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| NTRK1 neurotrophic receptor tyrosine kinase 1 | The human orthologue of this gene is associated with the following human diseases: |
Gene | Official Symbol | NTRK1 | Official Full Name | neurotrophic receptor tyrosine kinase 1 | CGNC ID | 49757 | also known as | CTRKA, trkA, high affinity nerve growth factor receptor|neurotrophic tyrosine kinase, receptor, type 1|trk-A|tropomyosin receptor kinase | gene type | protein-coding |
| Genomic Map | | Sequence Information | | Gene Expression | | Orthology | | Gene Ontology | Molecular Function | ATP binding, nerve growth factor binding, nerve growth factor receptor activity, more...protein homodimerization activity, transmembrane receptor protein tyrosine kinase activity | Biological Process | axonogenesis involved in innervation, negative regulation of cell proliferation, more...negative regulation of neuron apoptotic process, nerve growth factor signaling pathway, neurotrophin TRK receptor signaling pathway, peptidyl-tyrosine phosphorylation, positive regulation of ERK1 and ERK2 cascade, positive regulation of neuron projection development, positive regulation of NF-kappaB transcription factor activity, positive regulation of Ras GTPase activity, positive regulation of Ras protein signal transduction, protein autophosphorylation, protein phosphorylation, sympathetic nervous system development | Cellular Component | early endosome membrane, integral component of plasma membrane, late endosome membrane |
| Links to other databases | |
Entry 1GEISHA Id | TRKA.Yang.2010 | Data Source | Publication | Complete cDNA Template Probe | show GATGCTTTCCAGGACAACCACAGGCTGAGCCATGTGAATCTCTCCTTCAATGCGTTGACCAGCCTGTCCTGGAAAACCT TCCAGTATCTGCCCCTGCAGGAGCTCATCCTGGAAGGAAACCCCTTCAATTGCTCCTGTGGGATCCGCTGGCTGCAGCT GTGGCAGAACGGGAGCCGTGCTGAGCTGGGCAACCAGTCGCTGCTCTGCTGGGAGGGCAGCATGCTTGTTGCCCTGGAC AGCCACCCCCTGCACGACTGTGAGCCCCCCACTGCCCGCATTGAGCACCCCGATGTGGTGCTGCGCCAAGGGGACAGCG TCAACCTCACCTGCCACATCTGGGGTGAGCCATCAGCCACCGGGGAGTGGGTGCTCCCTCACGTGGGATCAGAGCCATC TGTCACCAAGCTCTCGGAGTGGGAGCTTGTCCTGGAGATCAACAACATCTCCTCCAGCCTCAACCACAAGGATCTCACA TGCCGGGCAGAGAATGCAGTGGGGCTGGCAGAGGACAGCGTGATGCTGAATGTCACCTTCCCGCCGGTGATCCTGCTCC TCTCTGAGGCCATCCCGCAGCACTTCTGGTGCATCCCCTTCTCGGTGGACAGCAACCCAACGCCCAGAATCCTTTGGCT CTTCAATGGCTCGATGCTGCCTGAGGGGCCCTACATCCACACACGCATTGTGGAGTATGAGCCCAACTCCACCGTACTG CACGGCTGCCTCCAGCTCAACCGCCCCACACACGTCAACAACGGCAACTACACCCTCGTGGTGCAGAACCCCCTGGGCA GAGCCACCCGCAGCATCCAGGGCCGCTTCATGGATAACCCTTTCAGCTTCAGCCCCGAGGAGCCCATCCCCGTGTCCAT ATCTCCACTGGGCACAAGGAAC | Citation | Yang M, Cagle MC, Honig MG. Identification of cerebellin2 in chick and its preferential expression by subsets of developing sensory neurons and their targets in the dorsal horn. J Comp Neurol. 2010 Jul 15;518(14):2818-40.
