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A chicken embryo gene expression database

	Anatomical Location
	Stage
	Gene Name
	GEISHA ID
	Multiple Parameters

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MSTN
myostatin

The human orthologue of this gene is associated
with the following human disease:

Muscle hypertrophy

Gene

Official Symbol	MSTN
Official Full Name	myostatin
CGNC ID	16892
also known as	GDF-8, GDF8, growth/differentiation factor 8, MSTN, Myostatin
gene type	protein-coding

Genomic Map

	Ensembl ID not known
	NCBI
	UCSC
	Gallus-Browse

Sequence Information

Genomic
RNA	NM_001001461
Polypeptide	NP_001001461
Sequence Clusters/ESTs	Unigene

Gene Expression

In Situ Hybridization	GEISHA
EST Profile	Gga.560

Orthology

	Entrez Gene	Ensembl Gene	Genetic Phenotypes	MOD
Fruit Fly	43811			FBgn0026199
Human	2660	ENSG00000138379	MIM:601788	MIM:601788
Mouse	17700	ENSMUSG00000026100	All phenotypic alleles (7):Spontaneous(1) Chemically induced(1) Targeted, knock-out(2) Targeted, other(3)	MGI:95691
Xenopus	100491923			855712
Zebrafish	798441, 445816	ENSDARG00000069133, ENSDARG00000042947	ZDB-GENE-990415-165, ZDB-GENE-050208-735	ZFIN:ZDB-GENE-990415-165, ZFIN:ZDB-GENE-050208-735

Gene Ontology

Molecular Function	cytokine activity, growth factor activity, identical protein binding
Biological Process	embryo development ending in birth or egg hatching, growth, more...
Cellular Component	extracellular space

Links to other databases

Entrez Gene	373964
Ensembl Gene
KEGG	gga:373964

Entry 1

GEISHA Id	MSTN.UApcr	Data Source	GEISHA ISH Analysis
Forward cDNA Template Primer	TTATAAAAGCTTGCGGCCGCAGAATATTGCCACAACCGAGACGATTATC
Reverse cDNA Template Primer	GCTCTAGAAATTAACCCTCACTAAAGGAGCCTCTGGGATTTGCTTGG	cDNA Template Length	668
Forward cDNA Template Probe	show AAACAATCCTACGGAGTCTGATTTTCTTGTACAATGGAGGGAAAACCAAAATGTTCGCTTCTTTAAGTTTAGCTCTAAA ATACAATATAACAAAGTAGTAAAGGCACAATTATGGATATACTTGAGGCAAGTCCAAAAACCTACAACGGTGTTTGTGC AGATCCTGAGACTCATTAAGCCCATGAAAGACGGTACAAGATATACTGGAATTCGATCTTTGAAACTTGACATGAACCC AGGCACTGGTATCTGGCAGAGTATTGATGTGAAGACAGTGCTGCAAAATTGGCTCAAACAGCCAGAATCCAATTTAGGC ATCGAAATAAAAGCTTTTGATGAGACTGGACGAGATCTTGCTGTCACATTCCCAGGACCGGGTGAAGATGGATTGAACC CATTTTTAGAGGTCAGAGTTACAGACACACCGAAACGGTCCCGCAGAGATTTTGGCCTTGACTGTGATGAGCACTCAAC GGAATCCCGATGTTGTCGCTACCCGCTGACAGTGGATTTCGAAGCTTTTGGATGGGACTGGATTATAGCACCTAAAAGA TACAAAGCCAATTACTGCTCCGGAGAATGCGAATTTGTGTTTCTACAGAAATACCCGCACACTCACCTGGTACACCAAG CAAATCCCAGAGGCTCCTTTAGTGAGGGTTAATATCTAGAGCAAAA
Reverse cDNA Template Probe	show TTGTACCAGGGTGAGTGTGCGGGTATTTCTGTAGAAACACAAATTCGCATTCTCCGGAGCAGTAATTGGCTTTGTATCT TTTAGGTGCTATAATCCAGTCCCATCCAAAAGCTTCGAAATCCACTGTCAGCGGGTAGCGACAACATCGGGATTCCGTT GAGTGCTCATCACAGTCAAGGCCAAAATCTCTGCGGGACCGTTTCGGTGTGTCTGTAACTCTGACCTCTAAAAATGGGT TCAATCCATCTTCACCCGGTCCTGGGAATGTGACAGCAAGATCTCGTCCAGTCTCATCAAAAGCTTTTATTTCGATGCC TAAATTGGATTCAGGCTGTTTGAGCCAATTTTGCAGCACTGTCTTCACATCAATACTCTGCCAGATACCAGTGCCTGGG TTCATGTCAAGTTTCAAAGATCGAATTCCAGTATATCTTGTACCGTCTTTCATGGGCTTAATGAGTCTCAGGATCTGCA CAAACACCGTTGTAGGTTTTTGGACTTGCCTCAAGTATATCCATAATTGTGCCTTTACTACTTTGTTATATTGTATTTT AGAGCTAAACTTAAAGAAGCAACATTTTGGTTTTCCCTCCATTTGTACAAGAAAATCAGACTCCGTAGGCATTGTGATA ATCGTCTCGGTTGTGGCAATATTCTGCGGCCGCAAGCTTTTATAAAAA
Comments	No specific expression detected at or below stage 13.

