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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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CA2
carbonic anhydrase 2

The human orthologue of this gene is associated
with the following human disease:

Osteopetrosis, autosomal recessive 3, with renal tubular acidosis

Gene

Official Symbol	CA2
Official Full Name	carbonic anhydrase 2
CGNC ID	11834
also known as	carbonic anhydrase 2\|CA-II\|carbonate dehydratase II\|carbonic anhydrase II
gene type	protein-coding

Genomic Map

	Ensembl
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_205317
Polypeptide	NP_990648
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.3986

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly
Human	760	ENSG00000104267	MIM:259730	MIM:611492
Mouse	12349	ENSMUSG00000027562	All phenotypic alleles (2):Chemically induced(1) Targeted, knock-out(1)	MGI:88269
Xenopus	548446, 379772			484347
Zebrafish	30331, 387526	ENSDARG00000011166, ENSDARG00000014488	ZDB-GENE-980526-39, ZDB-GENE-031219-5	ZFIN:ZDB-GENE-980526-39, ZFIN:ZDB-GENE-031219-5

Gene Ontology

Molecular Function	carbonate dehydratase activity, zinc ion binding
Biological Process	angiotensin-activated signaling pathway, carbon dioxide transport, morphogenesis of an epithelium, more...
Cellular Component	apical part of cell, cytoplasm, cytosol, plasma membrane

Links to other databases

Entrez Gene	396257
Ensembl Gene	ENSGALG00000015862
KEGG	gga:396257

Entry 1

GEISHA Id	CA2.Alev.2010	Data Source	Publication
Complete cDNA Template Probe	show GAGCGCTGGATGGAGTCTACAGGTTGGTGCAGTTTCACATTCACTGGGGATCCTGTGAGGGCCAGGGCTCTGAGCACAC TGTGGATGGCGTGAAGTACGATGCAGAGCTTCATATTGTTCACTGGAATGTAAAATATGGCAAATTTGCTGAAGCTCTG AAGCATCCTGATGGTTTGGCCGTCGTAGGCATCTTCATGAAGGTAGGGAATGCCAAACCTGAAATACAGAAAGTTGTTG ATGCTCTGAACTCCATTCAAACCAAGGGGAAACAAGCTTCTTTCACAAACTTTGACCCTACTGGACTGCTGCCTCCATG CAGAGACTATTGGACGTACCCTGGCTCCCTGACTACTCCACCACTGCATGAATGTGTGATTTGGCATGTTCTGAAGGAG CCCATCACTGTCAGCTCTGAGCAGATGTGCAAACTCCGTGGCCTTTGCTTCAGTGCTGAGAATGAGCCGGTGTGCCGCA TGGTGGACAACTGGCGCCCATGCCAGCCTCTAAAGAG
Citation	Alev C, Wu Y, Kasukawa T, Jakt LM, Ueda HR, Sheng G. Transcriptomic landscape of the primitive streak. Development. 2010 Sep 1;137(17):2863-74. Epub 2010 Jul 28.
Copyright	Published by The Company of Biologists 2010. This material is protected by a copyright retained by the authors. Permission granted by Dr. G Sheng.
Comments	The probe for CA2 was amplified by PCR using the following primers: 5′-GAGCGCTGGATGGAGTCTAC-3′ and 5′-CTCTTTAGAGGCTGGCATGG-3′.

Stage

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Location (click to highlight)

Comments (click to highlight)

stage 4

Neural Plate/Tube

Entry 2

GEISHA Id	CAII.Li.2008	Data Source	Publication
Complete cDNA Template Probe	show CCCGACGCGGCTCCGCGGCGGGAGGATCGCGGGTTATAAGCGGACCTCTCTCTCTCCGCCCCCGAGCGAAGTCTCCCTC CGCCCCCGCCCGCGCTCCCCACCCCTTCCTCCGGCCGCGGAGAAGGGCATGGAGTTCGCGGGAGCCTATAAAAGCCCCT GACAGCCCGCCGAGGCCACGGCGTTGCGATAGCCGACGGAGCCGGGCCGGCGCACCATGTCCCATCACTGGGGGTACGA CAGCCACAACGGACCCGCGCACTGGCACGAGCACTTCCCCATCGCCAATGGGGAGCGCCAGTCGCCCATCGCCATCAGC ACCAAAGCCGCCCGCTACGACCCCGCGCTGAAGCCCCTCAGCTTCAGCTACGATGCCGGCACGGCCAAAGCCATCGTCA ACAACGGGCACTCCTTCAACGTGGAGTTTGACGACTCCTCCGACAAGTCAGTGCTGCAAGGAGGAGCGCTGGATGGAGT CTACAGGTTGGTGCAGTTTCACATTCACTGGGGATCCTGTGAGGGCCAGGGCTCTGAGCACACTGTGGATGGCGTGAAG TACGATGCAGAGCTTCATATTGTTCACTGGAATGTAAAATATGGCAAATTTGCTGAAGCTCTGAAGCATCCTGATGGTT TGGCCGTCGTAGGCATCTTCATGAAGGTAGGGAATGCCAAACCTGAAATACAGAAAGTTGTTGATGCTCTGAACTCCAT TCAAACCAAGGGGAAACAAGCTTCTTTCACAAACTTTGACCCTACTGGACTGCTGCCTCCATGCAGAGACTATTGGACG TACCCTGGCTCCCTGACTACTCCACCACTGCATGAATGTGTGATTTGGCATGTTCTGAAGGAGCCCATCACTGTCAGCT CTGAGCAGATGTGCAAACTCCGTGGCCTTTGCTTCAGTGCTGAGAATGAGCCGGTGTGCCGCATGGTGGACAACTGGCG CCCATGCCAGCCTCTAAAGAGCAGGGAAGTCAGAGCTTCCTTCCAGTAACCTCAGCGATGAGTGTGTTAGAAACTGCTG TGTTTGCGAGGAACCCTTTTTGCTAAGCACAAATCAAACCTTTGCCATGTGTGCCCTGGCAACATCTTGTCTCCCATAT TCATTCTCTCTTTCGCTCTGCATCTAAAATGCCAGCTAATGAAATGTGAAAGGCTCTTGGCCAAACAGGAAGGGGTTCT TCATGTGTGGAGCTGGGGAAAACCTGAGGGGGGCTGTGTGCATTTTGATGACTTACTGCGACTGACATTTTGGAAAAAA CAAAAACAAACAAAAAAAAACTATATTGGCTGTTTGGGAGAGCATATGGTGAGAGCAAAATAAGCCATTCTGAGAAACC TCATCCACTGGTGTGATAGTACACATAACTAATGATAACTTGAAGCTTTGTGAAAAGCACAGGAAAACAAAATATAGGT ATAGTATAGGAAAAAAAAAAAAA
Citation	Li X, Glubrecht DD, Mita R, Godbout R. Expression of AP-2delta in the developing chick retina. Dev Dyn. 2008 Nov;237(11):3210-21.
Copyright	Copyright © 2008 Wiley-Liss, Inc.
Comments	As insufficient information is provided in publication to verify exact sequence used to synthesize probe, the sequence below was obtained from NCBI (acc # NM_205317).