| Copyright | Copyright © 2010 Wiley-Liss, Inc. | Comments | The cDNA template used to generate the probe was obtained by PCR as described in Yang et al. |
Entry 2GEISHA Id | TRKA.Apostolova.2007 | Data Source | Publication | Complete cDNA Template Probe | show TGCGATGCTGCCCGCCTGGCTCCGGCTGTGCCTGGCTGCGCTGCTGCTGCCCCCGGGAGCCGCCGTTCCTCCCGCCTGC CCCGCGCACTGCCGCTGCCCCGCGTCCCACACGCTGCGATGCCGGGAGCCCCTCACCGTGAGCAGCCTCAGCGCCCTGC TGCTGGGAGCCCACCGCCCCACCGACGTCATCATCGAGAACCAAGCGCTGCTGACATCTCTGACCCGGGATGACACCAG GATGCTGTGGGACCTCAGGCACCTCACCATCTCCAACTCGGGGCTGCAATACATATCCGACGATGCTTTCCAGGACAAC CACAGGCTGAGCCATGTGAATCTCTCCTTCAATGCGTTGACCAGCCTGTCCTGGAAAACCTTCCAGTATCTGCCCCTGC AGGAGCTCATCCTGGAAGGAAACCCCTTCAATTGCTCCTGTGGGATCCGCTGGCTGCAGCTGTGGCAGAACGGGAGCCG TGCTGAGCTGGGCAACCAGTCGCTGCTCTGCTGGGAGGGCAGCATGCTTGTTGCCCTGGACAGCCACCCCCTGCACGAC TGTGAGCCCCCCACTGCCCGCATTGAGCACCCCGATGTGGTGCTGCGCCAAGGGGACAGCGTCAACCTCACCTGCCACA TCTGGGGTGAGCCATCAGCCACCGGGGAGTGGGTGCTCCCTCACGTGGGATCAGAGCCATCTGTCACCAAGCTCTCGGA GTGGGAGCTTGTCCTGGAGATCAACAACATCTCCTCCAGCCTCAACCACAAGGATCTCACATGCCGGGCAGAGAATGCA GTGGGGCTGGCAGAGGACAGCGTGATGCTGAATGTCACCTTCCCGCCGGTGATCCTGCTCCTCTCTGAGGCCATCCCGC AGCACTTCTGGTGCATCCCCTTCTCGGTGGACAGCAACCCAACGCCCAGAATCCTTTGGCTCTTCAATGGCTCGATGCT GCCTGAGGGGCCCTACATCCACACACGCATTGTGGAGTATGAGCCCAACTCCACCGTACTGCACGGCTGCCTCCAGCTC AACCGCCCCACACACGTCAACAACGGCAACTACACCCTCGTGGTGCAGAACCCCCTGGGCAGAGCCACCCGCAGCATCC AGGGCCGCTTCATGGATAACCCTTTCAGCTTCAGCCCCGAGGAGCCCATCCCCGTGTCCATATCTCCACTGGGCACAAG GAACAGCTCTCTGGAGGGTCCTGTGGAGACAGCGGACGAGCACACATTTGGGGTCTCCGTGGCCGTGGCTTTGGCTGTC TTCGCCTCCCTCTTCCTCTCTGTCATGCTCATTGCGCTCAACAAGTGCGGGCACCGCTCCAAGTTCGGCATTAACCGAT CAGCCGTGCTGGCCCAGGAGGATGACCTGGCCATGTCACTGCACTTCATGAACCTGGGCAGCAGCCCCGTGTCCTCCAC AGAGAGCAAGCTGGACGGGCTGAAGAGCAACTTCATCGAGAACCCGCAGTACTTCTGCAACGCCTGTGTGCACCACGTG CAGCGCCGCGACATTGTGCTCAAGTGGGAGCTGGGAGAGGGCGCCTTTGGGAAGGTCTTCCTGGCCGAGTGTTCCCACC TCCTCCCGGAGCAGGAGAAGACATTGGTGGCTGTGAAGGCGCTGAAGGAGGTGACGGAGAGCGCGCGGCTCGACTTCCA GCGGGAAGCAGAGCTGCTGACGGTGCTGCAGCACGAACACATCGTCAAGTTCTACGGCGTGTGCACCGAGGGTGAGCCC CTCATCATGGTCTTCGAGTACATGAAGCATGGAGACCTCAACCGCTTCCTCAGGTCCCACGGGCCAGATGCCAAGATCC TGGACCAAGGGCAGGGGCAGCCCTGCGGGCAGCTGACACTGAGCCACATGCTGCAGATCGCCACGCAGATCGCCTCAGG GATGGTTTACCTGGCATCCCTGCACTTCGTGCACCGTGACCTGGCCACACGCAACTGCCTGGTGGGTCACGACCTGGTG GTGAAGATTGGGGACTTCGGCATGTCCCGCGATATCTACAGCACCGACTACTACCGGGTGGGCGGTCGGACCATGCTGC