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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase

Gene

Official Symbol	HMGCR
Official Full Name	3-hydroxy-3-methylglutaryl-CoA reductase
CGNC ID	11100
also known as	HMGR, 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC

Sequence Information

Genomic
RNA	NM_204485
Polypeptide	NP_989816

Gene Expression

In Situ Hybridization

GEISHA

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	42803			FBgn0263782
Human	3156	ENSG00000113161	MIM:142910	MIM:142910
Mouse	15357	ENSMUSG00000021670	All phenotypic alleles (4):Targeted, knock-out(1) Targeted, other(2) Gene trapped(1)	MGI:96159
Xenopus	100380121, 397750			5840592
Zebrafish	796384, 559054, 541479	ENSDARG00000052734, ENSDARG00000059301	ZDB-GENE-040401-2, ZDB-GENE-051108-1	ZFIN:ZDB-GENE-040401-2, ZFIN:ZDB-GENE-051108-1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Links to other databases

Entrez Gene	395145
Ensembl Gene	ENSGALG00000014948
KEGG	gga:395145

Entry 1

GEISHA Id	HMGCR.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	GCAACCCTGAGGAAACTTCGTC
Reverse cDNA Template Primer	ATTAACCCTCACTAAAGGTACCAGCCATAGCAGAACCCAC	cDNA Template Length	975
Forward cDNA Template Probe	show CAGAATTGTTAATTCACTTCAACTATATCTTCCGGTAGTTGTCTTCAGTACTTCTTTAACAACCTTGGCTGGAATGACT GCTTCACAGACAACAGACTTCCCTCTTCCCTCTATCCAATTGATAGCAGCAGGCTTTTTGTCTGTGCAGTAGTTACCGC TGATAGCTATAACCTGGAGATCGGGAAACTCTTCATTCAGCCTTGCCAGTGCTTTTTCAGTACCTTTTGAAATCATATT CATTCCCATTGCATCCCCTGTTTTGGACTGAAAACGAATGTAAAGGTTCCGACCAGCCAAGCTGATGAGAAGCTTTTGT AGGCGGGCAAACCTACTTGTGCTGTCAAAAGCTTCTTTCACTATTTTAAAGCCTTCAGGGCTTTCAAGCCAAGCTTTCA CTTCTGCAGCCTGGCAAGCAGAGGGCAGCCTTACAACAGGTCCTCGAGTCATCCCATCTGCAAGAATACGGCTCCTTGC TCCTCCACCAAGACATATTGCTCTACATCCTCTATTTGTGCTTGCTACAAGACATCCTTCTGTTGTTGCCATTGGAACC TGAAACTCTTTGTTATCCAGGTATAGTGGTCCTGCTACGCCTACAGGAATAGGCATATATCCAATCACGTTTTCACAGC AAGCTCCTAAAACCAAAGAATAATTATAATTCCTGTAAGGAAGATACTGCAAAGATGAGGGTTCAGGGAGTTTCTGAGA TAACATTTGTCTGCGAATAGACACTCCTCGCTCCTGAGTTTCCATCAGGGTTTCCAGTTTGTATGCAGGAATATGCTTT GCATTAACTAAGCTGATCACTTCAGCATCAGTAAGGAATTTTGCTCCCTTCTCTGTACTTCCAAGTATACGAACACATT CCTCAATAGAACGTGGTTCTTTAGGTAACTCAATTTCTTCCTCTTTTTTATTAANAACTGACGAAGTTCCCC

Stage

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Location (click to highlight)

Comments (click to highlight)

1-3

stage 3

Area Pellucida
Primitive Streak

4-6

stage 4

stage 5

Area Pellucida
Neural Plate/Tube
Primitive Streak

7-12

stage 7

stage 8

stage 9

stage 10

stage 12

Anterior Intestinal Portal
Area Opaca
Area Pellucida
Blood
Blood Islands
Extraembryonic Mesoderm
Head Mesenchyme
Headfold
Heart
Heart Tube
Intermediate Mesoderm
Lateral Plate Mesoderm
Neural Plate/Tube
Paraxial Mesoderm
Primitive Streak
Widespread Expression

13-18

stage 13

stage 17

Blood Islands
Head Mesenchyme
Heart
Intermediate Mesoderm
Lateral Plate Mesoderm
Neural Plate/Tube
Primitive Streak
Somites
Spinal Cord
Spinal Ganglia and Nerves
Widespread Expression

