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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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ISL2
ISL LIM homeobox 2

Gene

Official Symbol	ISL2
Official Full Name	ISL LIM homeobox 2
CGNC ID	49781
also known as	ISLET-2, insulin gene enhancer protein ISL-2\|domesticus (clone 1.6 kB) islet-2
gene type	protein-coding

Genomic Map

	Ensembl ID not known
	NCBI
	UCSC

Sequence Information

Genomic
RNA	L35568
Polypeptide	AAA62172

Gene Expression

In Situ Hybridization

GEISHA

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human
Mouse
Xenopus
Zebrafish

Gene Ontology

Molecular Function	sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, more...zinc ion binding
Biological Process	multicellular organismal development
Cellular Component	nucleus

Links to other databases

Entrez Gene	396382
Ensembl Gene
KEGG

Entry 1

GEISHA Id	Islet2.UApcr	Data Source	GEISHA ISH Analysis
Complete cDNA Template Probe	show `AAGCGGCCGAGAAGACCACCCGCGTGCGGACGGTGCTGAACGAGAAGCAGCTGCACACGCTGCGGACCTGCTACGCCGC CAACCCGAGACCCGACGCCCTGATGAAGGAGCAGCTGGTGGAGATGACGGGGCTCAGCCCGCGCGTCATCCGCGTCTGG TTCCAGAACAAGCGCTGCAAGGACAAGAAGAAGTCCATCCTCATGAAGCAGCTCCAGCAGCAGCAGCACAGCGACAAGA CGAGCCTGCAGGGCCTCACCGGGACGCCGCTGGTGGCCGGCAGCCCCGTCCGGCACGAGAGCGCCGTGCAGGGGAGCGC GGTGGAGGTGCAGACCTACCAGCCGCCCTGGAAGGCGCTCAGCGACTTCGCGCTGCAGAGCGACCTGGAG`

Stage

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Location (click to highlight)

Comments (click to highlight)

4-6

stage 4

stage 6

Ectoderm
Endoderm
Epiblast
Headfold
Heart
Lateral Plate Mesoderm
Primitive Streak
Unlabeled

heart field

7-12

stage 7

Anterior Intestinal Portal
Endoderm
Head Mesenchyme
Lateral Plate Mesoderm
Neural Plate/Tube
Primitive Streak

heart field
heart fields

13-18

stage 13

stage 14

stage 15

stage 16

stage 17

Anterior Intestinal Portal
Cranial PNS
Diencephalon
Ear/Otic Placode
Ectoderm
Foregut
Head Mesenchyme
Hindbrain
Hindgut
Lateral Plate Mesoderm
Midbrain
Neural Plate/Tube
Oral Pharynx
Pancreas
Pharyngeal Arches and Clefts
Pharynx
Surface Ectoderm
Tail

19-21

stage 20

stage 21

Allantois
Cranial PNS
Hindgut
Leg AER
Midbrain
Neural Plate/Tube
Oral Pharynx
Pancreas
Pharyngeal Arches and Clefts
Surface Ectoderm