CCATCCGCTGGATGCCCCCTGAGAGCATCCTGTACCGCAAGTTCACCACTGAGAGTGACATCTGGAGCTTTGGCGTGGT GCTGTGGGAGATCTTCACCTATGGGAAGCAGCCCTGGTATCAACTCTCCAACACTGAGGCCATCGAGTGCATCACGCAG GGCCGGGAGCTGGAGCGGCCCCGCACGTGTCCCTCCGAGGTGTATGATATCATGCAGAGCTGCTGGCAGAGAGAGCCGC AGCAGCGCCAGCGCATCCAGGACATCCACAGCCGCCTGCAGGCCCTGGTCAAGACCCCTCCCATCTACCTGGACATCCT GGGGTGAGAGGGAACCCCATCATCCTCAAGCTGGCCGGAGCGCTCTGGCACCGCTCTCTCTGTCCCCCCACCCTGGACT GATGCCCTGACGCTGGAGAGGTCTTAAACCCTGTTTGTCACAGCGAGCCTCCTGGGGGGCTGTAGGGCTGGAGCTGTGC CCGCGGGGGGGCTGTGGCTGTGCATTTCCCCACTGTGGGTTTGTCCCTGGAGGGAGACAACCGGGACCCCCAGCCCCAC GGGGATCACTTGGCTGCTCAGTGCCATGGCTGCTCCATCCCTCCCCATCCCAGTGCCCAGCTGTGTGGATACCCCGCGT GCTCTCCCACTCTGCGGTGATCCTGGTTGGTAATAAAATTCTCCACCTCTCT | Citation | Apostolova G, Dorn R, Ka S, Hallböök F, Lundeberg J, Liser K, Hakim V, Brodski C, Michaelidis TM, Dechant G. Neurotransmitter phenotype-specific expression changes in developing sympathetic neurons. Mol Cell Neurosci. 2007 Jul;35(3):397-408. Epub 2007 Apr 1. | Copyright | Copyright © 2007 Elsevier Inc. All rights reserved. | Comments |
As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI NM_205378.1 |
Stage | Image (click image to view full size) | Location (click to highlight) | Comments (click to highlight) | 31-44 | | stage 44 | | stage 44 | | Spinal Ganglia and Nerves
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Entry 3GEISHA Id | TRKA.Karlsson.1998 | Data Source | GEISHA ISH Analysis | Complete cDNA Template Probe | show TGCGATGCTGCCCGCCTGGCTCCGGCTGTGCCTGGCTGCGCTGCTGCTGCCCCCGGGAGCCGCCGTTCCTCCCGCCTGC CCCGCGCACTGCCGCTGCCCCGCGTCCCACACGCTGCGATGCCGGGAGCCCCTCACCGTGAGCAGCCTCAGCGCCCTGC TGCTGGGAGCCCACCGCCCCACCGACGTCATCATCGAGAACCAAGCGCTGCTGACATCTCTGACCCGGGATGACACCAG GATGCTGTGGGACCTCAGGCACCTCACCATCTCCAACTCGGGGCTGCAATACATATCCGACGATGCTTTCCAGGACAAC CACAGGCTGAGCCATGTGAATCTCTCCTTCAATGCGTTGACCAGCCTGTCCTGGAAAACCTTCCAGTATCTGCCCCTGC AGGAGCTCATCCTGGAAGGAAACCCCTTCAATTGCTCCTGTGGGATCCGCTGGCTGCAGCTGTGGCAGAACGGGAGCCG TGCTGAGCTGGGCAACCAGTCGCTGCTCTGCTGGGAGGGCAGCATGCTTGTTGCCCTGGACAGCCACCCCCTGCACGAC TGTGAGCCCCCCACTGCCCGCATTGAGCACCCCGATGTGGTGCTGCGCCAAGGGGACAGCGTCAACCTCACCTGCCACA TCTGGGGTGAGCCATCAGCCACCGGGGAGTGGGTGCTCCCTCACGTGGGATCAGAGCCATCTGTCACCAAGCTCTCGGA GTGGGAGCTTGTCCTGGAGATCAACAACATCTCCTCCAGCCTCAACCACAAGGATCTCACATGCCGGGCAGAGAATGCA GTGGGGCTGGCAGAGGACAGCGTGATGCTGAATGTCACCTTCCCGCCGGTGATCCTGCTCCTCTCTGAGGCCATCCCGC AGCACTTCTGGTGCATCCCCTTCTCGGTGGACAGCAACCCAACGCCCAGAATCCTTTGGCTCTTCAATGGCTCGATGCT