19-24

stage 20

Allantois
Eye
Forebrain
Hindbrain
Midbrain
Pharyngeal Arches and Clefts
Spinal Cord
Spinal Ganglia and Nerves

stage 25

Eye
Forebrain
Hindbrain
Midbrain
Pharyngeal Arches and Clefts
Spinal Cord
Spinal Ganglia and Nerves

Entry 2

GEISHA Id	HMGCR.Olivera-Martinez.2014	Data Source	Publication
Complete cDNA Template Probe	show TGGCGGTGGCCGCCGCGTCGTGCCCCGGGTGTCCTTGTCCGGGGAGGAGCGGCCGCCTCAGTTCGCACCGCGGCGGGAG GGAAGCAGGAAGCGGCAGGTTCTCGGCCGGGCGATTTGCTGACTGTAGAAAAACAGTTCTGAAAATGTTGTCCAGGCTT TTTCGAATGCATGGCCTTTTTGTGGCCTCTCATCCATGGGAAGTCATTGTGGGAACAGTGACCCTTACCATCTGTATGA TGTCAATGAAGATGTTCACTGGGAATGATAAGATCTGTGGCTGGAACTATGAGTGCCCAAAACTTGAAGAAGATGTTCT GAGCAGTGACATCATAATCCTGACAATCACACGCTGTATAGCAATCCTTTATATATATTTCCAGTTTCAGAACCTAAGG CAACTCGGATCAAAATACATTTTAGGTATTGCTGGTCTCTTCACAATCTTCTCAAGTTTTGTTTTTAGTACGGTGGTGA TTCACTTCTTGGATAAAGAACTGACAGGTTTAAATGAAGCTTTACCGTTCTTCCTCCTTCTGATTGATCTTTCAAGAGC AAGTGCTCTAGCCAAATTTGCACTAAGTTCCAATTCACAGGATGAAGTGAGAGAAAATATTTCACGTGGAATGGCAATT TTAGGTCCTACATTTACCCTGGATGCACTTGTGGAATGTCTTGTGATTGGCGTTGGTACTATGTCAGGAGTGCGACAAC TTGAAATCATGTGCTGCTTTGGCTGCATGTCTGTTCTCGCCAACTACTTTGTCTTCATGACCTTCTTTCCAGCTTGTGT GTCCTTGGTATTAGAGCTTTCTCGAGAGAGTCGTGAAGGACGTCCTATATGGCAGCTGAGTCATTTCGCTCGTGTTCTG GAAGAAGAAGAAAATAAACCAAACCCTGTAACACAGAGGGTCAAAATGATTATGTCACTGGGTTTGGTTCTTGTTCATG CACACAGTCGCTGGATAGCGGAGCCAGCTTCTCAAAATGGTACAGTAGAAAATGCAGTGGGATTGGATGAGAATGCACC AAAGAGAATTGAACCTAATGTTTCACTGTGGCAGTTCTACCTTTCTCGAATGGCCAGTATGGATATTGAACAAGTAATC ACTCTTGGCTTAGCCTTTCTCCTTGCTGTGAAATACATTTTCTTTGAACAAGCAGAGACCGAATCCACGCTTTCATTGA AGAATCCCATAACATCTCCTGTGACGGTCCAGAAAAAGGTCCCTGAGAATTGCTGCAGGAAACAATCTGGACTTTTGAA AAATAGTCAGAAGACTAACACAGTAGAAGAAGCTTTTGTTGCTAAAGATGGAAATGCTGAAGTCATAAAGCCTGTGTTA GCAGAGTCATCAACCAAAGCTACATTTGTAGTTGGCAGCTGCAACCCTGAGGAAACTTCGTCAGTTCTTAATAAAAAAG AGGAAGAAATTGAGTTACCTAAAGAACCACGTTCTATTGAGGAATGTGTTCGTATACTTGGAAGTACAGAGAAGGGAGC AAAATTCCTTACTGATGCTGAAGTGATCAGCTTAGTTAATGCAAAGCATATTCCTGCATACAAACTGGAAACCCTGATG GAAACTCAGGAGCGAGGAGTGTCTATTCGCAGACAAATGTTATCTCAGAAACTCCCTGAACCCTCATCTTTGCAGTATC TTCCTTACAGGAATTATAATTATTCTTTGGTTTTAGGAGCTTGCTGTGAAAACGTGATTGGATATATGCCTATTCCTGT AGGCGTAGCAGGACCACTATACCTGGATAACAAAGAGTTTCAGGTTCCAATGGCAACAACAGAAGGATGTCTTGTAGCA AGCACAAATAGAGGATGTAGAGCAATATGTCTTGGTGGAGGAGCAAGGAGCCGTATTCTTGCAGATGGGATGACTCGAG