Entry 2

GEISHA Id	ISL2.Guidato.2003	Data Source	Publication
Complete cDNA Template Probe	show TTCCTGCTGCGGGTGTCTCCGGACCTGGAGTGGCACGTCGCCTGCCTCAAGTGCGCCGAGTGCGGGCAGCCGCTGGACG AGACCTGCACGTGCTTCCTGCGCGACGGCAAGGCCTACTGCAAGCGGGACTACGGCAGGCTCTTCGGCATCAAGTGCGC GCAGTGCCGGGCGGCCTTCAGCAGCAGCGACCTGGTGATGCGCGCCCGCGACCACGTCTACCACCTGGAGTGCTTCCGC TGCGCCGCCTGCGGCCGCCAGCTGCTGCCCGGGGATCAGTTCTGCCTGCGGGAGCGCGACCTGCTCTGCCGCGCCGACC ACGGGCCGCCCCCCGACGGCGCCGCCGCCCGCGGGCCCCGCAGCCCCGCGCCGCCGCCCGCGCACCTCGCAGAGCCGGT GCCCGGACGGCCGCCCGGCCCGCGGCCGCAGTCGCACAAAGCGGCCGAGAAGACCACCCGCGTGCGGACGGTGCTGAAC GAGAAGCAGCTGCACACGCTGCGGACCTGCTACGCCGCCAACCCGAGACCCGACGCCCTGATGAAGGAGCAGCTGGTGG AGATGACGGGGCTCAGCCCGCGCGTCATCCGCGTCTGGTTCCAGAACAAGCGCTGCAAGGACAAGAAGAAGTCCATCCT CATGAAGCAGCTCCAGCAGCAGCAGCACAGCGACAAGACGAGCCTGCAGGGCCTCACCGGGACGCCGCTGGTGGCCGGC AGCCCCGTCCGGCACGAGAGCGCCGTGCAGGGGAGCGCGGTGGAGGTGCAGACCTACCAGCCGCCCTGGAAGGCGCTCA GCGACTTCGCGCTGCAGAGCGACCTGGAGCCGCCCGCCGCCTTCCAGCAGCTGGTCTCCTTCTCCGAGTCCGGCTCTTT GGGCACGTCCTCCGGCAGCGACGTGACCTCGCTGTCCTCCCAGCTCCCCGACACCCCCAACAGCATGGTGCCCAGCCCG GCCGAGACGTGA
Citation	Guidato S, Prin F, Guthrie S. Somatic motoneurone specification in the hindbrain: the influence of somite-derived signals, retinoic acid and Hoxa3. Development. 2003 Jul;130(13):2981-96.
Copyright	Published by The Company of Biologists 2003. This material is protected by a copyright retained by the authors.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc #AB179553.1 ).

Stage

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Location (click to highlight)

Comments (click to highlight)

25-28

stage 28

Isthmus/MHB
Rhombomeres
Spinal Cord

Entry 3

GEISHA Id	ISL2.Anderson.2021	Data Source	Direct Submission
Complete cDNA Template Probe	show TTGTTGTTCGTTTGTTTTTATTAAGTCCAAAATATTTAACCCCACTATTCAACCGCTGACTCTGACAATAAATAGCAAT AACTTACTTTTGTTCGTTTAAAGGCTCAAACAATCCGCCCTCCGTCCGTCGCTATCGCCGGCAGCGCTGTCCCGTCGCA GCGCCCCGTCTCCGCGCCGCGGTGCTGCGGGAGGCGCCGGCGTGAGGCGGCCGCGACGGCCGCGGGGCTCCGACCCCCG TTCGGTTTGATTCGAGTTTTCGTTTCTGTTCCAGGCGAGGAAGAAGAGCCGGCGCCCCGCCGGGCAATCCGCTTTCATC GCGGAAAAGAAACATCGAAATCCGCAGCGCCGAACCTCCGCGCAACGAAATGAGCGGGGCGGGGGCTCGCTCTCTCTTT CTCTCTCCGGTCCGGTGAAGGCAGCGAGAATCCCGGCGCTTTTCGGCCGTCGGCAAGGTACGTTCGGTTTGGTTTTAAA TAGGAATAATTAAAAGACAAAGGCGCTCGTCCGGCGCGCTGGGCGCGGCGCGGGGCCGGGTGTCTCATGCAGGGAGCGC GGCATGCGGAGGTCCCGCGGCGGCGGGGGCCGGGCGGCCTCACGTCTCGGCCGGGCTGGGCACCATGCTGTTGGGGGTG TCGGGGAGCTGGGAGGACAGCGAGGTCACGTCGCTGCCGGAGGACGTGCCCAAAGAGCCGGACTCGGAGAAGGAGACCA GCTGCTGGAAGGCGGCGGGCGGCTCCAGGTCGCTCTGCAGCGCGAAGTCGCTGAGCGCCTTCCAGGGCGGCTGGTAGGT CTGCACCTCCACCGCGCTGCCCTGCACGGCGCTCTCGTGCCGGACGGGGCTGCCGGCCACCAGCGGCGTCCCGGTGAGG CCCTGCAGGCTCGTCTTGTCGCTGTGCTGCTGCTGCTGGAGCTGCTTCATGAGGATGGACTTCTTCTTGTCCNTGCAGC GCTTGTNCTGGAACCAGACGCGNATGANNNNNNGGCTGANCCCCGTCATCTCCNNNGCTGCTNCTTCATC
Comments	Images and probe sequence provided by Claire Anderson. Reference paper for probe: T.Tsuchida, M.Ensini, S.B.Morton, M.Baldassare, T.Edlund†T.M.Jessell, S.L.Pfaff. Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes. Cell, Volume 79, Issue 6, 16 December 1994, Pages 957-970.