GCCTGAGGGGCCCTACATCCACACACGCATTGTGGAGTATGAGCCCAACTCCACCGTACTGCACGGCTGCCTCCAGCTC AACCGCCCCACACACGTCAACAACGGCAACTACACCCTCGTGGTGCAGAACCCCCTGGGCAGAGCCACCCGCAGCATCC AGGGCCGCTTCATGGATAACCCTTTCAGCTTCAGCCCCGAGGAGCCCATCCCCGTGTCCATATCTCCACTGGGCACAAG GAACAGCTCTCTGGAGGGTCCTGTGGAGACAGCGGACGAGCACACATTTGGGGTCTCCGTGGCCGTGGCTTTGGCTGTC TTCGCCTCCCTCTTCCTCTCTGTCATGCTCATTGCGCTCAACAAGTGCGGGCACCGCTCCAAGTTCGGCATTAACCGAT CAGCCGTGCTGGCCCAGGAGGATGACCTGGCCATGTCACTGCACTTCATGAACCTGGGCAGCAGCCCCGTGTCCTCCAC AGAGAGCAAGCTGGACGGGCTGAAGAGCAACTTCATCGAGAACCCGCAGTACTTCTGCAACGCCTGTGTGCACCACGTG CAGCGCCGCGACATTGTGCTCAAGTGGGAGCTGGGAGAGGGCGCCTTTGGGAAGGTCTTCCTGGCCGAGTGTTCCCACC TCCTCCCGGAGCAGGAGAAGACATTGGTGGCTGTGAAGGCGCTGAAGGAGGTGACGGAGAGCGCGCGGCTCGACTTCCA GCGGGAAGCAGAGCTGCTGACGGTGCTGCAGCACGAACACATCGTCAAGTTCTACGGCGTGTGCACCGAGGGTGAGCCC CTCATCATGGTCTTCGAGTACATGAAGCATGGAGACCTCAACCGCTTCCTCAGGTCCCACGGGCCAGATGCCAAGATCC TGGACCAAGGGCAGGGGCAGCCCTGCGGGCAGCTGACACTGAGCCACATGCTGCAGATCGCCACGCAGATCGCCTCAGG GATGGTTTACCTGGCATCCCTGCACTTCGTGCACCGTGACCTGGCCACACGCAACTGCCTGGTGGGTCACGACCTGGTG GTGAAGATTGGGGACTTCGGCATGTCCCGCGATATCTACAGCACCGACTACTACCGGGTGGGCGGTCGGACCATGCTGC CCATCCGCTGGATGCCCCCTGAGAGCATCCTGTACCGCAAGTTCACCACTGAGAGTGACATCTGGAGCTTTGGCGTGGT GCTGTGGGAGATCTTCACCTATGGGAAGCAGCCCTGGTATCAACTCTCCAACACTGAGGCCATCGAGTGCATCACGCAG GGCCGGGAGCTGGAGCGGCCCCGCACGTGTCCCTCCGAGGTGTATGATATCATGCAGAGCTGCTGGCAGAGAGAGCCGC AGCAGCGCCAGCGCATCCAGGACATCCACAGCCGCCTGCAGGCCCTGGTCAAGACCCCTCCCATCTACCTGGACATCCT GGGGTGAGAGGGAACCCCATCATCCTCAAGCTGGCCGGAGCGCTCTGGCACCGCTCTCTCTGTCCCCCCACCCTGGACT GATGCCCTGACGCTGGAGAGGTCTTAAACCCTGTTTGTCACAGCGAGCCTCCTGGGGGGCTGTAGGGCTGGAGCTGTGC CCGCGGGGGGGCTGTGGCTGTGCATTTCCCCACTGTGGGTTTGTCCCTGGAGGGAGACAACCGGGACCCCCAGCCCCAC GGGGATCACTTGGCTGCTCAGTGCCATGGCTGCTCCATCCCTCCCCATCCCAGTGCCCAGCTGTGTGGATACCCCGCGT GCTCTCCCACTCTGCGGTGATCCTGGTTGGTAATAAAATTCTCCACCTCTCT | Comments | Insufficient information provided in publication to verify exact sequence used to synthesize probe. Sequence was obtained from NCBI (NM_205378.1). Also known as: trkA; CTRKA |
Stage | Image (click image to view full size) | Location (click to highlight) | Comments (click to highlight) | 31-44 | | stage 35 | | stage 35 | | stage 41 | | stage 44 | | Retina
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| Data from NCBI Unigene EST Profile Unigene ID: Gga.579 |
MouseFrogFruit FlyZebra FinchZebrafish
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