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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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MBNL1
muscleblind like splicing regulator 1

Gene

Official Symbol	MBNL1
Official Full Name	muscleblind like splicing regulator 1
CGNC ID	52321
also known as	muscleblind-like protein 1\|muscleblind-like 1
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_001031322
Polypeptide	NP_001026493
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.4840

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	36945			FBgn0261642
Human	4154	ENSG00000152601		MIM:606516
Mouse	56758	ENSMUSG00000027763	All phenotypic alleles (3):Targeted, knock-out(1) Targeted, other(2)	MGI:1928482
Xenopus	100498648			6035556
Zebrafish	767696		ZDB-GENE-060929-704	ZFIN:ZDB-GENE-060929-704

Gene Ontology

Molecular Function	metal ion binding, RNA binding
Biological Process	mRNA processing, RNA splicing
Cellular Component	cytoplasm, nucleus

Links to other databases

Entrez Gene	425033
Ensembl Gene	ENSGALG00000010361
KEGG	gga:425033

Entry 1

GEISHA Id	MBNL1.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	AACCCCCTCAGCAGTAAGACATC
Reverse cDNA Template Primer	AATTAACCCTCACTAAAGGCTACGCTAATCAACACCTCCGC	cDNA Template Length	944
Forward cDNA Template Probe	show TTTGGTTCGTCATGCATCTGACCCAGTGCTTCTGCCGCCTTAGTTTAGAGTCACCAGTTAAGGCGTGACTGTGCGAAGG GAAGGCGCAGCCCGTCTGCAGAGCGTTTAGAGTCCTTTGACTTCTGACAGAGGCTGTGCAGAGAAGCAGAAGTAGTTCC TCAGACATTTGTCGCCGCGTCTCAGAAATGGCTTTTCCCTTTCCGGCAGCACAGCGAGCGCCATTTCTGAGACGGCTTT GGTTTGGAAACAGAACGGTGCCCTTTGACTGATCGGTACGAGCAAGGTAAGCGAAAACGTGGTTCTGAAAATAACACTG CAAAATAACACTCTGGTCTGCTGTACAGTCTATGGCACTTCATGAGAATCCGTAACAATGTGGTACTTAAAGCCATCGA CGTGCTTTAAAATAGACACGGTTGTGGTTTTGCTTGGCACATTCATCTCTGTCAGATACCTCTCTTACCGCTTCTTACA ATCCATTACATTAAAAATATTACTCTTAAACAAAAATTACTGTGCATGCACGCTCTCATCTATAATGGCAATTTTAAAT ACAAGGTGCACCTTTGTTATTTGTAAACCTTGAAAGAAATAAACTTACTTTAAAAAATTATATCTTGGTCTACAGACGT ACCAATACATAATAGATTCATGGTTACACCATAGTCTGTCTTTTCAAGGTGACATACACGGTTATGTAGGAAATTGGCC GCACACGCGAATCCGAGCGCGTACGCGCGCTCCTGCGCTAGAAAAGATAGACAATGTTGTAGTTCTTAGACAAGAAGAT CACCTCAGCACAAATATCAATTAAATGTACAAAGTATATAGGCAACAGTGTGCAGTGGATTCCCAAGTTCTCGTTCGTC TCCTTAACATGCAATGGTGTGGATGTCTTACTG

Stage

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Location (click to highlight)

Comments (click to highlight)

4-6

stage 5

Unlabeled

7-12

stage 8

stage 9

stage 11

Anterior Intestinal Portal
Blood Islands
Extraembryonic Mesoderm
Forebrain
Heart
Hindbrain
Lateral Plate Mesoderm
Midbrain
Neural Plate/Tube

13-18

stage 15

stage 16

Blood Islands
Dermomyotome
Eye
Head Mesenchyme
Heart
Hindbrain
Intermediate Mesoderm
Midbrain
Myotome
Neural Plate/Tube
Notochord
Pharyngeal Arches and Clefts
Sinus Venosus
Somites
Yolk Sack or Stalk