GACCTGTTGTAAGGCTGCCCTCTGCTTGCCAGGCTGCAGAAGTGAAAGCTTGGCTTGAAAGCCCTGAAGGCTTTAAAAT AGTGAAAGAAGCTTTTGACAGCACAAGTAGGTTTGCCCGCCTACAAAAGCTTCTCATCAGCTTGGCTGGTCGGAACCTT TACATTCGTTTTCAGTCCAAAACAGGGGATGCAATGGGAATGAATATGATTTCAAAAGGTACTGAAAAAGCACTGGCAA GGCTGAATGAAGAGTTTCCCGATCTCCAGGTTATAGCTATCAGCGGTAACTACTGCACAGACAAAAAGCCTGCTGCTAT CAATTGGATAGAGGGAAGAGGGAAGTCTGTTGTCTGTGAAGCAGTCATTCCAGCCAAGGTTGTTAAAGAAGTACTGAAG ACAACTACGGAAGATATAGTTGAAGTGAATATAAACAAAAATCTGGTGGGTTCTGCTATGGCTGGTAGCATAGGTGGCT ACAACGCGCATGCTGCAAACATTGTTACAGCTATCTACATTGCCTGTGGTCAGGATGCTGCTCAGAATGTAGGCAGCTC TAACTGCATCACTTTGATGGAGCGTACTGGTTCCACCAGTGAAGACCTCTATATCAGCTGCACAATGCCATCTATAGAG ATAGGGACTGTTGGAGGAGGCACCAACTTGCTACCACAACAGGCCTGTTTGCAGATGTTGGGGGTTCAAGGTGCAAGCC AAGACAACCCTGGTGAAAATGCCCGCCAGCTTGCTAAAATCGTGTGTGCTACAGTGATGGCTGGGGAGTTATCGCTAAT GGCAGCTCTTGCAGCTGGGCATCTAGTCAAAAGCCACATGATCCACAACAGGTCAAAAATAAATCTACAAGATCTTCAA GGAACCTGCACTAAGAAGGCAGCTTGAATACTACAGCTTTGAAATTAAGCAACTGACTTAGGAGTAAAGGGGAAAAAAA TAATATAATCTGTGAAGCTTAGAATGAAAATCACCTTCAAGTCACTGATTTCTATGGACAGTAATCTGAGAGATAATGG ACTTGTGTGAGACTACTTATGCCTTTTATGTTCTTCAATGATTAGAGATGACTTCATGAAAGAAGTGTTGTCAGCTGTC TTAAATATAGTTTTGGAATTCTTACTCTTAAGCATCATTTTCTGAAAAGTCAGTCACGTGTTTTTACAGGTTGAGATTA TTTTGACAAGTAAACTGGTAATTAGGAAGGTGAAATATGATGTGTACTCTGTACAGTTGTTTTTTGTTGTTGTTTTGTT TCTTTCTTGAGGGGGAGGGGGATCGTTGATTGATTGTTTTTGTTTGTCTAACCTTGGCTTTAATGCATTGGTCCTTCTG TAGTAATGGCGAACCTAATTGTTTTCCATGAATTCCCAGTTTTAATTTTGCTAAAATGTTGAAGTTAGGTCTTACGCTC TGAGACAGTTTTTATCAGATCACATTAGCCCTACAGAAACCTGTCTACTTCTAGTACTTAATTTTCTGCAGCTAAGCAA CATTCAGTGTGTATCTTCACAATTTAGATTATTACTTAAAGGAGAACTTGTGACCTACAAAGTGCTGAACTGTTAAATT ATAGTATGTACTGAAGTAGGAAAAAAACAACAGTGTCTTAACTGTTCTGTCATTTAGTTCAGGTAC
Citation	Isabel Olivera-Martinez, Nick Schurch, Roman A Li, Junfang Song, Pamela A Halley, Raman M Das, Dave W Burt, Geoffrey J Barton, Kate G Storey. Major transcriptome re-organisation and abrupt changes in signalling, cell cycle and chromatin regulation at neural differentiation in vivo. Development 2014 Aug;141(16):3266-76. Epub 2014 Jul 25. DOI: 10.1242/dev.112623.
Copyright	Copyright © 2014. Published by The Company of Biologists Ltd.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence above was obtained from NCBI (accession number NM_204485.2).