no images

Entry 2

GEISHA Id	Myostatin.Amthor.2002	Data Source	Publication
Complete cDNA Template Probe	show ATGCAAAAGCTAGCAGTCTATGTTTATATTTACCTGTTCATGCAGATCGCGGTTGATCCAGTGGCTCTGGATGGCAGTA GTCAGCCCACAGAGAACGCTGAAAAAGACGGACTGTGCAATGCTTGTACGTGGAGACAGAATACAAAATCCTCCAGAAT AGAAGCCATAAAAATTCAAATCCTCAGCAAACTGCGCCTGGAACAAGCACCTAACATTAGCAGGGACGTTATTAAGCAG CTTTTACCCAAAGCTCCTCCACTGCAGGAACTGATTGATCAGTATGATGTCCAGAGGGACGACAGTAGCGATGGCTCTT TGGAAGACGATGACTATCATGCCACAACCGAGACGATTATCACAATGCCTACGGAGTCTGATTTTCTTGTACAAATGGA GGGAAAACCAAAATGTTGCTTCTTTAAGTTTAGCTCTAAAATACAATATAACAAAGTAGTAAAGGCACAATTATGGATA TACTTGAGGCAAGTCCAAAAACCTACAACGGTGTTTGTGCAGATCCTGAGACTCATTAAGCCCATGAAAGACGGTACAA GATATACTGGAATTCGATCTTTGAAACTTGACATGAACCCAGGCACTGGTATCTGGCAGAGTATTGATGTGAAGACAGT GCTGCAAAATTGGCTCAAACAGCCTGAATCCAATTTAGGCATCGAAATAAAAGCTTTTGATGAGACTGGACGAGATCTT GCTGTCACATTCCCAGGACCGGGTGAAGATGGATTGAACCCATTTTTAGAGGTCAGAGTTACAGACACACCGAAACGGT CCCGCAGAGATTTTGGCCTTGACTGTGATGAGCACTCAACGGAATCCCGATGTTGTCGCTACCCGCTGACAGTGGATTT CGAAGCTTTTGGATGGGACTGGATTATAGCACCTAAAAGATACAAAGCCAATTACTGCTCCGGAGAATGTGAATTTGTG TTTCTACAGAAATACCCGCACACTCACCTGGTACACCAAGCAAATCCCAGAGGCTCAGCAGGCCCTTGCTGCACACCCA CCAAGATGTCCCCTATAAACATGCTGTATTTCAATGGAAAAGAACAAATAATATATGGAAAGATACCAGCCATGGTTGT AGATCGTTGCGGGTGCTCATGA
Citation	Amthor H, Huang R, McKinnell I, Christ B, Kambadur R, Sharma M, Patel K. The regulation and action of myostatin as a negative regulator of muscle development during avian embryogenesis. Dev Biol. 2002 Nov 15;251(2):241-57.
Copyright	"Reprinted from Dev Biol., 251(2), Amthor H, Huang R, McKinnell I, Christ B, Kambadur R, Sharma M, Patel K, The regulation and action of myostatin as a negative regulator of muscle development during avian embryogenesis, 241-57, Copyright (2002), with permission from Elsevier". Copyright © 2007 Elsevier B.V. All rights reserved.
Comments	According to the authors,"chick myostatin, 1-kb fragment was a kind gift from Professor Se Jin Lee;" As information provided wa insufficient to verify exact sequence used to synthesize probe, the sequence below was obtained form NCB1 (acc # NM_001001461).