGGCTCAAACAATCCGCCCTCCGTCCGTCGCTATCGCCGGCAGCGCTGTCCCGTCGCA GCGCCCCGTCTCCGCGCCGCGGTGCTGCGGGAGGCGCCGGCGTGAGGCGGCCGCGACGGCCGCGGGGCTCCGACCCCCG TTCGGTTTGATTCGAGTTTTCGTTTCTGTTCCAGGCGAGGAAGAAGAGCCGGCGCCCCGCCGGGCAATCCGCTTTCATC GCGGAAAAGAAACATCGAAATCCGCAGCGCCGAACCTCCGCGCAACGAAATGAGCGGGGCGGGGGCTCGCTCTCTCTTT CTCTCTCCGGTCCGGTGAAGGCAGCGAGAATCCCGGCGCTTTTCGGCCGTCGGCAAGGTACGTTCGGTTTGGTTTTAAA TAGGAATAATTAAAAGACAAAGGCGCTCGTCCGGCGCGCTGGGCGCGGCGCGGGGCCGGGTGTCTCATGCAGGGAGCGC GGCATGCGGAGGTCCCGCGGCGGCGGGGGCCGGGCGGCCTCACGTCTCGGCCGGGCTGGGCACCATGCTGTTGGGGGTG TCGGGGAGCTGGGAGGACAGCGAGGTCACGTCGCTGCCGGAGGACGTGCCCAAAGAGCCGGACTCGGAGAAGGAGACCA GCTGCTGGAAGGCGGCGGGCGGCTCCAGGTCGCTCTGCAGCGCGAAGTCGCTGAGCGCCTTCCAGGGCGGCTGGTAGGT CTGCACCTCCACCGCGCTGCCCTGCACGGCGCTCTCGTGCCGGACGGGGCTGCCGGCCACCAGCGGCGTCCCGGTGAGG CCCTGCAGGCTCGTCTTGTCGCTGTGCTGCTGCTGCTGGAGCTGCTTCATGAGGATGGACTTCTTCTTGTCCNTGCAGC GCTTGTNCTGGAACCAGACGCGNATGANNNNNNGGCTGANCCCCGTCATCTCCNNNGCTGCTNCTTCATC
Comments	Images and probe sequence provided by Claire Anderson. Reference paper for probe: T.Tsuchida, M.Ensini, S.B.Morton, M.Baldassare, T.Edlund†T.M.Jessell, S.L.Pfaff. Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes. Cell, Volume 79, Issue 6, 16 December 1994, Pages 957-970.