19-24

stage 20

Allantois
Ear/Otic Placode
Eye
Foregut
Head Mesenchyme
Leg Mesenchyme
Liver
Lung
Nasal Placode/Nerve
Notochord
Pharyngeal Arches and Clefts
Sclerotome
Wing Mesenchyme

25-26

stage 26

Foregut
Leg Mesenchyme
Liver
Lung
Mesonephros
Nasal Placode/Nerve
Pharyngeal Arches and Clefts
Sclerotome
Somatic Mesoderm
Spinal Cord
Spinal Ganglia and Nerves
Tail
Ventricles
Wing Mesenchyme

Entry 2

GEISHA Id	MBNL1.Vajda.2009	Data Source	Publication
Complete cDNA Template Probe	show ATGGCCGTCAGCGTCACGCCCATCCGCGACACCAAGTGGCTCACGCTGGAGGTGTGCCGGGAGTTCCAGAGGGGGACGT GCTCACGGCCGGACACGGAATGTAAATTTGCACACCCGTCGAAAAGCTGCCAGGTGGAGAACGGACGTGTCATCGCCTG CTTCGACTCATTGAAAGGGCGATGTTCGAGGGAGAACTGCAAGTACCTTCACCCGCCGCCGCACTTAAAAACGCAGCTG GAGATCAATGGCCGCAATAACCTGATCCAGCAGAAGAACATGGCCATGCTGGCCCAGCAGATGCAGCTTGCCAATGCCA TGATGCCCGGAGCCCCGCTGCAGCCTGTGCCCATGTTCTCCGTTGCGCCCAGCCTAGCCACCAATGCCTCGGCTGCCTT CAACCCCTACCTGGGGCCCGTGTCCCCAGGGCTGGTGCCGGCGGAGATCCTGCCCACCGCGCCCATGCTGGTGGCGGGC AACCCTGGTGTCCCGGTGCCTGCTGCCGCCGCTGCTGCTGCGCAGAAGCTGATGAGGACGGACAGGCTGGAGGTGTGTC GGGAGTACCAACGCGGGAACTGCAACCGGGGCGAGAACGACTGCCGGTTCGCTCACCCCGCCGACAGCGCCATGATCGA CACCAACGATAACACCGTTACGGTCTGCATGGATTACATCAAAGGGAGATGCTCACGGGAAAAGTGCAAATACTTCCAC CCTCCAGCACATCTGCAAGCCAAGATCAAGGCTGCCCAGTACCAGGTTAACCAGGCTGCAGCTGCCCAGGCAGCAGCGA CGGCGGCTGCCATGACTCAGTCGGCTGTCAAATCACTGAAGCGACCCCTCGAGGCAACCTTTGACCTGGGAATTCCTCA AGCTGTACTTCCCCCATTACCAAAGAGGCCTGCGCTTGAAAAAACCAATGGTGCCACCGCAGTGTTCAATACTGGTATT TTCCAATACCAGCAAGCTCTTGCCAACATGCAGCTGCAGCAGCACACAGCCTTTCTCCCACCAGGCTCAATATTGTGCA TGACACCCGCTACAAGTGTTGTTCCCATGGTGCACGGTGCTACGCCAGCCACTGTGTCTGCAGCAACAACATCTGCCAC AAGTGTTCCCTTCGCTGCAACAGCCACAGCCAACCAGATACCCATAATATCTGCCGAACATCTGACTAGCCACAAGTAT GTTACACAGATGTAG
Citation	Vajda NA, Brimacombe KR, LeMasters KE, Ladd AN. Muscleblind-like 1 is a negative regulator of TGF-β-dependent epithelial-mesenchymal transition of atrioventricular canal endocardial cells. Dev Dyn. 2009 December; 238(12): 32663272.
Copyright	Copyright © 2009 Wiley-Liss, Inc.
Comments	The probe was amplified by PCR using the following primers: 5_-ATGGCCGTCAGCGTCACGCCCATC-3_ and 5_-CTACA TCTGTGTAACATACTTGTG-3_ and was extracted from NCBI Acc# NM_001163324.